EKS-MIM-00035

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-MIM-00035

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
STE/STE20	322.2	2.0E-96	292	539	248

Status

Unreviewed

Ensembl Protein

ENSMICP00000012721

Gene Name

PAK4

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMICG00000013952	ENSMICP00000012721	ENSMICT00000013950

Organism

Microcebus murinus

Protein Length

558

Protein Sequence
(FASTA)

KFTGLPRQWQ SLIEESARRP KPLVDPACIT SIQPGAPKTI VRGSKGAKDG ALTLLLDEFE 60

NMSVTRSNSL RRDSPPPPTR ARQENGMPEE QAATARGGPG KAGGRGRVAG HSEAGGSSGD 120

RRRVGPEKRP KSSREGSGGP QESSRDKRPL SGPDVGTPQP ANLAGGAKLA AGRPFNTYPR 180

ADTDHPSRGA QGEPREMAPN GPSAGGLPVP QSSSRPPTRT RGPPGPGVLG PHASEPQLAP 240

PARTPAAPAA PGPPGPRSPQ REPQRVSHEQ FRAALQLVVD PGDPRSYLDN FIKIGEGSTG 300

IVCIATIRSS GKLVAVKKMD LRKQQRRELL FNEVVIMRDY QHENVVEMYN SYLVGDELWV 360

VMEFLEGGAL TDIVTHTRMN EEQIAAVCLA VLQALSVLHA QGVIHRDIKS DSILLTHDGR 420

VKLSDFGFCA QVSKEVPRRK SLVGTPYWMA PELISRLPYG PEVDIWSLGV MVIEMVDGEP 480

PYFNEPPLKA MKMIRDNLPP RLKNLHKVSP SLKGFLDRLL VRDPAQRATA AELLKHPFLA 540

KAGPPASIVP LMRQNRTR 558

Nucleotide Sequence
(FASTA)

AAGTTCACGG GGCTGCCCCG CCAGTGGCAG AGCCTGATCG AGGAGTCGGC TCGGCGGCCC 60

AAGCCGCTGG TGGACCCCGC CTGCATCACC TCCATCCAGC CCGGGGCCCC AAAGACCATC 120

GTGCGGGGCA GCAAAGGTGC CAAGGATGGG GCCCTCACGC TGCTGCTGGA CGAGTTTGAG 180

AACATGTCGG TGACACGCTC CAACTCCTTG CGGAGAGACA GCCCGCCGCC ACCCACCCGT 240

GCCCGCCAGG AAAACGGGAT GCCGGAGGAA CAGGCCGCCA CGGCCAGAGG GGGCCCGGGG 300

AAGGCGGGCG GCCGAGGCCG GGTCGCTGGT CACAGCGAGG CGGGTGGCAG CAGTGGTGAC 360

AGGCGGCGGG TCGGGCCGGA GAAGAGGCCC AAGTCTTCCA GGGAGGGCTC AGGGGGCCCC 420

CAGGAGTCCT CCCGGGACAA ACGCCCCCTC TCCGGGCCTG ACGTTGGCAC CCCCCAGCCT 480

GCCAATCTGG CCGGCGGGGC GAAACTGGCG GCCGGCCGGC CCTTTAACAC GTACCCGAGG 540

GCCGATACGG ACCACCCGTC CCGGGGTGCC CAGGGTGAGC CTCGAGAAAT GGCCCCCAAT 600

GGGCCATCAG CGGGGGGCCT GCCCGTCCCC CAGTCCTCCT CCCGGCCTCC CACCCGCACC 660

CGCGGCCCCC CCGGCCCTGG AGTGCTGGGC CCCCATGCCT CCGAGCCCCA GCTGGCCCCT 720

CCAGCCCGCA CCCCGGCCGC CCCCGCTGCC CCTGGGCCGC CCGGTCCCCG CTCGCCACAG 780

CGCGAACCGC AGCGAGTGTC GCACGAGCAG TTCCGGGCTG CTCTGCAGCT GGTGGTGGAC 840

CCAGGTGACC CTCGCTCCTA CCTGGACAAC TTCATCAAGA TCGGCGAGGG CTCCACTGGC 900

ATCGTGTGCA TTGCCACCAT CCGCAGCTCG GGCAAGCTGG TGGCCGTCAA GAAGATGGAC 960

CTGCGCAAGC AGCAGAGGCG AGAGCTGCTC TTCAACGAGG TGGTGATCAT GCGGGACTAC 1020

CAGCACGAGA ACGTGGTGGA GATGTACAAC AGCTACCTGG TGGGGGACGA GCTCTGGGTG 1080

GTGATGGAGT TCCTGGAAGG AGGTGCCCTC ACTGACATCG TCACCCACAC CAGGATGAAC 1140

GAGGAGCAGA TCGCCGCCGT GTGCCTGGCC GTGCTGCAGG CCCTGTCTGT GCTCCACGCC 1200

CAGGGCGTCA TCCACCGGGA CATCAAGAGC GACTCCATCC TGCTGACCCA CGATGGCAGG 1260

GTGAAGCTGT CAGACTTCGG CTTCTGTGCC CAGGTGAGCA AGGAGGTGCC ACGGAGGAAG 1320

TCGCTGGTCG GCACGCCATA CTGGATGGCC CCGGAGCTCA TCTCCCGGCT TCCCTACGGG 1380

CCTGAGGTGG ACATCTGGTC GCTGGGCGTC ATGGTGATCG AGATGGTGGA TGGGGAGCCT 1440

CCCTACTTCA ACGAGCCGCC CCTCAAAGCC ATGAAGATGA TTCGGGACAA CCTGCCACCC 1500

CGACTGAAGA ACCTGCACAA GGTGTCACCC TCCCTGAAGG GCTTCCTGGA CCGCCTGCTG 1560

GTCCGCGACC CGGCGCAGCG GGCCACGGCG GCCGAGCTGC TGAAGCACCC GTTCCTGGCC 1620

AAGGCGGGGC CGCCCGCCAG CATCGTGCCG CTCATGCGCC AGAACCGCAC CAGATGA 1677

Domain Profile

S: 5     eeigkGalgkvylarekktgelvaikkinlekqekleelqkeisvlkklkhpniveyles  64

          +ig+G++g v++a+ +++g+lva+kk++l+kq++ e+l++e+ ++++++h+n+ve+++s

Q: 292   IKIGEGSTGIVCIATIRSSGKLVAVKKMDLRKQQRRELLFNEVVIMRDYQHENVVEMYNS  351

         68**********************************************************

S: 65    flkeeelwlvmeylagGslsdlvkeelkselkEeqiayilrevlkaLeylHskkviHrdi  124

         +l+ +elw+vme+l+gG+l+d+v+   +++++Eeqia+++  vl+aL+ lH+++viHrdi

Q: 352   YLVGDELWVVMEFLEGGALTDIVT---HTRMNEEQIAAVCLAVLQALSVLHAQGVIHRDI  408

         ************************...9********************************

S: 125   kakniLlteegeVkLsdfgvaaqlektrkkrktvvgtpywmAPEviaqeekgYdekaDiw  184

         k+++iLlt++g+VkLsdfg++aq++k++ +rk++vgtpywmAPE+i+  +  Y  ++Diw

Q: 409   KSDSILLTHDGRVKLSDFGFCAQVSKEVPRRKSLVGTPYWMAPELIS--RLPYGPEVDIW  466

         ***********************************************..9**********

S: 185   slGItaielaegepPfkdleplkallkilkneppklkskkkfskefkefvekclqknpek  244

         slG+++ie+++gepP+++++plka+ +i +n pp+lk+ +k+s+++k f++++l ++p++

Q: 467   SLGVMVIEMVDGEPPYFNEPPLKAMKMIRDNLPPRLKNLHKVSPSLKGFLDRLLVRDPAQ  526

         ************************************************************

S: 245   RpsasellkhkFl  257

         R++a+ellkh+Fl

Q: 527   RATAAELLKHPFL  539

         ************7

Domain Sequence
(FASTA)

IKIGEGSTGI VCIATIRSSG KLVAVKKMDL RKQQRRELLF NEVVIMRDYQ HENVVEMYNS 60

YLVGDELWVV MEFLEGGALT DIVTHTRMNE EQIAAVCLAV LQALSVLHAQ GVIHRDIKSD 120

SILLTHDGRV KLSDFGFCAQ VSKEVPRRKS LVGTPYWMAP ELISRLPYGP EVDIWSLGVM 180

VIEMVDGEPP YFNEPPLKAM KMIRDNLPPR LKNLHKVSPS LKGFLDRLLV RDPAQRATAA 240

ELLKHPFL 248

Keyword

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>