EKS-MEG-00344

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-MEG-00344

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/DAPK	407.2	2.1E-122	1	253	253

Status

Unreviewed

Ensembl Protein

ENSMGAP00000012961

UniProt Accession

G1NI85;

Protein Name

Protein Synonyms/Alias

Gene Name

STK17A

Gene Synonyms/Alias

STK17A;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMGAG00000012311	ENSMGAP00000018478	ENSMGAT00000018674
ENSMGAG00000012311	ENSMGAP00000012961	ENSMGAT00000013862

Organism

Meleagris gallopavo

Functional Description

Protein Length

349

Protein Sequence
(FASTA)

RGKFAVVKKC IQKDTEREFA AKFMRKRRKG QDCRMEIIHE IAVLELAQCN LWVINLHEVY 60

ETATEMILVL EYAAGGEIFD QCVAEREEAF KEKDVKRLMK QILEGVSFLH RNNVVHLDLK 120

PQNILLTSKS PLGDIKIVDF GLSRIVKSSE ELREIMGTPE YVAPEILSYD PISTATDMWS 180

IGVLAYIMLT GISPFLGDDK QETFLNISQM NVSYSGEDFD LVSESAVDFM KTLLVKKPEE 240

RATAEECLQH PWLEQSDEPT CRAWNKSAGG ESGDVIQKNA DSASEKPVDV EKAEEEESMM 300

TEELIVVASY TLGQCRQSEK EKATEQKAIS KRFKFEEPLL QEIPGEFIY 349

Nucleotide Sequence
(FASTA)

AGAGGAAAAT TTGCAGTGGT GAAGAAATGT ATCCAAAAAG ACACTGAAAG AGAGTTTGCA 60

GCAAAGTTCA TGAGAAAAAG AAGAAAGGGC CAAGACTGTC GGATGGAAAT AATCCATGAA 120

ATTGCAGTCC TTGAGTTGGC ACAATGCAAC CTTTGGGTCA TTAACCTGCA TGAAGTTTAT 180

GAAACTGCAA CGGAGATGAT TTTAGTCCTG GAATATGCTG CTGGAGGTGA AATCTTTGAC 240

CAGTGTGTTG CTGAAAGAGA GGAGGCCTTC AAAGAGAAAG ATGTGAAACG ACTTATGAAG 300

CAGATCTTAG AAGGAGTTTC ATTCTTGCAC AGAAACAATG TTGTTCATCT TGACTTAAAG 360

CCACAAAACA TTCTACTAAC CAGTAAGTCT CCACTGGGAG ACATAAAGAT AGTGGATTTT 420

GGCCTTTCCA GGATAGTGAA GAGCAGTGAG GAATTAAGAG AAATTATGGG AACTCCAGAA 480

TATGTTGCTC CTGAAATTCT GAGTTATGAC CCAATCAGTA CAGCAACCGA TATGTGGAGC 540

ATTGGAGTAC TGGCATATAT TATGCTCACA GGGATATCAC CCTTCTTAGG GGATGATAAA 600

CAAGAAACAT TCTTAAATAT ATCTCAAATG AATGTAAGTT ACTCTGGAGA AGACTTTGAC 660

CTCGTATCAG AGTCTGCTGT GGATTTCATG AAAACATTAC TGGTGAAGAA ACCTGAGGAA 720

CGGGCAACTG CTGAAGAATG TCTGCAGCAC CCCTGGTTAG AACAAAGTGA TGAACCTACT 780

TGCAGGGCCT GGAATAAGAG TGCAGGAGGG GAGAGCGGTG ATGTCATCCA GAAAAATGCA 840

GATTCTGCCT CTGAAAAACC TGTAGATGTT GAGAAAGCTG AAGAGGAAGA ATCAATGATG 900

ACAGAAGAGC TAATTGTAGT AGCTTCGTAT ACGCTGGGAC AATGTAGGCA GTCAGAAAAA 960

GAAAAAGCAA CTGAGCAGAA AGCCATTTCC AAACGATTTA AGTTTGAGGA ACCATTGCTG 1020

CAAGAAATAC CAGGAGAATT CATTTATTGA 1050

Domain Profile

S: 9     sGkfavvrkcrekstGkeyaakflkkrrlkssrrgvsreeierevavlkeirsepnvinl  68

         +Gkfavv+kc++k+t +e+aakf++krr    +++++r+ei +e+avl++++ + +vinl

Q: 1     RGKFAVVKKCIQKDTEREFAAKFMRKRR----KGQDCRMEIIHEIAVLELAQCNLWVINL  56

         79**************************....****************************

S: 69    hevyenksdvililelvaGGelfd..llaekeslseeeatellkqilegvkylhskkivh  126

         hevye+++++il+le++aGGe+fd  +++++e+++e+++++l+kqilegv +lh +++vh

Q: 57    HEVYETATEMILVLEYAAGGEIFDqcVAEREEAFKEKDVKRLMKQILEGVSFLHRNNVVH  116

         ************************988899******************************

S: 127   ldlkPenillldkkvpkgdiklidfGlsrkieegaelkeilGtPefvaPeivnyeplsle  186

         ldlkP+nill++k+ p gdik++dfGlsr +++++el+ei+GtPe+vaPei++y+p+s++

Q: 117   LDLKPQNILLTSKS-PLGDIKIVDFGLSRIVKSSEELREIMGTPEYVAPEILSYDPISTA  175

         **************.*********************************************

S: 187   tdmwsiGvityillsgasPflGdtkqetllnisavnldfseelfssvselakdfirrllv  246

         tdmwsiGv++yi+l+g+sPflGd+kqet+lnis++n+++s e f+ vse+a+df+++llv

Q: 176   TDMWSIGVLAYIMLTGISPFLGDDKQETFLNISQMNVSYSGEDFDLVSESAVDFMKTLLV  235

         ************************************************************

S: 247   kdpekrltieeclehswl  264

         k+pe+r+t+eecl+h+wl

Q: 236   KKPEERATAEECLQHPWL  253

         *****************7

Domain Sequence
(FASTA)

RGKFAVVKKC IQKDTEREFA AKFMRKRRKG QDCRMEIIHE IAVLELAQCN LWVINLHEVY 60

ETATEMILVL EYAAGGEIFD QCVAEREEAF KEKDVKRLMK QILEGVSFLH RNNVVHLDLK 120

PQNILLTSKS PLGDIKIVDF GLSRIVKSSE ELREIMGTPE YVAPEILSYD PISTATDMWS 180

IGVLAYIMLT GISPFLGDDK QETFLNISQM NVSYSGEDFD LVSESAVDFM KTLLVKKPEE 240

RATAEECLQH PWL 253

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005634	; C:nucleus
GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0006917	; P:induction of apoptosis
GO:0007243	; P:intracellular protein kinase cascade
GO:2000377	; P:regulation of reactive oxygen species metabolic process

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013