EKS-MYL-00241

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-MYL-00241

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/CAMKL	366.0	8.6E-110	26	277	252

Status

Unreviewed

Ensembl Protein

ENSMLUP00000011163

UniProt Accession

G1PK61;

Protein Name

Protein Synonyms/Alias

Gene Name

MARK4

Gene Synonyms/Alias

MARK4;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMLUG00000012252	ENSMLUP00000011163	ENSMLUT00000012257

Organism

Myotis lucifugus

Functional Description

Protein Length

786

Protein Sequence
(FASTA)

SSRSLGARCR NSIASCPEEQ PHVGNYRLLR TIGKGNFAKV KLARHILTGR EVAIKIIDKT 60

QLNPSSLQKL FREVRIMKGL NHPNIVKLFE VIETEKTLYL VMEYASAGEV FDYLEHTGPR 120

RRRKLRDKFR QIVSAVHYCH QKNIVHRDLK AENLLLDAEA NIKIADFGFS NEFTLGSKLD 180

TFCGSPPYAA PELFQGKKYD GPEVDIWSLG VILYTLVSGS LPFDGHNLKE LRERVLRGKY 240

RVPFYMSTDC ESILRRFLVL NPAKRCTLEQ IMKDKWINIG YEGEELKPYT EPEEDFGDTK 300

RIEVMVGMGY TREEIKEALT SQKYNEVTAT YLLLGRKTEE GGDRGAPALA LARVRAPSDT 360

TNGTSSGKGT SHSKGQRSSS STYHRQRRHS DFCGPSPTPL HPKRSPTSTG EAELKEERLP 420

SRKASCSAAG SGSRGLPPSS PMVSSAHNPN KAEIPERRKD STSTPNNLPP SMMTRRNTYV 480

CTERPGAERP SLLPNGKENS LFQLASESSS PGVGVGGLQD SDTPAHQSSS QETSGFPLRD 540

PGWCWGPRKD GGWSWGLLSG TPRVPPASPS SHSLAPPSGE RSRLARGSTI RSTFHGGQVR 600

DRRAGGGGGG GVQNGPPASP TLAHEATPLP TGRPRPTTNL FTKLTSKLTR RDPSSGPAGG 660

RQSLTARNTL GTENPWSRVE KDQTETAPRL LRFPWSVKLT SSRPPEALMA ALRQATAAAR 720

CRCRQPQPFL LACLHGGAGG PEPLSHFEVE VCQLPRPGLR GVFRRVVGTA LVFRTLVTRI 780

SNDLEL 786

Nucleotide Sequence
(FASTA)

TCCAGCCGAT CCCTGGGTGC CCGCTGCCGG AACTCCATCG CCTCCTGCCC CGAGGAGCAG 60

CCCCACGTGG GCAACTACCG CCTGCTGAGG ACCATCGGGA AGGGCAACTT TGCCAAAGTC 120

AAGCTGGCCC GGCACATCCT CACCGGCCGG GAGGTTGCCA TCAAAATCAT CGACAAAACC 180

CAGCTGAACC CCAGCAGCCT GCAGAAGCTG TTCCGAGAAG TTCGTATCAT GAAGGGCCTA 240

AACCACCCCA ACATCGTGAA ACTCTTCGAA GTGATCGAGA CTGAGAAGAC GCTGTACCTG 300

GTGATGGAAT ATGCAAGTGC TGGAGAAGTA TTCGACTACC TCGAGCACAC TGGCCCAAGA 360

AGGAGAAGGA AGCTTCGAGA CAAGTTCCGA CAGATTGTAT CGGCTGTGCA CTACTGTCAC 420

CAGAAAAACA TTGTCCACAG GGACCTGAAG GCCGAGAACC TCTTGCTGGA CGCCGAGGCC 480

AACATCAAGA TCGCCGACTT TGGCTTCAGC AACGAGTTCA CGCTGGGCTC GAAGCTGGAC 540

ACGTTCTGCG GGAGCCCCCC GTACGCCGCC CCGGAGCTGT TCCAGGGCAA GAAGTACGAC 600

GGGCCGGAGG TGGACATCTG GAGCCTGGGC GTCATCCTGT ACACCCTCGT CAGCGGCTCC 660

CTGCCCTTCG ACGGGCACAA CCTCAAGGAG CTGCGGGAGC GAGTCCTCAG GGGGAAGTAC 720

CGGGTCCCTT TCTACATGTC TACCGACTGT GAGAGCATCC TGCGCAGATT TTTGGTGCTG 780

AACCCCGCTA AACGCTGTAC TCTGGAGCAA ATCATGAAAG ACAAATGGAT CAATATCGGC 840

TATGAGGGTG AGGAGCTGAA GCCATACACA GAGCCGGAGG AGGACTTTGG GGACACCAAG 900

CGAATCGAGG TGATGGTGGG TATGGGCTAC ACTCGGGAAG AAATCAAAGA GGCCTTGACC 960

AGCCAGAAGT ACAACGAAGT GACCGCCACC TACCTCCTGC TGGGCAGGAA GACTGAGGAG 1020

GGCGGGGACC GGGGCGCCCC AGCACTGGCC CTGGCAAGGG TGCGGGCGCC CAGCGACACC 1080

ACCAACGGGA CAAGCTCCGG CAAAGGCACC AGCCACAGCA AAGGGCAGCG GAGCTCCTCC 1140

TCCACCTACC ACCGCCAGCG CAGGCACAGC GACTTCTGCG GCCCATCCCC CACACCCCTG 1200

CACCCCAAGC GCAGCCCAAC CAGCACGGGG GAGGCGGAGC TGAAGGAGGA GCGCCTGCCG 1260

AGCCGGAAGG CGAGCTGCAG TGCTGCGGGC AGCGGGAGCC GAGGGCTGCC CCCCTCCAGC 1320

CCGATGGTCA GCAGTGCCCA CAACCCCAAC AAAGCAGAAA TCCCGGAGCG GCGGAAGGAC 1380

AGCACGAGCA CCCCTAACAA CCTCCCTCCC AGCATGATGA CCCGCAGGAA CACCTACGTT 1440

TGCACGGAAC GCCCAGGGGC TGAGCGCCCG TCCCTGTTGC CAAATGGCAA AGAAAACAGT 1500

CTCTTCCAGC TGGCGAGTGA GAGTTCAAGT CCAGGAGTCG GGGTGGGGGG ACTTCAGGAT 1560

AGTGACACTC CTGCCCACCA GAGTTCTAGT CAAGAGACAT CAGGGTTCCC TCTTAGAGAT 1620

CCAGGCTGGT GCTGGGGCCC CCGGAAGGAT GGAGGTTGGA GTTGGGGCCT CCTCTCGGGT 1680

ACCCCACGGG TGCCCCCCGC CTCCCCCTCC AGTCACAGCC TGGCTCCCCC ATCAGGGGAG 1740

CGGAGCCGCC TGGCACGGGG CTCCACCATC CGTAGCACCT TCCACGGTGG CCAGGTCCGG 1800

GACCGGCGGG CAGGGGGCGG GGGAGGTGGG GGCGTGCAGA ACGGGCCCCC TGCCTCTCCC 1860

ACACTGGCCC ACGAGGCCAC ACCCCTGCCC ACCGGGCGGC CCCGCCCCAC CACCAACCTC 1920

TTTACCAAGC TGACCTCCAA ACTGACCCGA AGGGATCCAA GCTCTGGGCC AGCTGGTGGC 1980

AGACAGAGTC TAACAGCAAG GAACACCCTT GGTACTGAGA ACCCGTGGTC TAGAGTGGAG 2040

AAGGATCAAA CGGAAACCGC CCCCCGGCTG CTCCGATTCC CCTGGAGTGT GAAGCTGACC 2100

AGCTCGCGCC CACCCGAGGC CCTGATGGCA GCTCTGCGCC AGGCCACCGC GGCCGCCCGC 2160

TGCCGCTGCC GCCAGCCACA GCCGTTCCTG CTGGCCTGCC TGCACGGGGG TGCGGGCGGG 2220

CCCGAGCCCC TGTCCCACTT CGAAGTGGAG GTCTGCCAGC TGCCCCGGCC GGGCCTGCGG 2280

GGAGTTTTCC GGCGCGTGGT GGGCACTGCC CTGGTCTTCC GCACCCTCGT CACCCGCATC 2340

TCCAACGACC TCGAGCTCTG A 2361

Domain Profile

S: 1     ykllktlGegsfgkVklakhketkekvavKiikkkklseeslekikrEieilkklkhpni  60

         y+ll+t+G+g+f+kVkla+h +t+++va+Kii+k++l+ +sl+k++rE++i+k l+hpni

Q: 26    YRLLRTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPSSLQKLFREVRIMKGLNHPNI  85

         99**********************************************************

S: 61    ikllevietkkklylvleyasggeLfdyieekgrlkekearklfkqlvsavkYlhskgiv  120

         +kl+eviet+k+lylv+eyas ge+fdy+e++g  ++++ r  f+q+vsav+Y+h+k+iv

Q: 86    VKLFEVIETEKTLYLVMEYASAGEVFDYLEHTGPRRRRKLRDKFRQIVSAVHYCHQKNIV  145

         ************************************************************

S: 121   HrDlKpeNllldkkenikiaDFGlanlfkegklletfcGsppYaaPellkgkkYegpkvD  180

         HrDlK+eNllld++ nikiaDFG++n+f+ g++l+tfcGsppYaaPel++gkkY+gp+vD

Q: 146   HRDLKAENLLLDAEANIKIADFGFSNEFTLGSKLDTFCGSPPYAAPELFQGKKYDGPEVD  205

         ************************************************************

S: 181   vWslGvvLyalvtgklPfdeenlkellekilkgkleipkklskelesLlrklLvvdpekR  240

         +WslGv+Ly+lv+g+lPfd++nlkel+e++l+gk+++p+++s+++es+lr++Lv +p+kR

Q: 206   IWSLGVILYTLVSGSLPFDGHNLKELRERVLRGKYRVPFYMSTDCESILRRFLVLNPAKR  265

         ************************************************************

S: 241   atieeilkhewl  252

         +t+e+i+k++w+

Q: 266   CTLEQIMKDKWI  277

         ***********7

Domain Sequence
(FASTA)

YRLLRTIGKG NFAKVKLARH ILTGREVAIK IIDKTQLNPS SLQKLFREVR IMKGLNHPNI 60

VKLFEVIETE KTLYLVMEYA SAGEVFDYLE HTGPRRRRKL RDKFRQIVSA VHYCHQKNIV 120

HRDLKAENLL LDAEANIKIA DFGFSNEFTL GSKLDTFCGS PPYAAPELFQ GKKYDGPEVD 180

IWSLGVILYT LVSGSLPFDG HNLKELRERV LRGKYRVPFY MSTDCESILR RFLVLNPAKR 240

CTLEQIMKDK WI 252

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona savignyi"; ?>Equus caballus"; ?>Felis catus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR001772	; Kinase-assoc_KA1.
IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.
IPR000449	; UBA/transl_elong_EF1B_N.
IPR015940	; UBA/transl_elong_EF1B_N_euk.

Pfam

PF02149	; KA1; 1.
PF00069	; Pkinase; 1.
PF00627	; UBA; 1.

SMARTs

SM00220	; S_TKc; 1.
SM00165	; UBA; 1.

Prosites

PS50032	; KA1; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.
PS50030	; UBA; 1.

Prints

Created Date

20-Feb-2013