EKS-MYL-00210

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-MYL-00210

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDKL	519.8	1.3E-156	4	287	284

Status

Unreviewed

Ensembl Protein

ENSMLUP00000004317

UniProt Accession

G1P339;

Protein Name

Protein Synonyms/Alias

Gene Name

CDKL2

Gene Synonyms/Alias

CDKL2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMLUG00000004742	ENSMLUP00000004317	ENSMLUT00000004744

Organism

Myotis lucifugus

Functional Description

Protein Length

569

Protein Sequence
(FASTA)

MEKYENLGLV GEGSYGMVMK CRNKDTGRIV AIKKFLESDD DKMVKKIAMR EIKLLKQLRH 60

ENLVNLLEVC KKKKRWYLVF EFVDHTILDD LELFPNGLDY QLVQKYLFQI INGIGFCHSH 120

NIIHRDIKPE NILVSQSGVV KLCDFGFART LAAPGEVYTD YVATRWYRAP ELLVGDVKYG 180

KAVDIWAIGC LVTEMLMGEP LFPGDSDIDQ LYHIMTCLGN LIPRHQELFY KNPAFAGVRL 240

PEIKEMEPLE RRYPKLPEVV IDLAKKCLHI DPDKRPFCAE LLHHNFFCMD GFAERFSQEL 300

QLKIQKDARN ISLSKKSQNR KKEKEKDDVL GEERNTLVVQ DSNADPKIKD SRVLKIKGSK 360

IDGEKVEKTS RASNVSCLHD NGTSHIKTVP STSLRDCSNG SVDHTRNPGM AIPPLTHNLS 420

AVAPGINSGM GTIPGVQSYR VDEKTKKYCI PFVKPNQQTP SGIYNINMTK PITSEKSLLQ 480

ANKKRREYAK TDVHLPELNY NHLPELRALE GIARNSRLMR KENKNLSESQ IPSLAAIDLH 540

ASSVTLHQVP GSPLTEDSEA DLPWMEHQH 569

Nucleotide Sequence
(FASTA)

ATGGAAAAAT ATGAGAACCT AGGATTGGTT GGAGAAGGGA GCTATGGAAT GGTGATGAAG 60

TGTAGGAATA AAGATACTGG AAGAATTGTA GCCATTAAGA AGTTCTTAGA AAGTGATGAT 120

GACAAAATGG TTAAAAAAAT TGCTATGCGA GAAATCAAGT TGCTGAAGCA ACTGAGGCAT 180

GAAAATCTGG TGAATCTGTT GGAGGTGTGT AAGAAAAAAA AACGATGGTA CCTAGTCTTT 240

GAGTTTGTTG ACCATACCAT TCTTGATGAC TTGGAACTCT TTCCAAATGG ACTAGACTAC 300

CAGCTGGTTC AAAAGTATTT GTTTCAGATT ATTAATGGAA TTGGATTTTG TCATAGTCAC 360

AATATCATAC ACAGAGATAT CAAGCCAGAG AATATATTAG TCTCCCAGTC TGGAGTTGTC 420

AAGTTATGTG ATTTTGGATT TGCGCGGACA TTGGCAGCTC CTGGGGAGGT TTACACTGAT 480

TATGTGGCAA CCCGATGGTA CAGAGCTCCA GAACTATTGG TTGGTGATGT GAAGTATGGC 540

AAAGCTGTTG ACATATGGGC CATTGGTTGT CTGGTAACCG AAATGCTCAT GGGGGAGCCC 600

CTCTTTCCTG GAGATTCTGA TATTGATCAG CTATATCATA TTATGACGTG TTTAGGTAAC 660

CTCATTCCAA GGCACCAGGA GCTGTTTTAT AAAAACCCTG CGTTTGCGGG AGTAAGGTTG 720

CCTGAAATCA AGGAAATGGA ACCTCTTGAA AGACGCTATC CCAAGCTCCC TGAAGTTGTG 780

ATCGATTTAG CAAAGAAATG CTTACATATT GATCCAGACA AAAGGCCCTT CTGTGCTGAG 840

CTCCTGCACC ACAATTTCTT TTGTATGGAT GGATTTGCTG AACGGTTCTC TCAGGAACTA 900

CAGTTAAAAA TACAGAAAGA TGCCAGAAAT ATTTCTTTAT CTAAAAAATC CCAAAACAGA 960

AAGAAGGAGA AGGAAAAAGA TGACGTTTTA GGTGAGGAGA GAAACACACT TGTGGTACAG 1020

GATTCCAATG CTGATCCCAA AATTAAGGAT TCTAGAGTAT TAAAGATAAA AGGGTCAAAA 1080

ATTGATGGAG AAAAAGTTGA AAAAACCAGT CGAGCTTCAA ATGTCAGCTG TCTCCATGAC 1140

AACGGGACTA GCCACATCAA AACAGTGCCT TCAACAAGCC TCAGAGATTG CAGCAATGGC 1200

AGTGTGGACC ACACACGGAA TCCAGGCATG GCTATTCCTC CACTTACACA CAATCTTTCT 1260

GCAGTAGCTC CTGGTATTAA TTCTGGAATG GGGACTATCC CAGGAGTTCA GAGTTACAGA 1320

GTGGATGAGA AGACCAAGAA GTATTGTATT CCATTTGTTA AACCGAACCA ACAGACTCCA 1380

TCAGGCATTT ATAATATTAA CATGACCAAA CCAATCACTA GTGAAAAGAG CCTCCTTCAG 1440

GCAAATAAGA AAAGAAGAGA ATACGCAAAG ACAGATGTGC ATTTGCCTGA ATTAAACTAC 1500

AATCATCTCC CTGAACTGAG AGCCCTGGAA GGCATAGCTC GAAATTCCAG GCTAATGAGG 1560

AAAGAGAACA AAAACCTTTC AGAATCTCAA ATTCCTTCTC TGGCCGCTAT TGACTTGCAT 1620

GCCTCCAGTG TTACACTGCA TCAGGTACCA GGATCTCCCC TGACAGAGGA CTCGGAGGCT 1680

GACTTACCTT GGATGGAACA CCAGCACTGA 1710

Domain Profile

S: 1     yeklgkvGeGsyGvvlkcrnkdtgqivaikkfleseddkevkkialreikllkqlkhenl  60

         ye+lg vGeGsyG+v+kcrnkdtg+ivaikkfles+ddk+vkkia+reikllkql+henl

Q: 4     YENLGLVGEGSYGMVMKCRNKDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRHENL  63

         9***********************************************************

S: 61    vnllevfrrkkklylvfeyvdktvldelerypnGveeelvkkilyqilkaiefchknnii  120

         vnllev+++kk++ylvfe+vd+t+ld+le +pnG++++lv+k+l+qi+++i fch++nii

Q: 64    VNLLEVCKKKKRWYLVFEFVDHTILDDLELFPNGLDYQLVQKYLFQIINGIGFCHSHNII  123

         ************************************************************

S: 121   hrdikpenilisksgvvklcdfGfarllaapgdvytdyvatrwyrapellvgdtkyGksv  180

         hrdikpenil+s+sgvvklcdfGfar+laapg+vytdyvatrwyrapellvgd+kyGk+v

Q: 124   HRDIKPENILVSQSGVVKLCDFGFARTLAAPGEVYTDYVATRWYRAPELLVGDVKYGKAV  183

         ************************************************************

S: 181   dvwaiGcllaelltGeplfpgksdvdqlykirktlGeliprhqkifsknevfaGvklpev  240

         d+waiGcl++e+l+Geplfpg+sd+dqly+i+++lG+liprhq++f+kn+ faGv+lpe+

Q: 184   DIWAIGCLVTEMLMGEPLFPGDSDIDQLYHIMTCLGNLIPRHQELFYKNPAFAGVRLPEI  243

         ************************************************************

S: 241   edleslekkypklnevlldllkkclkldpaerlsceellkheyf  284

         +++e+le++ypkl ev++dl+kkcl++dp++r +c+ell+h++f

Q: 244   KEMEPLERRYPKLPEVVIDLAKKCLHIDPDKRPFCAELLHHNFF  287

         ******************************************98

Domain Sequence
(FASTA)

YENLGLVGEG SYGMVMKCRN KDTGRIVAIK KFLESDDDKM VKKIAMREIK LLKQLRHENL 60

VNLLEVCKKK KRWYLVFEFV DHTILDDLEL FPNGLDYQLV QKYLFQIING IGFCHSHNII 120

HRDIKPENIL VSQSGVVKLC DFGFARTLAA PGEVYTDYVA TRWYRAPELL VGDVKYGKAV 180

DIWAIGCLVT EMLMGEPLFP GDSDIDQLYH IMTCLGNLIP RHQELFYKNP AFAGVRLPEI 240

KEMEPLERRY PKLPEVVIDL AKKCLHIDPD KRPFCAELLH HNFF 284

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013