EPS-MEG-00045

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-MEG-00045

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPP/PP7	448.8	7.1E-135	125	450	326

Status

Unreviewed

Ensembl Protein

ENSMGAP00000015545

UniProt Accession

G1NPA0;

Protein Name

Serine/threonine-protein phosphatase

Protein Synonyms/Alias

Gene Name

PPEF1

Gene Synonyms/Alias

PPEF1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMGAG00000014672	ENSMGAP00000015545	ENSMGAT00000016502

Organism

Meleagris gallopavo

Functional Description

Protein Length

639

Protein Sequence
(FASTA)

MGCNASADYS KHKYNETAIK ATVLIQRWYR CKRAQLEVRR RYSLTIFESI EYADEQEQTQ 60

LSNFFTFMLE HRVHRGEGKE ENQKILKPQK VQKDSWFYYE KIDVPDSYRG PRLSFPLNIA 120

HAKALLNALK NRQLLHPRYV LQLLHETRRL LKEKPNITHV SVSYFKEITI CGDLHGNLDD 180

LLLVFHKNGL PSEINPYVFN GDFVDRGKNS MEILIILFVF LLIYPNDFHL NRGNHEDYIL 240

NMKYGFTKEV LKKYKVHGMT ILYHLRDIFS WLPLATLVNN KVLIVHGGIS DTTDLDSLNL 300

LERNKLKTLM KLPKLETDRK NQVKIQGIPL GYPELSQWSS HPELTEEERK QVLDILWSDP 360

KKQHGCNLNR RRGAGCCFGP DTTEQLLKKY NLKMLIRSHE FKLNGYDLTH DGKVITIFSA 420

SNYYEEGSNR GAYIRMNPDL VPRFVQYQVC TSTGKRKNWE RVKTIEQSAL QTLQERIFVH 480

KQKLMDTFAK YDCNNTGRIS VSDWAAVMES VLQLKLPWRT LKSRLVKTDP DGNVDYMSCF 540

YYMDTARPMH QVQPTLVETL CKYRKDLQVI FNIIDEDESG LISPDEFRKT WKIFSSYLGI 600

HSHDEAIDKL AQSIDYNKDG YIDFSEFLEA FHVVRKLEN 639

Nucleotide Sequence
(FASTA)

ATGGGGTGCA ACGCTTCTGC AGATTACAGT AAACACAAAT ATAATGAAAC AGCCATAAAA 60

GCTACTGTGT TAATCCAGAG ATGGTACCGC TGTAAAAGAG CCCAGCTAGA GGTCCGTCGC 120

CGCTATTCTC TCACTATCTT TGAGTCAATC GAATATGCTG ATGAGCAAGA GCAAACACAG 180

TTGTCCAACT TTTTCACATT CATGCTGGAG CACCGTGTTC ATCGTGGTGA AGGTAAGGAG 240

GAAAACCAAA AAATACTGAA ACCCCAAAAA GTGCAGAAAG ATTCTTGGTT TTATTATGAA 300

AAGATTGATG TTCCAGACTC CTATCGTGGA CCACGACTCT CATTTCCCCT TAATATTGCA 360

CATGCTAAGG CTCTTCTTAA TGCGCTCAAG AATCGACAGC TGCTTCATCC CCGCTATGTA 420

CTGCAGCTGT TACATGAGAC CAGGAGACTT CTCAAGGAGA AGCCAAATAT CACCCATGTT 480

TCAGTTTCCT ACTTCAAGGA GATAACCATC TGTGGAGACT TACATGGAAA TCTGGATGAT 540

CTTTTACTGG TATTCCATAA GAATGGTCTG CCTTCAGAAA TCAACCCTTA TGTCTTTAAT 600

GGCGATTTTG TTGACAGAGG AAAAAATTCT ATGGAAATAC TTATAATCCT ATTTGTTTTT 660

CTTCTTATCT ACCCGAATGA TTTTCACTTG AACAGAGGAA ACCATGAAGA CTACATCTTA 720

AACATGAAAT ATGGCTTCAC TAAAGAAGTT TTGAAGAAGT ATAAGGTCCA TGGCATGACA 780

ATTCTGTATC ATCTGCGAGA CATTTTCAGC TGGCTTCCCC TTGCCACTTT AGTTAATAAC 840

AAAGTGCTTA TAGTACATGG AGGAATTTCA GACACCACAG ATTTGGATTC CCTGAATTTA 900

CTTGAGAGAA ATAAGCTGAA AACATTGATG AAGCTACCAA AGTTAGAGAC AGACAGAAAG 960

AACCAAGTGA AAATACAAGG CATCCCACTG GGCTATCCTG AGCTTTCCCA ATGGAGTTCA 1020

CATCCAGAGC TCACCGAGGA GGAACGGAAA CAAGTCCTGG ACATTCTCTG GAGTGATCCA 1080

AAAAAACAAC ATGGCTGTAA TCTGAACCGG CGTCGAGGAG CAGGTTGTTG CTTTGGCCCT 1140

GACACTACTG AGCAGCTGCT TAAAAAGTAT AATCTGAAGA TGCTAATCAG GTCTCATGAA 1200

TTTAAGCTGA ACGGCTATGA CCTCACACAT GATGGGAAGG TTATCACTAT ATTTTCTGCT 1260

TCTAACTATT ATGAAGAGGG GAGCAACCGG GGAGCATACA TCCGAATGAA TCCTGATCTG 1320

GTTCCCCGTT TTGTACAGTA CCAAGTCTGC ACGAGCACAG GCAAACGGAA GAACTGGGAG 1380

AGGGTGAAAA CAATTGAACA GTCTGCTTTA CAAACCTTAC AAGAGAGGAT TTTTGTTCAC 1440

AAGCAAAAAC TCATGGATAC CTTTGCAAAG TATGACTGCA ACAACACAGG CAGGATTTCT 1500

GTCAGTGACT GGGCAGCAGT GATGGAGTCA GTCTTACAAC TCAAACTGCC CTGGAGGACA 1560

CTGAAGTCTC GGTTAGTGAA GACAGATCCA GATGGAAACG TTGACTACAT GTCATGTTTT 1620

TACTATATGG ACACAGCTCG TCCTATGCAT CAGGTTCAGC CAACTTTGGT GGAAACGCTG 1680

TGCAAATACA GAAAGGATCT GCAGGTGATC TTCAACATCA TAGATGAAGA TGAGTCAGGT 1740

CTGATTTCTC CTGATGAGTT CCGCAAGACC TGGAAAATCT TCAGTTCTTA CCTGGGAATT 1800

CATTCACACG ATGAAGCCAT TGACAAGTTA GCCCAGAGCA TAGACTACAA CAAAGATGGC 1860

TATATTGACT TCAGTGAATT TTTAGAGGCC TTTCATGTGG TTCGCAAACT AGAGAAC 1917

Domain Profile

S: 4     llevfkkkrilhakyvlevlfeakkvlkqlpnishvstavskevtvvGdlhGklddlllv  63

         ll+++k+++ lh++yvl++l+e+++ lk+ pni+hvs +  ke+t++GdlhG+lddlllv

Q: 125   LLNALKNRQLLHPRYVLQLLHETRRLLKEKPNITHVSVSYFKEITICGDLHGNLDDLLLV  184

         899*********************************************************

S: 64    lkknGlPsernpyvfnGdfvdrGkrglevllvllslflvfPnavylnrGnhedkvmnary  123

         ++knGlPse npyvfnGdfvdrGk+++e+l++l ++ l++Pn+ +lnrGnhed ++n++y

Q: 185   FHKNGLPSEINPYVFNGDFVDRGKNSMEILIILFVFLLIYPNDFHLNRGNHEDYILNMKY  244

         ************************************************************

S: 124   GfekevlskykrkgkrilrileevyewlPlgsivdsrvlvvhGGlsestsldllksverk  183

         Gf+kevl+kyk +g  il  l +++ wlPl+++v+++vl+vhGG+s++t+ld l+ +er+

Q: 245   GFTKEVLKKYKVHGMTILYHLRDIFSWLPLATLVNNKVLIVHGGISDTTDLDSLNLLERN  304

         ************************************************************

S: 184   krksvllpP.eessrd...........lgrldtdgepreslteteweqiidilwsdPrat  231

         k k+++  P +e++r+           +  l +  +++ +lte+e +q++dilwsdP+ +

Q: 305   KLKTLMKLPkLETDRKnqvkiqgiplgYPELSQW-SSHPELTEEERKQVLDILWSDPKKQ  363

         ****997662588888999999999554455444.44579********************

S: 232   nGlvPntlrGaGvyfGPdvtedflkkyelklvirsheckpegyeilhdgkvvtifsasny  291

         +G+  n  rGaG+ fGPd te++lkky+lk++irshe k +gy+++hdgkv+tifsasny

Q: 364   HGCNLNRRRGAGCCFGPDTTEQLLKKYNLKMLIRSHEFKLNGYDLTHDGKVITIFSASNY  423

         ************************************************************

S: 292   yeegsnkgayiklnsqltprfvqyiva  318

         yeegsn+gayi++n +l+prfvqy+v+

Q: 424   YEEGSNRGAYIRMNPDLVPRFVQYQVC  450

         ************************985

Domain Sequence
(FASTA)

LLNALKNRQL LHPRYVLQLL HETRRLLKEK PNITHVSVSY FKEITICGDL HGNLDDLLLV 60

FHKNGLPSEI NPYVFNGDFV DRGKNSMEIL IILFVFLLIY PNDFHLNRGN HEDYILNMKY 120

GFTKEVLKKY KVHGMTILYH LRDIFSWLPL ATLVNNKVLI VHGGISDTTD LDSLNLLERN 180

KLKTLMKLPK LETDRKNQVK IQGIPLGYPE LSQWSSHPEL TEEERKQVLD ILWSDPKKQH 240

GCNLNRRRGA GCCFGPDTTE QLLKKYNLKM LIRSHEFKLN GYDLTHDGKV ITIFSASNYY 300

EEGSNRGAYI RMNPDLVPRF VQYQVC 326

Keyword

Calcium; Complete proteome; Hydrolase; Iron; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Dipodomys ordii"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Macaca mulatta"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Tursiops truncatus"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005509	; F:calcium ion binding
GO:0004721	; F:phosphoprotein phosphatase activity

KEGG

InterPros

IPR011992	; EF-hand-like_dom.
IPR018247	; EF_Hand_1_Ca_BS.
IPR018249	; EF_HAND_2.
IPR002048	; EF_hand_Ca-bd.
IPR000048	; IQ_motif_EF-hand-BS.
IPR004843	; Metallo_PEstase_dom.
IPR013235	; PPP_dom.
IPR006186	; Ser/Thr-sp_prot-phosphatase.

Pfam

PF00149	; Metallophos; 1.
PF08321	; PPP5; 1.

SMARTs

SM00054	; EFh; 3.
SM00015	; IQ; 1.
SM00156	; PP2Ac; 1.

Prosites

PS00018	; EF_HAND_1; 3.
PS50222	; EF_HAND_2; 3.
PS00125	; SER_THR_PHOSPHATASE; 1.

Prints

PR00114

; STPHPHTASE.

Created Date

20-Feb-2013