EPS-MEG-00039

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-MEG-00039

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPM/PP2C	86.1	2.5E-24	43	322	280

Status

Unreviewed

Ensembl Protein

ENSMGAP00000013060

UniProt Accession

G1NIF7;

Protein Name

Protein Synonyms/Alias

Gene Name

TAB1

Gene Synonyms/Alias

TAB1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMGAG00000012394	ENSMGAP00000013060	ENSMGAT00000013962
ENSMGAG00000012394	ENSMGAP00000013048	ENSMGAT00000013950

Organism

Meleagris gallopavo

Functional Description

Protein Length

426

Protein Sequence
(FASTA)

EQQPSWTDDL PSCHLSGVGS APNRSYSADG KGTEGHPLED NWLKFRSENN CYLYGVFNGY 60

DGNRVTNFVG QRLSAELLLG QLHADHSDAD VRRVLLQAFD VVERSFLESI DDALAEKASL 120

QSQLPEGVPH HQLPPQYQKI VERLKVVEQE ISGGAMAIVA VVLNNKLYIA NVGTNRALLC 180

KSTVDGLQVT QLNVDHTTEN EDELFRFSQL GLDAGKIKQV GTIRGQESTR RIGDYKVKYG 240

YTDIELLSAA KSKPIIAEPE IHGGHSLDGV TGFLVLMSEG LYKALEAAHG PGQANQEIAA 300

MIATEFAKQT SLDAVAQAVV DRVKRIHCDT FASGGERSKF CPRHEDMTLL VRNFGYPLGE 360

MSQPTLTPTQ GGRVYPVSVP YSSSQSTSKT SVTLSLVMPS QGQMVNGAHS SSWMKPPPPS 420

LTKAPL 426

Nucleotide Sequence
(FASTA)

GAACAGCAGC CCAGCTGGAC AGATGACCTG CCGTCCTGCC ATCTCTCTGG GGTGGGCTCA 60

GCTCCAAACC GTTCCTACAG TGCGGATGGC AAAGGTACAG AGGGTCACCC CTTGGAAGAT 120

AACTGGTTGA AATTCAGGAG TGAGAACAAT TGCTACCTCT ATGGTGTCTT CAATGGCTAT 180

GATGGCAACC GAGTCACCAA CTTTGTGGGC CAGAGGCTGT CTGCAGAATT GCTGCTGGGC 240

CAGCTGCACG CAGATCACAG TGATGCTGAT GTGCGCCGTG TTCTGCTTCA GGCTTTTGAT 300

GTGGTAGAAA GAAGTTTCTT GGAGTCTATT GATGATGCTT TGGCAGAGAA GGCCAGCCTG 360

CAGTCCCAGC TGCCAGAGGG TGTTCCTCAC CACCAGCTGC CTCCTCAATA CCAGAAGATC 420

GTGGAGAGAT TGAAGGTTGT AGAGCAGGAG ATCTCTGGAG GAGCCATGGC CATCGTGGCT 480

GTTGTTCTCA ACAATAAGCT CTATATTGCC AATGTTGGTA CCAATCGTGC ACTATTGTGT 540

AAGTCCACAG TGGATGGGCT GCAGGTGACT CAGCTAAACG TGGACCATAC TACAGAGAAT 600

GAGGATGAAC TTTTTCGCTT CTCTCAGCTG GGCTTGGATG CAGGGAAGAT AAAACAAGTG 660

GGAACTATCC GTGGGCAGGA AAGCACTCGG CGCATTGGAG ACTACAAAGT CAAATATGGC 720

TATACTGATA TTGAACTCCT CAGTGCTGCT AAATCTAAGC CTATTATAGC AGAGCCTGAA 780

ATCCATGGAG GGCACTCTCT GGATGGAGTG ACTGGCTTCT TGGTGCTTAT GTCTGAAGGG 840

CTCTACAAAG CTCTGGAAGC AGCTCATGGG CCTGGGCAGG CCAACCAGGA AATTGCAGCC 900

ATGATAGCCA CAGAGTTTGC CAAGCAGACG TCACTGGATG CCGTGGCCCA AGCTGTAGTG 960

GACCGGGTGA AACGGATCCA CTGTGACACT TTTGCCAGTG GTGGGGAGCG GTCCAAGTTC 1020

TGTCCCCGCC ATGAAGACAT GACCCTGCTT GTGAGAAATT TTGGCTATCC CTTGGGTGAG 1080

ATGAGTCAGC CCACGCTAAC ACCAACACAA GGGGGCCGTG TCTACCCAGT CTCTGTGCCA 1140

TATTCCAGCT CCCAAAGCAC GAGCAAAACG AGCGTCACGC TGTCTCTTGT CATGCCTTCC 1200

CAAGGCCAGA TGGTCAACGG TGCCCACAGC AGCTCATGGA TGAAGCCACC CCCACCCTCA 1260

CTAACCAAAG CCCCACTGTG A 1281

Domain Profile

S: 26    lkspekkdrlaffgvyDGhggsevakfcseklheilaeelesseseerkvkkalakaFls  85

         lk +++++  +++gv++G  g++v++f+ ++l+  l       + ++++v+++l +aF

Q: 43    LKFRSENN-CYLYGVFNGYDGNRVTNFVGQRLSAELLLGQLHADHSDADVRRVLLQAFDV  101

         45555555.69*********************97666555558999**************

S: 86    tdeel...................................kvleeksldidksGstavva  110

         +++ +                                   + l+ + +++ + G+ a va

Q: 102   VERSFlesiddalaekaslqsqlpegvphhqlppqyqkivERLKVV-EQEISGGAMAIVA  160

         ******************************9999998553333333.3444499******

S: 111   likdsklyvanvGdSravLcrng.k...avelssdHkpsredEleRieeag...gsvilk  163

         ++ ++kly+anvG  ra+Lc++  +   + +l +dH++++edEl R ++ g   g++ +

Q: 161   VVLNNKLYIANVGTNRALLCKSTvDglqVTQLNVDHTTENEDELFRFSQLGldaGKIKQV  220

         ********************9663366699*********************977777776

S: 164   dgaRvlGvLavsRalGdlylk..............pyvtpePevts.hrltsedefliLa  208

             + G  + +R +Gd+++k              + +++ePe++  h l+  + fl+L

Q: 221   G--TIRG-QESTRRIGDYKVKygytdiellsaaksKPIIAEPEIHGgHSLDGVTGFLVLM  277

         5..7778.489***********************999*******95488999999*****

S: 209   sDGlwdvvs........neeavslvrdvlekkeaeqeaakkLvkl  245

         s Gl++ ++        n+e+ +++     k+++++++a+ +v++

Q: 278   SEGLYKALEaahgpgqaNQEIAAMIATEFAKQTSLDAVAQAVVDR  322

         ******986333333335666666655555677777777777765

Domain Sequence
(FASTA)

LKFRSENNCY LYGVFNGYDG NRVTNFVGQR LSAELLLGQL HADHSDADVR RVLLQAFDVV 60

ERSFLESIDD ALAEKASLQS QLPEGVPHHQ LPPQYQKIVE RLKVVEQEIS GGAMAIVAVV 120

LNNKLYIANV GTNRALLCKS TVDGLQVTQL NVDHTTENED ELFRFSQLGL DAGKIKQVGT 180

IRGQESTRRI GDYKVKYGYT DIELLSAAKS KPIIAEPEIH GGHSLDGVTG FLVLMSEGLY 240

KALEAAHGPG QANQEIAAMI ATEFAKQTSL DAVAQAVVDR 280

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Danio rerio"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0003824	; F:catalytic activity
GO:0019209	; F:kinase activator activity
GO:0000185	; P:activation of MAPKKK activity
GO:0008152	; P:metabolic process
GO:0007179	; P:transforming growth factor beta receptor signaling pathway

KEGG

InterPros

IPR001932	; PP2C-like.
IPR015655	; Protein_Pase_2C.

Pfam

PF00481

; PP2C; 1.

SMARTs

SM00332

; PP2Cc; 1.

Prosites

Prints

Created Date

20-Feb-2013