EKS-MYL-00483

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-MYL-00483

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
TKL/RIPK	336.8	9.0E-101	2	230	229

Status

Unreviewed

Ensembl Protein

ENSMLUP00000000560

UniProt Accession

G1NTQ4;

Protein Name

Protein Synonyms/Alias

Gene Name

RIPK2

Gene Synonyms/Alias

RIPK2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMLUG00000000618	ENSMLUP00000000560	ENSMLUT00000000618

Organism

Myotis lucifugus

Functional Description

Protein Length

478

Protein Sequence
(FASTA)

SERNDVLREA EILHKARFSY ILPILGICNE PEFLGIVTEY MPNGSLNELL HRKTEYPEVA 60

WPLRFRILHE IALGVNYLHN MNPPLLHHDL KTQNILLDNE FHVKIADFGL SKWRMMSLSQ 120

SRNSKAAPEG GTIIYMPPEN YEPGQKARAS VKHDIYSYAV IMWEVLSRKQ PFEDVTNPLQ 180

IMYSVSQGHR PDTSEESLPP STPHRARMVS LIEGGWAQNP DERPSFLKCL IELEPVLRTY 240

EEISFLEAVL QLKKTKVQSA LSAVHLCDKT SEASLNLSLN HGPQEESCGS SQCHKNSGSP 300

GTARSLCAPQ HDGLVSGKTP DLSTLLPRPA NHSWDDVSAA QTALICDHET APRSLAVHPL 360

SAEGNSERSQ PGVAQQWIQS KREDVVSQMT EACLNQALDA LLSRDLIMKE DYELISTKPT 420

RTAKVRQLLD TTDIQGEEFA RVIVQKLKDN KQMGLQPYPE ILPASRSPSL LLFHNKSL 478

Nucleotide Sequence
(FASTA)

AGTGAAAGAA ATGATGTCTT AAGAGAAGCT GAAATTTTAC ACAAAGCTAG ATTTAGTTAC 60

ATTCTTCCAA TTTTGGGAAT TTGCAATGAG CCTGAATTTT TGGGAATAGT TACTGAATAC 120

ATGCCAAATG GATCATTAAA TGAACTCCTA CATAGGAAAA CAGAATATCC GGAAGTCGCC 180

TGGCCGCTGA GATTTCGCAT CCTGCATGAA ATCGCACTGG GCGTGAACTA CCTGCATAAT 240

ATGAACCCTC CTCTACTGCA TCATGACCTG AAGACTCAGA ATATCTTACT GGATAATGAA 300

TTTCATGTTA AGATCGCAGA TTTTGGTTTA TCGAAGTGGC GCATGATGTC CCTGTCACAG 360

TCGCGGAATA GTAAGGCTGC CCCGGAAGGC GGGACCATCA TCTACATGCC GCCCGAGAAC 420

TACGAGCCGG GGCAGAAGGC GAGGGCCAGC GTCAAGCATG ACATATACAG CTATGCAGTC 480

ATCATGTGGG AAGTCTTATC CAGAAAACAG CCTTTTGAGG ATGTCACCAA CCCTTTGCAA 540

ATTATGTACA GTGTGTCACA AGGACACCGA CCCGACACCA GTGAAGAGAG CCTGCCACCT 600

AGTACCCCTC ATCGAGCGCG GATGGTCTCA CTCATCGAAG GCGGATGGGC ACAGAACCCG 660

GATGAACGGC CATCCTTCCT CAAATGTTTA ATAGAACTTG AGCCAGTCCT GAGAACATAT 720

GAAGAGATAA GTTTTCTTGA AGCTGTTTTG CAACTAAAGA AAACAAAGGT GCAGAGCGCT 780

CTGAGTGCTG TCCACTTATG TGACAAGACA TCGGAGGCAT CTCTGAACCT CTCTCTAAAT 840

CACGGTCCAC AAGAGGAATC CTGTGGATCT TCTCAGTGTC ATAAAAATAG CGGCTCTCCC 900

GGAACCGCCA GATCCCTGTG CGCTCCTCAG CACGATGGCC TTGTGTCCGG AAAAACCCCG 960

GACCTCTCCA CCCTGCTTCC CCGCCCGGCC AATCACAGCT GGGATGACGT GTCTGCGGCT 1020

CAGACGGCCC TGATCTGTGA CCACGAGACT GCCCCGCGCT CATTGGCAGT ACACCCCCTC 1080

TCCGCCGAGG GGAACTCAGA GCGATCGCAG CCTGGGGTGG CCCAGCAGTG GATCCAGAGC 1140

AAAAGGGAGG ATGTCGTGAG CCAGATGACC GAGGCCTGCC TCAACCAGGC GCTGGACGCC 1200

CTGCTGTCCC GGGACCTGAT CATGAAGGAG GACTACGAGC TCATCAGCAC CAAACCCACG 1260

AGGACCGCCA AAGTCAGGCA GTTACTGGAC ACCACTGACA TCCAGGGGGA GGAATTTGCC 1320

AGAGTCATAG TGCAGAAGCT GAAGGACAAC AAGCAGATGG GCCTCCAGCC CTACCCGGAA 1380

ATACTGCCGG CTTCTCGGTC GCCATCGTTA CTCTTATTTC ACAATAAAAG CTTATAG 1437

Domain Profile

S: 42    erkelleeakkmeklrfsyvlkllGvikeeeklglvmeymenGsLeklLkseielp...w  98

         er+++l+ea++++k+rfsy+l++lG+++e+e+lg+v+eym+nGsL++lL++++e+p   w

Q: 2     ERNDVLREAEILHKARFSYILPILGICNEPEFLGIVTEYMPNGSLNELLHRKTEYPevaW  61

         899****************************************************9999*

S: 99    plkfRilkevvlgmnyLhslkPpllhkDLkpeniLlDnelhvkiaDfGlskf.meessqs  157

         pl+fRil+e++lg+nyLh+++Ppllh+DLk++niLlDne+hvkiaDfGlsk+ m++ sqs

Q: 62    PLRFRILHEIALGVNYLHNMNPPLLHHDLKTQNILLDNEFHVKIADFGLSKWrMMSLSQS  121

         ************************************************************

S: 158   kevsssaegGtlaYlaPelleevnk.kaseksDvYsfaiviWavlakkepyeeeknslqi  216

         ++++ ++egGt++Y++Pe++e+ +k +as k+D+Ys+a+++W+vl++k+p+e+++n lqi

Q: 122   RNSKAAPEGGTIIYMPPENYEPGQKaRASVKHDIYSYAVIMWEVLSRKQPFEDVTNPLQI  181

         **********************99989*********************************

S: 217   iivvkkgnRPeleevseelPrevpq...lieLmkrcWeadpeeRPsFleie  264

         +++v++g+RP+++e  e+lP  +p+   +++L++ +W+++p+eRPsFl++

Q: 182   MYSVSQGHRPDTSE--ESLPPSTPHrarMVSLIEGGWAQNPDERPSFLKCL  230

         *************9..888888888888********************986

Domain Sequence
(FASTA)

ERNDVLREAE ILHKARFSYI LPILGICNEP EFLGIVTEYM PNGSLNELLH RKTEYPEVAW 60

PLRFRILHEI ALGVNYLHNM NPPLLHHDLK TQNILLDNEF HVKIADFGLS KWRMMSLSQS 120

RNSKAAPEGG TIIYMPPENY EPGQKARASV KHDIYSYAVI MWEVLSRKQP FEDVTNPLQI 180

MYSVSQGHRP DTSEESLPPS TPHRARMVSL IEGGWAQNPD ERPSFLKCL 229

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005622	; C:intracellular
GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0042981	; P:regulation of apoptotic process

KEGG

InterPros

IPR001315	; CARD.
IPR011029	; DEATH-like.
IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR001245	; Ser-Thr/Tyr_kinase_cat_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00619	; CARD; 1.
PF07714	; Pkinase_Tyr; 1.

SMARTs

SM00114

; CARD; 1.

Prosites

PS50209	; CARD; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013