EKS-MYL-00345

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-MYL-00345

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/DCAMKL	439.5	4.1E-132	215	472	258

Status

Unreviewed

Ensembl Protein

ENSMLUP00000018082

UniProt Accession

G1P0D7;

Protein Name

Protein Synonyms/Alias

Gene Name

DCLK3

Gene Synonyms/Alias

DCLK3;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMLUG00000003533	ENSMLUP00000018082	ENSMLUT00000026667
ENSMLUG00000003533	ENSMLUP00000003213	ENSMLUT00000003530

Organism

Myotis lucifugus

Functional Description

Protein Length

472

Protein Sequence
(FASTA)

LKPRVVTVVK PGGHPLRKVT LLLNRRSVQT FEQLLADVSE ALGFPRWKSD RVRKLFNLKG 60

REIRSVSDFF REGDAFIAMG KEPLTLKNIQ AAMEELYPSK ARALTLSQQS RVPSPRAGRT 120

GGRVTATGAN PGTPLRREHP ADPKKPPRTR GEEQEAEKEK KPPVSGGRKM LPRDDQPARV 180

EKEPKMMAEE SKPERPGGRK RRPAGIISAN VEKQYETGRV IGDGNFAIVK ECQHRETRQA 240

YAMKIIDKAK LKGKEDMVDS EILIIQSLSH PNIVKLHEVY ETDTEIYLIM EYVQGGDLFD 300

AIIEHVKFPE RDAALMLMDL CKALVHMHDK NIVHRDLKPE NLLVQRNEDQ STTLKLADFG 360

LAKHVVRPVF TVCGTPTYVA PEILSEKGYG LEVDMWAAGV ILYILLCGFP PFRSLERDQD 420

ELFDIIQLGH FEFLAPYWDN ISEAAKDLVS RLLVVDPKKR YTAHQVLKHP WI 472

Nucleotide Sequence
(FASTA)

CTGAAGCCCA GGGTCGTGAC GGTGGTGAAG CCGGGTGGGC ACCCCCTGCG CAAGGTCACC 60

CTGCTCCTCA ATCGGCGCTC GGTGCAGACC TTCGAGCAGC TCCTGGCGGA CGTCTCGGAG 120

GCCTTGGGCT TCCCCCGGTG GAAGAGTGAT CGCGTGAGGA AACTGTTCAA CCTCAAGGGC 180

AGGGAGATCC GGAGCGTCTC TGATTTCTTC CGGGAAGGGG ATGCCTTCAT CGCCATGGGC 240

AAGGAACCCT TGACGTTGAA GAACATTCAG GCGGCCATGG AAGAGCTGTA CCCCAGCAAA 300

GCCCGGGCCC TGACGCTGAG CCAGCAGAGC AGGGTCCCTT CTCCGAGGGC GGGGAGGACG 360

GGTGGCAGGG TGACGGCCAC AGGAGCAAAC CCAGGAACCC CACTCAGGAG GGAGCACCCA 420

GCCGACCCCA AGAAGCCGCC CAGGACCCGA GGGGAGGAGC AGGAGGCAGA GAAGGAGAAA 480

AAGCCACCTG TGTCCGGCGG GAGAAAGATG CTTCCCAGAG ATGACCAACC CGCAAGGGTA 540

GAAAAGGAGC CCAAGATGAT GGCAGAGGAA AGCAAGCCAG AGAGGCCCGG TGGCCGGAAG 600

CGGCGGCCCG CGGGCATCAT CTCGGCCAAC GTGGAGAAGC AGTACGAGAC CGGCCGGGTC 660

ATCGGGGACG GCAACTTCGC CATCGTGAAG GAGTGCCAGC ACCGGGAGAC CAGGCAGGCC 720

TACGCCATGA AGATCATCGA CAAGGCCAAA CTCAAGGGCA AGGAGGACAT GGTCGACAGC 780

GAGATCTTAA TTATCCAGAG CCTCTCTCAC CCCAACATAG TGAAGCTGCA CGAAGTGTAC 840

GAAACGGACA CGGAGATCTA CCTGATCATG GAGTACGTGC AGGGCGGGGA CCTTTTCGAT 900

GCCATCATAG AACACGTGAA GTTCCCAGAG CGCGACGCCG CCCTCATGCT CATGGACTTG 960

TGTAAGGCTC TCGTGCACAT GCATGACAAG AACATCGTGC ACCGGGACCT CAAGCCGGAA 1020

AACCTCCTGG TTCAGAGGAA TGAGGACCAG TCGACGACCT TGAAGCTGGC TGACTTTGGC 1080

CTCGCGAAGC ACGTGGTGAG ACCAGTGTTC ACCGTGTGCG GGACCCCGAC TTACGTAGCA 1140

CCTGAAATTC TTTCTGAGAA AGGTTACGGG CTGGAGGTGG ACATGTGGGC CGCGGGCGTG 1200

ATCCTCTATA TCCTGCTGTG TGGCTTCCCC CCGTTCCGCA GCCTGGAGAG GGACCAGGAC 1260

GAGCTCTTCG ACATCATCCA GCTGGGCCAC TTCGAGTTCC TGGCCCCTTA CTGGGACAAC 1320

ATCTCTGAGG CTGCCAAAGA CCTGGTGAGC CGGTTGCTGG TGGTGGACCC CAAAAAGCGC 1380

TACACGGCCC ACCAAGTTCT TAAGCACCCC TGGATC 1416

Domain Profile

S: 1     yeigrviGdGnfavvkevreretgkeyalkiidksklkGkehlidneveilkkvkhpniv  60

         ye+grviGdGnfa+vke+++ret+++ya+kiidk+klkGke+++d+e+ i+++++hpniv

Q: 215   YETGRVIGDGNFAIVKECQHRETRQAYAMKIIDKAKLKGKEDMVDSEILIIQSLSHPNIV  274

         89**********************************************************

S: 61    klieeletetelylvlelvkgGdlfdaitkstkleerdaaimilelakalkylhelnivh  120

         kl+e++et+te+yl++e+v+gGdlfdai++ +k++erdaa m+++l+kal ++h++nivh

Q: 275   KLHEVYETDTEIYLIMEYVQGGDLFDAIIEHVKFPERDAALMLMDLCKALVHMHDKNIVH  334

         ************************************************************

S: 121   rdvkpenllvvekedgskslkladfGlaaevegplytvcGtPtyvaPeilaetGyglkvd  180

         rd+kpenllv+++ed+s++lkladfGla++v +p++tvcGtPtyvaPeil+e+Gygl+vd

Q: 335   RDLKPENLLVQRNEDQSTTLKLADFGLAKHVVRPVFTVCGTPTYVAPEILSEKGYGLEVD  394

         ************************************************************

S: 181   iWaaGvilyillvGfpPfrssdedqeelfdlilsgklefpsPyWdnisdkakdlvsrlle  240

         +WaaGvilyill+GfpPfrs ++dq+elfd+i+ g++ef +PyWdnis++akdlvsrll

Q: 395   MWAAGVILYILLCGFPPFRSLERDQDELFDIIQLGHFEFLAPYWDNISEAAKDLVSRLLV  454

         ************************************************************

S: 241   vdeekrltaeqilehpwv  258

         vd++kr+ta+q+l+hpw+

Q: 455   VDPKKRYTAHQVLKHPWI  472

         *****************8

Domain Sequence
(FASTA)

YETGRVIGDG NFAIVKECQH RETRQAYAMK IIDKAKLKGK EDMVDSEILI IQSLSHPNIV 60

KLHEVYETDT EIYLIMEYVQ GGDLFDAIIE HVKFPERDAA LMLMDLCKAL VHMHDKNIVH 120

RDLKPENLLV QRNEDQSTTL KLADFGLAKH VVRPVFTVCG TPTYVAPEIL SEKGYGLEVD 180

MWAAGVILYI LLCGFPPFRS LERDQDELFD IIQLGHFEFL APYWDNISEA AKDLVSRLLV 240

VDPKKRYTAH QVLKHPWI 258

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Dipodomys ordii"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Tupaia belangeri"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR020636	; Ca/CaM-dep_Ca-dep_prot_Kinase.
IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013