EKS-MIM-00019

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-MIM-00019

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
TKL/STKR	414.3	1.9E-124	208	489	282

Status

Unreviewed

Ensembl Protein

ENSMICP00000006253

Gene Name

ACVR1

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMICG00000006860	ENSMICP00000006253	ENSMICT00000006862

Organism

Microcebus murinus

Protein Length

503

Protein Sequence
(FASTA)

MVDGVMILPV LVMIAFPSPS MEDEKPKVNP KLYMCVCEGL SCGSEEHCEG QQCFSSLSIN 60

DGIQVYQKGC FQVYEQGKMT CKTPPSPGQA VECCQGDWCN KNITAQLPTK GKSFPGTQNF 120

HLEVGLIILS VVFAVCLLAC LLGVALRKFK RRNQERLNPR DVEYGTIEGL ITTNVGDSTL 180

ADLLDHSCTS GSGSGLPFLV QRTVARQITL LECVGKGRYG EVWRGSWQGE NVAVKIFSSR 240

DEKSWFRETE LYNTVMLRHE NILGFIASDM TSRHSSTQLW LITHYHEMGS LYDYLQLTTL 300

DTVSCLRIVL SIASGLAHLH IEIFGTQGKP AIAHRDLKSK NILVKKNGQC CIADLGLAVM 360

HSQSTNQLDV GNNPRVGTKR YMAPEVLDET IQVDCFDSYK RVDIWAFGLV LWEVARRMVS 420

NGIVRYKFYD VVPDQEDMRK VVCVDQQSPN IPNRWFSDPT LTSLAKLMKE CWYQNPSARL 480

TALRIKKTLT KIDNSLDKLK TDC 503

Nucleotide Sequence
(FASTA)

ATGGTAGATG GAGTAATGAT TCTTCCTGTG CTAGTGATGA TTGCTTTCCC TTCCCCGAGT 60

ATGGAAGATG AGAAGCCCAA GGTCAACCCC AAACTTTACA TGTGTGTGTG TGAAGGCCTC 120

TCCTGCGGTA GCGAGGAACA CTGTGAAGGC CAGCAGTGCT TCTCCTCGCT GAGCATCAAC 180

GATGGCATCC AGGTCTACCA GAAAGGCTGC TTCCAGGTCT ATGAACAGGG GAAGATGACT 240

TGTAAGACCC CACCATCCCC TGGCCAAGCC GTGGAGTGCT GCCAAGGGGA CTGGTGTAAC 300

AAGAACATCA CAGCACAGCT GCCCACTAAA GGGAAATCCT TTCCTGGAAC ACAGAACTTC 360

CACCTGGAGG TCGGCCTCAT TATTCTCTCG GTAGTGTTTG CAGTATGCCT TCTAGCCTGC 420

CTACTGGGAG TTGCTCTTCG AAAATTTAAA AGGCGCAACC AGGAACGCCT CAATCCCCGA 480

GACGTGGAGT ACGGCACCAT CGAAGGGCTC ATCACCACCA ATGTTGGAGA CAGCACTTTA 540

GCAGATTTAT TGGATCATTC GTGTACGTCA GGAAGTGGCT CTGGTCTTCC TTTTCTGGTG 600

CAAAGAACAG TGGCTCGCCA GATTACTCTC TTGGAGTGTG TTGGGAAAGG CAGGTATGGT 660

GAGGTGTGGA GAGGCAGTTG GCAAGGAGAA AATGTTGCCG TGAAGATCTT CTCCTCCCGG 720

GATGAGAAGT CATGGTTCAG GGAAACAGAA TTGTACAACA CTGTGATGCT GAGGCATGAA 780

AATATCTTAG GTTTCATTGC TTCAGATATG ACATCAAGAC ACTCCAGTAC CCAGTTGTGG 840

TTAATTACAC ACTATCATGA AATGGGATCG TTGTACGACT ATCTTCAGCT TACTACTCTG 900

GATACAGTTA GCTGCCTTCG AATAGTGCTG TCCATAGCTA GTGGTCTTGC ACATTTGCAC 960

ATAGAGATAT TTGGGACCCA AGGGAAACCA GCCATTGCCC ATCGAGATTT AAAGAGCAAA 1020

AATATCCTGG TTAAGAAGAA TGGACAGTGC TGCATAGCAG ATTTGGGCCT GGCAGTCATG 1080

CATTCCCAGA GCACCAACCA ACTTGACGTG GGCAACAACC CCCGTGTGGG CACCAAGCGC 1140

TACATGGCCC CTGAAGTTCT AGATGAAACC ATCCAGGTGG ATTGTTTTGA TTCTTACAAG 1200

AGGGTCGATA TTTGGGCCTT CGGACTTGTT TTGTGGGAAG TGGCCAGGCG GATGGTGAGC 1260

AATGGTATAG TGAGATATAA GTTCTACGAT GTGGTTCCCG ACCAGGAAGA TATGAGGAAA 1320

GTAGTCTGTG TGGATCAACA GAGCCCAAAC ATACCCAACA GATGGTTCTC AGACCCGACA 1380

TTAACCTCTC TGGCCAAGCT GATGAAAGAA TGCTGGTATC AGAATCCATC TGCAAGACTC 1440

ACAGCTCTGC GTATCAAAAA GACTTTGACC AAAATTGATA ATTCCCTAGA CAAATTGAAA 1500

ACTGACTGTT GA 1512

Domain Profile

S: 1     lklleligkGrygeVwkaklrgeevAvKifstedeaswkrEkeiyqtvllrhenilqfia  60

         ++lle++gkGrygeVw+++++ge+vAvKifs++de+sw+rE+e+y+tv+lrhenil+fia

Q: 208   ITLLECVGKGRYGEVWRGSWQGENVAVKIFSSRDEKSWFRETELYNTVMLRHENILGFIA  267

         789*********************************************************

S: 61    adkkeedsltelllvteyhekgsLsdyLkretldveellrlalslasGlahLHeeivgtk  120

         +d+++++s+t+l+l+t+yhe+gsL+dyL+ +tld+ ++lr++ls+asGlahLH ei+gt+

Q: 268   SDMTSRHSSTQLWLITHYHEMGSLYDYLQLTTLDTVSCLRIVLSIASGLAHLHIEIFGTQ  327

         ************************************************************

S: 121   gkkKpaiaHRDlkskNilvkkdltcciaDlGLalkleeekeeldlaansqvGtkRYmaPE  180

         g  KpaiaHRDlkskNilvkk+++cciaDlGLa+++++++++ld+ +n +vGtkRYmaPE

Q: 328   G--KPAIAHRDLKSKNILVKKNGQCCIADLGLAVMHSQSTNQLDVGNNPRVGTKRYMAPE  385

         *..*********************************************************

S: 181   vleealnlkdfeafkraDvYslgLvlWEvasRceevdeeveeyklpfeevvgsdPsleem  240

         vl+e++++++f+++kr+D++++gLvlWEva+R+ + +++v +    f++vv   P  e+m

Q: 386   VLDETIQVDCFDSYKRVDIWAFGLVLWEVARRMVS-NGIV-R--YKFYDVV---PDQEDM  438

         *********************************99.6665.3..4588988...788***

S: 241   kevvvekklrPkipeawkkkealkelsklleecWdadpeaRltalrvkkrl  291

         ++vv+++++ P+ip++w ++++l++l+kl++ecW+++p+aRltalr+kk+l

Q: 439   RKVVCVDQQSPNIPNRWFSDPTLTSLAKLMKECWYQNPSARLTALRIKKTL  489

         *************************************************97

Domain Sequence
(FASTA)

ITLLECVGKG RYGEVWRGSW QGENVAVKIF SSRDEKSWFR ETELYNTVML RHENILGFIA 60

SDMTSRHSST QLWLITHYHE MGSLYDYLQL TTLDTVSCLR IVLSIASGLA HLHIEIFGTQ 120

GKPAIAHRDL KSKNILVKKN GQCCIADLGL AVMHSQSTNQ LDVGNNPRVG TKRYMAPEVL 180

DETIQVDCFD SYKRVDIWAF GLVLWEVARR MVSNGIVRYK FYDVVPDQED MRKVVCVDQQ 240

SPNIPNRWFS DPTLTSLAKL MKECWYQNPS ARLTALRIKK TL 282

Keyword

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>