EKS-MIM-00029

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-MIM-00029

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDK	387.3	3.1E-116	4	288	285

Status

Unreviewed

Ensembl Protein

ENSMICP00000004322

Gene Name

CDK5

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMICG00000004746	ENSMICP00000004322	ENSMICT00000004743

Organism

Microcebus murinus

Protein Length

294

Protein Sequence
(FASTA)

MQKYEKLEKI GEGTYGTVFK AKNRETHEIV ALKRVRLDDD DEGVPSSALR EICLLKELKH 60

KNIVRLHDVL HSDKKLTLVF EFCDQDLKKY FDSCNGDLDP EIVKSFLFQL LKGLGFCHSR 120

NVLHRDLKPQ NLLINRNGEL KLADFGLARA FGIPVRCYSA EVVTLWYRPP DVLFGAKLYS 180

TSIDMWSAGC IFAELANAGR PLFPGNDVDD QLILDPVDTL LGTPTEEQWP SMTKLPDYKP 240

YPMYPATTSL VNVVPKLNAT GRDLLQNLLK CNPVQRISAE EALQHPYFSD FCPP 294

Nucleotide Sequence
(FASTA)

ATGCAGAAAT ACGAGAAACT GGAGAAGATT GGAGAAGGCA CCTACGGAAC CGTGTTCAAG 60

GCCAAAAACC GGGAGACTCA TGAGATCGTG GCTCTGAAAC GGGTGAGGCT GGATGACGAT 120

GATGAGGGAG TGCCAAGTTC CGCCCTCCGG GAGATCTGCC TGCTCAAGGA GCTGAAGCAC 180

AAGAACATCG TCAGGCTTCA TGACGTCCTG CATAGTGACA AGAAGCTGAC TTTGGTTTTT 240

GAATTCTGTG ACCAGGACCT GAAGAAGTAC TTTGACAGTT GCAATGGTGA TCTCGATCCT 300

GAGATAGTGA AGTCATTCCT CTTCCAGCTG CTAAAAGGCC TGGGATTCTG TCACAGCCGC 360

AACGTGCTGC ACAGGGACCT GAAGCCCCAG AACCTACTAA TAAACAGGAA CGGGGAGCTG 420

AAGTTGGCTG ACTTCGGCCT TGCTCGAGCC TTCGGGATCC CCGTTCGCTG TTACTCAGCC 480

GAGGTGGTCA CGCTGTGGTA CCGCCCCCCG GATGTCCTCT TTGGGGCCAA GCTGTACTCC 540

ACGTCCATCG ACATGTGGTC AGCCGGCTGC ATCTTCGCAG AGCTGGCCAA CGCTGGGCGG 600

CCTCTTTTCC CTGGCAACGA TGTTGATGAC CAACTGATCC TTGACCCCGT GGACACGCTG 660

CTGGGGACGC CGACTGAGGA GCAGTGGCCC TCCATGACCA AGCTGCCTGA CTATAAGCCC 720

TACCCAATGT ACCCAGCCAC GACATCCCTG GTGAATGTGG TGCCCAAGCT CAATGCCACA 780

GGGAGGGACC TGCTGCAGAA CCTTCTGAAG TGTAACCCTG TGCAGCGCAT CTCAGCAGAA 840

GAGGCCCTGC AGCACCCATA CTTCTCTGAC TTCTGTCCCC CCTAG 885

Domain Profile

S: 1     yeklekigeGtygkvykakdketgevvAlKkirlekekegvpitalrEisllkelkhkni  60

         yeklekigeGtyg+v+kak++et+e+vAlK++rl++++egvp++alrEi llkelkhkni

Q: 4     YEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKHKNI  63

         99**********************************************************

S: 61    vkLlevvakdkkklyLvfefleqdLkkllkkkkkkklsleevkslllqlleglaylHsnk  120

         v+L++v++ ++kkl+Lvfef++qdLkk++++++  +l++e vks+l+qll+gl ++Hs++

Q: 64    VRLHDVLH-SDKKLTLVFEFCDQDLKKYFDSCNG-DLDPEIVKSFLFQLLKGLGFCHSRN  121

         ********.99***********************.*************************

S: 121   ilHRDlKpqNlLiskegklklaDfGlarafssplktytkevvTlwYraPelLlgakeYst  180

         +lHRDlKpqNlLi+++g+lklaDfGlaraf+ p++ y+ evvTlwYr+P++L+gak Yst

Q: 122   VLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKLYST  181

         ************************************************************

S: 181   avDiWsvgcilaellt.rkplfqgkseidql..erifkllgtpsekvwpevsklpeykks  237

         ++D+Ws+gci+ael++  +plf+g++  dql  + + +llgtp+e++wp+++klp+yk

Q: 182   SIDMWSAGCIFAELANaGRPLFPGNDVDDQLilDPVDTLLGTPTEEQWPSMTKLPDYK-P  240

         **************97369********99963378***********************.5

S: 238   fpkkkkk.klkekvkklkekaldllekllaldpkkRisakealqhkyf  284

         +p ++++ +l ++v+kl+ +++dll++ll+++p +Risa+ealqh+yf

Q: 241   YPMYPATtSLVNVVPKLNATGRDLLQNLLKCNPVQRISAEEALQHPYF  288

         555555559**************************************9

Domain Sequence
(FASTA)

YEKLEKIGEG TYGTVFKAKN RETHEIVALK RVRLDDDDEG VPSSALREIC LLKELKHKNI 60

VRLHDVLHSD KKLTLVFEFC DQDLKKYFDS CNGDLDPEIV KSFLFQLLKG LGFCHSRNVL 120

HRDLKPQNLL INRNGELKLA DFGLARAFGI PVRCYSAEVV TLWYRPPDVL FGAKLYSTSI 180

DMWSAGCIFA ELANAGRPLF PGNDVDDQLI LDPVDTLLGT PTEEQWPSMT KLPDYKPYPM 240

YPATTSLVNV VPKLNATGRD LLQNLLKCNP VQRISAEEAL QHPYF 285

Keyword

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>