EKS-MYL-00283

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-MYL-00283

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
TKL/STKR	445.9	6.1E-134	234	521	288

Status

Unreviewed

Ensembl Protein

ENSMLUP00000009075

UniProt Accession

G1PEW7;

Protein Name

Protein Synonyms/Alias

Gene Name

BMPR1A

Gene Synonyms/Alias

BMPR1A;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMLUG00000009947	ENSMLUP00000009075	ENSMLUT00000009954

Organism

Myotis lucifugus

Functional Description

Protein Length

532

Protein Sequence
(FASTA)

MTQLYVYVTL LGAYLSVVSH VQGQNLDSML HGTGMKSDSD QKKSESGVTL APEDTLPFLK 60

CYCSGHCPDD AVNNTCITNG HCFAIIEEDD QGETTLASGC MKYEGSDFQC KDSPKAQLRR 120

TIECCRTNLC NQYLQPTLPP VVIGPFLDGS IRWLVVLISM AICIIAMIIF SSCFCYKHYC 180

KSISTRRRYN RDLEQDEAFI PAGESLKDLI DQSQSSGSGS GLPLLVQRTI AKQIQMVRQV 240

GKGRYGEVWM GKWRGEKVAV KVFFTTEEAS WFRETEIYQT VLMRHENILG FIAADIKGTG 300

SWTQLYLITD YHEHGSLYDF LKCTTLDTRA LLKLAYSAAC GLCHLHTEIY GTQGKPAIAH 360

RDLKSKNILI KKNGSCCIAD LGLAVKFNSD TNEVDVPLNA RVGTRRYMAP EVLDESLNKN 420

HFQPYIMADI YSFGLIIWEM ARRCITGGIV EEYQLPYYNM VPSDPSYEDM REVVCVKRLR 480

PIVSNRWNSD ECLRAVLKLM SECWAHNPAS RLTALRIKKT LAKMVESQDV KI 532

Nucleotide Sequence
(FASTA)

ATGACTCAGC TATATGTTTA TGTCACATTA TTGGGAGCCT ATCTGTCCGT CGTTTCTCAT 60

GTTCAAGGGC AGAATCTAGA CAGTATGCTC CATGGCACTG GGATGAAATC AGACTCTGAC 120

CAGAAGAAGT CAGAAAGTGG AGTCACCTTA GCCCCGGAAG ACACCCTGCC TTTTCTGAAG 180

TGCTACTGCT CGGGCCACTG CCCCGATGAT GCTGTCAACA ACACGTGCAT AACTAATGGG 240

CATTGCTTTG CCATCATAGA AGAAGATGAC CAGGGAGAAA CCACATTAGC TTCAGGATGT 300

ATGAAATATG AAGGATCTGA TTTTCAGTGC AAGGATTCAC CAAAAGCCCA GCTTCGCCGG 360

ACAATAGAAT GTTGTCGGAC CAATTTATGT AACCAGTATT TACAACCTAC ACTGCCCCCT 420

GTTGTTATAG GTCCGTTTCT GGATGGCAGC ATTCGATGGC TGGTGGTGCT CATTTCTATG 480

GCTATCTGCA TAATTGCTAT GATCATCTTC TCCAGCTGCT TTTGTTACAA ACATTATTGC 540

AAGAGCATCT CAACCAGACG TCGTTACAAT CGTGACTTGG AGCAGGATGA AGCGTTTATC 600

CCCGCGGGAG AGTCCCTGAA AGACCTCATT GACCAGTCGC AGAGCTCTGG CAGCGGCTCC 660

GGGCTGCCTT TGCTGGTTCA GCGAACTATT GCCAAACAGA TTCAGATGGT TCGGCAAGTT 720

GGTAAAGGTC GATATGGAGA AGTGTGGATG GGTAAATGGC GTGGTGAGAA GGTGGCAGTC 780

AAAGTGTTCT TTACCACTGA AGAAGCTAGC TGGTTTCGTG AGACGGAGAT CTACCAGACA 840

GTGCTGATGC GCCATGAAAA CATACTCGGT TTTATAGCCG CAGACATTAA AGGCACCGGC 900

TCCTGGACGC AGCTGTATCT GATCACCGAT TACCATGAGC ACGGATCTCT CTATGACTTC 960

CTGAAGTGTA CGACGCTGGA CACCAGGGCC CTGCTCAAGC TGGCGTACTC AGCTGCCTGT 1020

GGTCTGTGCC ACCTGCACAC GGAGATTTAC GGCACCCAAG GGAAGCCCGC AATTGCTCAT 1080

CGAGACCTAA AGAGCAAAAA CATTCTCATT AAGAAAAATG GAAGTTGTTG TATTGCTGAC 1140

CTGGGCCTTG CAGTTAAGTT CAATAGCGAC ACAAATGAAG TGGACGTGCC CTTGAACGCC 1200

AGAGTGGGCA CCCGGCGGTA CATGGCCCCG GAAGTGCTGG ACGAGAGCCT CAACAAGAAC 1260

CACTTCCAGC CCTACATCAT GGCGGACATC TACAGCTTCG GCCTGATCAT CTGGGAGATG 1320

GCTCGGCGCT GCATCACAGG GGGAATAGTA GAGGAGTACC AACTGCCATA TTACAACATG 1380

GTGCCCAGTG ACCCATCGTA CGAAGATATG CGTGAGGTTG TGTGTGTCAA ACGTTTGCGG 1440

CCAATTGTGT CTAATAGATG GAACAGTGAT GAGTGTCTTC GAGCAGTGCT GAAGCTGATG 1500

TCAGAATGCT GGGCCCACAA CCCGGCCTCC AGACTCACGG CTCTGCGGAT CAAGAAGACG 1560

CTGGCAAAGA TGGTTGAATC CCAAGATGTA AAGATTTGA 1599

Domain Profile

S: 1     lklleligkGrygeVwkaklrgeevAvKifstedeaswkrEkeiyqtvllrhenilqfia  60

         +++++++gkGrygeVw++k+rge+vAvK+f+t++easw+rE+eiyqtvl+rhenil+fia

Q: 234   IQMVRQVGKGRYGEVWMGKWRGEKVAVKVFFTTEEASWFRETEIYQTVLMRHENILGFIA  293

         799*********************************************************

S: 61    adkkeedsltelllvteyhekgsLsdyLkretldveellrlalslasGlahLHeeivgtk  120

         ad+k ++s+t+l+l+t+yhe+gsL+d+Lk +tld++ ll+la+s+a+Gl+hLH+ei gt+

Q: 294   ADIKGTGSWTQLYLITDYHEHGSLYDFLKCTTLDTRALLKLAYSAACGLCHLHTEIYGTQ  353

         ************************************************************

S: 121   gkkKpaiaHRDlkskNilvkkdltcciaDlGLalkleeekeeldlaansqvGtkRYmaPE  180

         g  KpaiaHRDlkskNil+kk+++cciaDlGLa+k++++++e+d+  n +vGt+RYmaPE

Q: 354   G--KPAIAHRDLKSKNILIKKNGSCCIADLGLAVKFNSDTNEVDVPLNARVGTRRYMAPE  411

         *..*********************************************************

S: 181   vleealnlkdfeafkraDvYslgLvlWEvasRceevdeeveeyklpfeevvgsdPsleem  240

         vl+e+ln ++f+ + +aD+Ys+gL++WE+a+Rc + +++veey+lp++++v+sdPs+e+m

Q: 412   VLDESLNKNHFQPYIMADIYSFGLIIWEMARRCIT-GGIVEEYQLPYYNMVPSDPSYEDM  470

         ***********************************.************************

S: 241   kevvvekklrPkipeawkkkealkelsklleecWdadpeaRltalrvkkrl  291

         +evv++k+lrP ++++w+++e+l+++ kl++ecW+++p++Rltalr+kk+l

Q: 471   REVVCVKRLRPIVSNRWNSDECLRAVLKLMSECWAHNPASRLTALRIKKTL  521

         *************************************************97

Domain Sequence
(FASTA)

IQMVRQVGKG RYGEVWMGKW RGEKVAVKVF FTTEEASWFR ETEIYQTVLM RHENILGFIA 60

ADIKGTGSWT QLYLITDYHE HGSLYDFLKC TTLDTRALLK LAYSAACGLC HLHTEIYGTQ 120

GKPAIAHRDL KSKNILIKKN GSCCIADLGL AVKFNSDTNE VDVPLNARVG TRRYMAPEVL 180

DESLNKNHFQ PYIMADIYSF GLIIWEMARR CITGGIVEEY QLPYYNMVPS DPSYEDMREV 240

VCVKRLRPIV SNRWNSDECL RAVLKLMSEC WAHNPASRLT ALRIKKTL 288

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>

Gene Ontology

GO:0016020	; C:membrane
GO:0005524	; F:ATP binding
GO:0005024	; F:transforming growth factor beta-activated receptor activity
GO:0007178	; P:transmembrane receptor protein serine/threonine kinase signaling pathway

KEGG

InterPros

IPR000472	; Activin_rcpt.
IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR008271	; Ser/Thr_kinase_AS.
IPR003605	; TGF_beta_rcpt_GS.

Pfam

PF01064	; Activin_recp; 1.
PF00069	; Pkinase; 1.
PF08515	; TGF_beta_GS; 1.

SMARTs

SM00467

; GS; 1.

Prosites

PS51256	; GS; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013