EKS-MYL-00160

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-MYL-00160

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
AGC/NDR	515.6	3.7E-155	89	382	294

Status

Unreviewed

Ensembl Protein

ENSMLUP00000006524

UniProt Accession

G1P8L5;

Protein Name

Protein Synonyms/Alias

Gene Name

STK38

Gene Synonyms/Alias

STK38;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMLUG00000007149	ENSMLUP00000006524	ENSMLUT00000007151

Organism

Myotis lucifugus

Functional Description

Protein Length

466

Protein Sequence
(FASTA)

MAMTGSTPCS SMSNHTKERV TMTKVTLENF YSNLIAQHEE REMRQKKLEK VMEEEGLKDE 60

EKRLRRSAHA RKETEFLRLK RTRLGLEDFE SLKVIGRGAF GEVRLVQKKD TGHVYAMKIL 120

RKADMLEKEQ VGHIRAERDI LVEADSLWVV KMFYSFQDKL NLYLIMEFLP GGDMMTLLMK 180

KDTLTEEETQ FYIAETVLAI DSIHQLGFIH RDIKPDNLLL DSKGHVKLSD FGLCTGLKKA 240

HRTEFYRNLN HSLPSDFTFQ NMNSKRKAET WKRNRRQLAF STVGTPDYIA PEVFMQTGYN 300

KLCDWWSLGV IMYEMLIGYP PFCSETPQET YKKVMNWKET LTFPPEVPIS EKAKALILRF 360

CCEWEHRIGA PGVEEIKSNS FFEGVDWEHI RPRPLALVVA AQQSIDDTSN FDEFPESDIL 420

KPTVATSNHP ETDYKNKDWV FINYTYKRFE GLTARGAIPS YMKAAK 466

Nucleotide Sequence
(FASTA)

ATGGCAATGA CCGGCTCCAC ACCTTGCTCG TCCATGAGTA ATCACACAAA AGAAAGGGTG 60

ACAATGACCA AAGTGACGCT GGAGAATTTT TATAGCAATC TTATCGCTCA ACATGAAGAA 120

CGAGAAATGA GACAAAAGAA GTTAGAAAAA GTGATGGAAG AAGAAGGCCT AAAGGATGAA 180

GAGAAACGAC TCAGGCGATC AGCTCATGCT CGGAAGGAAA CAGAGTTTCT TCGTTTGAAG 240

AGGACAAGAC TTGGATTGGA AGATTTTGAG TCCTTAAAAG TAATAGGCAG AGGAGCATTT 300

GGTGAGGTTC GGCTTGTTCA GAAGAAAGAT ACAGGGCATG TGTATGCAAT GAAAATACTC 360

CGTAAAGCAG ATATGCTTGA AAAAGAGCAG GTTGGCCACA TTCGTGCGGA GCGTGACATT 420

CTAGTGGAGG CAGACAGTTT GTGGGTTGTG AAAATGTTCT ATAGTTTTCA GGATAAGCTA 480

AACCTCTACC TAATCATGGA GTTCCTGCCT GGAGGGGACA TGATGACCCT CCTGATGAAA 540

AAAGATACTT TGACAGAGGA GGAGACTCAG TTTTATATAG CAGAGACAGT GTTAGCCATA 600

GACTCCATTC ACCAGCTTGG ATTCATCCAC AGAGACATCA AACCAGACAA CCTTCTCCTG 660

GACAGCAAGG GCCATGTGAA ACTTTCTGAT TTTGGCCTTT GCACAGGCCT GAAGAAAGCA 720

CACAGGACAG AATTTTATAG GAATTTGAAC CACAGCCTTC CCAGTGATTT CACTTTCCAG 780

AACATGAATT CCAAAAGGAA AGCAGAAACC TGGAAAAGAA ATAGACGTCA GCTAGCCTTC 840

TCCACAGTAG GGACGCCTGA CTACATTGCT CCCGAGGTGT TCATGCAGAC CGGGTACAAC 900

AAGCTCTGTG ATTGGTGGTC GCTTGGCGTG ATCATGTATG AGATGCTCAT TGGCTACCCA 960

CCTTTCTGTT CTGAGACCCC TCAAGAGACA TATAAGAAGG TGATGAACTG GAAAGAAACG 1020

CTGACTTTCC CTCCAGAAGT TCCCATCTCT GAGAAAGCCA AGGCCCTGAT TCTGAGATTC 1080

TGCTGTGAAT GGGAACATAG GATTGGAGCC CCTGGAGTTG AGGAAATCAA AAGTAATTCT 1140

TTTTTTGAAG GTGTTGACTG GGAACATATC AGGCCCAGGC CACTCGCATT AGTGGTTGCT 1200

GCACAGCAGA GCATTGACGA TACCTCAAAC TTCGATGAGT TTCCAGAATC TGATATTCTT 1260

AAGCCAACAG TGGCAACAAG TAATCACCCT GAGACTGACT ACAAGAACAA GGACTGGGTC 1320

TTCATCAATT ACACATACAA GCGCTTTGAG GGCCTGACTG CGCGGGGGGC AATACCTTCC 1380

TACATGAAAG CGGCAAAATA G 1401

Domain Profile

S: 1     feklkvigkGafGevrlvrkkdtkevyalkilrkkdllkknqvahvkaerdilaeadsew  60

         fe+lkvig+GafGevrlv+kkdt++vya+kilrk+d+l+k+qv h++aerdil+eads w

Q: 89    FESLKVIGRGAFGEVRLVQKKDTGHVYAMKILRKADMLEKEQVGHIRAERDILVEADSLW  148

         899*********************************************************

S: 61    vvklyysfqdkenlylvmeylPGGdlmtllikkeilkeelarfyiaelvlavesvhklGf  120

         vvk++ysfqdk nlyl+me+lPGGd+mtll+kk++l+ee+++fyiae+vla++s+h+lGf

Q: 149   VVKMFYSFQDKLNLYLIMEFLPGGDMMTLLMKKDTLTEEETQFYIAETVLAIDSIHQLGF  208

         ************************************************************

S: 121   ihrdlkPdnllidakGhikltdfGlctGlkkthrseyykelekakeddleaseelkvler  180

         ihrd+kPdnll+d+kGh+kl+dfGlctGlkk+hr+e+y++l+++ ++d+ ++    ++++

Q: 209   IHRDIKPDNLLLDSKGHVKLSDFGLCTGLKKAHRTEFYRNLNHSLPSDFTFQ----NMNS  264

         *************************************************555....5555

S: 181   rkk....kknrrllayslvGtpdyiapevlekkgynklcdwWslGvilyemlvGypPfla  236

         ++k    k+nrr+la+s+vGtpdyiapev++++gynklcdwWslGvi+yeml+GypPf++

Q: 265   KRKaetwKRNRRQLAFSTVGTPDYIAPEVFMQTGYNKLCDWWSLGVIMYEMLIGYPPFCS  324

         5544556*****************************************************

S: 237   etpqetykkvinwketlkfpeevelseeakdlierliadaekrlgkkGvdeikkhpff  294

         etpqetykkv+nwketl+fp+ev++se+ak li r+++++e+r+g+ Gv+eik+++ff

Q: 325   ETPQETYKKVMNWKETLTFPPEVPISEKAKALILRFCCEWEHRIGAPGVEEIKSNSFF  382

         *********************************************************9

Domain Sequence
(FASTA)

FESLKVIGRG AFGEVRLVQK KDTGHVYAMK ILRKADMLEK EQVGHIRAER DILVEADSLW 60

VVKMFYSFQD KLNLYLIMEF LPGGDMMTLL MKKDTLTEEE TQFYIAETVL AIDSIHQLGF 120

IHRDIKPDNL LLDSKGHVKL SDFGLCTGLK KAHRTEFYRN LNHSLPSDFT FQNMNSKRKA 180

ETWKRNRRQL AFSTVGTPDY IAPEVFMQTG YNKLCDWWSL GVIMYEMLIG YPPFCSETPQ 240

ETYKKVMNWK ETLTFPPEVP ISEKAKALIL RFCCEWEHRI GAPGVEEIKS NSFF 294

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR000961	; AGC-kinase_C.
IPR011009	; Kinase-like_dom.
IPR017892	; Pkinase_C.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069	; Pkinase; 1.
PF00433	; Pkinase_C; 1.

SMARTs

SM00133	; S_TK_X; 1.
SM00220	; S_TKc; 1.

Prosites

PS51285	; AGC_KINASE_CTER; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013