EKS-MIM-00057

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-MIM-00057

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
STE/STE11	349.7	9.7E-105	650	906	257

Status

Unreviewed

Ensembl Protein

ENSMICP00000014370

Gene Name

MAP3K6

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMICG00000015758	ENSMICP00000014370	ENSMICT00000015771

Organism

Microcebus murinus

Protein Length

1289

Protein Sequence
(FASTA)

MAGSCARSGA QRAGSCWQDP LAEALSRGRP LAGSSGRGCA RSRPLSVVYV LTREPRPGVE 60

PGEGTETEPL PLRCLREACA QLSGPRPPPQ LRSLPFGTLA LGDTAALDSF YNADVVVLEV 120

SSSLAQPSLF YHLGVRESFS MTNNVLLCSQ ADLPDLQALR EDVFQRNSDC VGSYTLIPYV 180

VTATGRVLCG DVGLLRGLAD GLVQAGVGTE ALLTPLVGRL ARLLEATPTD SCGYFRETIR 240

QDIRRARERF SGQQLRQELA RLQRRLDSVE LLSPDIIMNL LLSYRDVQDY SAIIELVETL 300

QALPTCDVAE QHNVCFHYTF ALNRRNKPGD REKPLAVMLP LVQFEVSVPP DLYCMCARVY 360

KDMFFSSGFQ DGRHREQAYH WYRKAFDVEP SLHSGINAAV LLVAAGQHFE DSEELRLIGM 420

KLGCLLARKG CVEKMQYYWD VGFYLGAQIL ANDPTQVVLA AEQLYKLNAP IWYLVSVMET 480

FLLYRHFRPM PQPSGGPPRH AHFWLHFLLQ SCQPFNTTSP QGDQCLVLVL EMNKVLLPAQ 540

VEVRGRDPVS AVILSLLHGE TQDFPARWTF PVASICGVSA SKRDERCCFL YALPPAQDVQ 600

LCFPSVGHCQ WFCSLIQALV TNPDSSAPTE AAGGVGEVLE FDYEYTETGE RLVLGKGTYG 660

VVYAGRERHT RVRIAIKEIP ERDSRFSQPL HEEIALHKRL RHKNIVRYLG SASQGGYLKI 720

FMEEVPGGSL SSLLRSVWGP LKDNESTISF YTRQILQGLS YLHDNHIVHR DIKGDNVLIN 780

TFSGLLKISD FGTSKRLAGI TPCTETFTGT LQYMAPEIID QGPRGYGKAA DIWSLGCTVI 840

EMATGRPPFH ELGSPQAAMF QVGMYKVHPP MPSSLSAEAQ AFLLRTFEPD PRLRASAQAL 900

LRDSFLQPGK RSRSPGSPQH APRPSDVPST SSTPSADATT QSQTFPRPQA PSQHPPSPPK 960

RCLSYGDTSQ LRVPEEPGAE EPASPEESSG LSLLHQESKR RAMLAEVLEQ ELATLAESLL 1020

LEQEQEQEQG SHLGRDHVEQ LLRCLGAHIH TPNRRQLVQE LRALQGQLRA KGLGPTLLHG 1080

PLFAFPDAVK QILRRRQIRP HWMFVLDSLL SRAVRAALAV LSPEVEEEAV PSKSELSKEG 1140

ESQQNPGQQS PLPAEPAQGP PPLVQLSLLR AETDRLRQVL AEKERECQAL VQRALQRVNA 1200

EARADALASE PPAALPADQG LVQWLQELSV DSATIQTLLN HSFTLHALLT CATRDDLIYT 1260

RIRGGMVCRI WRAILAQRAG PMPVTPGPR 1289

Nucleotide Sequence
(FASTA)

ATGGCGGGGT CGTGCGCCCG GTCCGGGGCG CAGCGCGCCG GCAGCTGCTG GCAGGACCCG 60

CTGGCCGAGG CACTGAGCAG GGGTCGGCCG CTAGCTGGGT CCTCGGGCCG GGGCTGCGCG 120

CGGAGCCGGC CGCTCAGCGT GGTCTACGTG CTGACCCGGG AGCCGCGGCC CGGGGTGGAG 180

CCTGGGGAGG GCACCGAGAC CGAGCCGCTG CCCCTGCGCT GCCTGCGCGA GGCTTGCGCG 240

CAGCTCTCCG GGCCGCGGCC GCCGCCGCAG CTGCGCAGCC TGCCCTTTGG GACACTGGCG 300

CTGGGCGACA CCGCGGCGCT GGACTCCTTC TACAACGCGG ACGTGGTGGT TCTGGAGGTG 360

AGCAGCTCTC TGGCACAGCC CTCCCTGTTC TACCACCTCG GTGTGCGTGA GAGCTTCAGC 420

ATGACCAACA ACGTGCTCCT CTGCTCCCAG GCAGACCTCC CCGACCTGCA GGCCCTGCGG 480

GAGGATGTTT TCCAGAGGAA CTCGGATTGC GTTGGCAGCT ACACACTGAT CCCCTATGTG 540

GTGACAGCCA CTGGTCGGGT GCTGTGTGGT GACGTAGGGC TTCTCAGAGG CCTGGCTGAT 600

GGCCTCGTAC AGGCTGGAGT GGGCACTGAG GCCCTGCTCA CCCCTCTGGT GGGCCGGCTT 660

GCCCGCCTGC TGGAGGCCAC ACCCACGGAC TCTTGTGGCT ATTTCCGGGA GACCATTCGG 720

CAGGATATCA GGCGGGCACG GGAGCGGTTC AGCGGGCAGC AGCTGCGGCA GGAGCTGGCC 780

CGCCTGCAGC GGAGACTGGA CAGCGTGGAG CTGCTGAGCC CCGACATCAT CATGAACTTG 840

CTGCTGTCCT ACCGCGACGT GCAGGACTAC TCGGCCATCA TTGAGCTGGT GGAGACGCTG 900

CAGGCCTTGC CCACCTGCGA TGTGGCCGAG CAGCACAATG TCTGCTTCCA CTACACGTTC 960

GCCCTCAACC GGAGGAACAA GCCTGGGGAC CGGGAGAAGC CACTGGCTGT CATGCTACCA 1020

CTGGTACAGT TTGAGGTCTC TGTGCCACCT GATCTATACT GCATGTGTGC CCGTGTGTAC 1080

AAGGACATGT TCTTCAGCTC TGGCTTCCAG GATGGTAGGC ACCGAGAGCA GGCCTATCAC 1140

TGGTACCGCA AGGCTTTTGA TGTGGAGCCC AGCCTCCACT CGGGCATCAA TGCCGCTGTG 1200

CTCCTCGTTG CTGCTGGCCA GCACTTTGAG GACTCCGAGG AGCTCCGGCT AATAGGCATG 1260

AAGCTGGGCT GTCTGCTGGC CCGAAAAGGC TGTGTGGAGA AGATGCAGTA TTACTGGGAT 1320

GTAGGTTTCT ACCTGGGAGC CCAGATCCTC GCCAATGACC CCACCCAGGT GGTGCTGGCT 1380

GCAGAACAGC TGTACAAGCT CAATGCCCCC ATATGGTACC TGGTGTCTGT GATGGAAACC 1440

TTCCTGCTCT ACCGACACTT CAGACCCATG CCACAGCCGT CTGGAGGACC TCCACGCCAT 1500

GCCCACTTCT GGCTACACTT CTTGCTACAG TCCTGCCAGC CATTCAACAC AACCTCTCCC 1560

CAGGGGGATC AGTGCTTGGT GCTGGTCCTG GAGATGAACA AGGTGCTGCT GCCAGCGCAG 1620

GTGGAGGTTC GGGGTAGGGA CCCGGTGAGC GCAGTGATCC TGAGCCTGCT GCATGGGGAG 1680

ACCCAGGACT TTCCCGCCAG GTGGACCTTC CCAGTTGCCT CCATCTGCGG AGTCAGTGCC 1740

TCCAAGCGGG ACGAGCGCTG CTGCTTCCTT TATGCGCTGC CCCCCGCCCA GGACGTCCAG 1800

CTGTGCTTCC CCAGCGTAGG GCACTGCCAG TGGTTCTGCA GCCTGATCCA GGCCTTGGTG 1860

ACGAATCCGG ATTCCTCGGC GCCCACGGAA GCGGCAGGGG GCGTGGGAGA GGTGCTGGAG 1920

TTTGATTATG AGTACACGGA GACCGGCGAG CGGCTGGTGC TGGGCAAGGG CACGTACGGG 1980

GTGGTATACG CGGGCCGCGA GCGGCACACG AGGGTACGCA TCGCCATCAA GGAGATCCCG 2040

GAGCGGGACA GCAGGTTCTC TCAGCCCCTG CATGAGGAGA TCGCTCTTCA CAAACGCCTG 2100

CGCCACAAGA ACATCGTGCG CTACCTGGGC TCAGCTAGCC AGGGCGGCTA CCTTAAGATC 2160

TTCATGGAGG AAGTGCCTGG AGGTAGCCTG TCTTCCTTGC TGCGGTCAGT GTGGGGACCC 2220

CTGAAGGACA ACGAGAGCAC CATCAGCTTC TACACCCGCC AGATCCTGCA GGGACTCAGC 2280

TACCTGCACG ACAACCATAT TGTGCACCGG GACATCAAGG GGGACAATGT GCTGATCAAT 2340

ACCTTCAGTG GGCTGCTCAA GATTTCTGAC TTCGGCACCT CCAAGCGGCT GGCGGGCATC 2400

ACACCCTGCA CTGAGACCTT CACAGGGACC CTGCAGTATA TGGCTCCAGA AATCATTGAC 2460

CAGGGCCCAC GAGGGTATGG GAAGGCGGCT GACATCTGGT CATTGGGCTG CACTGTAATC 2520

GAGATGGCCA CAGGTCGCCC ACCCTTCCAC GAGCTGGGGA GCCCACAGGC TGCCATGTTT 2580

CAGGTGGGCA TGTACAAGGT GCATCCACCA ATGCCCAGTT CTCTGTCTGC TGAAGCCCAA 2640

GCCTTCCTCC TTCGAACTTT TGAACCAGAC CCCCGCCTCC GAGCCAGCGC CCAAGCACTG 2700

CTGAGGGACT CCTTCCTACA GCCTGGGAAG AGGAGCCGCA GCCCTGGCTC TCCCCAACAT 2760

GCTCCACGGC CCTCAGATGT CCCTTCCACC AGTTCTACTC CTTCAGCTGA CGCGACCACA 2820

CAGTCCCAGA CTTTCCCACG CCCTCAGGCA CCCTCTCAAC ACCCGCCCAG CCCACCGAAG 2880

CGCTGCCTCA GTTATGGGGA CACCAGCCAG CTCCGGGTGC CTGAGGAGCC TGGGGCCGAG 2940

GAGCCTGCAT CCCCGGAGGA GAGTTCGGGG CTGAGCCTGT TGCACCAGGA GAGCAAGCGC 3000

CGGGCCATGC TGGCCGAGGT GCTGGAGCAG GAGCTGGCCA CGCTGGCGGA GAGTCTGCTC 3060

CTGGAGCAGG AGCAGGAGCA GGAGCAGGGT TCCCATCTGG GCAGGGATCA TGTGGAACAG 3120

CTGCTGCGCT GCCTCGGGGC GCACATCCAC ACTCCCAACC GCCGGCAGCT GGTCCAGGAG 3180

CTCCGGGCGC TGCAAGGGCA GCTTCGAGCC AAGGGCCTTG GGCCTACACT TCTGCACGGA 3240

CCGCTCTTTG CCTTCCCGGA TGCGGTGAAG CAGATCCTCC GCAGGCGCCA GATCCGCCCA 3300

CACTGGATGT TCGTGCTGGA CTCGCTGCTC AGCCGCGCGG TGCGGGCCGC CCTGGCTGTG 3360

CTGAGCCCGG AGGTGGAGGA GGAGGCAGTC CCATCGAAGT CAGAGTTGAG TAAAGAGGGG 3420

GAGTCTCAGC AGAACCCGGG CCAGCAGAGC CCGCTCCCCG CGGAACCCGC GCAGGGCCCC 3480

CCACCTCTCG TGCAGCTGAG TCTCCTGCGA GCGGAGACTG ATAGGCTTCG CCAAGTCCTG 3540

GCTGAGAAGG AACGTGAGTG CCAGGCCCTA GTGCAGCGGG CGCTGCAGCG GGTGAATGCG 3600

GAGGCCAGGG CCGACGCCCT GGCCTCAGAG CCCCCAGCTG CTCTCCCAGC GGACCAGGGC 3660

CTGGTGCAGT GGCTACAGGA ACTGAGTGTG GATTCAGCCA CCATCCAAAC GCTGCTGAAC 3720

CACAGCTTCA CCCTCCATGC CCTGCTCACC TGTGCCACTC GAGATGACCT CATCTACACC 3780

CGCATCAGGG GAGGGATGGT ATGCCGCATC TGGAGAGCCA TCTTGGCACA GCGAGCAGGA 3840

CCCATGCCAG TTACCCCTGG ACCCCGG 3867

Domain Profile

S: 3     krevigkGsfgsvyaaldvdtgellavKeveikpekksekkevkalkeEikllkelkHen  62

         +r v+gkG++g vya+++ +t+ ++a+Ke+   pe++s+   +++l+eEi+l+k+l+H+n

Q: 650   ERLVLGKGTYGVVYAGRERHTRVRIAIKEI---PERDSR--FSQPLHEEIALHKRLRHKN  704

         5779**************************...888775..9******************

S: 63    ivkyyGveveeeelkiflEyvegGslsslle.kygkle..esvikkytkqileglayLHe  119

         iv+y+G++++ ++lkif+E v+gGslssll+  +g+l+  es+i++yt+qil+gl+yLH+

Q: 705   IVRYLGSASQGGYLKIFMEEVPGGSLSSLLRsVWGPLKdnESTISFYTRQILQGLSYLHD  764

         *******************************99****9999*******************

S: 120   kkivHRDiKgaNillds.sgvvklsDFGaskrlaelntkaaelesltGtlaymaPEvikk  178

         ++ivHRDiKg+N+l+++ sg++k+sDFG+skrla ++++   +e++tGtl+ymaPE+i++

Q: 765   NHIVHRDIKGDNVLINTfSGLLKISDFGTSKRLAGITPC---TETFTGTLQYMAPEIIDQ  821

         *****************9*********************...8*****************

S: 179   kekgygrkaDiWslgcvviemltgkrPfaeldeelaimfkvgakktkPeipeklseegkd  238

         + +gyg++aDiWslgc+viem+tg++Pf+el++++a+mf+vg+ k++P++p++ls+e+++

Q: 822   GPRGYGKAADIWSLGCTVIEMATGRPPFHELGSPQAAMFQVGMYKVHPPMPSSLSAEAQA  881

         ************************************************************

S: 239   flekcleldpkkrpsaeeLLkhefl  263

         fl +++e dp+ r+sa+ LL+++fl

Q: 882   FLLRTFEPDPRLRASAQALLRDSFL  906

         **********************996

Domain Sequence
(FASTA)

ERLVLGKGTY GVVYAGRERH TRVRIAIKEI PERDSRFSQP LHEEIALHKR LRHKNIVRYL 60

GSASQGGYLK IFMEEVPGGS LSSLLRSVWG PLKDNESTIS FYTRQILQGL SYLHDNHIVH 120

RDIKGDNVLI NTFSGLLKIS DFGTSKRLAG ITPCTETFTG TLQYMAPEII DQGPRGYGKA 180

ADIWSLGCTV IEMATGRPPF HELGSPQAAM FQVGMYKVHP PMPSSLSAEA QAFLLRTFEP 240

DPRLRASAQA LLRDSFL 257

Keyword

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>