EKS-MYL-00290

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-MYL-00290

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/IRE	433.0	4.2E-130	392	653	262

Status

Unreviewed

Ensembl Protein

ENSMLUP00000011096

UniProt Accession

G1PJZ9;

Protein Name

Protein Synonyms/Alias

Gene Name

ERN2

Gene Synonyms/Alias

ERN2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMLUG00000012167	ENSMLUP00000011096	ENSMLUT00000012180

Organism

Myotis lucifugus

Functional Description

Protein Length

796

Protein Sequence
(FASTA)

QKLPFTIPEL VHASPCRSSD GVFYTGRKQD AWFVVDPESG ETQMTLTTEG TSAPRLYIGR 60

TQYTVTMQDP QAPGQRWNTT YRRYSAPPMD GSPGNVSAAF LWSSVPNSGI PEWHPNPDHL 120

LDIMTVLPDF LIYLTGAPGH PLVPCATETA TTTTHPSPPL PTRMTLYIGK DDAGFYVSKA 180

LVHTGVALVP RGLTLASMDG PTTDEVTLQV SGEREGSPST AVRYPSGSVA LPSQWLLIGH 240

HEPPPVLHTT MLRVHPTPGS RTAETRPSKS KQAPALLMEL LSLSREELWD LELHPEENTA 300

DLYLGLGPQD LLVASLTAVL LGGWILFLMR QQQQLAGSPS EQTQLLEDPE GELNACYVIE 360

HSRKFKKPAG QAEPPHGREQ AEQLTVVGKI SFNPKDVLGR GAGGTFVFRG QFEGRAVAVK 420

RLLRECFGLV RREVQLLQES DRHPNVLRYF CTERGPQFYY IALELCPASL QEYVENPELD 480

CWGLEPETAL QHLMSGLAHL HSLHIVHRDL KPTNVLITGP EGQGRGRVVL SDFGLCKKLA 540

AGRCSFSLRS GVPGTEGWMA PELLQLPPPD SPTSAVDIFS AGCVFYYVLS SGSHPFGENL 600

YRQANILAGA PCLAHLEEEA HDKVAARSLV EAMLSPQPQA RPSAQQVLAH PFFWSRAKQL 660

QFFQDVSDWL EKESEQGPLV MALEAGGSAV VRGNWHKHIT VPLQTDLRRF RSYKGTSVRD 720

LLRAMRNKKH HYRELPGEVR QALGQVPDSF VQYFTDRFPR LLLHTHQAMR SCASESLFLP 780

YYPPAPGTRE PCAGAA 796

Nucleotide Sequence
(FASTA)

CAGAAACTGC CGTTCACCAT CCCCGAGCTG GTCCACGCCT CCCCGTGCCG CAGCTCCGAT 60

GGCGTCTTCT ATACGGGCCG AAAGCAGGAT GCCTGGTTTG TGGTGGACCC GGAGTCAGGG 120

GAGACACAGA TGACACTGAC CACAGAGGGC ACCTCTGCGC CCCGCCTCTA CATCGGCCGC 180

ACGCAGTACA CGGTCACCAT GCAGGACCCC CAGGCCCCCG GCCAGCGCTG GAACACCACC 240

TACCGCCGCT ACTCAGCGCC CCCCATGGAC GGCTCCCCTG GAAATGTGAG TGCCGCCTTT 300

CTCTGGAGCA GTGTCCCCAA CTCAGGGATC CCTGAGTGGC ATCCTAATCC TGACCACCTC 360

CTTGATATTA TGACTGTCCT ACCAGACTTC CTGATTTACC TCACAGGTGC CCCTGGGCAC 420

CCCCTGGTTC CCTGTGCAAC GGAAACAGCC ACAACCACTA CTCATCCCTC TCCTCCTCTC 480

CCCACTAGGA TGACGCTGTA TATAGGGAAG GATGATGCTG GCTTCTATGT TTCCAAAGCC 540

CTGGTTCACA CAGGGGTGGC CTTGGTGCCT CGTGGACTGA CCCTGGCCTC CATGGATGGC 600

CCCACCACAG ATGAGGTGAC ACTTCAAGTC TCAGGAGAGC GAGAGGGCTC ACCTAGCACA 660

GCTGTCAGAT ACCCCTCAGG CAGTGTGGCC CTCCCTAGCC AGTGGCTGCT CATTGGACAC 720

CATGAGCCAC CCCCAGTCCT GCACACCACG ATGCTGAGAG TCCATCCTAC CCCAGGGAGT 780

AGAACTGCTG AAACTAGACC CTCCAAGAGC AAGCAGGCCC CAGCCCTCTT AATGGAGCTC 840

CTGAGTCTGA GTCGGGAGGA ACTTTGGGAC CTGGAGCTGC ACCCTGAAGA GAACACCGCA 900

GACTTGTATC TAGGACTGGG ACCCCAAGAC CTGCTGGTGG CCAGCCTCAC TGCAGTCCTC 960

CTGGGAGGGT GGATTCTCTT CTTAATGAGG CAGCAGCAGC AGCTGGCGGG AAGCCCCTCT 1020

GAGCAAACCC AGCTGCTTGA AGACCCTGAA GGTGAGCTTA ATGCCTGCTA TGTAATTGAG 1080

CACTCTAGAA AGTTTAAAAA ACCAGCCGGC CAAGCAGAGC CGCCGCATGG AAGGGAACAG 1140

GCTGAGCAGC TCACTGTGGT GGGGAAGATC TCCTTTAACC CCAAGGATGT GCTGGGCCGC 1200

GGGGCAGGCG GGACTTTCGT TTTCCGGGGA CAGTTTGAGG GGCGGGCAGT GGCTGTCAAG 1260

CGACTCCTTC GTGAATGCTT TGGCCTGGTG CGGCGGGAGG TCCAGCTGCT CCAAGAGTCA 1320

GACCGGCACC CCAACGTGCT CCGCTACTTC TGTACAGAGC GGGGACCCCA GTTCTACTAC 1380

ATCGCCCTGG AGCTCTGCCC CGCCTCCTTG CAGGAGTACG TGGAAAACCC AGAGCTGGAC 1440

TGCTGGGGCC TGGAGCCGGA GACAGCGCTG CAGCACCTCA TGTCTGGCCT GGCCCACCTG 1500

CATTCTCTAC ACATAGTGCA CCGGGACCTG AAGCCAACCA ACGTGCTCAT CACGGGGCCT 1560

GAGGGCCAGG GCCGAGGCAG GGTGGTCCTC TCGGACTTCG GCCTGTGCAA GAAGCTGGCA 1620

GCCGGCCGCT GTAGCTTCAG CCTGCGCTCA GGTGTCCCCG GCACAGAGGG CTGGATGGCA 1680

CCTGAGCTCC TGCAGCTCCC GCCCCCCGAC AGTCCGACCA GCGCGGTGGA CATCTTCTCT 1740

GCAGGCTGCG TGTTCTACTA CGTGCTTTCC AGCGGCAGCC ACCCCTTTGG AGAGAATCTT 1800

TATCGCCAGG CAAACATCCT TGCAGGCGCT CCCTGTCTGG CTCACCTGGA GGAAGAGGCC 1860

CATGACAAGG TGGCTGCCCG GAGCCTGGTG GAGGCCATGC TGAGCCCTCA GCCGCAGGCG 1920

CGCCCCTCTG CTCAGCAGGT GCTGGCCCAC CCCTTCTTTT GGAGCAGAGC CAAGCAGCTC 1980

CAGTTCTTCC AGGACGTCAG TGACTGGCTG GAGAAAGAGT CCGAACAGGG GCCCCTGGTG 2040

ATGGCGCTGG AGGCAGGAGG CTCCGCCGTG GTCCGGGGCA ACTGGCACAA GCACATCACG 2100

GTGCCGCTGC AGACAGATCT GCGACGGTTC CGGTCCTATA AGGGGACCTC GGTGCGAGAC 2160

CTGCTCCGAG CCATGAGGAA CAAGAAGCAC CACTACAGGG AGCTCCCGGG TGAGGTCCGG 2220

CAGGCGCTCG GCCAGGTCCC CGACAGCTTT GTCCAGTACT TCACAGACCG CTTCCCGCGG 2280

CTGCTGCTCC ACACGCACCA GGCCATGAGG AGCTGCGCCT CCGAGAGCCT CTTCTTGCCC 2340

TATTACCCGC CGGCCCCAGG GACCAGGGAG CCATGTGCAG GAGCTGCT 2388

Domain Profile

S: 1     fspkdvlGkGaeGtvvfrGsfegrevavkrllsefvdlakrevkllresdehpnviryfc  60

         f+pkdvlG+Ga+Gt+vfrG+fegr+vavkrll+e++ l++rev+ll+esd+hpnv+ryfc

Q: 392   FNPKDVLGRGAGGTFVFRGQFEGRAVAVKRLLRECFGLVRREVQLLQESDRHPNVLRYFC  451

         799*********************************************************

S: 61    tekdrqfryialelcaaslqdyvedkdlelqkelepisllkqiasGlahlhslkivhrdl  120

         te+++qf yialelc aslq+yve+++l+  ++lep + l+ ++sGlahlhsl+ivhrdl

Q: 452   TERGPQFYYIALELCPASLQEYVENPELD-CWGLEPETALQHLMSGLAHLHSLHIVHRDL  510

         *****************************.9*****************************

S: 121   kpqnilislpdakgklrvlisdfGlckkldvGkssfsrrsgvsGteGwiapelleeltke  180

         kp+n+li+ p+++g+ rv++sdfGlckkl++G++sfs rsgv+GteGw+apell+  +++

Q: 511   KPTNVLITGPEGQGRGRVVLSDFGLCKKLAAGRCSFSLRSGVPGTEGWMAPELLQLPPPD  570

         ************************************************************

S: 181   rltsavdifslGcvfyyvlskGkhpfGdslkrqanilsgelsldklkeekdeeviaedli  240

         ++tsavdifs+Gcvfyyvls+G+hpfG++l+rqanil g+ +l++l+ee +++v a+ l+

Q: 571   SPTSAVDIFSAGCVFYYVLSSGSHPFGENLYRQANILAGAPCLAHLEEEAHDKVAARSLV  630

         ************************************************************

S: 241   skmidkdplkrpsakkvlkhplf  263

         ++m++ +p+ rpsa++vl+hp+f

Q: 631   EAMLSPQPQARPSAQQVLAHPFF  653

         **********************9

Domain Sequence
(FASTA)

FNPKDVLGRG AGGTFVFRGQ FEGRAVAVKR LLRECFGLVR REVQLLQESD RHPNVLRYFC 60

TERGPQFYYI ALELCPASLQ EYVENPELDC WGLEPETALQ HLMSGLAHLH SLHIVHRDLK 120

PTNVLITGPE GQGRGRVVLS DFGLCKKLAA GRCSFSLRSG VPGTEGWMAP ELLQLPPPDS 180

PTSAVDIFSA GCVFYYVLSS GSHPFGENLY RQANILAGAP CLAHLEEEAH DKVAARSLVE 240

AMLSPQPQAR PSAQQVLAHP FF 262

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Felis catus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Ochotona princeps"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Takifugu rubripes"; ?>Tupaia belangeri"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0016891	; F:endoribonuclease activity, producing 5'-phosphomonoesters
GO:0004674	; F:protein serine/threonine kinase activity
GO:0006397	; P:mRNA processing

KEGG

InterPros

IPR010513	; KEN_RNase_activator.
IPR011009	; Kinase-like_dom.
IPR018391	; PQQ_beta_propeller_repeat.
IPR000719	; Prot_kinase_cat_dom.
IPR006567	; PUG-dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069	; Pkinase; 1.
PF06479	; Ribonuc_2-5A; 1.

SMARTs

SM00564	; PQQ; 2.
SM00580	; PUG; 1.

Prosites

PS51392	; KEN; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013