EKS-MIM-00018

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-MIM-00018

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/DYRK	431.1	2.2E-129	104	400	297

Status

Unreviewed

Ensembl Protein

ENSMICP00000010346

Gene Name

DYRK4

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMICG00000011365	ENSMICP00000010346	ENSMICT00000011364

Organism

Microcebus murinus

Protein Length

512

Protein Sequence
(FASTA)

MPSSELQVSE MPLHPTIKIQ HPKSEEKTPR KHKVPLTAAE ALKLFKKQLS AYEQNEILDY 60

TEIWFLGLEA QKLNVAVEKF SKTSFDDEHG SYMKVLHDHI AYRYEVLEMI GKGSFGQVAK 120

CLDHKNNELV ALKIIRNKKR FHHQALVELK ILEALRRKDK DNAYNVVHMK DFFYFRNHLC 180

ITFELLGINL YELMKNNSFQ GFSLSIVRRF TLSVLKCLQM LYVEKIIHCD LKPENIVIHQ 240

KGQVSVKVID FGSSCYEHQK VYTYIQSRFY RSPEVILGHP YDMAIDMWSL GCIMAELYMG 300

YPLFPGENEV EQLACIMEVL GLPPADFIQT ASRRQTFFDS KGFPKNITNN RGKKRYPDSK 360

DLTMVLKTYD TSFLDFVRKC LIWEPSLRMT PDQALKHAWI HEPRNLKSHP RPQTLRKSSF 420

CYLSETKKDK VRGYHHSSKK ADEIAKDATE RIKDSTTEHV QNSGGRQGSV QLPHLAEAPG 480

KAQTAGLEVS VTSTEQTRNS SPKNTNILPP IV 512

Nucleotide Sequence
(FASTA)

ATGCCATCCT CTGAGCTCCA GGTTTCAGAA ATGCCTCTGC ACCCTACCAT TAAAATCCAG 60

CACCCCAAGT CGGAGGAGAA GACACCAAGG AAGCACAAGG TGCCTCTGAC AGCGGCAGAG 120

GCCCTCAAGC TTTTTAAGAA ACAGCTGTCT GCTTATGAGC AAAATGAAAT CCTGGACTAC 180

ACAGAGATAT GGTTCCTGGG GCTTGAAGCC CAGAAGCTCA ACGTGGCTGT TGAGAAGTTC 240

AGCAAGACAA GTTTTGATGA CGAACACGGC TCCTATATGA AGGTCCTGCA CGACCACATT 300

GCCTACCGCT ACGAGGTCTT GGAGATGATC GGGAAAGGGT CCTTTGGACA GGTGGCCAAG 360

TGCTTGGATC ACAAAAACAA TGAGTTGGTG GCCCTGAAAA TCATCAGGAA CAAGAAGAGG 420

TTTCACCACC AGGCCCTGGT GGAGCTGAAG ATCCTGGAAG CTCTCAGGAG GAAGGACAAA 480

GACAATGCCT ACAACGTGGT GCACATGAAG GACTTCTTCT ACTTCCGCAA TCACCTCTGC 540

ATCACCTTCG AACTCCTGGG AATCAACTTG TATGAGTTGA TGAAGAATAA CAGCTTTCAA 600

GGCTTCAGTC TTTCCATAGT TCGGCGTTTC ACCCTCTCTG TTTTGAAGTG CTTGCAAATG 660

CTTTATGTAG AGAAAATCAT TCACTGTGAT CTCAAGCCTG AAAATATAGT GATACACCAA 720

AAGGGTCAAG TCTCTGTTAA AGTCATTGAC TTTGGATCAA GCTGTTATGA ACACCAGAAA 780

GTATACACCT ACATCCAAAG CCGGTTCTAC CGATCCCCGG AGGTGATCCT GGGCCACCCC 840

TACGACATGG CGATCGACAT GTGGAGCCTG GGCTGCATCA TGGCGGAGCT GTACATGGGC 900

TACCCTCTGT TCCCGGGGGA GAACGAGGTG GAGCAGCTGG CCTGCATCAT GGAGGTGCTG 960

GGCCTGCCGC CAGCCGACTT CATTCAGACG GCCTCCAGGA GACAGACGTT CTTCGATTCC 1020

AAAGGTTTTC CTAAAAATAT AACCAACAAC AGGGGGAAAA AAAGATACCC GGATTCCAAG 1080

GATCTCACGA TGGTGCTGAA AACCTATGAT ACCAGCTTCC TGGACTTTGT CAGAAAGTGT 1140

TTGATATGGG AACCTTCTCT TCGAATGACC CCTGACCAGG CCCTCAAGCA TGCTTGGATT 1200

CATGAGCCAC GGAACCTCAA ATCACATCCC AGGCCCCAGA CCCTGAGGAA ATCCAGTTTT 1260

TGTTACCTCT CTGAGACAAA GAAGGACAAG GTTCGAGGGT ATCATCACTC GAGCAAAAAA 1320

GCAGATGAGA TTGCCAAAGA TGCTACAGAA AGAATAAAAG ACAGCACCAC CGAGCACGTC 1380

CAGAATTCAG GTGGCCGGCA GGGCTCTGTC CAGCTGCCTC ACCTAGCAGA GGCACCCGGG 1440

AAGGCACAGA CGGCTGGGCT AGAGGTGTCC GTGACCTCCA CAGAACAGAC CAGAAACTCC 1500

TCCCCCAAGA ACACAAACAT TCTGCCACCT ATTGTATGA 1539

Domain Profile

S: 1     yevlevigkGsfgqVvkaldkktkeivaikiiknkkrfarqaqeEveiLeklnkkdkeek  60

         yevle+igkGsfgqV+k+ld+k++e va+kii+nkkrf++qa  E++iLe+l++kdk+++

Q: 104   YEVLEMIGKGSFGQVAKCLDHKNNELVALKIIRNKKRFHHQALVELKILEALRRKDKDNA  163

         9***********************************************************

S: 61    ynvvrllelfvfrnhlclvfellsqnLyellkknkfsglslklvrklaqqilkaLklLke  120

         ynvv+++++f+frnhlc++fell +nLyel+k+n+f+g+sl++vr+++ ++lk+L++L+

Q: 164   YNVVHMKDFFYFRNHLCITFELLGINLYELMKNNSFQGFSLSIVRRFTLSVLKCLQMLYV  223

         ************************************************************

S: 121   lkiiHaDlKPeNillvekkrsevkviDFGsssavsqkeiytyiqsrfYraPEiilglkyd  180

         +kiiH+DlKPeNi++ +k++ +vkviDFGss++++qk +ytyiqsrfYr+PE+ilg++yd

Q: 224   EKIIHCDLKPENIVIHQKGQVSVKVIDFGSSCYEHQK-VYTYIQSRFYRSPEVILGHPYD  282

         *************************************.**********************

S: 181   eaiDmWSlGcvlaElftGkpLfpGenevdqlalivevlglppekllekakkakkfftkke  240

         +aiDmWSlGc++aEl++G+pLfpGenev+qla+i+evlglpp+ ++++a+++++ff++k+

Q: 283   MAIDMWSLGCIMAELYMGYPLFPGENEVEQLACIMEVLGLPPADFIQTASRRQTFFDSKG  342

         ************************************************************

S: 241   apkyilktkksdrkkklvlnvkkaakkrkaplskelgealkekedklfkdllkrmleldp  300

         +pk i+                ++  k+++p sk+l+++lk+++++ f d+++++l ++p

Q: 343   FPKNIT----------------NNRGKKRYPDSKDLTMVLKTYDTS-FLDFVRKCLIWEP  385

         *99766................34456789999***9999998877.*************

S: 301   akRitpkealkhpfv  315

         + R+tp++alkh ++

Q: 386   SLRMTPDQALKHAWI  400

         *************97

Domain Sequence
(FASTA)

YEVLEMIGKG SFGQVAKCLD HKNNELVALK IIRNKKRFHH QALVELKILE ALRRKDKDNA 60

YNVVHMKDFF YFRNHLCITF ELLGINLYEL MKNNSFQGFS LSIVRRFTLS VLKCLQMLYV 120

EKIIHCDLKP ENIVIHQKGQ VSVKVIDFGS SCYEHQKVYT YIQSRFYRSP EVILGHPYDM 180

AIDMWSLGCI MAELYMGYPL FPGENEVEQL ACIMEVLGLP PADFIQTASR RQTFFDSKGF 240

PKNITNNRGK KRYPDSKDLT MVLKTYDTSF LDFVRKCLIW EPSLRMTPDQ ALKHAWI 297

Keyword

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dasypus novemcinctus"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>