EPS-MYL-00024

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-MYL-00024

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPM/PP2C	255.5	6.6E-76	56	367	312

Status

Unreviewed

Ensembl Protein

ENSMLUP00000000432

UniProt Accession

G1NTE0;

Protein Name

Protein Synonyms/Alias

Gene Name

PPM1D

Gene Synonyms/Alias

PPM1D;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMLUG00000000476	ENSMLUP00000000432	ENSMLUT00000000475

Organism

Myotis lucifugus

Functional Description

Protein Length

599

Protein Sequence
(FASTA)

MAGLYSLGVS VFSDQGGRKY MEDVTQIVVE PEPTAEEKRS PRRSLSQPSP PALPGGEVSG 60

KGPAVGAREA GDPAPDAGAS PAPGRCCRRR SSVAFFAVCD GHGGREAAQF AREHLWGFIK 120

KQKGFTSSEP AKVCAAIRKG FLACHLAMWK KLAEWPKTMT GLPSTSGTTA SVVIIRGMKM 180

YVAHVGDSGV VLGIQDDPDD FVRAVEVTQD HKPELLQERE RLGLGGSVMN KSGVNRVVWK 240

RPRLTHNGPV RRSTVIDQIP FLAVARALGD LWSYDFFSGE FVVSPEPDTS VHTLDPQKHK 300

YIILGSDGLW NMIPPQDAIS MCQDQEEKKY MMGGEHGQSC AKMLVNRALG RWRQRMLRAD 360

NTSAIVICIS PGVGSQGNFT NDDELYLNLT DSPSYNSQET SLRTPSPSST PPVKSMEEDP 420

WSRLNSKDHV PALVRSNAFS ENYLEVPAEV ARGNVQAAVL PSKDPEPLEE NCTKALTLRI 480

HDSLSNSLSV GLVPTNSTNT IMDPKNLKMS TSGQMKAQEV ERTPPANFKR TLEESNSGPL 540

MKKHKRNGLS RSNSAQPASL ATTSQRKNSV KLTMRRRLRG QKKIGNPLLH QHRKTVCVC 599

Nucleotide Sequence
(FASTA)

ATGGCGGGGC TGTACTCGCT GGGAGTGAGC GTCTTCTCCG ACCAGGGCGG GAGGAAGTAC 60

ATGGAGGACG TTACTCAGAT CGTGGTGGAG CCCGAGCCGA CCGCTGAAGA AAAGCGCTCG 120

CCTCGGCGGT CGCTCTCGCA GCCGTCACCG CCGGCTCTTC CGGGCGGCGA GGTCTCGGGG 180

AAAGGCCCAG CGGTGGGGGC CCGAGAGGCT GGCGACCCTG CCCCGGACGC GGGGGCCTCG 240

CCGGCTCCCG GCCGCTGCTG CCGCCGCCGC TCCTCGGTGG CGTTTTTTGC CGTGTGCGAT 300

GGGCACGGCG GGCGGGAGGC GGCACAGTTT GCCCGGGAGC ACTTATGGGG TTTCATCAAG 360

AAGCAGAAGG GGTTCACCTC GTCCGAGCCC GCGAAGGTTT GCGCTGCCAT CCGCAAGGGC 420

TTCCTCGCCT GTCACCTCGC CATGTGGAAG AAACTGGCAG AATGGCCAAA GACTATGACG 480

GGTCTTCCCA GCACGTCAGG GACAACGGCC AGTGTGGTCA TCATACGGGG CATGAAGATG 540

TATGTAGCTC ACGTGGGTGA CTCAGGCGTG GTTCTTGGAA TTCAGGATGA CCCAGATGAT 600

TTTGTCAGAG CTGTGGAAGT AACACAGGAC CATAAGCCAG AACTACTCCA GGAAAGAGAA 660

CGATTGGGAC TTGGTGGGAG TGTGATGAAC AAGTCTGGGG TGAATCGTGT AGTTTGGAAA 720

CGACCTCGGC TCACTCATAA TGGACCTGTT AGAAGGAGCA CAGTTATTGA CCAGATTCCT 780

TTTCTGGCAG TAGCAAGAGC ACTTGGTGAT TTGTGGAGCT ATGATTTCTT CAGTGGTGAA 840

TTTGTAGTGT CACCTGAACC AGACACAAGT GTTCACACTC TTGATCCCCA GAAGCACAAG 900

TATATTATCT TGGGGAGTGA TGGGCTTTGG AATATGATTC CACCTCAAGA TGCCATCTCA 960

ATGTGCCAGG ACCAAGAGGA GAAAAAATAC ATGATGGGTG GTGAGCATGG ACAATCTTGT 1020

GCCAAAATGC TTGTGAATCG AGCACTAGGC CGCTGGAGGC AGCGCATGCT TCGAGCAGAT 1080

AATACCAGTG CCATAGTAAT CTGCATCTCT CCAGGAGTGG GTAGTCAGGG AAATTTCACC 1140

AATGATGATG AGCTCTATCT GAACCTAACT GATAGCCCTT CCTATAATAG TCAAGAAACC 1200

AGCCTGCGGA CTCCTTCCCC AAGTTCTACA CCACCAGTCA AGTCAATGGA GGAGGACCCT 1260

TGGTCAAGGC TGAACTCTAA GGACCATGTA CCTGCCCTTG TTCGTAGTAA TGCCTTCTCA 1320

GAGAATTACT TAGAAGTCCC AGCTGAGGTA GCTCGAGGGA ATGTCCAGGC TGCAGTCTTA 1380

CCCTCAAAAG ATCCAGAGCC ACTTGAAGAA AATTGCACTA AAGCCCTGAC ATTAAGGATA 1440

CATGATTCTT TGAGTAATAG CCTGTCAGTT GGCCTGGTGC CTACCAATTC AACAAACACC 1500

ATTATGGACC CAAAAAATTT AAAGATGTCA ACTTCAGGTC AAATGAAAGC CCAAGAAGTT 1560

GAAAGAACCC CTCCAGCAAA TTTTAAAAGG ACATTAGAAG AATCCAATTC TGGCCCTCTT 1620

ATGAAGAAGC ATAAACGAAA TGGTTTAAGT CGAAGTAATA GTGCTCAGCC CGCAAGCCTC 1680

GCCACAACCT CACAGCGAAA GAACTCTGTT AAACTTACCA TGCGACGCAG ACTTAGGGGC 1740

CAGAAGAAAA TTGGAAATCC TTTACTTCAC CAGCACCGAA AAACTGTTTG TGTTTGCTGA 1800

Domain Profile

S: 4     gvvsvngrrnemedavtsspnflkspekkdr......laffgvyDGhggsevakfcsekl  57

         g vs++g+    ++a +++p++++sp+  ++      +aff+v+DGhgg+e+a+f++e+l

Q: 56    GEVSGKGPAVGAREAGDPAPDAGASPAPGRCcrrrssVAFFAVCDGHGGREAAQFAREHL  115

         6789999999999999***********99999****************************

S: 58    heilaeelesseseerkvkkalakaFlstdeel.....kvleeksldidksGstavvali  112

         + ++++++ +++se +kv++a++k+Fl+++ ++     +++++++  +++sG+ta+v++i

Q: 116   WGFIKKQKGFTSSEPAKVCAAIRKGFLACHLAMwkklaEWPKTMTGLPSTSGTTASVVII  175

         ************************************************************

S: 113   kdsklyvanvGdSravLcrngk......avelssdHkpsredEleRieeaggsvilkdga  166

         +++k+yva+vGdS++vL+ +++      ave+++dHkp+  +E+eR+   ggsv++k+g+

Q: 176   RGMKMYVAHVGDSGVVLGIQDDpddfvrAVEVTQDHKPELLQERERLG-LGGSVMNKSGV  234

         *******************8876899999*****************95.678********

S: 167   .Rv.....................lGvLavsRalGdlylk......pyvtpePevtshrl  198

          Rv                     +++Lav+RalGdl+++      ++v+peP++++h+l

Q: 235   nRVvwkrprlthngpvrrstvidqIPFLAVARALGDLWSYdffsgeFVVSPEPDTSVHTL  294

         ************************************************************

S: 199   tsede.fliLasDGlwdvvsneeavslvrdvle.....kkeaeqeaakkLvklalargsk  252

         +++++ ++iL+sDGlw+++++++a+s+++d++e      +e+ q++ak+Lv++al r+++

Q: 295   DPQKHkYIILGSDGLWNMIPPQDAISMCQDQEEkkymmGGEHGQSCAKMLVNRALGRWRQ  354

         *********************************99999899*******************

S: 253   .....dnvsaivv  260

              dn+saiv+

Q: 355   rmlraDNTSAIVI  367

         ***********97

Domain Sequence
(FASTA)

GEVSGKGPAV GAREAGDPAP DAGASPAPGR CCRRRSSVAF FAVCDGHGGR EAAQFAREHL 60

WGFIKKQKGF TSSEPAKVCA AIRKGFLACH LAMWKKLAEW PKTMTGLPST SGTTASVVII 120

RGMKMYVAHV GDSGVVLGIQ DDPDDFVRAV EVTQDHKPEL LQERERLGLG GSVMNKSGVN 180

RVVWKRPRLT HNGPVRRSTV IDQIPFLAVA RALGDLWSYD FFSGEFVVSP EPDTSVHTLD 240

PQKHKYIILG SDGLWNMIPP QDAISMCQDQ EEKKYMMGGE HGQSCAKMLV NRALGRWRQR 300

MLRADNTSAI VI 312

Keyword

Complete proteome; Hydrolase; Magnesium; Metal-binding; Protein phosphatase; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>