EPS-MYL-00031

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-MYL-00031

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPM/PP2C	190.3	5.1E-56	789	1035	247

Status

Unreviewed

Ensembl Protein

ENSMLUP00000007942

UniProt Accession

G1PC20;

Protein Name

Protein Synonyms/Alias

Gene Name

PHLPP2

Gene Synonyms/Alias

PHLPP2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMLUG00000008702	ENSMLUP00000007942	ENSMLUT00000008716

Organism

Myotis lucifugus

Functional Description

Protein Length

1325

Protein Sequence
(FASTA)

MKRNGSRNCL NRRSRFGSRE RDWLREDVKR GCVYLYGADT TTATTTATSS ASSSSASSSS 60

SDLHLVLCTV ETPASEICAG EGRESLYLQL HGDLVRRLEP TERPLQIVYD YLSRLGYDDP 120

VRIQEEAANP DLGCMLRFYG EKPCQMDQLD RILLSGIYNV RKGKTQLHKW AERLVVLCGT 180

CLIVSSVKDC QTGKMHILPL VGGKVEEVKR RQYSLAFSSA GAQAQTYHVS FETLAEYQRW 240

QRQASKVVSQ RISTVDLSCY SLEEVPEHLF YSQDITYLNL RHNFMQLERP GGLDTLYKFS 300

HLKGLNLSHN KLGLFPVLLC EISTLTELNL SCNGFHDLPS QIGNLLNLQT LCLDGNFLTT 360

LPEELGNLQQ LSSLGISFNN FSHIPEVYER LTMLDKVVMA GNQLEVLNLG VLSRMSHIKH 420

VDLRILRMNH LKTVVIENLE GNKYITHMDL RDNQLTDLDL SSFCSLEQLH CERNQLRELT 480

LSGFSLRTLY ANSNRLTAVN VYPVPSLLTS LELSRNQLEC VPDWACEAKK IEVLDVSYNL 540

LTEGPMRILS SLSLRKLMVG HNHVQTLPVL VEHIPLEVLD IQHNLLTRLP DTLFSKALNL 600

RYLNASANSL ESLPSASAGE ESLSALQLLY LTNNLLTDQC VPVLVGHPHL RILHLANNQL 660

QTFPASKLNK LEQLEELNLS GNKLKTIPTT IANCKRLHTL VAHSNNISIF PEILQLPQIQ 720

FVDLSCNDLT EILIPEALPA TLQDLDLTGN TNLVLEHKTL DTFSHITTLK IDQKPLPTTD 780

PTVTSTFWSH GLAEMAGQRN KLCVSSLAVD TFAEGVGAVY GMFDGDRNEE LPRLLQCTMA 840

DVLLEEVQQS SSDTVSMAHT FLVSHRKLGM AGQKLGSSAL LCYIRPDTAD STSSFSLTVA 900

NVGTCQAVLC RGGKPVPLSK VFSLEQDADE AQRVKDQKAI ITEDNKVNGV TCCTRMLGCT 960

YLYPWILPKP YISSTTLTIQ DELLILGNKA LWEHLSYTEA VSAVRHVQDP LAAAKKLCTL 1020

AQSYGCQDNV GAIVVYLNIG EEGCTCEMNG LSLPGPVGFA PTTTIKDPLK PTTPSSSSGI 1080

ASEFSSEMST SEVSSEVGST ASDEHNTAGL DASLLPRPER RCSLHPTPTS VVFQRQPSCA 1140

TFSSNQSDNG LDSDDDQPVE GVITNGSKVE VEVDIHCCRG RENSPTLPKN SPAPRPEEHG 1200

RGLFFGIRRQ NSVNSGILLP MSKDKMELQK SPSTSCLYGK KLSNGSIVPL EDSLNLIEVA 1260

TEAPKKKTGY FAAPTQLEPE DQFVVPRDLE EEVKEQMKQH QESRPEPELI EEDRTELPEE 1320

FDTAL 1325

Nucleotide Sequence
(FASTA)

ATGAAACGCA ATGGGAGCAG AAATTGTTTG AATAGGAGAA GTAGGTTTGG TTCTCGAGAA 60

AGAGACTGGC TGAGAGAAGA TGTGAAGAGA GGCTGTGTTT ACCTTTATGG AGCAGACACG 120

ACCACTGCCA CTACAACCGC CACCTCCTCT GCCTCCTCCT CCTCCGCCTC CTCCTCATCC 180

TCCGACTTAC ATCTTGTCCT TTGCACAGTA GAGACTCCAG CATCAGAAAT ATGTGCTGGA 240

GAGGGAAGGG AAAGTCTTTA TTTACAGTTG CATGGAGACC TGGTCAGGAG ATTGGAACCC 300

ACCGAACGAC CTCTTCAGAT AGTTTATGAT TACTTATCCA GGCTGGGCTA TGATGACCCT 360

GTGCGCATAC AGGAGGAGGC AGCAAATCCC GACCTCGGCT GCATGCTTCG CTTTTATGGT 420

GAGAAACCAT GCCAGATGGA TCAACTGGAT CGAATCCTTC TCTCTGGCAT CTATAATGTA 480

CGCAAGGGGA AGACCCAGCT GCATAAGTGG GCTGAACGCC TAGTTGTTCT CTGTGGCACC 540

TGCCTCATCG TTTCCTCAGT GAAGGATTGT CAAACTGGAA AGATGCACAT TTTGCCTCTG 600

GTTGGGGGAA AGGTAGAAGA AGTGAAGCGA AGGCAGTACT CCCTTGCATT CAGCTCAGCT 660

GGAGCCCAGG CTCAGACCTA TCATGTCAGC TTTGAGACTT TGGCTGAGTA CCAGAGATGG 720

CAACGGCAAG CATCCAAGGT GGTGTCCCAG CGAATCAGTA CTGTCGACCT CTCATGTTAC 780

AGCCTCGAGG AGGTTCCTGA GCATCTCTTC TACAGTCAAG ATATCACCTA CCTCAACTTG 840

CGACATAACT TCATGCAACT AGAAAGGCCA GGGGGCCTTG ACACTCTTTA CAAATTTTCT 900

CATCTGAAGG GCCTGAACTT GTCCCATAAC AAACTTGGGT TGTTTCCTGT ATTGTTATGT 960

GAGATTTCTA CCCTGACTGA GCTAAATCTT TCCTGTAATG GATTTCACGA CCTGCCAAGT 1020

CAGATTGGCA ATCTCCTAAA TCTTCAAACT CTCTGTCTTG ATGGCAACTT TCTGACTACT 1080

TTGCCTGAAG AATTGGGAAA TCTGCAACAG CTTTCCTCCC TTGGAATTTC CTTCAACAAC 1140

TTCAGTCACA TTCCCGAGGT GTATGAGAGA CTCACCATGT TAGACAAAGT GGTTATGGCA 1200

GGAAATCAAC TGGAAGTCCT AAACCTAGGG GTGCTGAGCA GGATGAGCCA TATCAAGCAC 1260

GTAGACTTGA GAATATTAAG GATGAACCAT TTGAAAACCG TGGTAATTGA AAATCTGGAG 1320

GGAAATAAAT ACATCACCCA CATGGACTTG CGGGACAACC AACTGACTGA CTTAGATCTT 1380

AGCTCCTTCT GTAGCTTGGA GCAGCTGCAT TGTGAGCGGA ACCAGCTGAG GGAGCTGACA 1440

CTCAGTGGCT TCTCCCTGCG GACTCTCTAC GCCAATTCCA ACAGGCTGAC AGCAGTGAAT 1500

GTCTATCCAG TACCCAGTCT TCTCACATCT CTAGAACTTT CCAGAAACCA GCTGGAATGT 1560

GTCCCTGACT GGGCCTGTGA AGCAAAGAAG ATAGAAGTAT TAGATGTGAG CTATAATCTT 1620

CTGACAGAGG GTCCTATGAG AATTCTTAGC AGCCTGAGTC TTAGGAAACT GATGGTGGGA 1680

CACAATCACG TGCAGACCCT CCCAGTGCTC GTGGAGCACA TCCCTCTGGA GGTGTTGGAC 1740

ATCCAGCATA ACCTGCTCAC CAGGCTGCCG GACACCCTCT TCTCCAAGGC CTTAAACCTC 1800

AGGTACTTGA ATGCATCTGC AAATAGTCTG GAGTCCTTGC CATCTGCTTC TGCAGGGGAG 1860

GAGAGCCTGA GTGCCCTGCA GCTGCTCTAT CTGACCAACA ACCTCCTGAC AGATCAGTGT 1920

GTGCCTGTCC TGGTCGGGCA CCCACACCTG CGAATCTTGC ATCTTGCAAA CAACCAGCTA 1980

CAAACTTTTC CCGCAAGCAA ACTAAATAAA TTGGAACAAT TGGAGGAACT GAACCTAAGT 2040

GGCAACAAGC TTAAAACCAT TCCCACGACC ATAGCGAACT GCAAAAGGCT GCACACCCTT 2100

GTCGCACACT CCAACAACAT CAGCATTTTC CCAGAAATAC TGCAGTTGCC TCAGATCCAG 2160

TTTGTAGACC TAAGTTGCAA TGACTTGACA GAAATCCTGA TCCCAGAGGC CTTGCCTGCT 2220

ACCTTACAGG ACCTTGACCT GACTGGAAAT ACAAACCTGG TTCTGGAACA TAAGACGCTA 2280

GACACATTTA GCCATATCAC AACCCTGAAA ATTGATCAGA AACCTTTGCC AACCACGGAT 2340

CCTACAGTTA CATCAACTTT CTGGAGCCAT GGACTGGCTG AGATGGCAGG GCAGAGGAAC 2400

AAGCTGTGTG TATCTTCGCT AGCTGTGGAT ACCTTTGCGG AGGGCGTGGG AGCGGTATAC 2460

GGCATGTTTG ATGGGGACCG GAATGAGGAG CTTCCCCGCC TCCTGCAGTG CACGATGGCG 2520

GACGTGCTTC TGGAGGAGGT CCAGCAGTCA TCCAGTGACA CCGTTTCCAT GGCTCACACC 2580

TTCTTGGTAT CTCACAGGAA ATTAGGGATG GCTGGTCAGA AGCTGGGCTC CTCTGCTCTT 2640

CTTTGTTACA TCCGCCCTGA CACTGCCGAT TCAACAAGTA GTTTTAGCTT GACGGTGGCC 2700

AACGTGGGCA CGTGCCAAGC AGTCCTGTGT CGAGGTGGGA AACCAGTGCC CCTCTCTAAA 2760

GTCTTCAGCC TGGAACAGGA TGCGGACGAG GCCCAAAGAG TGAAAGACCA AAAAGCCATC 2820

ATAACAGAGG ATAACAAAGT GAATGGGGTA ACCTGCTGCA CCCGGATGCT GGGCTGTACA 2880

TACCTCTACC CTTGGATCCT CCCCAAGCCC TACATCTCTT CCACTACACT TACCATTCAG 2940

GATGAGTTGC TGATTCTGGG AAACAAAGCA TTGTGGGAAC ACTTGTCATA TACAGAAGCT 3000

GTCAGTGCAG TGCGTCACGT ACAAGACCCA TTAGCAGCTG CCAAGAAGCT GTGCACATTA 3060

GCCCAGAGCT ACGGTTGTCA GGACAATGTG GGGGCAATAG TGGTTTATTT GAACATTGGG 3120

GAGGAAGGCT GCACTTGTGA GATGAATGGG CTCAGCCTCC CAGGTCCTGT GGGATTTGCT 3180

CCGACCACCA CCATCAAGGA CCCTCTCAAG CCAACCACTC CTTCCTCCAG CAGTGGGATC 3240

GCCTCTGAGT TTAGCAGTGA GATGTCCACG TCAGAGGTGA GCAGTGAGGT GGGATCCACT 3300

GCTTCTGATG AACATAACAC TGCTGGCCTG GATGCCAGCT TGCTCCCACG GCCAGAGAGG 3360

CGCTGCAGCC TCCATCCCAC CCCCACCTCT GTGGTGTTTC AGCGCCAGCC TTCGTGTGCG 3420

ACTTTCTCGA GTAACCAGTC TGACAATGGC CTGGACAGTG ACGACGACCA GCCCGTTGAA 3480

GGGGTCATAA CCAATGGCAG CAAAGTAGAA GTGGAAGTGG ATATCCACTG CTGTCGGGGG 3540

AGGGAGAACT CGCCCACGCT CCCAAAGAAT TCTCCCGCCC CACGTCCTGA GGAGCATGGG 3600

AGAGGATTGT TTTTTGGGAT CCGAAGACAG AACAGTGTGA ACAGTGGCAT ACTTCTGCCA 3660

ATGAGCAAGG ACAAGATGGA GCTACAGAAG TCTCCCTCCA CCTCCTGTCT CTATGGGAAG 3720

AAACTCTCCA ATGGCTCGAT TGTACCCCTG GAAGACAGCC TGAACCTCAT TGAAGTGGCC 3780

ACAGAAGCAC CCAAGAAGAA AACGGGCTAT TTTGCTGCCC CCACTCAGCT GGAGCCAGAG 3840

GATCAGTTTG TTGTACCTCG TGACCTGGAA GAAGAAGTGA AGGAGCAAAT GAAGCAACAC 3900

CAGGAAAGCA GGCCCGAGCC TGAGCTGATT GAAGAGGATC GGACCGAGCT CCCTGAGGAG 3960

TTTGACACAG CACTGTAA 3978

Domain Profile

S: 2     lvgvvsvngrrnemedavtsspnflkspekkdrlaffgvyDGhggsevakfcseklheil  61

         ++g++++ g+rn+++ ++ +++ f++  +     a++g++DG++++e  + +++++ ++l

Q: 789   SHGLAEMAGQRNKLCVSSLAVDTFAEGVG-----AVYGMFDGDRNEELPRLLQCTMADVL  843

         6899******************9999877.....59************************

S: 62    aeelesseseerkvkkalakaFlstdeelkvleeksldidksGstavvalikds......  115

          ee++  +s+++ v+  +a++Fl  +++l       ++ +k Gs+a++++i+++

Q: 844   LEEVQ--QSSSDTVS--MAHTFLVSHRKL------GMAGQKLGSSALLCYIRPDtadsts  893

         ***99..67777777..************......89***************999999**

S: 116   ..klyvanvGdSravLcrngkavelssdHkpsre.dEleRieeaggsvilkdgaRvlGvL  172

           +l+vanvG ++avLcr+gk+v+ls+ ++ +++ dE +R++++++ +++++  +v+Gv+

Q: 894   sfSLTVANVGTCQAVLCRGGKPVPLSKVFSLEQDaDEAQRVKDQKAIITEDN--KVNGVT  951

         *******************************9988**********9999998..******

S: 173   avsRalGdlylkpyvtpePevtshrltsedefliLasDGlwdvvsneeavslvrdvlekk  232

         +++R+lG++yl+p++ p+P ++s++lt +de liL+ + lw+++s  eavs+vr+v +

Q: 952   CCTRMLGCTYLYPWILPKPYISSTTLTIQDELLILGNKALWEHLSYTEAVSAVRHVQD--  1009

         **********************************************************..

S: 233   eaeqeaakkLvklalargskdnvsaivv  260

           + +aakkL++la+++g++dnv aivv

Q: 1010  --PLAAAKKLCTLAQSYGCQDNVGAIVV  1035

         ..************************97

Domain Sequence
(FASTA)

SHGLAEMAGQ RNKLCVSSLA VDTFAEGVGA VYGMFDGDRN EELPRLLQCT MADVLLEEVQ 60

QSSSDTVSMA HTFLVSHRKL GMAGQKLGSS ALLCYIRPDT ADSTSSFSLT VANVGTCQAV 120

LCRGGKPVPL SKVFSLEQDA DEAQRVKDQK AIITEDNKVN GVTCCTRMLG CTYLYPWILP 180

KPYISSTTLT IQDELLILGN KALWEHLSYT EAVSAVRHVQ DPLAAAKKLC TLAQSYGCQD 240

NVGAIVV 247

Keyword

Complete proteome; Leucine-rich repeat; Reference proteome; Repeat.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Saccharomyces cerevisiae"; ?>