EKS-MYL-00459

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-MYL-00459

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/MAPK	403.5	4.6E-121	55	347	293

Status

Unreviewed

Ensembl Protein

ENSMLUP00000007347

UniProt Accession

G1PAM5;

Protein Name

Protein Synonyms/Alias

Gene Name

MAPK7

Gene Synonyms/Alias

MAPK7;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMLUG00000008040	ENSMLUP00000007347	ENSMLUT00000008041

Organism

Myotis lucifugus

Functional Description

Protein Length

810

Protein Sequence
(FASTA)

MAEPLKEEDG EDGSGEPPGL GKAEPASTAA SVAAKNLALL KARSLDVTFD VGDEYEIIET 60

IGNGAYGVVS SARRRLTGQQ VAIKKIPNAF DVVTNAKRTL RELKILKHFK HDNIIAIKDI 120

LRPTVPYGEF TSVYVVLDLM ESDLHQIIHS SQPLTLEHVR YFLYQLLRGL KYMHSAQVIH 180

RDLKPSNLLV NENCELKIGD FGMARGLCTS PAEHQYFMTE YVATRWYRAP ELMLSLHEYT 240

QAIDLWSVGC IFGEMLARRQ LFPGKNYVHQ LQLIMMVLGT PSPAVIQAVG AERVRAYIQS 300

LPPRQPVPWE TVYPGADRQA LSLLGRMLRF EPSARMSAAA ALRHPFLAKY HDPDDEPDCA 360

PPFDFAFDRE ALTRERIKEA IVAEIEDFHA RREGIRQQIR FQPSLQPVAS EPSCPDIEML 420

SSWAPSGDCA MESPPPAPLP CPGPAPDTID MTLQPPPALA SEPAPPKREG AISDNTKAAL 480

KAALLKSLRS RLRDGPSAPL EAPEPRKPVT AQERQREREE KRRRRQERAK EREKRRQERE 540

RKERGTGASG GPSTDPLAGL VLSDNDRSLL ERWTRMAQPP APTPAPAPAT VTTPPARPTS 600

PAGSVAQPTG PPPPAGATPG PAPQPACPAA GPAPHPAGPP RPVPGPAPLQ TTTTSSLLAP 660

QSLVPPPGMP GSSTLGVLPY FPPGPAPPNP RGTPQPSTSE SPDVNLVTQQ LSKSQVEDPL 720

PPAFSGTPKG SGAGYGVGFN LEEFLSQSFD MGVADGPQDG QTDSASLSAS LLADWLEGHG 780

MNPSDIESLQ REIQMDSPML LADLPDLQEP 810

Nucleotide Sequence
(FASTA)

ATGGCCGAGC CCCTGAAGGA GGAAGACGGC GAGGACGGCT CTGGGGAGCC CCCCGGGCTA 60

GGGAAGGCGG AGCCCGCCAG CACCGCTGCC TCCGTAGCGG CCAAGAACCT GGCCCTGCTG 120

AAAGCTCGCT CCTTGGACGT GACCTTTGAC GTGGGGGACG AGTACGAGAT CATCGAGACC 180

ATCGGCAACG GCGCCTACGG GGTGGTGTCC TCCGCCCGCC GCCGCCTGAC CGGCCAGCAG 240

GTGGCCATTA AGAAGATCCC TAATGCGTTT GATGTGGTGA CTAATGCCAA GCGGACCCTC 300

AGGGAGCTGA AGATCCTCAA GCACTTCAAG CATGACAACA TCATCGCCAT CAAGGACATC 360

CTGAGGCCCA CCGTGCCCTA CGGCGAGTTT ACGTCTGTTT ACGTGGTCCT GGACCTGATG 420

GAGAGCGACC TGCACCAGAT CATCCACTCT TCGCAGCCGC TCACCCTGGA GCACGTGCGC 480

TACTTCCTGT ACCAGCTGCT ACGGGGCCTC AAGTACATGC ACTCGGCTCA GGTCATCCAC 540

CGTGACCTCA AGCCCTCTAA CTTGTTGGTG AATGAGAACT GTGAGCTCAA GATCGGTGAC 600

TTCGGCATGG CGCGGGGCCT GTGCACCTCG CCTGCTGAGC ATCAGTACTT CATGACCGAA 660

TATGTGGCCA CGCGCTGGTA CCGTGCCCCT GAGCTCATGC TGTCGCTGCA TGAGTACACG 720

CAGGCTATTG ACCTGTGGTC CGTGGGCTGC ATCTTTGGTG AGATGCTGGC CAGGCGCCAG 780

CTCTTCCCAG GCAAAAACTA TGTACACCAG CTGCAGCTGA TCATGATGGT GTTGGGTACC 840

CCATCGCCAG CTGTGATTCA GGCTGTAGGG GCTGAAAGGG TACGGGCATA TATTCAGAGT 900

CTGCCACCAC GCCAGCCTGT GCCCTGGGAG ACAGTGTACC CAGGTGCTGA CCGCCAGGCC 960

CTCTCACTGC TGGGGCGAAT GCTGCGTTTT GAGCCCAGTG CCCGCATGTC AGCAGCTGCT 1020

GCCCTTCGCC ACCCCTTCCT GGCCAAGTAC CATGACCCTG ATGATGAGCC TGACTGTGCC 1080

CCACCCTTTG ACTTTGCCTT TGACCGGGAA GCCCTCACCC GGGAGCGGAT TAAGGAGGCC 1140

ATTGTGGCCG AGATTGAGGA CTTTCATGCC AGGCGCGAGG GCATCCGCCA GCAGATACGC 1200

TTCCAGCCTT CTCTGCAGCC TGTGGCCAGT GAGCCTAGCT GCCCCGACAT TGAGATGCTC 1260

AGTTCCTGGG CTCCCAGTGG GGACTGTGCC ATGGAGTCAC CTCCGCCAGC TCCACTGCCG 1320

TGCCCTGGCC CTGCACCGGA CACCATTGAT ATGACCCTGC AGCCACCCCC CGCGTTGGCC 1380

AGTGAACCAG CCCCTCCAAA GAGGGAGGGT GCCATCTCCG ACAACACCAA GGCAGCCCTC 1440

AAAGCTGCCC TGCTCAAGTC CTTGCGGAGC CGGCTCCGAG ATGGGCCCAG TGCCCCCCTA 1500

GAAGCACCGG AGCCTCGGAA GCCAGTGACA GCCCAGGAGC GCCAGCGTGA GCGGGAAGAG 1560

AAGCGGCGGC GGAGGCAGGA GCGAGCAAAG GAGCGGGAAA AGCGGCGGCA GGAGCGGGAG 1620

CGCAAGGAGC GAGGGACCGG GGCCTCTGGG GGCCCCTCCA CCGATCCCCT GGCTGGGCTG 1680

GTGCTTAGTG ACAATGATCG CAGCCTGCTG GAGCGCTGGA CTCGGATGGC CCAGCCCCCA 1740

GCCCCCACCC CTGCACCAGC CCCTGCCACA GTAACAACAC CTCCGGCCCG GCCCACCAGT 1800

CCTGCTGGCT CTGTAGCCCA GCCCACTGGA CCCCCACCAC CTGCAGGCGC CACCCCTGGT 1860

CCTGCACCAC AGCCGGCCTG CCCAGCCGCT GGCCCTGCTC CCCACCCTGC TGGCCCTCCT 1920

AGGCCTGTGC CTGGCCCTGC TCCACTCCAG ACCACCACCA CCTCCAGCCT CCTGGCCCCC 1980

CAGTCGCTTG TGCCACCCCC TGGGATGCCT GGTTCCAGCA CCCTGGGTGT TCTGCCTTAC 2040

TTCCCACCTG GCCCAGCCCC TCCAAACCCC AGGGGGACCC CTCAACCCTC CACCTCAGAG 2100

TCACCCGATG TCAACCTGGT GACCCAGCAG CTGTCCAAGT CTCAGGTGGA GGACCCTCTG 2160

CCCCCCGCAT TCTCGGGCAC GCCAAAGGGC AGTGGGGCCG GTTATGGCGT TGGCTTTAAC 2220

CTGGAAGAAT TCCTCAGCCA GTCTTTCGAT ATGGGCGTGG CGGATGGGCC ACAGGATGGC 2280

CAGACAGACT CGGCCTCGCT CTCAGCATCC CTGCTGGCTG ACTGGCTCGA GGGCCACGGC 2340

ATGAACCCTT CTGACATCGA GTCTCTGCAG CGTGAGATCC AGATGGATTC CCCGATGCTG 2400

CTGGCTGACC TGCCTGACCT CCAGGAGCCC TGA 2433

Domain Profile

S: 1     yeslkplgeGaygvvvsavdkrteervaikklsrpfqketsakrtlRElkllkelkheNi  60

         ye ++++g+Gaygvv sa ++ t+++vaikk+ ++f+  t+akrtlRElk+lk++kh+Ni

Q: 55    YEIIETIGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKILKHFKHDNI  114

         77899*******************************************************

S: 61    iklldvftpeeeleelkdvYlvtelmetdLkkviksq.klsdehiklllyqilrglkylH  119

         i + d+++p+  + e+++vY+v +lme+dL+++i+s+  l+ eh++++lyq+lrglky+H

Q: 115   IAIKDILRPTVPYGEFTSVYVVLDLMESDLHQIIHSSqPLTLEHVRYFLYQLLRGLKYMH  174

         ***********************************9889*********************

S: 120   sanviHrDlKPsNllvnedcelkildFGlarsadkekekk...lteyvatrwYraPeill  176

         sa+viHrDlKPsNllvne+celki dFG+ar   ++  ++   +teyvatrwYraPe++l

Q: 175   SAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHqyfMTEYVATRWYRAPELML  234

         *******************************955444333489*****************

S: 177   slkeytkavDiWsvGCIlaElltgkplfpgkdeidqlekilevlgtpseeflkkieseea  236

         sl+eyt+a+D+WsvGCI++E+l++++lfpgk++++ql++i+ vlgtps  +++++  e++

Q: 235   SLHEYTQAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERV  294

         ************************************************************

S: 237   rnyikslpkkkkkdfeelfpkaseealdLleklLvldpdkRisveeaLehpYl  289

         r+yi+slp+++  ++e+++p a+++al Ll ++L ++p+ R+s++ aL+hp+l

Q: 295   RAYIQSLPPRQPVPWETVYPGADRQALSLLGRMLRFEPSARMSAAAALRHPFL  347

         ***************************************************97

Domain Sequence
(FASTA)

YEIIETIGNG AYGVVSSARR RLTGQQVAIK KIPNAFDVVT NAKRTLRELK ILKHFKHDNI 60

IAIKDILRPT VPYGEFTSVY VVLDLMESDL HQIIHSSQPL TLEHVRYFLY QLLRGLKYMH 120

SAQVIHRDLK PSNLLVNENC ELKIGDFGMA RGLCTSPAEH QYFMTEYVAT RWYRAPELML 180

SLHEYTQAID LWSVGCIFGE MLARRQLFPG KNYVHQLQLI MMVLGTPSPA VIQAVGAERV 240

RAYIQSLPPR QPVPWETVYP GADRQALSLL GRMLRFEPSA RMSAAAALRH PFL 293

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Anolis carolinensis"; ?>Bos taurus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pelodiscus sinensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Takifugu rubripes"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004707	; F:MAP kinase activity
GO:0000165	; P:MAPK cascade

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR003527	; MAP_kinase_CS.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS01351	; MAPK; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013