EPS-MYL-00022

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-MYL-00022

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPM/PP2C	292.1	4.5E-87	23	293	271

Status

Unreviewed

Ensembl Protein

ENSMLUP00000008236

UniProt Accession

G1PCS7;

Protein Name

Protein Synonyms/Alias

Gene Name

PPM1B

Gene Synonyms/Alias

PPM1B;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMLUG00000009051	ENSMLUP00000008236	ENSMLUT00000009041

Organism

Myotis lucifugus

Functional Description

Protein Length

479

Protein Sequence
(FASTA)

MGAFLDKPKT EKHNAHGAGN GLRYGLSSMQ GWRVEMEDAH TAVVGIPHGL EDWSFFAVYD 60

GHAGSRVANY CSTHLLEHIT NNEDFRAAAK SGSAHEPSVE NVKNGIRTGF LKIDEFMRNF 120

SDLRNGMDRS GSTAVGVMIS PKHVYFINCG DSRAVLCRNG QVCFSTQDHK PCNPREKERI 180

QNAGGSVMIQ RVNGSLAVSR ALGDYDYKCV DGKGPTEQLV SPEPEVYELL RAEDDEFIVL 240

ACDGIWDVMS NEELCDFVKS RLEVSDDLEN VCNWVVDTCL HKGSRDNMSI VLVCFPNAPK 300

VSDNAVRKDS ELDKYLESRI EEIMEKFSEE GMPDLAHVMR VLSAENIPNL PPGGGLAGKR 360

NIIEAVYSRL NPHRENDGAS DDAEESGSQG KLVEALRQMR INHRGNYRQL LEEMLSSYRL 420

AKVEGEESPA EPAAAATSSN SDAGNPVTMQ ESHTESGSDL ADLDSCNEDA GTNLGDEKV 479

Nucleotide Sequence
(FASTA)

ATGGGTGCAT TTTTGGATAA ACCCAAAACT GAGAAACATA ATGCTCATGG TGCTGGGAAT 60

GGTTTACGTT ATGGCCTGAG CAGCATGCAA GGATGGAGAG TGGAAATGGA AGACGCACAC 120

ACAGCTGTTG TAGGTATTCC TCACGGCTTG GAAGACTGGT CATTTTTTGC AGTTTATGAT 180

GGTCATGCTG GATCCCGAGT GGCAAATTAC TGCTCAACAC ATTTATTAGA ACACATCACT 240

AATAATGAAG ACTTCAGGGC AGCTGCAAAA TCAGGATCTG CTCATGAGCC TTCAGTGGAA 300

AATGTCAAGA ATGGTATCAG AACTGGCTTT TTGAAAATTG ATGAATTCAT GCGTAACTTT 360

TCAGACCTCA GAAATGGAAT GGACAGGAGT GGTTCAACTG CAGTGGGAGT TATGATTTCA 420

CCGAAGCATG TCTACTTTAT CAACTGTGGT GATTCACGTG CTGTTCTGTG TAGGAATGGA 480

CAAGTCTGCT TTTCCACCCA GGATCACAAG CCTTGCAATC CAAGGGAGAA GGAGCGTATC 540

CAAAATGCAG GAGGCAGCGT AATGATACAG CGTGTTAATG GTTCATTAGC AGTGTCTCGT 600

GCTCTGGGGG ACTATGATTA CAAGTGTGTT GATGGCAAGG GCCCAACAGA ACAACTAGTT 660

TCTCCAGAGC CTGAGGTTTA TGAACTTTTA AGAGCAGAAG ATGATGAATT TATCGTTTTG 720

GCTTGTGATG GGATCTGGGA TGTTATGAGT AATGAGGAGC TCTGTGATTT TGTTAAATCT 780

AGGCTTGAGG TATCTGATGA CCTGGAAAAT GTGTGCAATT GGGTAGTGGA CACTTGTTTA 840

CATAAGGGAA GTCGCGATAA CATGAGTATT GTACTAGTTT GCTTTCCAAA TGCCCCCAAG 900

GTCTCAGATA ATGCAGTGAG AAAAGATTCA GAGTTGGATA AGTACTTGGA ATCACGGATT 960

GAAGAAATTA TGGAGAAGTT TAGTGAGGAA GGAATGCCTG ATCTTGCCCA TGTCATGCGC 1020

GTCTTGTCTG CAGAAAATAT CCCAAATTTG CCTCCTGGAG GAGGTCTTGC TGGCAAGCGC 1080

AATATTATTG AAGCTGTTTA TAGTAGGCTG AATCCACATA GAGAAAATGA TGGGGCCTCC 1140

GATGATGCAG AGGAGAGTGG ATCACAGGGA AAATTGGTGG AAGCTCTCAG GCAAATGAGA 1200

ATTAATCATA GGGGAAACTA CCGACAACTT CTGGAGGAGA TGCTGTCTAG TTACAGGCTA 1260

GCTAAAGTAG AGGGAGAAGA AAGCCCTGCT GAACCAGCTG CTGCAGCTAC TTCCTCGAAC 1320

AGTGATGCTG GAAACCCAGT GACAATGCAG GAAAGCCATA CTGAATCAGG AAGTGACCTT 1380

GCTGACTTAG ACAGCTGTAA TGAAGATGCA GGGACAAACT TGGGTGATGA AAAAGTATGA 1440

Domain Profile

S: 2     lvgvvsvngrrnemedavtsspnflkspekkdrlaffgvyDGhggsevakfcseklheil  61

         ++g++s++g+r emeda+t++ ++    + +d ++ff+vyDGh+gs+va++cs++l e++

Q: 23    RYGLSSMQGWRVEMEDAHTAVVGIPH--GLED-WSFFAVYDGHAGSRVANYCSTHLLEHI  79

         69****************98555444..4434.***************************

S: 62    aeele.........sseseerkvkkalakaFlstdeelkvleeksldidksGstavvali  112

         +++ +         ++e++ ++vk+ ++++Fl++de ++++++ ++ +d+sGstav ++i

Q: 80    TNNEDfraaaksgsAHEPSVENVKNGIRTGFLKIDEFMRNFSDLRNGMDRSGSTAVGVMI  139

         ***99*********9*********************************************

S: 113   kdsklyvanvGdSravLcrngkavelssdHkpsredEleRieeaggsvilkdgaRvlGvL  172

         +++++y++n+GdSravLcrng+++  ++dHkp +++E+eRi++aggsv+ +   Rv+G+L

Q: 140   SPKHVYFINCGDSRAVLCRNGQVCFSTQDHKPCNPREKERIQNAGGSVMIQ---RVNGSL  196

         ***************************************************...******

S: 173   avsRalGdlylk.........pyvtpePevtshrltsedefliLasDGlwdvvsneeavs  223

         avsRalGd+++k         ++v+pePev++  + ++def++La+DG+wdv+snee+++

Q: 197   AVSRALGDYDYKcvdgkgpteQLVSPEPEVYELLRAEDDEFIVLACDGIWDVMSNEELCD  256

         ************************************************************

S: 224   lvrdvlekkeaeqeaakkLvklalargskdnvsaivv  260

         +v+++le +++++++++ +v+++l++gs+dn+s+++v

Q: 257   FVKSRLEVSDDLENVCNWVVDTCLHKGSRDNMSIVLV  293

         ********************************98875

Domain Sequence
(FASTA)

RYGLSSMQGW RVEMEDAHTA VVGIPHGLED WSFFAVYDGH AGSRVANYCS THLLEHITNN 60

EDFRAAAKSG SAHEPSVENV KNGIRTGFLK IDEFMRNFSD LRNGMDRSGS TAVGVMISPK 120

HVYFINCGDS RAVLCRNGQV CFSTQDHKPC NPREKERIQN AGGSVMIQRV NGSLAVSRAL 180

GDYDYKCVDG KGPTEQLVSP EPEVYELLRA EDDEFIVLAC DGIWDVMSNE ELCDFVKSRL 240

EVSDDLENVC NWVVDTCLHK GSRDNMSIVL V 271

Keyword

Complete proteome; Hydrolase; Magnesium; Metal-binding; Protein phosphatase; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>

Gene Ontology

GO:0000287	; F:magnesium ion binding
GO:0030145	; F:manganese ion binding
GO:0004722	; F:protein serine/threonine phosphatase activity
GO:0006470	; P:protein dephosphorylation

KEGG

InterPros

IPR001932	; PP2C-like.
IPR012911	; PP2C_C.
IPR000222	; PP2C_Mn2_Asp60_BS.
IPR015655	; Protein_Pase_2C.

Pfam

PF00481	; PP2C; 1.
PF07830	; PP2C_C; 1.

SMARTs

SM00331	; PP2C_SIG; 1.
SM00332	; PP2Cc; 1.

Prosites

PS01032

; PP2C; 1.

Prints

Created Date

20-Feb-2013