EKS-MYL-00247

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-MYL-00247

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/CAMKL	325.4	2.2E-97	1	240	240

Status

Unreviewed

Ensembl Protein

ENSMLUP00000002961

UniProt Accession

G1NZQ9;

Protein Name

Protein Synonyms/Alias

Gene Name

BRSK1

Gene Synonyms/Alias

BRSK1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMLUG00000003247	ENSMLUP00000002961	ENSMLUT00000003257

Organism

Myotis lucifugus

Functional Description

Protein Length

736

Protein Sequence
(FASTA)

GLVKLGVHCI TGQKVAIKIV NREKLSESVL MKVEREIAIL KLIEHPHVLK LHDVYENKKY 60

LYLVLEHVSG GELFDYLVKK GRLTPKEARK FFRQIVSALD FCHSYSICHR DLKPENLLLD 120

EKNNIRIADF GMASLQVGDS LLETSCGSPH YACPEVIKGE KYDGRRADMW SCGVILFALL 180

VGALPFDDDN LRQLLEKVKR GVFHMPHFIP PDCQSLLRGM IEVEPEKRLS LEQIQKHPWY 240

LGGKHEPDPC LEPTPGRRVA MRSLPSNGEL DPDVLESMAS LGCFRDRERL HRELRSEEEN 300

QEKMIYYLLL DRKERYPSCE DQDLPPRNDV DPPRKRVDSP MLSRHGKRRP ERKSMEVLSI 360

TDAGGGGSPV PTRRALEMAQ HSQRNRSRSV SGASTGLSSS PLSSPRSPVF SFSPEPGAGD 420

EARGGGSPTS KTQTLPSRGP RGGGAGEQPP PPSARSTPLP GPPGSPRSSG GTPLHSPLHT 480

PRASPTGTPG TTPPPSPGGG VGGAAWRSRL NSIRNSFLGS PRFHRRKMQV PTAEEMSSLT 540

PESSPELAKR SWFGNFISLD KEEQIFLVLK DKPLSSIKAD IVHAFLSIPS LSHSVLSQTS 600

FRAEYKASGG PSVFQKPVRF QVDISSSEGP EPSPRRDGGG GGGGVYSVTF TLLSGPSRRF 660

KRVVETIQAQ LLSTHDQPSV QALTDEKNGA QTRPASTPPR SLQPPPGRPD PELTSSPRRG 720

PPKDKKLLAT NGTPLP 736

Nucleotide Sequence
(FASTA)

GGGCTGGTTA AGCTGGGCGT CCACTGCATC ACGGGCCAGA AGGTCGCCAT CAAGATCGTG 60

AACCGGGAGA AGCTGTCGGA ATCGGTGCTG ATGAAGGTGG AGCGGGAGAT CGCCATCCTG 120

AAGCTCATCG AACACCCACA CGTCCTCAAG CTGCACGACG TCTACGAGAA CAAGAAATAT 180

TTATACCTGG TTCTGGAGCA TGTCTCTGGA GGTGAGCTGT TTGACTACCT GGTAAAAAAG 240

GGGAGACTGA CCCCCAAGGA GGCCCGGAAG TTCTTCCGCC AGATCGTGTC AGCGCTGGAC 300

TTCTGCCACA GCTATTCCAT CTGCCACAGA GACCTGAAGC CGGAGAACCT GCTGCTGGAC 360

GAGAAGAACA ACATCCGCAT CGCGGACTTC GGCATGGCGT CCCTGCAGGT GGGGGACAGC 420

CTCCTGGAGA CCAGCTGCGG GTCCCCGCAC TATGCGTGTC CGGAGGTGAT TAAGGGGGAG 480

AAGTACGACG GCCGCAGGGC GGACATGTGG AGCTGCGGGG TCATCCTCTT CGCCCTGCTG 540

GTGGGGGCTC TGCCCTTCGA TGATGACAAC CTCCGCCAGC TGCTGGAGAA GGTGAAACGG 600

GGTGTCTTCC ACATGCCCCA CTTCATCCCG CCCGACTGCC AGAGCCTCCT GCGGGGCATG 660

ATCGAGGTGG AGCCCGAGAA GAGGCTCAGT CTGGAGCAAA TCCAGAAACA TCCTTGGTAC 720

CTGGGTGGGA AACATGAGCC GGACCCGTGC TTGGAGCCGA CCCCTGGCCG CAGGGTGGCC 780

ATGCGGAGTC TGCCGTCCAA CGGGGAGCTG GACCCCGACG TCCTGGAGAG CATGGCTTCG 840

CTGGGCTGCT TCAGGGACCG GGAGCGGCTG CACCGCGAGC TGCGCAGCGA GGAGGAGAAC 900

CAAGAAAAAA TGATCTATTA TCTGCTTTTG GATCGGAAGG AGCGGTACCC CAGCTGTGAG 960

GACCAGGACC TGCCTCCCCG CAATGATGTT GACCCCCCTC GGAAGCGAGT GGACTCCCCC 1020

ATGCTGAGCC GGCACGGGAA ACGGCGGCCA GAGCGGAAGT CCATGGAAGT CCTGAGCATC 1080

ACGGATGCGG GCGGCGGCGG CTCCCCGGTG CCCACCCGGC GGGCCCTGGA GATGGCCCAG 1140

CACAGTCAGA GAAACAGATC CCGTAGCGTC AGTGGAGCCT CCACCGGCCT GTCCTCCAGC 1200

CCTCTGAGCA GTCCGCGGAG TCCGGTCTTT TCCTTCTCAC CGGAGCCTGG GGCTGGAGAT 1260

GAGGCTCGGG GAGGAGGCTC CCCGACTTCC AAAACGCAGA CGCTGCCTTC TCGAGGCCCC 1320

AGGGGTGGGG GCGCCGGGGA GCAGCCCCCA CCCCCCAGTG CCCGCTCCAC TCCCCTGCCT 1380

GGACCCCCAG GCTCCCCACG TTCCTCCGGG GGGACCCCCT TGCACTCGCC TCTGCACACT 1440

CCCCGGGCCA GCCCCACCGG GACCCCGGGG ACGACGCCGC CTCCAAGCCC AGGCGGTGGT 1500

GTCGGGGGAG CCGCCTGGAG GAGTCGTCTC AACTCCATCC GCAACAGCTT CCTGGGCTCC 1560

CCTCGTTTCC ACCGGCGCAA GATGCAGGTG CCCACCGCCG AGGAGATGTC CAGTTTGACG 1620

CCGGAGTCCT CTCCAGAGCT GGCAAAACGC TCCTGGTTCG GGAACTTCAT CTCCTTGGAC 1680

AAAGAAGAAC AAATTTTTCT CGTGCTAAAG GACAAACCTC TCAGTAGCAT CAAAGCGGAC 1740

ATCGTCCATG CCTTCCTGTC GATCCCCAGC CTGAGTCACA GCGTGCTGTC ACAGACCAGC 1800

TTCAGGGCCG AGTACAAGGC CAGCGGTGGC CCCTCCGTCT TCCAGAAGCC CGTCCGCTTC 1860

CAGGTGGACA TCAGCTCCTC TGAGGGGCCA GAGCCCTCCC CGCGACGGGA TGGCGGCGGT 1920

GGCGGAGGTG GCGTCTACTC TGTCACCTTT ACTCTCCTCT CCGGTCCCAG CCGTCGGTTC 1980

AAGCGAGTGG TGGAGACCAT CCAGGCACAG CTGCTGAGCA CTCACGACCA GCCCTCGGTG 2040

CAGGCCCTCA CAGACGAGAA GAACGGGGCG CAGACCCGGC CTGCCAGCAC CCCGCCCCGA 2100

AGCCTGCAGC CCCCGCCCGG CCGCCCAGAC CCGGAGCTGA CCAGCTCTCC CCGCCGAGGC 2160

CCCCCCAAGG ACAAGAAGCT CCTGGCCACC AACGGGACCC CTCTGCCCTG A 2211

Domain Profile

S: 13    gkVklakhketkekvavKiikkkklseeslekikrEieilkklkhpniikllevietkkk  72

         g Vkl +h  t++kva+Ki++++klse+ l k++rEi+ilk ++hp+++kl++v+e+kk+

Q: 1     GLVKLGVHCITGQKVAIKIVNREKLSESVLMKVEREIAILKLIEHPHVLKLHDVYENKKY  60

         679*********************************************************

S: 73    lylvleyasggeLfdyieekgrlkekearklfkqlvsavkYlhskgivHrDlKpeNllld  132

         lylvle++sggeLfdy+++kgrl+ keark+f+q+vsa++++hs +i+HrDlKpeNllld

Q: 61    LYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIVSALDFCHSYSICHRDLKPENLLLD  120

         ************************************************************

S: 133   kkenikiaDFGlanlfkegklletfcGsppYaaPellkgkkYegpkvDvWslGvvLyalv  192

         +k+ni+iaDFG+a+l   ++llet+cGsp+Ya+Pe++kg+kY+g+++D+Ws+Gv+L+al+

Q: 121   EKNNIRIADFGMASLQVGDSLLETSCGSPHYACPEVIKGEKYDGRRADMWSCGVILFALL  180

         ************************************************************

S: 193   tgklPfdeenlkellekilkgkleipkklskelesLlrklLvvdpekRatieeilkhewl  252

         +g+lPfd++nl++llek+++g +++p+ + ++++sLlr +++v+pekR+++e+i+kh+w+

Q: 181   VGALPFDDDNLRQLLEKVKRGVFHMPHFIPPDCQSLLRGMIEVEPEKRLSLEQIQKHPWY  240

         ***********************************************************5

Domain Sequence
(FASTA)

GLVKLGVHCI TGQKVAIKIV NREKLSESVL MKVEREIAIL KLIEHPHVLK LHDVYENKKY 60

LYLVLEHVSG GELFDYLVKK GRLTPKEARK FFRQIVSALD FCHSYSICHR DLKPENLLLD 120

EKNNIRIADF GMASLQVGDS LLETSCGSPH YACPEVIKGE KYDGRRADMW SCGVILFALL 180

VGALPFDDDN LRQLLEKVKR GVFHMPHFIP PDCQSLLRGM IEVEPEKRLS LEQIQKHPWY 240

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.
IPR015940	; UBA/transl_elong_EF1B_N_euk.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.
PS50030	; UBA; 1.

Prints

Created Date

20-Feb-2013