EKS-MIM-00027

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-MIM-00027

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/IKK	436.1	4.5E-131	15	289	275

Status

Unreviewed

Ensembl Protein

ENSMICP00000006011

Gene Name

IKBKB

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMICG00000006581	ENSMICP00000006011	ENSMICT00000006582

Organism

Microcebus murinus

Protein Length

704

Protein Sequence
(FASTA)

MSWSPSLPTQ TCGAWEMKER LGTGGFGNVI RWHNQETGEQ IAIKQCRQEL SPRNRERWCL 60

EIQIMRRLNH PNVVAARDVP EGMQNLAPND LPLLAMEYCQ GGDLRKYLNQ FENCCGLREG 120

AILTLLSDIA SALRYLHENR IIHRDLKPEN IVLQQGEQRL IHKIIDLGYA KELDQGSLCT 180

SFVGTLQYLA PELLEQQKYT VTVDYWSFGT LAFECITGFR PFLPNWQPVQ WHSKVRQKSE 240

MDIVVSEDLN GAVKFSSSLP YPNNLNSVLA QRLKKWLQLM LMWHPRQRGT DPTYGPNGCF 300

KALDDILNLK LVHILNMVTG TIHTYPVTED ESLQSLKARI QQDTGIPEKD QELLQEAGLA 360

LIPEKPATQC ISDSKLNEGR TLDMDLVFLF DNSKVNYETQ ISPRPQPESV SCILQEPKRN 420

LSFFQLRKVW GQVWHSIQTL KEDCNRLQQG QRAAMMNLLR NNSCLSKMKN SMASMSQQLK 480

AKLDFFKTSI QIDLEKYSEQ TEFGITSDKL LLAWREMEQA VELCGRENEV KHLVERMMAL 540

QTDIVDLQRS PMGRKPGGTL DDLEEQAREL YRRLREKPRD QRTDGDSQEM VRLLLQAIQG 600

FEKKVRVIYT QLSKTVVCKQ KALELLPKVE EVVELMNEDE KTVVRLQEKR QKELWNLLKI 660

ACSKVRGPVS GSPDSMNASR LSHPGQLMSQ PSAAPSSLPE SAKK 704

Nucleotide Sequence
(FASTA)

ATGAGCTGGT CACCGTCCCT GCCAACCCAG ACATGTGGGG CCTGGGAAAT GAAAGAACGA 60

CTTGGGACAG GGGGATTTGG AAATGTCATC CGATGGCACA ATCAGGAGAC GGGCGAGCAG 120

ATCGCCATCA AGCAGTGCAG GCAGGAGCTC AGCCCCCGGA ACCGCGAGCG CTGGTGCCTG 180

GAGATCCAGA TCATGAGGAG GCTGAACCAC CCCAATGTGG TCGCTGCCCG GGACGTCCCC 240

GAGGGGATGC AGAACCTGGC CCCCAATGAC TTGCCCCTGC TGGCCATGGA GTACTGCCAA 300

GGAGGGGACC TCCGAAAGTA CCTGAACCAG TTCGAGAACT GCTGCGGCCT GCGGGAAGGA 360

GCCATCCTCA CCTTGCTGAG TGACATTGCC TCTGCACTTA GATACCTGCA TGAAAACAGA 420

ATCATCCACC GGGACCTAAA GCCAGAGAAC ATCGTTCTAC AGCAAGGAGA GCAAAGATTA 480

ATACACAAAA TTATTGACCT AGGATATGCC AAGGAACTGG ATCAGGGCAG TCTTTGCACT 540

TCCTTTGTGG GGACCCTGCA GTACCTGGCC CCGGAGCTGC TGGAGCAGCA GAAGTACACG 600

GTGACCGTCG ACTACTGGAG CTTTGGCACC TTGGCCTTCG AGTGCATCAC GGGCTTCCGG 660

CCCTTCCTTC CCAACTGGCA GCCTGTGCAG TGGCACTCGA AAGTCCGGCA GAAGAGTGAG 720

ATGGACATTG TCGTTAGTGA GGACTTGAAT GGAGCAGTGA AGTTTTCAAG CTCTCTACCC 780

TACCCCAATA ACCTTAACAG CGTCCTGGCG CAGCGGCTGA AGAAGTGGCT GCAGTTGATG 840

CTGATGTGGC ACCCCCGACA ACGGGGCACA GACCCCACGT ACGGGCCCAA CGGCTGCTTC 900

AAGGCCCTAG ATGACATCCT AAACCTGAAG CTGGTTCATA TCTTGAACAT GGTCACGGGC 960

ACCATTCACA CCTACCCAGT GACGGAGGAT GAGAGTCTGC AGAGCCTAAA GGCCAGAATC 1020

CAGCAGGACA CGGGGATCCC AGAGAAGGAC CAGGAGCTGC TGCAGGAGGC AGGTCTGGCC 1080

TTGATCCCGG AAAAGCCGGC CACGCAGTGC ATTTCAGACA GCAAGTTAAA TGAGGGCCGC 1140

ACGCTGGACA TGGATCTCGT TTTTCTCTTT GACAACAGTA AAGTCAACTA TGAGACTCAG 1200

ATCTCCCCAC GGCCCCAACC TGAAAGTGTC AGCTGCATCC TTCAAGAGCC CAAGAGGAAC 1260

CTCTCTTTCT TCCAGCTGCG GAAGGTGTGG GGCCAGGTCT GGCACAGCAT CCAGACGCTG 1320

AAGGAGGATT GCAACCGGCT GCAGCAGGGA CAGCGAGCTG CCATGATGAA TCTCCTCCGG 1380

AACAACAGCT GCCTGTCCAA GATGAAGAAT TCCATGGCGT CCATGTCTCA GCAGCTCAAG 1440

GCCAAGCTGG ATTTCTTCAA AACCAGCATC CAGATCGACC TGGAGAAGTA CAGTGAGCAA 1500

ACCGAGTTTG GGATCACCTC AGATAAACTG CTACTGGCCT GGAGGGAGAT GGAGCAGGCC 1560

GTGGAGCTGT GTGGGCGGGA GAACGAGGTG AAGCACCTGG TGGAACGCAT GATGGCGCTG 1620

CAGACTGACA TCGTGGACCT GCAGCGGAGC CCGATGGGCC GGAAGCCCGG GGGGACCCTG 1680

GACGACCTAG AGGAGCAGGC CAGAGAGCTG TACCGGAGAC TGCGGGAAAA ACCACGAGAC 1740

CAGCGCACGG ACGGCGACAG CCAGGAGATG GTGCGGCTGC TGCTGCAGGC CATTCAGGGC 1800

TTCGAGAAGA AAGTGCGCGT GATCTACACG CAGCTCAGCA AAACCGTGGT CTGCAAGCAG 1860

AAGGCTCTGG AGTTGCTGCC CAAGGTGGAG GAGGTGGTGG AATTAATGAA CGAGGATGAG 1920

AAGACGGTTG TTCGGCTCCA GGAGAAGCGG CAGAAGGAGC TCTGGAACCT CCTGAAGATC 1980

GCCTGCAGCA AGGTCCGAGG TCCTGTAAGT GGCAGCCCGG ACAGCATGAA TGCTTCTCGA 2040

CTGAGTCACC CTGGTCAGCT GATGTCCCAG CCCTCTGCAG CCCCCAGCAG TTTGCCTGAG 2100

TCAGCCAAGA AG 2112

Domain Profile

S: 1     WelkelLGeGafgnvikarnkktgekiavkvikeesslrprevqvrelevlrklnhkniv  60

         We+ke+LG+G+fgnvi+++n++tge+ia+k++++e+s r+re+++ e++++r+lnh+n+v

Q: 15    WEMKERLGTGGFGNVIRWHNQETGEQIAIKQCRQELSPRNRERWCLEIQIMRRLNHPNVV  74

         ************************************************************

S: 61    klvdveeel.nlasarlkvlvleyCsgGdlrkvLeepenayGLkesevlvvLsdvvaglr  119

         ++ dv+e + nla ++l++l++eyC+gGdlrk+L+++en++GL+e ++l++Lsd++++lr

Q: 75    AARDVPEGMqNLAPNDLPLLAMEYCQGGDLRKYLNQFENCCGLREGAILTLLSDIASALR  134

         ************************************************************

S: 120   yLrenkivhRDlkPenivllkgedgksiykltDlGaareldddekvvslvGteeYlaPel  179

         yL+en+i+hRDlkPenivl++g +++ i+k++DlG+a+eld++++++s+vGt++YlaPel

Q: 135   YLHENRIIHRDLKPENIVLQQG-EQRLIHKIIDLGYAKELDQGSLCTSFVGTLQYLAPEL  193

         **********************.9************************************

S: 180   yeqkkytatvDlWsiGvllyeaitGslPflpfegprrlykkitkkpakaiagtekangev  239

         +eq+kyt+tvD+Ws+G+l++e+itG++Pflp+++p+++++k+++k++ +i+++e+ ng+v

Q: 194   LEQQKYTVTVDYWSFGTLAFECITGFRPFLPNWQPVQWHSKVRQKSEMDIVVSEDLNGAV  253

         ************************************************************

S: 240   efssslPlsaslssglqeklekllanllevdeekrw  275

         +fssslP++++l+s+l+++l+k+l+++l++++++r+

Q: 254   KFSSSLPYPNNLNSVLAQRLKKWLQLMLMWHPRQRG  289

         ********************************9985

Domain Sequence
(FASTA)

WEMKERLGTG GFGNVIRWHN QETGEQIAIK QCRQELSPRN RERWCLEIQI MRRLNHPNVV 60

AARDVPEGMQ NLAPNDLPLL AMEYCQGGDL RKYLNQFENC CGLREGAILT LLSDIASALR 120

YLHENRIIHR DLKPENIVLQ QGEQRLIHKI IDLGYAKELD QGSLCTSFVG TLQYLAPELL 180

EQQKYTVTVD YWSFGTLAFE CITGFRPFLP NWQPVQWHSK VRQKSEMDIV VSEDLNGAVK 240

FSSSLPYPNN LNSVLAQRLK KWLQLMLMWH PRQRG 275

Keyword

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>