EKS-MYL-00227

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-MYL-00227

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
STE/STE7	387.9	2.3E-116	53	314	262

Status

Unreviewed

Ensembl Protein

ENSMLUP00000006110

UniProt Accession

G1P7K5;

Protein Name

Protein Synonyms/Alias

Gene Name

MAP2K6

Gene Synonyms/Alias

MAP2K6;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMLUG00000006692	ENSMLUP00000006110	ENSMLUT00000006692

Organism

Myotis lucifugus

Functional Description

Protein Length

334

Protein Sequence
(FASTA)

MSQSKGKKRN PGLKIPKEAF EQPQTSSTPP RDLDSKACIS IGNQNFEVKA DDLEPIMELG 60

RGAYGVVEKM RHVPSGQIMA VKRIRATVNS QEQKRLLMDL DVSMRTVDCP FTVTFYGALF 120

REGDVWICME LMDTSLDKFY KQVIDKGQTI PEDILGKIAV SIVKALEHLH SKLSVIHRDV 180

KPSNVLINAL GQVKMCDFGI SGYLVDSVAK TIDAGCKPYM APERINPELN QKGYSVKSDI 240

WSLGITMIEL AILRFPYDSW GTPFQQLKQV VEEPSPQLPA DKFSEEFVDF TSQCLKKNSK 300

ERPTYPELMQ HPFFTLHESK ATDVASFVKL IIGD 334

Nucleotide Sequence
(FASTA)

ATGTCTCAGT CGAAAGGCAA GAAGCGAAAT CCTGGCCTCA AAATTCCCAA AGAAGCATTT 60

GAACAGCCCC AGACCAGTTC CACGCCGCCT CGAGATTTAG ACTCCAAAGC TTGCATTTCT 120

ATCGGAAACC AGAACTTTGA GGTGAAGGCA GATGACCTGG AGCCTATCAT GGAGCTGGGC 180

CGAGGTGCGT ACGGAGTGGT GGAGAAGATG AGACATGTGC CCAGCGGGCA GATCATGGCA 240

GTGAAGCGGA TCCGGGCCAC TGTGAACAGC CAGGAGCAGA AAAGGCTACT GATGGACCTG 300

GATGTCTCCA TGAGGACGGT GGACTGTCCC TTTACGGTCA CCTTTTACGG CGCGCTCTTC 360

CGGGAGGGTG ATGTTTGGAT CTGCATGGAG CTCATGGATA CGTCGCTAGA TAAATTCTAC 420

AAACAAGTGA TTGATAAAGG CCAAACCATT CCAGAGGACA TCTTAGGGAA AATAGCAGTT 480

TCTATTGTAA AAGCATTAGA GCATTTGCAC AGTAAGCTCT CTGTCATCCA TCGAGACGTC 540

AAGCCTTCCA ACGTGCTCAT CAATGCTCTG GGCCAAGTGA AGATGTGCGA CTTTGGCATC 600

AGTGGCTACC TTGTGGACTC GGTGGCTAAA ACTATCGATG CAGGATGCAA ACCGTACATG 660

GCTCCGGAAA GGATAAACCC GGAGCTCAAC CAGAAGGGCT ACAGTGTGAA GTCTGACATT 720

TGGAGTCTGG GCATCACCAT GATTGAGTTG GCCATCCTTC GGTTTCCCTA CGATTCATGG 780

GGAACTCCTT TCCAGCAGCT CAAACAGGTG GTGGAGGAGC CGTCACCACA GCTGCCCGCA 840

GACAAGTTCT CCGAAGAGTT TGTCGACTTT ACCTCGCAGT GCTTGAAGAA GAATTCCAAA 900

GAACGGCCAA CGTATCCAGA GCTTATGCAA CATCCGTTTT TCACTCTACA TGAATCCAAA 960

GCAACAGACG TGGCATCTTT TGTAAAATTG ATTATTGGAG ACTAA 1005

Domain Profile

S: 1     lekleelGaGnggvVekvlhkksgkilavKtirleikkeeqkqilrelevlkkssnspyi  60

         le + elG+G++gvVek++h +sg+i+avK+ir++++++eqk++l++l+v +++ ++p++

Q: 53    LEPIMELGRGAYGVVEKMRHVPSGQIMAVKRIRATVNSQEQKRLLMDLDVSMRTVDCPFT  112

         57789*******************************************************

S: 61    vkfyGafvsegdvsicmelmdgtsldkvlkkvlekkkripekvlgkiavavvkaleylke  120

         v+fyGa+++egdv+icmelmd tsldk++k+v++k ++ipe++lgkiav++vkale+l++

Q: 113   VTFYGALFREGDVWICMELMD-TSLDKFYKQVIDKGQTIPEDILGKIAVSIVKALEHLHS  171

         *********************.**************************************

S: 121   klkiiHRDvKPsNiLvnskGevKlCDFGvsgqlvdsiAksa.vGtksYmaPErieg...k  176

         kl++iHRDvKPsN+L+n+ G+vK+CDFG+sg+lvds+Ak++ +G+k+YmaPEri++   +

Q: 172   KLSVIHRDVKPSNVLINALGQVKMCDFGISGYLVDSVAKTIdAGCKPYMAPERINPelnQ  231

         ********************************************************9999

S: 177   kkYsvksdvWslGltlvelatgrypyeklkeilellkaivneeppklpeeefseefqefv  236

         k Ysvksd+WslG+t++ela+ r+py+++ +++++lk++v+e++p+lp+++fseef++f

Q: 232   KGYSVKSDIWSLGITMIELAILRFPYDSWGTPFQQLKQVVEEPSPQLPADKFSEEFVDFT  291

         9***********************************************************

S: 237   skClkkdekeRpklkellkhafi  259

         s+Clkk++keRp++ el++h+f+

Q: 292   SQCLKKNSKERPTYPELMQHPFF  314

         *********************96

Domain Sequence
(FASTA)

LEPIMELGRG AYGVVEKMRH VPSGQIMAVK RIRATVNSQE QKRLLMDLDV SMRTVDCPFT 60

VTFYGALFRE GDVWICMELM DTSLDKFYKQ VIDKGQTIPE DILGKIAVSI VKALEHLHSK 120

LSVIHRDVKP SNVLINALGQ VKMCDFGISG YLVDSVAKTI DAGCKPYMAP ERINPELNQK 180

GYSVKSDIWS LGITMIELAI LRFPYDSWGT PFQQLKQVVE EPSPQLPADK FSEEFVDFTS 240

QCLKKNSKER PTYPELMQHP FF 262

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013