EKS-MYL-00429

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-MYL-00429

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/ULK	309.3	2.5E-92	4	244	241

Status

Unreviewed

Ensembl Protein

ENSMLUP00000001402

UniProt Accession

G1NVT6;

Protein Name

Protein Synonyms/Alias

Gene Name

STK36

Gene Synonyms/Alias

STK36;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMLUG00000001524	ENSMLUP00000001402	ENSMLUT00000001527

Organism

Myotis lucifugus

Functional Description

Protein Length

1313

Protein Sequence
(FASTA)

MEKYHVLEMI GEGSFGRVYK GRRKYSAQVV ALKFIPKLGR SEKELRNLQR EIEIMRGLRH 60

PNIVHMLDSF ETDKEVVVVT DYAEGELFQI LEDDGKLPED QVQAIAAQLV SALYYLHSHR 120

ILHRDMKPQN ILLAKDGGIK LCDFGFARAM STNTMVLTSI KGTPLYMSPE LVEERPYDHT 180

ADLWSVGCIL YELAVGTPPF YTTSIFQLVN LILKDPVRWP PTISPCFKNF LQGLLTKDPR 240

QQLHHPFIAG FIAGRVTIIT EPAGPDLGTP LTSRLPPELQ VLKDQQAHQL APKGNRSRIL 300

RQARKLMAEE AKQKKHQNTG PTLEQEDRTI KVVTGTTPVP PPQEPGLLAG IMASEMKSSW 360

AEWGAGEAPP APRENWITED SERAFPELRP EQSQAGQQST GAVDLENEEP DSDDEWQHLL 420

ETMEPVPIQL KTPLTLLCNP DFCQRIQSQL HEAGGQILKD MLEGASCILP ALRVLSNLLT 480

SCSDSVPLYV FCREAGLPGL LLRLLRHSQE SHSIQQQCWY GTFLRDLMAV IQAYFACTFN 540

LERSQTGDSL QVFQEAADLF LDLLGKLLAQ PDDSKQTLQR DSLMCFTVLC EAMDGNSCAI 600

SKAFYSSLLT TQRAVLDGLL RGLTVPQLPF HTPPGAPQVS QPLKEQSEDL PGAISSALAA 660

ICIVPLGLPG CWEAKEQISR HLANQLTEDN NQLRPSLICG LQHPILCLHL LKVLYSCCHV 720

SERLCRRLGQ EPLALKSLLM LVQGKIKVVD WEESTEVTLY LLSLLVLRLQ DLPSGMEKLG 780

SETATLFTHS HVVSLVSAAA CLLGQLGQQG VTFDLQPVEW IPAATHALCA PAEVRLTPPD 840

GCGFYDGLLT LLLQLLTQEG KANLIRDMVS SEMWTVLWHR FSMALRLSKE VSTQEEELTL 900

SSPHSSSSEP DWTLISPQGV AAMLSLAVAT FTQEPQLCLS HLSQHGSILM STLKHLLSPS 960

FLQQLGQAPH GSEFLPVVVL SVCQLLCFPF ALDVDADLLG GILANLTDSA VTAHLLQVCC 1020

HHLLLPQVEL PISLLTHLAL RDPTSLNQFV NTVAASPGTI ISFLSVALLG DQPLLTSDLL 1080

SLLAHTARVL PPSHLSFIQE LLAGSDESYR PLRSLLGHPE NCVRARIYGL LGHLLQHSMA 1140

LRGALQSQAG LLSLLLLGLG DKDPAVRRSA SFAVGNAAYQ AGPLGPALAA AVPCMTQLLG 1200

DPQAGIRRHA VSALGNLGSE GLGEELLQCQ VPQRLLEMAC GDPQPHVKEA ALIALRSLSQ 1260

EPCIHQVLVS LGASEKLALL SLGNQLLPHS SPRPASAKLC MKLIHLLRPA HST 1313

Nucleotide Sequence
(FASTA)

ATGGAAAAGT ACCACGTGTT GGAGATGATT GGAGAAGGCT CTTTTGGGCG GGTGTACAAG 60

GGTCGGAGGA AATACAGTGC TCAGGTGGTG GCCCTGAAGT TCATTCCAAA ATTGGGACGC 120

TCAGAGAAAG AGCTGAGGAA TCTGCAACGA GAGATTGAAA TCATGCGGGG CCTGCGGCAT 180

CCCAACATTG TGCACATGCT CGACAGTTTT GAGACTGATA AAGAGGTAGT GGTAGTGACA 240

GACTATGCTG AGGGAGAGCT CTTTCAGATC CTGGAAGATG ATGGAAAACT TCCTGAAGAC 300

CAGGTTCAAG CCATTGCTGC CCAGTTGGTG TCGGCCCTGT ATTATCTGCA TTCCCACCGT 360

ATCCTTCACC GAGACATGAA GCCTCAGAAC ATCCTCCTTG CCAAGGATGG TGGCATCAAG 420

CTCTGTGACT TTGGATTTGC CCGGGCTATG AGCACCAACA CAATGGTGCT AACATCCATC 480

AAAGGCACAC CACTCTATAT GTCCCCAGAA CTGGTGGAAG AGCGACCATA CGACCACACC 540

GCAGACCTCT GGTCTGTGGG CTGCATACTT TATGAGCTGG CTGTAGGCAC CCCTCCCTTC 600

TATACCACAA GCATCTTTCA ACTGGTCAAC CTCATTCTCA AGGACCCTGT GCGCTGGCCC 660

CCAACCATTA GTCCTTGCTT CAAGAACTTC CTGCAGGGAC TGCTCACCAA AGACCCCCGG 720

CAGCAGTTAC ATCACCCCTT TATTGCTGGC TTTATTGCTG GCCGTGTCAC CATAATAACT 780

GAACCAGCAG GTCCAGATTT GGGCACCCCA TTAACCAGTC GTCTACCTCC AGAACTTCAG 840

GTCCTCAAGG ACCAACAGGC ACATCAACTG GCCCCCAAGG GCAATCGATC TCGCATCTTG 900

CGTCAAGCCC GTAAGCTCAT GGCTGAGGAG GCCAAGCAGA AGAAACACCA GAATACAGGA 960

CCTACCCTGG AACAGGAAGA CAGGACCATC AAGGTGGTTA CTGGCACGAC CCCTGTGCCC 1020

CCTCCTCAGG AACCAGGCCT CTTGGCTGGG ATCATGGCCT CAGAAATGAA GAGCAGCTGG 1080

GCTGAGTGGG GGGCTGGAGA AGCCCCCCCT GCACCTCGGG AAAACTGGAT CACTGAGGAT 1140

AGTGAACGAG CATTCCCAGA GCTGAGGCCA GAGCAGTCAC AGGCCGGCCA GCAGAGCACT 1200

GGTGCAGTAG ACCTAGAAAA TGAGGAGCCA GACAGTGATG ATGAGTGGCA ACACCTGCTA 1260

GAGACCATGG AGCCTGTGCC CATCCAGCTG AAGACCCCTC TCACCCTGCT GTGCAATCCA 1320

GACTTTTGCC AGCGCATCCA GAGTCAGCTA CATGAGGCTG GAGGGCAGAT CCTGAAAGAC 1380

ATGCTGGAGG GTGCGTCCTG TATCCTCCCT GCACTCCGGG TCCTGAGCAA TCTTCTGACC 1440

AGCTGCAGTG ACTCTGTTCC CTTGTATGTC TTCTGCCGTG AGGCAGGGCT CCCTGGGCTG 1500

CTGCTCAGGC TACTCAGACA CAGCCAGGAG AGCCACAGTA TTCAGCAGCA ATGTTGGTAT 1560

GGGACCTTCT TACGGGACCT GATGGCCGTG ATTCAGGCCT ACTTTGCCTG CACCTTTAAT 1620

CTGGAGAGGA GCCAGACAGG TGACAGCCTA CAGGTATTTC AAGAAGCTGC CGACCTCTTT 1680

CTGGACCTGT TGGGGAAACT TCTGGCCCAA CCAGATGACT CCAAGCAGAC TTTACAGAGG 1740

GATAGCCTTA TGTGCTTCAC TGTTCTGTGT GAAGCCATGG ATGGGAATAG CTGTGCCATC 1800

TCCAAAGCCT TTTACTCCAG TCTGCTGACT ACACAGCGGG CCGTGTTGGA CGGGCTCCTT 1860

CGTGGCTTGA CAGTCCCACA GCTCCCTTTT CACACACCCC CAGGAGCCCC TCAAGTGAGC 1920

CAGCCACTGA AGGAGCAGAG TGAGGATCTG CCTGGAGCCA TTTCCTCTGC GCTGGCAGCC 1980

ATATGCATTG TTCCTCTAGG GCTGCCTGGC TGCTGGGAAG CCAAGGAACA GATCTCTCGG 2040

CATTTGGCAA ATCAGCTCAC TGAAGACAAC AACCAACTGA GGCCATCTCT CATCTGTGGT 2100

CTGCAGCATC CCATCCTGTG CCTACACCTT CTTAAGGTTC TCTACTCCTG CTGCCATGTT 2160

AGTGAACGCC TGTGCCGCCG TTTAGGGCAA GAGCCCCTGG CCTTGAAGTC ATTGTTGATG 2220

TTGGTCCAGG GCAAGATAAA GGTAGTGGAT TGGGAAGAGT CTACTGAAGT GACACTCTAC 2280

CTCCTCTCCC TTCTTGTCCT TCGGCTCCAA GATCTGCCTT CTGGAATGGA GAAGCTGGGC 2340

AGTGAGACTG CTACTCTCTT TACCCATTCA CACGTCGTCT CTCTTGTGAG TGCAGCGGCG 2400

TGTTTACTGG GACAGCTTGG ACAGCAAGGG GTGACCTTTG ACCTCCAGCC TGTGGAGTGG 2460

ATCCCTGCAG CCACTCATGC CCTGTGTGCC CCTGCTGAGG TCCGGTTGAC TCCACCTGAT 2520

GGCTGTGGGT TCTATGACGG CCTACTCACC CTTCTGTTGC AGCTCCTCAC CCAGGAGGGG 2580

AAAGCTAACC TGATAAGGGA CATGGTTAGC TCAGAAATGT GGACCGTTCT GTGGCACCGC 2640

TTCTCCATGG CACTGAGGCT CTCCAAGGAG GTATCTACAC AGGAAGAGGA GCTAACGCTG 2700

TCCAGTCCAC ATAGCTCAAG CTCAGAGCCA GACTGGACAC TGATCTCTCC CCAAGGTGTG 2760

GCAGCCATGC TGAGCCTGGC CGTGGCCACC TTTACCCAGG AGCCCCAGTT ATGCCTGAGC 2820

CACCTGTCTC AGCATGGAAG TATCCTCATG TCCACCTTGA AGCATCTGCT TTCCCCCAGC 2880

TTCCTACAGC AGCTGGGCCA GGCGCCTCAC GGGTCTGAGT TTCTCCCCGT CGTGGTGCTC 2940

TCTGTCTGCC AGCTCCTCTG CTTCCCCTTT GCCCTGGATG TGGATGCTGA CCTCCTTGGG 3000

GGTATCTTGG CTAACCTAAC AGACTCAGCA GTCACAGCCC ACCTGCTGCA GGTCTGCTGT 3060

CACCATCTCC TGTTGCCACA AGTGGAGCTG CCCATCAGTC TCCTCACACA CCTGGCCCTC 3120

AGGGATCCCA CCTCTCTCAA CCAGTTTGTG AACACAGTGG CTGCCTCCCC TGGAACCATC 3180

ATCTCATTCC TCTCAGTTGC CCTTCTAGGT GACCAGCCGC TGCTGACCTC TGACCTTCTC 3240

TCTCTGTTGG CCCACACAGC CCGGGTTCTG CCTCCCAGTC ACTTGTCCTT TATCCAAGAA 3300

CTCCTTGCTG GCTCCGATGA ATCCTATAGG CCCCTGCGTA GCCTCTTGGG TCACCCAGAG 3360

AATTGTGTGC GGGCCCGCAT TTATGGGCTC CTGGGACATT TGCTCCAACA CAGCATGGCC 3420

CTGCGTGGGG CACTGCAGAG CCAGGCTGGA CTGCTCAGCC TTCTGCTGCT GGGGCTTGGA 3480

GACAAGGACC CTGCTGTGCG GCGCAGTGCC AGCTTTGCTG TGGGCAATGC AGCCTATCAA 3540

GCCGGTCCCC TGGGGCCTGC CCTGGCAGCT GCAGTACCCT GTATGACCCA GCTGCTTGGA 3600

GATCCTCAGG CTGGTATCCG GCGCCATGCT GTGTCAGCTC TGGGCAACTT GGGATCTGAG 3660

GGGTTGGGAG AAGAGCTGTT ACAGTGTCAA GTACCCCAGC GGCTGCTAGA GATGGCGTGT 3720

GGAGACCCCC AGCCACATGT GAAGGAGGCC GCCCTCATTG CCCTTCGGAG CCTCAGCCAG 3780

GAGCCCTGTA TCCATCAGGT GCTGGTGTCC CTGGGTGCCA GTGAGAAATT AGCCTTGCTC 3840

TCTCTGGGGA ATCAGTTACT GCCGCACAGC AGTCCCAGGC CTGCCTCTGC CAAACTCTGC 3900

ATGAAACTCA TTCATCTCCT GAGACCAGCC CACAGCACG 3939

Domain Profile

S: 1     ysleeeiGkGsfavvykgrlrkktsqvvAikvvekkkl.kkslenlekeikilkelkhen  59

         y++ e+iG+Gsf+ vykgr rk ++qvvA+k++ k ++ +k+l+nl++ei+i++ l+h+n

Q: 4     YHVLEMIGEGSFGRVYKGR-RKYSAQVVALKFIPKLGRsEKELRNLQREIEIMRGLRHPN  62

         8999***************.******************9*********************

S: 60    ivalldveetskevylvmeycaggdLakllkqkkeLsedtvreflqqlasalkaLhskki  119

         iv++ld++et+kev++v++y++ g+L ++l+++++L+ed+v+++++ql+sal++Lhs++i

Q: 63    IVHMLDSFETDKEVVVVTDYAE-GELFQILEDDGKLPEDQVQAIAAQLVSALYYLHSHRI  121

         **********************.*************************************

S: 120   vhrDlkPqniLlsyadakkelkkvtlkladFglarvlkeesma.atlkGsplYmaPEvvk  178

         +hrD+kPqniLl+        k++++kl+dFg+ar++++++m  +++kG+plYm+PE+v+

Q: 122   LHRDMKPQNILLA--------KDGGIKLCDFGFARAMSTNTMVlTSIKGTPLYMSPELVE  173

         *************........89********************9****************

S: 179   eqqydakaDlWSiGtilyellvGkpPfaaesiseLvekiekndvleppipkeisselkdl  238

         e+ yd++aDlWS+G+ilyel+vG+pPf+++si++Lv+ i k++v   ++p +is+++k++

Q: 174   ERPYDHTADLWSVGCILYELAVGTPPFYTTSIFQLVNLILKDPV---RWPPTISPCFKNF  230

         ********************************************...*************

S: 239   lqsLLqrdpkkRis  252

         lq+LL++dp++ +

Q: 231   LQGLLTKDPRQQLH  244

         **********9875

Domain Sequence
(FASTA)

YHVLEMIGEG SFGRVYKGRR KYSAQVVALK FIPKLGRSEK ELRNLQREIE IMRGLRHPNI 60

VHMLDSFETD KEVVVVTDYA EGELFQILED DGKLPEDQVQ AIAAQLVSAL YYLHSHRILH 120

RDMKPQNILL AKDGGIKLCD FGFARAMSTN TMVLTSIKGT PLYMSPELVE ERPYDHTADL 180

WSVGCILYEL AVGTPPFYTT SIFQLVNLIL KDPVRWPPTI SPCFKNFLQG LLTKDPRQQL 240

H 241

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011989	; ARM-like.
IPR016024	; ARM-type_fold.
IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013