EKS-MYL-00061

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-MYL-00061

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDK	389.5	8.4E-117	192	473	282

Status

Unreviewed

Ensembl Protein

ENSMLUP00000002190

UniProt Accession

G1NXS7;

Protein Name

Protein Synonyms/Alias

Gene Name

CDK17

Gene Synonyms/Alias

CDK17;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMLUG00000002405	ENSMLUP00000002190	ENSMLUT00000002410

Organism

Myotis lucifugus

Functional Description

Protein Length

523

Protein Sequence
(FASTA)

MKKFKRRLSL TLRGSQTIDE SLSELAEQMT IEENSSKDNE PIVKNGRPPT SHSMHSFLHQ 60

YTGSFKKPPL RRPHSVIGGS LGSFMAMPRN GSRLDIVHEN LKMGSDGESD QASGTSSDEV 120

QSPTGVCLRN RIHRRISMED LNKRLSLPAD IRIPDGYLEK FQINSPPFDQ PMSRRSRRAS 180

LSEIGFGKME TYIKLEKLGE GTYATVYKGR SKLTENLVAL KEIRLEHEEG APCTAIREVS 240

LLKDLKHANI VTLHDIVHTD KSLTLVFEYL DKDLKQYMDD CGNIMSMHNV KLFLYQILRG 300

LAYCHRRKVL HRDLKPQNLL INEKGELKLA DFGLARAKSV PTKTYSNEVV TLWYRPPDVL 360

LGSSEYSTQI DMWGVGCIFF EMASGRPLFP GSTVEDELHL IFRLLGTPSQ ETWPGVSSND 420

EFKNYNFPKY KPQPLINHAP RLDSEGIELI TKFLQYESKK RVPAEEAMKH VYFRSLGPRI 480

HALPESVSIF SLKEIQLQKD PGFRNSSYPE TDTRKLKHQN YLF 523

Nucleotide Sequence
(FASTA)

ATGAAAAAAT TTAAGAGAAG GCTATCCCTC ACACTTCGAG GAAGCCAGAC TATTGACGAA 60

TCATTGTCTG AATTGGCTGA ACAAATGACT ATTGAAGAAA ATAGCAGCAA GGATAATGAG 120

CCTATTGTGA AGAATGGCAG GCCTCCAACC TCTCACAGCA TGCATTCCTT CCTACACCAG 180

TACACAGGGT CCTTCAAGAA GCCCCCATTG CGGAGACCAC ATAGTGTTAT TGGAGGAAGC 240

CTTGGCTCCT TCATGGCAAT GCCCAGAAAT GGAAGCAGAT TAGATATTGT TCATGAAAAT 300

CTAAAAATGG GATCAGATGG TGAGAGTGAC CAAGCTTCTG GGACATCATC TGATGAAGTC 360

CAATCACCTA CAGGTGTTTG TCTTAGAAAT CGTATACATA GACGGATCTC AATGGAGGAT 420

TTAAATAAAC GGTTATCACT GCCTGCAGAT ATCAGAATAC CTGATGGATA TCTTGAAAAG 480

TTTCAGATAA ACAGTCCACC GTTTGACCAA CCAATGAGCC GAAGATCTCG TAGAGCTTCC 540

TTATCAGAAA TTGGGTTTGG GAAAATGGAA ACCTACATCA AATTGGAGAA GCTTGGAGAG 600

GGTACATATG CTACAGTATA TAAAGGGAGA AGTAAATTGA CAGAGAATTT GGTGGCATTA 660

AAAGAGATCC GATTGGAACA CGAAGAAGGT GCACCCTGCA CAGCGATAAG AGAAGTTTCA 720

CTGTTAAAGG ATCTAAAACA TGCAAATATA GTTACCTTAC ATGACATTGT TCACACAGAT 780

AAATCTTTGA CTCTGGTGTT TGAGTATCTG GATAAAGACT TAAAACAGTA CATGGATGAT 840

TGTGGAAACA TCATGAGTAT GCACAATGTG AAGCTGTTTT TATACCAAAT TCTACGTGGT 900

TTGGCATATT GCCACAGAAG GAAAGTGTTG CACCGAGACT TGAAACCACA GAACCTCCTC 960

ATTAATGAAA AAGGAGAACT AAAGCTAGCC GATTTTGGAC TAGCCAGAGC CAAGTCAGTT 1020

CCCACAAAGA CCTACTCAAA TGAAGTTGTC ACACTATGGT ACCGGCCACC TGATGTGCTT 1080

CTCGGTTCCT CAGAGTACTC AACACAGATT GACATGTGGG GTGTTGGTTG CATTTTCTTT 1140

GAAATGGCTT CTGGAAGACC TCTGTTTCCA GGATCAACTG TGGAAGATGA ACTGCACTTA 1200

ATTTTCCGAC TGCTAGGGAC TCCATCTCAG GAAACTTGGC CAGGTGTTTC TTCAAATGAT 1260

GAGTTCAAGA ACTACAACTT CCCAAAATAT AAACCACAAC CTCTAATTAA CCATGCACCC 1320

AGGTTAGACT CTGAAGGAAT CGAATTGATA ACAAAATTTC TTCAGTATGA ATCTAAGAAA 1380

AGAGTTCCAG CAGAAGAAGC CATGAAACAT GTGTACTTTC GAAGTCTGGG ACCAAGGATA 1440

CATGCCTTAC CTGAAAGTGT ATCAATATTC AGTTTGAAAG AGATTCAGTT GCAAAAGGAC 1500

CCAGGTTTTC GAAATTCTTC TTATCCAGAG ACAGATACCA GAAAATTAAA GCACCAAAAT 1560

TATTTATTT 1569

Domain Profile

S: 1     yeklekigeGtygkvykakdketgevvAlKkirlekekegvpitalrEisllkelkhkni  60

         y klek+geGty++vyk+++k t+++vAlK+irle+e eg p+ta+rE+sllk+lkh+ni

Q: 192   YIKLEKLGEGTYATVYKGRSKLTENLVALKEIRLEHE-EGAPCTAIREVSLLKDLKHANI  250

         7799********************************9.9*********************

S: 61    vkLlevvakdkkklyLvfefleqdLkkllkkkkkkklsleevkslllqlleglaylHsnk  120

         v+L+++v+ ++k+l+Lvfe+l++dLk++++++ +  +s+++vk +l+q+l+glay+H++k

Q: 251   VTLHDIVH-TDKSLTLVFEYLDKDLKQYMDDCGN-IMSMHNVKLFLYQILRGLAYCHRRK  308

         ********.99***********************.*************************

S: 121   ilHRDlKpqNlLiskegklklaDfGlarafssplktytkevvTlwYraPelLlgakeYst  180

         +lHRDlKpqNlLi+++g+lklaDfGlara s+p+kty++evvTlwYr+P++Llg++eYst

Q: 309   VLHRDLKPQNLLINEKGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSSEYST  368

         ************************************************************

S: 181   avDiWsvgcilaelltrkplfqgkseidqlerifkllgtpsekvwpevsklpeyk.ksfp  239

         ++D+W+vgci+ e+++ +plf+g++  d+l+ if+llgtps+++wp+vs+  e+k ++fp

Q: 369   QIDMWGVGCIFFEMASGRPLFPGSTVEDELHLIFRLLGTPSQETWPGVSSNDEFKnYNFP  428

         *******************************************************99***

S: 240   kkkkkklkekvkklkekaldllekllaldpkkRisakealqhkyf  284

         k+k++ l ++ ++l++++++l++k+l+++ kkR+ a+ea++h yf

Q: 429   KYKPQPLINHAPRLDSEGIELITKFLQYESKKRVPAEEAMKHVYF  473

         ********************************************8

Domain Sequence
(FASTA)

YIKLEKLGEG TYATVYKGRS KLTENLVALK EIRLEHEEGA PCTAIREVSL LKDLKHANIV 60

TLHDIVHTDK SLTLVFEYLD KDLKQYMDDC GNIMSMHNVK LFLYQILRGL AYCHRRKVLH 120

RDLKPQNLLI NEKGELKLAD FGLARAKSVP TKTYSNEVVT LWYRPPDVLL GSSEYSTQID 180

MWGVGCIFFE MASGRPLFPG STVEDELHLI FRLLGTPSQE TWPGVSSNDE FKNYNFPKYK 240

PQPLINHAPR LDSEGIELIT KFLQYESKKR VPAEEAMKHV YF 282

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013