EKS-MIM-00056

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-MIM-00056

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
STE/STE11	370.6	4.2E-111	391	650	260

Status

Unreviewed

Ensembl Protein

ENSMICP00000003490

Gene Name

MAP3K3

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMICG00000003825	ENSMICP00000003490	ENSMICT00000003827

Organism

Microcebus murinus

Protein Length

655

Protein Sequence
(FASTA)

EQEALNSIMK DLVALKMNRR APVPGYETMK NKDPGHPNRQ KKNSSSSSAL LNSPTVTTSS 60

CAGASEKKKF LSDVRIKFEH SGERRIIAFS RPVRYEDVEH KVTTVFGQPL DLHYMNNELS 120

ILLKNQDDLD KAIDILDRSS SMKSLRILLL SQDGNHNSSS PHSGVSRQVR IKASQSAGDI 180

NTVYQPPEPR SRHLSVSSQN PGRSSPPPGY VPERQQHIAR QGSYTSINSE GEFIPETSEQ 240

CMLDPLSSAE NSLSGSCQSL DRSADSPSFR KSRMSRAQSF PDNRQEYSDR ETQLYDKGVK 300

GGTYPRRYHV SVHHKDYNDG RRTFPRIRRH QGNLFTLVPS SRSLSTNGEN MGLAVQYLDP 360

RGRLRSADSE NALSVQERNV PTKSPSAPIN WRRGKLLGQG AFGRVYLCYD VDTGRELASK 420

QVQFDPDSPE TSKEVSALEC EIQLLKNLQH ERIVQYYGCL RDRAEKTLTI FMEYMPGGSV 480

KDQLKAYGAL TESVTRKYTR QILEGMSYLH SNMIVHRDIK GANILRDSAG NVKLGDFGAS 540

KRLQTICMSG TGMRSVTGTP YWMSPEVISG EGYGRKADVW SLGCTVVEML TEKPPWAEYE 600

AMAAIFKIAT QPTNPQLPSH ISEHGRDFLR RIFVEARQRP SAEELLTHHF AQLVY 655

Nucleotide Sequence
(FASTA)

GAGCAGGAGG CACTGAACTC GATCATGAAG GATCTTGTGG CCCTCAAGAT GAACCGACGT 60

GCCCCGGTGC CTGGATATGA GACCATGAAG AACAAAGACC CGGGTCACCC AAATAGGCAG 120

AAGAAAAACA GCAGCAGCAG CTCAGCCCTT CTGAACAGCC CCACAGTAAC AACAAGCTCA 180

TGTGCAGGGG CCAGTGAGAA AAAGAAATTT TTGAGTGACG TCAGAATCAA GTTTGAGCAC 240

AGCGGGGAGA GGCGAATTAT AGCATTCAGC CGGCCTGTGA GGTATGAAGA TGTAGAGCAC 300

AAGGTGACAA CAGTATTTGG GCAACCTCTT GATCTACATT ACATGAACAA TGAGCTCTCC 360

ATCTTGCTGA AAAACCAAGA TGATCTTGAT AAAGCAATTG ACATTTTGGA TAGAAGCTCA 420

AGCATGAAAA GCCTTAGGAT ATTGCTGCTG TCCCAGGATG GAAACCATAA CAGTTCCTCT 480

CCCCACTCTG GGGTGTCCAG GCAGGTGCGG ATCAAGGCTT CCCAGTCTGC AGGGGATATA 540

AATACCGTCT ACCAGCCCCC TGAGCCCAGA AGCAGGCATC TCTCTGTCAG CTCCCAGAAC 600

CCAGGCCGAA GCTCACCTCC CCCTGGTTAT GTCCCTGAAC GGCAGCAGCA CATTGCCCGG 660

CAGGGGTCCT ACACCAGCAT CAACAGTGAG GGGGAGTTCA TTCCAGAGAC CAGCGAGCAG 720

TGCATGCTGG ATCCCCTGAG CAGTGCAGAA AACTCCTTGT CGGGAAGCTG CCAATCGTTG 780

GACAGGTCAG CAGACAGCCC TTCCTTCCGG AAATCACGCA TGTCCCGAGC CCAGAGCTTC 840

CCTGACAACA GACAGGAGTA CTCAGATCGG GAAACTCAGC TGTATGACAA AGGGGTCAAA 900

GGTGGAACTT ACCCCCGGCG CTACCATGTG TCTGTGCACC ACAAGGACTA CAACGATGGC 960

AGAAGAACAT TTCCCCGAAT ACGGCGTCAT CAAGGCAACC TGTTCACCCT GGTGCCGTCC 1020

AGCCGCTCCC TGAGCACGAA TGGCGAGAAC ATGGGTCTGG CTGTGCAATA CCTGGACCCC 1080

CGTGGGCGCC TGCGGAGTGC AGACAGCGAG AACGCCCTCT CTGTGCAGGA GAGGAATGTG 1140

CCAACCAAGT CTCCTAGTGC CCCCATCAAC TGGCGCCGGG GGAAGCTCCT GGGTCAGGGT 1200

GCCTTCGGCA GGGTCTATTT GTGCTATGAT GTGGACACAG GACGAGAACT TGCTTCCAAG 1260

CAGGTCCAGT TTGACCCAGA TAGTCCTGAG ACAAGCAAGG AGGTGAGTGC TCTGGAGTGT 1320

GAGATCCAGT TGCTGAAGAA CTTGCAGCAT GAGCGCATCG TGCAGTATTA TGGCTGTCTG 1380

CGGGACCGTG CGGAGAAGAC CCTGACCATC TTCATGGAGT ACATGCCAGG GGGCTCCGTG 1440

AAGGACCAGT TGAAGGCCTA TGGAGCCCTG ACAGAGAGTG TGACCCGGAA GTATACCCGG 1500

CAAATCCTGG AGGGCATGTC CTACCTGCAC AGCAACATGA TTGTTCACCG GGACATCAAG 1560

GGAGCCAATA TCCTCCGAGA CTCTGCTGGG AATGTGAAGC TGGGGGACTT TGGGGCCAGC 1620

AAACGCCTAC AGACCATCTG CATGTCGGGG ACAGGCATGC GCTCAGTCAC CGGCACACCC 1680

TATTGGATGA GCCCTGAGGT GATCAGTGGC GAGGGCTATG GAAGGAAGGC AGACGTGTGG 1740

AGCCTGGGCT GCACTGTGGT GGAGATGCTG ACAGAGAAAC CACCTTGGGC AGAGTATGAA 1800

GCTATGGCCG CCATTTTCAA GATTGCCACC CAGCCCACCA ATCCTCAGCT GCCTTCCCAC 1860

ATCTCTGAAC ATGGCCGGGA CTTCCTGAGG CGCATTTTTG TGGAGGCTCG CCAGAGACCT 1920

TCAGCTGAGG AGCTGCTCAC ACACCACTTT GCACAGCTCG TGTACTGA 1968

Domain Profile

S: 1     wqkrevigkGsfgsvyaaldvdtgellavKeveikpekksekkevkalkeEikllkelkH  60

         w++++++g+G+fg+vy+++dvdtg+ la K+v+++p++ +++kev+al++Ei+llk+l+H

Q: 391   WRRGKLLGQGAFGRVYLCYDVDTGRELASKQVQFDPDSPETSKEVSALECEIQLLKNLQH  450

         899*********************************************************

S: 61    enivkyyGv..eveeeelkiflEyvegGslssllekygkleesvikkytkqileglayLH  118

         e+iv+yyG+  ++ e++l+if+Ey++gGs++++l++yg+l+esv++kyt+qileg++yLH

Q: 451   ERIVQYYGClrDRAEKTLTIFMEYMPGGSVKDQLKAYGALTESVTRKYTRQILEGMSYLH  510

         *********77778999*******************************************

S: 119   ekkivHRDiKgaNilldssgvvklsDFGaskrlaelntkaaelesltGtlaymaPEvikk  178

         +++ivHRDiKgaNil ds+g+vkl+DFGaskrl++++++ + ++s+tGt+++m+PEvi++

Q: 511   SNMIVHRDIKGANILRDSAGNVKLGDFGASKRLQTICMSGTGMRSVTGTPYWMSPEVISG  570

         **********************************************************99

S: 179   kekgygrkaDiWslgcvviemltgkrPfaeldeelaimfkvgakktkPeipeklseegkd  238

         +  gygrkaD+Wslgc+v+emlt+k+P+ae+ e++a++fk++++ t+P++p+++se+g+d

Q: 571   E--GYGRKADVWSLGCTVVEMLTEKPPWAEY-EAMAAIFKIATQPTNPQLPSHISEHGRD  627

         8..****************************.9***************************

S: 239   flekcleldpkkrpsaeeLLkhef  262

         fl++++ +++++rpsaeeLL+h+f

Q: 628   FLRRIF-VEARQRPSAEELLTHHF  650

         ******.8999***********99

Domain Sequence
(FASTA)

WRRGKLLGQG AFGRVYLCYD VDTGRELASK QVQFDPDSPE TSKEVSALEC EIQLLKNLQH 60

ERIVQYYGCL RDRAEKTLTI FMEYMPGGSV KDQLKAYGAL TESVTRKYTR QILEGMSYLH 120

SNMIVHRDIK GANILRDSAG NVKLGDFGAS KRLQTICMSG TGMRSVTGTP YWMSPEVISG 180

EGYGRKADVW SLGCTVVEML TEKPPWAEYE AMAAIFKIAT QPTNPQLPSH ISEHGRDFLR 240

RIFVEARQRP SAEELLTHHF 260

Keyword

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>