EKS-MIM-00009

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-MIM-00009

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/CAMKL	350.5	3.7E-105	23	277	255

Status

Unreviewed

Ensembl Protein

ENSMICP00000000500

Gene Name

SIK1

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMICG00000000552	ENSMICP00000000500	ENSMICT00000000554

Organism

Microcebus murinus

Protein Length

778

Protein Sequence
(FASTA)

MVIMSEFGAA PAGQQKPLRV GFYDVERTLG KGNFAVVKLA RHRVTKTQVA IKIIDKTRLD 60

SSNLEKIYRE VQLMKLLNHP HIIKLYQVME TKDMLYIVTE FAKNGEMFDY LTSNGHLSEN 120

EARKKFWQIL SAVEYCHSHH VVHRDLKTEN LLLDGNMDIK LAGKEDFGFG NFYKPGEPLS 180

TWCGSPPYAA PEVFEGKEYE GPQLDIWSLG VVLYVLVCGS LPFDGPNLPT LRQRVLEGRF 240

RIPFFMSQDC ESLIRRMLVV DPAKRITLAQ IRQHRWMQAA PSLLRQPPLA CPAHGCSASP 300

GDPDERVLGI MQTLGIDRQR TVESLQSRSY NHFAAIYYLL LERLQEHRNT PCARPGPARP 360

HRPRSSDLSG FEVPQEGLPA DPFRSVLLCP QPPALAQSVL QAEMDCDLHS SLQPLFFPLD 420

ANCNAVFRHR PVSPSSLLDT AISEEARPGP GLEEEREAQE ALPSSTGRRH TLAEVSTRFS 480

PLTPPCIVVS PSAVASPAEG ASSDSCLTFS ASDGPAALSG GLASQGLLGT CSPVRLASPF 540

LGSQSATPVL QAQGDLGGAA LLPVSFQEGR RASDTSLTQG LKAFRQQLRK TTRTKGFLGL 600

NKIKGLARQV CQSPSSRAAR GGLSPFHTPA QSPGLHGGAA SGREGRSLLE EVLQQQRLLQ 660

LQHHPATPPP CQQAPQAYAL GPCDGPGAAP LPSALLAAGL PLLPAPLLQA SVSPVASAAR 720

LLDAHLHISA GPVALPAAPP LPRLAVLAPG CDPTGLPRGD CEMEDLTAGQ RGTFVLVQ 778

Nucleotide Sequence
(FASTA)

ATGGTGATCA TGTCGGAGTT CGGCGCGGCG CCCGCGGGCC AGCAGAAGCC CCTCCGGGTG 60

GGCTTCTACG ACGTGGAGCG GACGCTGGGC AAAGGCAACT TCGCGGTGGT GAAGCTGGCG 120

CGGCACCGGG TCACCAAGAC GCAGGTTGCC ATAAAAATAA TCGATAAAAC ACGATTAGAT 180

TCAAGCAATT TGGAGAAAAT ATATCGTGAG GTTCAGCTCA TGAAGCTTCT GAATCACCCT 240

CATATTATAA AGCTTTACCA GGTTATGGAA ACAAAGGACA TGCTTTACAT TGTCACTGAA 300

TTTGCAAAAA ATGGAGAAAT GTTTGACTAT CTGACGTCCA ACGGGCACCT GAGCGAGAAC 360

GAAGCGCGGA AGAAGTTCTG GCAGATTCTG TCGGCCGTGG AGTACTGCCA CAGCCACCAT 420

GTCGTGCACC GGGACCTCAA GACCGAGAAC CTTCTGCTGG ACGGCAACAT GGACATCAAG 480

TTGGCAGGCA AGGAGGACTT TGGATTTGGG AATTTCTACA AGCCAGGAGA GCCTCTCTCC 540

ACGTGGTGTG GGAGCCCCCC GTACGCAGCC CCAGAGGTCT TCGAGGGGAA GGAGTACGAA 600

GGCCCCCAGC TGGACATCTG GAGCCTCGGC GTCGTGCTGT ACGTCCTCGT CTGCGGGTCC 660

CTCCCCTTTG ACGGGCCCAA CCTGCCGACT CTGAGACAGC GGGTGCTGGA GGGCCGGTTC 720

CGCATCCCCT TCTTCATGTC CCAAGACTGC GAGAGCCTGA TCCGCCGCAT GCTGGTGGTG 780

GACCCCGCCA AGCGCATCAC CCTGGCGCAG ATCCGGCAGC ACAGGTGGAT GCAGGCCGCC 840

CCCAGCCTGC TGCGGCAGCC CCCGCTCGCC TGCCCTGCGC ACGGCTGCAG CGCCAGCCCC 900

GGCGACCCCG ACGAGCGGGT GCTGGGCATC ATGCAGACTC TCGGCATCGA CCGGCAGCGG 960

ACCGTGGAGT CCCTGCAGAG CCGCAGCTAC AACCACTTTG CCGCCATCTA TTACCTGCTC 1020

CTCGAGCGGC TCCAGGAGCA CCGGAACACC CCGTGCGCCC GCCCCGGGCC CGCCCGGCCA 1080

CACCGGCCCA GGAGCTCCGA CCTCAGCGGT TTCGAGGTGC CTCAGGAAGG CCTGCCTGCC 1140

GACCCCTTCC GCTCTGTCCT GCTGTGCCCG CAGCCCCCCG CCTTGGCGCA GTCCGTCCTG 1200

CAGGCTGAGA TGGACTGCGA CCTCCACAGC TCGCTCCAGC CCTTGTTCTT CCCGTTGGAC 1260

GCCAACTGCA ACGCGGTGTT CCGGCACCGC CCGGTCTCCC CCAGCAGCCT GCTGGACACG 1320

GCCATCAGCG AGGAGGCCCG GCCGGGCCCG GGGCTGGAGG AGGAGCGGGA GGCCCAGGAG 1380

GCCCTGCCCA GCAGCACGGG CCGGCGGCAC ACCCTGGCCG AGGTCTCCAC CCGCTTCTCC 1440

CCCCTCACCC CTCCGTGCAT CGTCGTCTCC CCGTCAGCCG TGGCAAGCCC TGCGGAAGGA 1500

GCCAGCTCCG ACAGCTGTCT GACCTTCTCC GCCAGCGATG GCCCTGCGGC GCTCAGTGGT 1560

GGCCTGGCCT CTCAGGGGCT GTTGGGCACC TGCTCCCCGG TCAGACTGGC CTCACCGTTC 1620

CTGGGCTCGC AGTCCGCCAC CCCTGTGCTG CAGGCTCAGG GCGACCTGGG AGGAGCCGCC 1680

CTGCTCCCTG TCAGCTTCCA GGAGGGCCGC AGGGCGTCGG ACACTTCGCT GACCCAGGGG 1740

CTCAAAGCCT TCCGGCAGCA GCTGAGGAAG ACCACGAGGA CCAAGGGGTT TCTGGGGCTG 1800

AACAAGATCA AGGGCTTGGC TCGCCAGGTG TGCCAGTCCC CCTCCAGCCG GGCTGCCAGG 1860

GGAGGCCTGA GCCCCTTCCA CACCCCTGCT CAGAGCCCGG GCCTGCACGG CGGCGCGGCT 1920

AGCGGCCGGG AGGGCCGGAG CCTGCTGGAA GAGGTGCTGC AGCAGCAGAG GCTGCTCCAG 1980

TTACAGCACC ACCCGGCCAC CCCGCCCCCC TGCCAGCAGG CCCCCCAGGC CTACGCGCTC 2040

GGCCCCTGCG ACGGCCCCGG GGCCGCCCCG CTCCCCAGCG CCCTCCTTGC CGCGGGGCTC 2100

CCGCTGCTGC CGGCCCCCCT CCTGCAGGCC AGTGTCTCCC CAGTGGCCTC GGCGGCGCGG 2160

CTGCTGGACG CCCATCTGCA CATCAGTGCT GGCCCGGTCG CCCTCCCGGC CGCGCCCCCG 2220

CTGCCGCGCC TGGCCGTGCT GGCCCCGGGC TGCGACCCCA CGGGGCTGCC GCGGGGGGAC 2280

TGCGAGATGG AGGACCTGAC GGCCGGCCAG CGGGGGACGT TCGTCCTGGT GCAGTGA 2337

Domain Profile

S: 1     ykllktlGegsfgkVklakhketkekvavKiikkkklseeslekikrEieilkklkhpni  60

         y++ +tlG+g+f+ Vkla+h+ tk++va+Kii+k++l++++leki+rE++++k l+hp+i

Q: 23    YDVERTLGKGNFAVVKLARHRVTKTQVAIKIIDKTRLDSSNLEKIYREVQLMKLLNHPHI  82

         899*********************************************************

S: 61    ikllevietkkklylvleyasggeLfdyieekgrlkekearklfkqlvsavkYlhskgiv  120

         ikl++v+etk++ly+v+e+a++ge+fdy++++g+l+e+eark f q++sav+Y+hs+++v

Q: 83    IKLYQVMETKDMLYIVTEFAKNGEMFDYLTSNGHLSENEARKKFWQILSAVEYCHSHHVV  142

         ************************************************************

S: 121   HrDlKpeNllldkkenikia...DFGlanlfkegklletfcGsppYaaPellkgkkYegp  177

         HrDlK+eNllld +++ik+a   DFG++n++k+g+ l+t+cGsppYaaPe+++gk+Yegp

Q: 143   HRDLKTENLLLDGNMDIKLAgkeDFGFGNFYKPGEPLSTWCGSPPYAAPEVFEGKEYEGP  202

         *******************8888*************************************

S: 178   kvDvWslGvvLyalvtgklPfdeenlkellekilkgkleipkklskelesLlrklLvvdp  237

         ++D+WslGvvLy+lv+g+lPfd++nl +l++++l+g+++ip+ +s+++esL+r++Lvvdp

Q: 203   QLDIWSLGVVLYVLVCGSLPFDGPNLPTLRQRVLEGRFRIPFFMSQDCESLIRRMLVVDP  262

         ************************************************************

S: 238   ekRatieeilkhewl  252

         +kR+t+ +i++h+w+

Q: 263   AKRITLAQIRQHRWM  277

         **************8

Domain Sequence
(FASTA)

YDVERTLGKG NFAVVKLARH RVTKTQVAIK IIDKTRLDSS NLEKIYREVQ LMKLLNHPHI 60

IKLYQVMETK DMLYIVTEFA KNGEMFDYLT SNGHLSENEA RKKFWQILSA VEYCHSHHVV 120

HRDLKTENLL LDGNMDIKLA GKEDFGFGNF YKPGEPLSTW CGSPPYAAPE VFEGKEYEGP 180

QLDIWSLGVV LYVLVCGSLP FDGPNLPTLR QRVLEGRFRI PFFMSQDCES LIRRMLVVDP 240

AKRITLAQIR QHRWM 255

Keyword

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>