EKS-MIM-00021

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-MIM-00021

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
TKL/STKR	408.7	1.0E-122	172	459	288

Status

Unreviewed

Ensembl Protein

ENSMICP00000011708

Gene Name

ACVR2B

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMICG00000012850	ENSMICP00000011708	ENSMICT00000012851

Organism

Microcebus murinus

Protein Length

493

Protein Sequence
(FASTA)

SGRGEAETRE CIYYNANWEL ERTNQSGLER CEGEQDKRLH CYASWRNSSG TIELVKKGCW 60

LDDFNCYDRQ ECVATEENPQ VYFCCCEGNF CNERFTHLPE AGSPEVTYEP PPTAPTLLTV 120

LAYSLLPIGG LSLIVLLAFW MYRHRKPPYG HVDIHEDPGP PPPSPLVGLK PLQLLEIKAR 180

GRFGCVWKAQ LMNDFVAVKI FPLQDKQSWQ SEREIFSTPG MKHENLLQFI AAEKRGSNLE 240

VELWLITAFH DKGSLTDYLK GNIITWNELC HVAETMSRGL SYLHEDVPWC RGEGHKPSIA 300

HRDFKSKNVL LKSDLTAVLA DFGLAVRFEP GKPPGDTHGQ VGTRRYMAPE VLEGAINFQR 360

DAFLRIDMYA MGLVLWELVS RCKAADGPVD EYMLPFEEEI GQHPSLEELQ EVVVHKKMRP 420

TIKDHWLKHP GLAQLCVTIE ECWDHDAEAR LSAGCVEERV SLIRSVNGTT SDCLVSLVTS 480

VTNVDLPPKE SSI 493

Nucleotide Sequence
(FASTA)

TCCGGGCGCG GAGAGGCTGA GACCCGGGAG TGCATCTACT ACAATGCCAA CTGGGAGCTG 60

GAGCGTACCA ACCAGAGCGG CCTGGAGCGC TGTGAGGGTG AGCAGGACAA GCGACTGCAC 120

TGCTACGCCT CCTGGCGCAA CAGCTCTGGC ACCATCGAGC TTGTCAAGAA GGGCTGCTGG 180

CTGGACGACT TCAACTGCTA CGACAGGCAG GAGTGTGTGG CCACCGAGGA GAACCCCCAG 240

GTGTACTTCT GCTGCTGTGA AGGCAACTTC TGCAACGAGC GCTTTACCCA CCTGCCAGAG 300

GCTGGGAGCC CGGAAGTCAC GTACGAGCCA CCCCCGACAG CCCCCACCCT GCTCACGGTG 360

CTGGCCTACT CGCTGCTGCC CATTGGGGGC CTCTCTCTCA TTGTCCTGCT GGCCTTCTGG 420

ATGTACCGGC ATCGTAAACC CCCATATGGC CATGTGGACA TCCATGAGGA CCCCGGGCCT 480

CCACCCCCAT CCCCTCTAGT GGGCCTGAAG CCACTGCAGC TGCTGGAGAT CAAGGCTCGG 540

GGGCGCTTTG GCTGTGTCTG GAAAGCCCAG CTCATGAACG ACTTTGTGGC TGTCAAGATC 600

TTCCCACTCC AGGACAAGCA GTCATGGCAG AGTGAACGGG AGATCTTCAG CACGCCTGGC 660

ATGAAGCATG AGAACCTGCT ACAGTTCATC GCCGCTGAGA AGCGAGGCTC CAACCTTGAA 720

GTGGAGCTGT GGCTCATCAC GGCCTTCCAT GACAAGGGCT CCCTCACGGA TTACCTCAAG 780

GGGAACATCA TCACTTGGAA CGAACTGTGT CACGTGGCAG AGACGATGTC ACGAGGCCTC 840

TCATACCTGC ATGAGGATGT GCCCTGGTGC CGTGGCGAGG GCCACAAGCC GTCTATTGCC 900

CACAGGGACT TCAAAAGCAA GAATGTATTG CTGAAGAGCG ACCTCACGGC TGTGCTGGCT 960

GACTTTGGCC TGGCCGTTCG GTTTGAGCCA GGGAAACCTC CAGGGGACAC CCATGGGCAG 1020

GTGGGCACGA GAAGGTACAT GGCCCCTGAG GTGCTCGAGG GAGCCATCAA CTTCCAGAGA 1080

GATGCCTTCC TGCGCATCGA TATGTATGCC ATGGGGCTGG TGCTGTGGGA GCTCGTGTCT 1140

CGCTGCAAGG CCGCAGATGG ACCTGTGGAT GAGTACATGC TGCCTTTTGA GGAAGAGATC 1200

GGCCAGCACC CGTCGCTGGA GGAGCTGCAG GAGGTGGTTG TGCACAAGAA GATGAGGCCC 1260

ACCATTAAGG ATCACTGGCT GAAGCACCCG GGCCTGGCCC AGCTCTGTGT GACCATCGAG 1320

GAGTGCTGGG ACCATGATGC TGAGGCCCGC CTGTCGGCGG GCTGTGTGGA GGAGCGGGTG 1380

TCCCTGATCC GGTCGGTCAA CGGCACTACC TCGGACTGTC TTGTCTCCCT GGTGACCTCT 1440

GTCACCAATG TGGACCTGCC GCCTAAAGAG TCAAGCATCT AA 1482

Domain Profile

S: 1     lklleligkGrygeVwkaklrgeevAvKifstedeaswkrEkeiyqtvllrhenilqfia  60

         l+lle+ ++Gr+g+Vwka+l+++ vAvKif+ +d++sw++E+ei++t+ ++hen+lqfia

Q: 172   LQLLEIKARGRFGCVWKAQLMNDFVAVKIFPLQDKQSWQSEREIFSTPGMKHENLLQFIA  231

         6899********************************************************

S: 61    adkkeedsltelllvteyhekgsLsdyLkretldveellrlalslasGlahLHeeivgtk  120

         a+k+ +++++el+l+t++h+kgsL+dyLk ++++++el+++a+++++Gl++LHe++++++

Q: 232   AEKRGSNLEVELWLITAFHDKGSLTDYLKGNIITWNELCHVAETMSRGLSYLHEDVPWCR  291

         ************************************************************

S: 121   g.kkKpaiaHRDlkskNilvkkdltcciaDlGLalkleeekeeldlaansqvGtkRYmaP  179

         g  +Kp+iaHRD+kskN+l+k+dlt+++aD+GLa+++e  k   d  ++ qvGt+RYmaP

Q: 292   GeGHKPSIAHRDFKSKNVLLKSDLTAVLADFGLAVRFEPGKPPGD--THGQVGTRRYMAP  349

         *99***************************************888..79***********

S: 180   EvleealnlkdfeafkraDvYslgLvlWEvasRceevdeeveeyklpfeevvgsdPslee  239

         Evle+a+n+++ +af r+D+Y++gLvlWE++sRc+++d+ v+ey+lpfee++g++Pslee

Q: 350   EVLEGAINFQR-DAFLRIDMYAMGLVLWELVSRCKAADGPVDEYMLPFEEEIGQHPSLEE  408

         **********9.9***********************************************

S: 240   mkevvvekklrPkipeawkkkealkelsklleecWdadpeaRltalrvkkr  290

         ++evvv+kk+rP+i+++w k++ l++l+ ++eecWd+d+eaRl+a +v++r

Q: 409   LQEVVVHKKMRPTIKDHWLKHPGLAQLCVTIEECWDHDAEARLSAGCVEER  459

         ************************************************998

Domain Sequence
(FASTA)

LQLLEIKARG RFGCVWKAQL MNDFVAVKIF PLQDKQSWQS EREIFSTPGM KHENLLQFIA 60

AEKRGSNLEV ELWLITAFHD KGSLTDYLKG NIITWNELCH VAETMSRGLS YLHEDVPWCR 120

GEGHKPSIAH RDFKSKNVLL KSDLTAVLAD FGLAVRFEPG KPPGDTHGQV GTRRYMAPEV 180

LEGAINFQRD AFLRIDMYAM GLVLWELVSR CKAADGPVDE YMLPFEEEIG QHPSLEELQE 240

VVVHKKMRPT IKDHWLKHPG LAQLCVTIEE CWDHDAEARL SAGCVEER 288

Keyword

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>