EKS-MYL-00226

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-MYL-00226

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
STE/STE7	392.6	8.6E-118	64	329	266

Status

Unreviewed

Ensembl Protein

ENSMLUP00000001837

UniProt Accession

G1NWW3;

Protein Name

Protein Synonyms/Alias

Gene Name

MAP2K4

Gene Synonyms/Alias

MAP2K4;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMLUG00000002023	ENSMLUP00000001837	ENSMLUT00000002018

Organism

Myotis lucifugus

Functional Description

Protein Length

361

Protein Sequence
(FASTA)

GKRKALKLNF ANPPFKSTAR FTLNPNPTGV QNPHIERLRT HSIESSGKLK ISPEQHWDFT 60

AEDLKDLGEI GRGAYGSVNK MVHKPSGQIM AVKRIRSTVD EKEQKQLLMD LDVVMRSSDC 120

PYIVQFYGAL FREGDCWICM ELMSTSFDKF YKYVYSVLDD VIPEEILGKI TLATVKALNH 180

LKENLKIIHR DIKPSNILLD RSGNIKLCDF GISGQLVDSI AKTRDAGCRP YMAPERIDPS 240

ASRQGYDVRS DVWSLGITLY ELATGRFPYP KWNSVFDQLT QVVKGDPPQL SNSEEREFSP 300

SFINFVNLCL TKDESKRPKY KELLKHPFIL MYEERTVEVA SYVCKILDQM PATPSSPMYV 360

D 361

Nucleotide Sequence
(FASTA)

GGTAAACGCA AAGCACTGAA GTTGAATTTT GCAAATCCAC CTTTCAAATC TACAGCAAGG 60

TTTACTCTGA ATCCCAATCC TACAGGAGTT CAAAACCCAC ACATAGAGAG ACTGAGAACA 120

CACAGCATTG AATCGTCAGG AAAACTGAAG ATCTCCCCTG AACAGCACTG GGATTTCACC 180

GCAGAGGACT TGAAAGACCT GGGAGAAATC GGACGAGGAG CGTATGGTTC TGTCAACAAA 240

ATGGTCCACA AACCAAGTGG ACAAATAATG GCAGTTAAAA GAATTCGGTC AACAGTGGAT 300

GAAAAAGAAC AAAAGCAACT TCTTATGGAT TTGGATGTAG TAATGCGGAG TAGTGATTGC 360

CCATACATTG TTCAGTTTTA TGGTGCACTC TTCAGAGAGG GTGACTGTTG GATCTGTATG 420

GAACTCATGT CTACCTCGTT TGATAAGTTT TACAAATATG TATATAGTGT ATTAGATGAT 480

GTTATTCCAG AAGAAATTTT AGGCAAAATC ACTTTAGCAA CTGTGAAAGC ACTAAACCAC 540

TTAAAGGAAA ACTTGAAAAT CATTCACAGA GATATCAAAC CTTCCAATAT CCTTCTGGAC 600

AGAAGTGGAA ATATTAAACT CTGTGACTTT GGCATCAGCG GACAGCTTGT GGACTCTATT 660

GCCAAGACCA GAGATGCTGG GTGTAGGCCG TACATGGCAC CGGAAAGAAT AGACCCAAGT 720

GCATCACGAC AAGGCTATGA TGTCCGCTCT GATGTCTGGA GTTTGGGGAT CACGTTGTAC 780

GAGTTGGCCA CAGGCCGATT TCCTTATCCA AAGTGGAATA GTGTATTTGA TCAACTAACG 840

CAAGTTGTGA AAGGAGACCC CCCGCAGCTG AGTAATTCGG AGGAAAGGGA ATTCTCCCCG 900

AGTTTCATCA ATTTTGTCAA CTTGTGCCTT ACAAAGGACG AATCCAAAAG GCCAAAGTAT 960

AAAGAACTTC TGAAACATCC CTTTATTTTA ATGTATGAAG AACGTACTGT AGAGGTCGCA 1020

AGCTATGTTT GTAAAATCCT GGATCAAATG CCAGCAACTC CCAGCTCTCC CATGTATGTC 1080

GATTGA 1086

Domain Profile

S: 1     lekleelGaGnggvVekvlhkksgkilavKtirleikkeeqkqilrelevlkkssnspyi  60

         l++l+e+G+G++g+V+k++hk+sg+i+avK+ir++++++eqkq+l++l+v+++ss++pyi

Q: 64    LKDLGEIGRGAYGSVNKMVHKPSGQIMAVKRIRSTVDEKEQKQLLMDLDVVMRSSDCPYI  123

         68899*******************************************************

S: 61    vkfyGafvsegdvsicmelmdgtsldkvlkkvlek.kkripekvlgkiavavvkaleylk  119

         v+fyGa+++egd++icmelm+ ts+dk++k v+++ ++ ipe++lgki++a+vkal++lk

Q: 124   VQFYGALFREGDCWICMELMS-TSFDKFYKYVYSVlDDVIPEEILGKITLATVKALNHLK  182

         *********************.*************9************************

S: 120   eklkiiHRDvKPsNiLvnskGevKlCDFGvsgqlvdsiAksa.vGtksYmaPErieg...  175

         e+lkiiHRD+KPsNiL++++G++KlCDFG+sgqlvdsiAk++ +G+++YmaPEri++

Q: 183   ENLKIIHRDIKPSNILLDRSGNIKLCDFGISGQLVDSIAKTRdAGCRPYMAPERIDPsas  242

         *********************************************************999

S: 176   kkkYsvksdvWslGltlvelatgrypyeklkeilellkaivneeppklpee...efseef  232

         ++ Y+v+sdvWslG+tl+elatgr+py+k+++ +++l+++v+++pp+l+++   efs++f

Q: 243   RQGYDVRSDVWSLGITLYELATGRFPYPKWNSVFDQLTQVVKGDPPQLSNSeerEFSPSF  302

         9***********************************************988788******

S: 233   qefvskClkkdekeRpklkellkhafi  259

         ++fv+ Cl+kde++Rpk+kellkh+fi

Q: 303   INFVNLCLTKDESKRPKYKELLKHPFI  329

         **************************7

Domain Sequence
(FASTA)

LKDLGEIGRG AYGSVNKMVH KPSGQIMAVK RIRSTVDEKE QKQLLMDLDV VMRSSDCPYI 60

VQFYGALFRE GDCWICMELM STSFDKFYKY VYSVLDDVIP EEILGKITLA TVKALNHLKE 120

NLKIIHRDIK PSNILLDRSG NIKLCDFGIS GQLVDSIAKT RDAGCRPYMA PERIDPSASR 180

QGYDVRSDVW SLGITLYELA TGRFPYPKWN SVFDQLTQVV KGDPPQLSNS EEREFSPSFI 240

NFVNLCLTKD ESKRPKYKEL LKHPFI 266

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013