EKS-MEG-00325

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-MEG-00325

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
STE/STE11	330.9	5.6E-99	596	859	264

Status

Unreviewed

Ensembl Protein

ENSMGAP00000016902

UniProt Accession

G1NRX9;

Protein Name

Protein Synonyms/Alias

Gene Name

YSK4

Gene Synonyms/Alias

YSK4;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMGAG00000015963	ENSMGAP00000016902	ENSMGAT00000017876

Organism

Meleagris gallopavo

Functional Description

Protein Length

863

Protein Sequence
(FASTA)

AMSEVTAKSQ SELVPVVHVT FSEQELPRKP CIAKHPARRR STVRSLPPHI SQSFNVLARK 60

DNDKSEIKLN KNKCSSRSKM SSKTRTAEGL VISDEISINH NTQKRNAKRQ IFPSLQLPCV 120

GSETFLKCQK KPPQHNKCNF LQSSQRVKKQ SSSCSCKNLV ISKKPVTPLS LQYAQSASEF 180

VQLKYSDMFK KINSNDKGPD VYEMFGTPVY SHVRELDHLE NSFYRDVCSA PPGGCTASTC 240

SSTCNKRRDS SRIRNTQKRT HSKPKKTKSV TKQKQKGLQA NNKIIELSGS NTEQDNVISS 300

GPDCQIQTSS SVTLFHGNTD HQLIFLEELS ESTKPSKILS NSKLSTIKEA SLEQSLDSQD 360

LSNHQIDASC SQDLLQLSNK VDIECAALRN NLITADQNIC VPQYRVDMNG CKSLESDQVS 420

FETLNQGEAL PFSDKQECQL LTNKLSHSWS YTPQNSILAN ELSQPPMIQT TNVTSPSFQT 480

SRNILSWAGN KDVTDELLCC LAAELLMLED KDINSSRTKY AGSKMQNTCT KEEGNMMNRD 540

GEIADNDLDE ASTKCWMKDE SSFKLKIYNE ESGLLNFEES TQVSGSNLNN KDTIMWTRGE 600

VLGKGAYGTV YCGLTNQGQL IAVKQVVLDT SDRLTTEKEY QKLHEEVDLL KTLKHVNIVT 660

YLGTCLEENI LSIFMEFVPG GSISSILSRF GPLPEIVLCK YTKQILEGVA YLHDNCVVHR 720

DIKGNNVMLM PNGIVKLIDF GCARRLAWVS LSGTHSEMLK SVHGTPYWMA PEVINESGYG 780

RKSDIWSVGC TVFEMATGKP PLASMDRVAA MFYIGAHRGL MPSLPDRFSG TAVDFVHACL 840

TRDQHERPSA LQLLDHPFMK GRQ 863

Nucleotide Sequence
(FASTA)

GCAATGTCAG AAGTGACTGC AAAAAGTCAA AGTGAGCTTG TTCCTGTTGT CCATGTTACT 60

TTCTCTGAAC AAGAACTACC TAGGAAACCA TGCATTGCTA AACATCCTGC CAGAAGAAGG 120

AGCACTGTTC GTAGCCTGCC TCCTCATATC AGTCAGAGCT TCAATGTTCT TGCTCGCAAA 180

GACAATGACA AAAGTGAGAT AAAGCTGAAT AAAAACAAAT GTTCATCAAG ATCTAAAATG 240

AGTAGCAAGA CAAGGACAGC TGAAGGGTTA GTTATTTCTG ATGAGATTTC CATAAATCAT 300

AATACACAAA AGAGGAATGC CAAGAGGCAG ATTTTTCCAT CTTTGCAACT GCCATGTGTG 360

GGTTCTGAGA CTTTCCTGAA GTGTCAAAAA AAACCACCTC AACACAACAA ATGTAATTTT 420

CTTCAGAGTT CTCAGAGAGT TAAAAAGCAA AGTTCTTCCT GCAGTTGCAA AAATCTAGTT 480

ATCTCAAAGA AACCTGTTAC TCCACTTTCT CTACAATATG CACAATCTGC TTCAGAGTTT 540

GTACAACTGA AATACAGTGA TATGTTCAAG AAAATAAATT CAAATGACAA AGGCCCAGAT 600

GTTTATGAAA TGTTTGGAAC TCCTGTCTAT TCCCACGTGC GTGAGCTTGA TCATCTTGAG 660

AACAGTTTTT ACAGAGATGT TTGTTCTGCT CCACCTGGGG GATGCACTGC TAGCACCTGC 720

AGTTCTACCT GCAATAAAAG AAGAGATAGC AGCCGAATAA GAAATACTCA AAAGAGAACA 780

CATTCTAAGC CAAAGAAGAC TAAATCTGTC ACTAAACAAA AGCAGAAAGG CTTACAAGCA 840

AACAATAAAA TTATTGAATT GAGTGGTAGC AACACAGAGC AAGATAATGT AATATCTTCT 900

GGTCCGGATT GTCAAATACA AACTTCAAGT AGTGTGACAT TGTTTCATGG AAACACAGAT 960

CATCAGCTTA TATTTTTAGA AGAGCTTTCA GAATCAACCA AGCCAAGCAA AATTCTTTCA 1020

AATTCAAAGT TATCAACTAT TAAAGAAGCC TCTTTGGAGC AGTCTCTAGA CAGTCAGGAT 1080

TTATCCAACC ATCAGATAGA TGCTTCCTGC AGCCAGGATC TTCTTCAACT CAGCAATAAA 1140

GTCGACATAG AATGTGCTGC TCTAAGAAAC AATTTAATAA CAGCAGACCA GAACATTTGT 1200

GTACCCCAGT ACAGAGTGGA TATGAATGGC TGCAAAAGCC TGGAATCAGA CCAGGTCTCC 1260

TTCGAGACTC TAAATCAGGG AGAAGCATTG CCCTTTTCAG ATAAACAGGA GTGTCAACTC 1320

CTTACAAACA AGTTAAGTCA CAGTTGGTCA TACACACCTC AGAACAGTAT TTTGGCAAAT 1380

GAACTCAGTC AGCCTCCAAT GATTCAGACA ACAAATGTTA CAAGCCCCAG TTTCCAAACA 1440

AGTCGAAACA TTTTGTCTTG GGCAGGTAAT AAGGATGTAA CCGATGAGTT GCTTTGTTGT 1500

CTGGCTGCAG AATTGCTAAT GCTCGAAGAT AAAGACATCA ACTCTTCAAG GACAAAATAT 1560

GCAGGTTCTA AAATGCAGAA TACCTGTACT AAAGAAGAAG GAAACATGAT GAACAGGGAT 1620

GGAGAAATAG CAGATAATGA TCTAGATGAA GCTTCAACAA AGTGTTGGAT GAAAGATGAG 1680

TCTTCATTTA AATTAAAAAT ATACAATGAA GAAAGTGGAC TGCTGAACTT TGAGGAGTCT 1740

ACTCAAGTAT CAGGAAGCAA TTTAAATAAC AAGGATACTA TCATGTGGAC AAGAGGTGAA 1800

GTCCTTGGAA AGGGAGCTTA TGGCACAGTA TACTGTGGTC TGACAAACCA AGGACAATTA 1860

ATAGCTGTAA AGCAGGTTGT TTTGGATACG TCAGATCGAC TGACTACAGA AAAGGAGTAC 1920

CAGAAGCTGC ATGAGGAAGT TGATCTTCTG AAGACATTGA AGCATGTCAA TATTGTAACT 1980

TACTTAGGAA CTTGTCTGGA AGAAAACATT TTAAGTATTT TCATGGAGTT TGTTCCTGGT 2040

GGCTCAATTT CCAGTATTCT TAGTCGTTTT GGTCCATTGC CAGAAATTGT CCTTTGTAAA 2100

TACACGAAAC AAATTCTAGA AGGGGTTGCA TATTTACATG ACAATTGTGT AGTACATAGA 2160

GATATCAAGG GCAATAATGT TATGCTCATG CCAAATGGAA TAGTAAAGCT AATTGACTTT 2220

GGCTGTGCCC GGCGTTTAGC TTGGGTCAGC CTCAGCGGCA CACACAGCGA GATGCTCAAG 2280

TCTGTGCATG GGACTCCATA TTGGATGGCA CCAGAAGTTA TCAATGAATC TGGATATGGG 2340

AGGAAATCAG ACATCTGGAG CGTTGGCTGC ACAGTGTTTG AGATGGCAAC AGGAAAACCA 2400

CCACTGGCTT CCATGGACAG GGTAGCAGCC ATGTTCTATA TTGGGGCTCA CAGGGGACTG 2460

ATGCCTTCCC TACCTGATCG ATTCTCTGGA ACTGCAGTGG ACTTTGTGCA TGCATGCTTA 2520

ACCAGAGATC AACATGAACG CCCTTCTGCT CTGCAGTTGT TGGACCATCC CTTTATGAAA 2580

GGAAGACAGT GA 2592

Domain Profile

S: 1     wqkrevigkGsfgsvyaaldvdtgellavKeveikp.ekksekkevkalkeEikllkelk  59

         w+++ev+gkG++g+vy++l+ ++g+l+avK+v +++ ++ +++ke+++l+eE++llk+lk

Q: 596   WTRGEVLGKGAYGTVYCGLT-NQGQLIAVKQVVLDTsDRLTTEKEYQKLHEEVDLLKTLK  654

         899***************98.89*********998515567778****************

S: 60    HenivkyyGveveeeelkiflEyvegGslssllekygkleesvikkytkqileglayLHe  119

         H niv+y+G++ ee+ l+if+E+v+gGs+ss+l+++g+l e v++kytkqileg+ayLH+

Q: 655   HVNIVTYLGTCLEENILSIFMEFVPGGSISSILSRFGPLPEIVLCKYTKQILEGVAYLHD  714

         ************************************************************

S: 120   kkivHRDiKgaNilldssgvvklsDFGaskrlaelntkaae...lesltGtlaymaPEvi  176

         +++vHRDiKg+N++l+ +g+vkl DFG+++rla+++ + ++   l+s++Gt+++maPEvi

Q: 715   NCVVHRDIKGNNVMLMPNGIVKLIDFGCARRLAWVSLSGTHsemLKSVHGTPYWMAPEVI  774

         **********************************999888777789**************

S: 177   kkkekgygrkaDiWslgcvviemltgkrPfaeldeelaimfkvgakk.tkPeipeklsee  235

         +++  gygrk+DiWs+gc+v+em+tgk+P a++ +++a+mf +ga++  +P++p+++s +

Q: 775   NES--GYGRKSDIWSVGCTVFEMATGKPPLASM-DRVAAMFYIGAHRgLMPSLPDRFSGT  831

         988..****************************.9*********99979***********

S: 236   gkdflekcleldpkkrpsaeeLLkhefl  263

         + df++ cl++d+++rpsa +LL+h+f+

Q: 832   AVDFVHACLTRDQHERPSALQLLDHPFM  859

         **************************96

Domain Sequence
(FASTA)

WTRGEVLGKG AYGTVYCGLT NQGQLIAVKQ VVLDTSDRLT TEKEYQKLHE EVDLLKTLKH 60

VNIVTYLGTC LEENILSIFM EFVPGGSISS ILSRFGPLPE IVLCKYTKQI LEGVAYLHDN 120

CVVHRDIKGN NVMLMPNGIV KLIDFGCARR LAWVSLSGTH SEMLKSVHGT PYWMAPEVIN 180

ESGYGRKSDI WSVGCTVFEM ATGKPPLASM DRVAAMFYIG AHRGLMPSLP DRFSGTAVDF 240

VHACLTRDQH ERPSALQLLD HPFM 264

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013