EKS-MYL-00261

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-MYL-00261

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
AGC/PDK1	419.7	5.4E-126	83	343	261

Status

Unreviewed

Ensembl Protein

ENSMLUP00000004165

UniProt Accession

G1P2R5;

Protein Name

Protein Synonyms/Alias

Gene Name

PDPK1

Gene Synonyms/Alias

PDPK1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMLUG00000004579	ENSMLUP00000004165	ENSMLUT00000004578

Organism

Myotis lucifugus

Functional Description

Protein Length

557

Protein Sequence
(FASTA)

ISFSWVHQYD TIPIQSSVVL CSCPSPSMVR TQTDSGSAPV PSGGSRQGPT MDSTAAESRP 60

SANSLQRAAQ PPPQPRKKRP EDFKFGKILG EGSFSTVVLA RELATSREYA IKILEKRHII 120

KENKVPYVTR EKDVMSCLDH PFFVKLYFTF QDDEKLYFGL SYAKNGELLK YIRKIGSFDE 180

TCTRFYTAEM VSALEYLHGR GIIHRDLKPE NILLNEDMHI QITDFGTAKV LSPESKQARA 240

NSFVGTAQYV SPELLTEKSA CKSSDLWALG CIIYQLVAGL PPFRAGNEYL IFQKIIKLEY 300

DFPEKFFPKA RDLVEKLLVL DATKRLGCEE MEGYGPLKAH SFFESITWEN LHHQTPPKLT 360

AYLPAMSEDD EDCYGNYDNL LSQFGCMQVS SSSSSHSLSA SDTGLPQRAG SNIEQYIHDL 420

DTNSFELDLQ FSEDEKRLLL EKQASGNPWH QFVENNLILK MGPVDKRKGL FARRRQLLLT 480

EGPHLYYVDP VNKVLKGEIP WSQELRPEAK NFKTFFVHTP NRTYYLMDPS GNAHKWCKKI 540

QEVWRHRYQS HPDTTVQ 557

Nucleotide Sequence
(FASTA)

ATCTCTTTTT CCTGGGTCCA CCAGTATGAC ACCATTCCTA TTCAGTCCAG CGTGGTGTTA 60

TGTTCCTGCC CATCCCCATC AATGGTGAGG ACCCAGACTG ATTCCGGCTC GGCCCCTGTT 120

CCAAGCGGTG GTAGCAGGCA GGGCCCCACC ATGGACAGCA CTGCGGCCGA GTCCCGACCA 180

AGTGCCAACT CACTGCAACG TGCCGCACAG CCACCACCAC AGCCTCGGAA GAAACGGCCA 240

GAAGACTTCA AATTCGGGAA AATTCTTGGT GAAGGATCTT TTTCAACAGT TGTCCTGGCC 300

CGAGAACTGG CAACCTCAAG GGAATATGCT ATTAAAATTC TAGAGAAACG TCACATTATC 360

AAAGAGAACA AGGTCCCGTA TGTAACCAGA GAGAAAGACG TGATGTCGTG CCTGGATCAC 420

CCCTTCTTTG TTAAACTTTA CTTCACGTTT CAGGATGATG AAAAGCTGTA TTTTGGCCTT 480

AGTTATGCCA AAAACGGAGA ACTACTTAAA TACATTCGCA AAATTGGTTC ATTCGATGAG 540

ACGTGCACCC GATTTTACAC AGCTGAGATG GTGTCTGCTC TAGAGTACTT GCATGGCAGG 600

GGCATCATTC ACAGGGACCT GAAACCAGAA AACATTTTGT TAAATGAAGA TATGCACATC 660

CAGATCACAG ATTTTGGAAC AGCAAAAGTA TTATCCCCAG AGAGTAAACA AGCCAGGGCC 720

AACTCGTTTG TAGGAACAGC CCAGTATGTT TCTCCAGAGC TGCTCACAGA GAAATCGGCC 780

TGTAAAAGTT CAGACCTTTG GGCTCTTGGA TGTATAATAT ACCAGCTTGT GGCAGGACTC 840

CCACCGTTCC GAGCCGGAAA CGAATATCTT ATATTTCAGA AGATCATTAA GTTGGAATAT 900

GATTTTCCTG AAAAATTCTT TCCTAAGGCA AGAGACCTTG TGGAAAAACT TTTGGTTTTA 960

GATGCCACAA AGCGATTAGG CTGTGAAGAA ATGGAAGGAT ATGGCCCTCT GAAAGCTCAT 1020

TCATTCTTTG AATCCATCAC ATGGGAGAAT CTGCATCATC AGACACCCCC GAAACTCACC 1080

GCTTACTTAC CAGCCATGTC GGAAGATGAT GAAGACTGCT ATGGAAACTA CGACAATCTC 1140

CTGAGCCAGT TTGGCTGCAT GCAAGTGTCA TCGTCATCAT CCTCCCACTC CCTGTCTGCC 1200

TCAGACACCG GTCTGCCACA GAGGGCGGGC AGCAACATCG AGCAGTATAT CCATGACCTG 1260

GACACTAATT CTTTTGAACT GGACTTACAG TTTTCCGAAG ATGAGAAGAG GTTATTATTG 1320

GAGAAGCAGG CCAGTGGAAA CCCTTGGCAC CAGTTTGTAG AAAATAATTT AATACTAAAA 1380

ATGGGTCCAG TAGATAAGCG AAAGGGTTTA TTTGCACGAC GGCGACAGTT ATTACTTACA 1440

GAAGGGCCAC ACTTATATTA TGTGGATCCT GTCAACAAAG TCCTGAAAGG TGAAATTCCA 1500

TGGTCACAAG AACTCCGACC AGAGGCCAAG AATTTTAAAA CCTTCTTTGT CCACACACCA 1560

AACAGGACGT ATTACCTGAT GGACCCGAGC GGGAATGCTC ACAAATGGTG CAAAAAGATT 1620

CAGGAGGTGT GGAGGCACAG ATACCAGAGT CACCCAGACA CCACCGTGCA GTGA 1674

Domain Profile

S: 1     fkfekelgeGsystvvlarekeskkeyaikvlekryiikekkvkyvtrekevlaklnehp  60

         fkf+k+lgeGs+stvvlare+++++eyaik+lekr+iike+kv+yvtrek+v++ l +hp

Q: 83    FKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTREKDVMSCL-DHP  141

         89******************************************************.9**

S: 61    givkLyatfqDeeslyfvleyakkGdllellkkvgsfdeactryyaaellsaleflhkkg  120

         ++vkLy+tfqD+e+lyf l+yak+G+ll++++k+gsfde+ctr+y+ae++sale+lh +g

Q: 142   FFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEMVSALEYLHGRG  201

         ************************************************************

S: 121   iihrDlkpeniLldkdgkilitDfGsakvlepklkedskkeeeesarsksfvGtaeyvsP  180

         iihrDlkpeniLl++d++i+itDfG+akvl+p++k+         ar++sfvGta+yvsP

Q: 202   IIHRDLKPENILLNEDMHIQITDFGTAKVLSPESKQ---------ARANSFVGTAQYVSP  252

         ******************************999999.........9**************

S: 181   elLtdsevskssDlWalgcilyqllaGkpPfraeneylifkkilkleyafpegfpekakd  240

         elLt+++++kssDlWalgci+yql+aG+pPfra neylif+ki+kley+fpe+f++ka+d

Q: 253   ELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPEKFFPKARD  312

         ************************************************************

S: 241   lveklLvkdakerltlee......ikahkff  265

         lveklLv da++rl++ee      +kah ff

Q: 313   LVEKLLVLDATKRLGCEEmegygpLKAHSFF  343

         ******************************9

Domain Sequence
(FASTA)

FKFGKILGEG SFSTVVLARE LATSREYAIK ILEKRHIIKE NKVPYVTREK DVMSCLDHPF 60

FVKLYFTFQD DEKLYFGLSY AKNGELLKYI RKIGSFDETC TRFYTAEMVS ALEYLHGRGI 120

IHRDLKPENI LLNEDMHIQI TDFGTAKVLS PESKQARANS FVGTAQYVSP ELLTEKSACK 180

SSDLWALGCI IYQLVAGLPP FRAGNEYLIF QKIIKLEYDF PEKFFPKARD LVEKLLVLDA 240

TKRLGCEEME GYGPLKAHSF F 261

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR011993	; PH_like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013