EKS-MEG-00195

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-MEG-00195

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/CAMKL	304.3	4.7E-91	1	226	226

Status

Unreviewed

Ensembl Protein

ENSMGAP00000013591

UniProt Accession

G1NJQ6;

Protein Name

Protein Synonyms/Alias

Gene Name

NUAK1

Gene Synonyms/Alias

NUAK1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMGAG00000012894	ENSMGAP00000013591	ENSMGAT00000014503

Organism

Meleagris gallopavo

Functional Description

Protein Length

581

Protein Sequence
(FASTA)

VAIKSIRKDK IKDEQDMIHI RREIEIMSSL SHPHIITIYE VFENKDKIVI IMEYASKGEL 60

YDYISERRRL SERETRHFFR QIVSAVHYCH KNGVVHRDLK LENILLDDNF NIKIADFGLS 120

NLYHKDKFLQ TFCGSPLYAS PEIVNGRPYR GPEVDSWALG VLLYTLVYGT MPFDGFDHKN 180

LIRQISSGEY REPTQTSDAR GLIRWMLMVN PERRATIEDI ANHWWVNWGY KSSVCDCDAM 240

RDSESPLLAR FIDWHHRSTG LQPETDTKMK CLSKPKGPEV TLERQRSLKK SKKENDIAQS 300

IQEGGAENAS KPTSKRPKGI LKKRSNSEHR SHSAGFIEGV VSPVLPSAFK LEQELCRTGV 360

AIKSVVEGEV AGKYGTKQSS LMPKKGILKK TQQRESGYYS SPERSESSEL LDNNDETVNS 420

DTSPGVTEPS RNGSYSHTCR RKGILKHNGK YSTSSTESAL ISPDTPTLEA MEEVVLPGDA 480

LPRSYSRPSS VISDDSILSS DSFDFLDLQE NRPNRQRIRS CVSAENFLQI QDFEGLQNHP 540

RPQYLKRYRN RLGDSSFSLL TDMDDVTQVY KKALEICNKL N 581

Nucleotide Sequence
(FASTA)

GTTGCAATTA AATCCATTCG TAAGGACAAA ATTAAGGATG AGCAAGATAT GATTCACATC 60

AGACGGGAGA TTGAGATCAT GTCATCCCTC AGCCACCCTC ATATCATCAC CATATATGAA 120

GTGTTTGAAA ATAAAGATAA GATTGTGATC ATCATGGAGT ACGCAAGTAA GGGAGAGTTG 180

TATGATTATA TCAGTGAGAG GCGACGACTG AGCGAAAGAG AAACAAGACA CTTCTTCCGA 240

CAAATAGTCT CTGCTGTACA TTACTGCCAC AAGAATGGTG TGGTCCACAG GGACCTAAAA 300

TTGGAAAACA TCCTTCTTGA TGACAATTTT AATATTAAGA TTGCTGATTT TGGACTCTCC 360

AACCTTTATC ACAAAGACAA ATTTTTGCAG ACCTTTTGTG GAAGCCCACT GTATGCTTCC 420

CCTGAAATTG TGAATGGCCG ACCTTACAGA GGCCCCGAGG TTGACAGCTG GGCCCTTGGT 480

GTATTGCTTT ACACTCTGGT TTATGGAACC ATGCCCTTTG ATGGCTTTGA TCACAAAAAT 540

CTCATCAGGC AGATCAGCAG TGGAGAATAT CGTGAACCAA CACAGACCTC AGATGCTCGT 600

GGTCTCATCA GATGGATGTT GATGGTGAAT CCTGAACGCC GAGCAACCAT TGAAGACATT 660

GCCAATCACT GGTGGGTTAA CTGGGGCTAC AAGAGTAGTG TTTGTGACTG TGATGCCATG 720

AGGGACTCTG AGTCCCCATT GCTAGCAAGG TTCATTGATT GGCATCACCG CTCTACTGGC 780

CTCCAGCCAG AGACTGATAC AAAAATGAAG TGCCTTTCTA AGCCCAAAGG TCCCGAAGTC 840

ACACTAGAGA GACAAAGGTC TCTGAAAAAA TCAAAAAAAG AAAATGACAT TGCACAGTCC 900

ATCCAGGAAG GAGGAGCTGA AAATGCATCC AAACCCACTT CCAAAAGACC CAAAGGCATC 960

CTGAAGAAAA GGAGCAACAG TGAACATCGA TCTCACAGTG CAGGGTTCAT TGAAGGTGTG 1020

GTCAGCCCAG TGTTACCTTC TGCTTTTAAG TTGGAGCAGG AGTTGTGTAG GACTGGTGTA 1080

GCCATTAAAA GTGTTGTGGA GGGAGAGGTA GCTGGCAAAT ACGGCACTAA GCAGTCTTCA 1140

CTAATGCCAA AAAAAGGAAT CTTAAAGAAG ACTCAGCAGA GGGAGTCCGG CTATTACTCC 1200

TCTCCAGAAC GAAGCGAATC TTCGGAACTC TTGGACAATA ATGATGAAAC AGTAAACAGT 1260

GATACCTCTC CAGGGGTCAC AGAACCATCC AGAAATGGGT CTTACAGCCA TACCTGCAGG 1320

CGTAAGGGTA TCTTGAAACA TAATGGCAAG TATTCTACCA GCAGCACTGA ATCTGCTTTA 1380

ATTAGCCCTG ATACACCAAC CCTGGAGGCC ATGGAAGAAG TAGTCCTGCC TGGAGATGCA 1440

TTACCTCGAA GTTACAGTCG CCCTTCCAGC GTGATTAGTG ATGACAGTAT TTTGTCCAGT 1500

GACTCCTTTG ATTTTCTGGA TTTGCAAGAG AACAGGCCAA ACAGACAGAG GATACGGAGC 1560

TGTGTCTCTG CTGAAAATTT CCTACAGATC CAAGACTTCG AAGGACTTCA GAACCATCCA 1620

CGGCCACAGT ACCTAAAACG GTATCGCAAC CGTCTGGGGG ACAGCAGTTT TTCCCTTCTC 1680

ACAGACATGG ATGATGTGAC TCAGGTCTAC AAGAAAGCCC TAGAGATCTG CAACAAGCTC 1740

AACTAG 1746

Domain Profile

S: 27    vavKiikkkkl.seeslekikrEieilkklkhpniikllevietkkklylvleyasggeL  85

         va+K i+k+k+ +e+ + +i+rEiei+++l+hp+ii ++ev+e+k+k+++++eyas+geL

Q: 1     VAIKSIRKDKIkDEQDMIHIRREIEIMSSLSHPHIITIYEVFENKDKIVIIMEYASKGEL  60

         8*********95666677******************************************

S: 86    fdyieekgrlkekearklfkqlvsavkYlhskgivHrDlKpeNllldkkenikiaDFGla  145

         +dyi+e++rl+e+e+r++f+q+vsav+Y+h++g+vHrDlK+eN+lld++ nikiaDFGl+

Q: 61    YDYISERRRLSERETRHFFRQIVSAVHYCHKNGVVHRDLKLENILLDDNFNIKIADFGLS  120

         ************************************************************

S: 146   nlfkegklletfcGsppYaaPellkgkkYegpkvDvWslGvvLyalvtgklPfdeenlke  205

         nl++++k l+tfcGsp Ya+Pe+++g++Y+gp+vD W+lGv+Ly+lv+g++Pfd+ + k+

Q: 121   NLYHKDKFLQTFCGSPLYASPEIVNGRPYRGPEVDSWALGVLLYTLVYGTMPFDGFDHKN  180

         ************************************************************

S: 206   llekilkgkleipkklskelesLlrklLvvdpekRatieeilkhewl  252

         l ++i++g+++ p++ +++++ L+r +L+v+pe+Ratie+i +h w+

Q: 181   LIRQISSGEYREPTQ-TSDARGLIRWMLMVNPERRATIEDIANHWWV  226

         **************9.6689**************************6

Domain Sequence
(FASTA)

VAIKSIRKDK IKDEQDMIHI RREIEIMSSL SHPHIITIYE VFENKDKIVI IMEYASKGEL 60

YDYISERRRL SERETRHFFR QIVSAVHYCH KNGVVHRDLK LENILLDDNF NIKIADFGLS 120

NLYHKDKFLQ TFCGSPLYAS PEIVNGRPYR GPEVDSWALG VLLYTLVYGT MPFDGFDHKN 180

LIRQISSGEY REPTQTSDAR GLIRWMLMVN PERRATIEDI ANHWWV 226

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Danio rerio"; ?>Dasypus novemcinctus"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005737	; C:cytoplasm
GO:0005634	; C:nucleus
GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0030155	; P:regulation of cell adhesion
GO:2000772	; P:regulation of cellular senescence
GO:0035507	; P:regulation of myosin-light-chain-phosphatase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013