EKS-MYL-00469

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-MYL-00469

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/CAMK2	570.2	5.4E-172	19	269	251

Status

Unreviewed

Ensembl Protein

ENSMLUP00000011643

UniProt Accession

G1PLB8;

Protein Name

Protein Synonyms/Alias

Gene Name

CAMK2G

Gene Synonyms/Alias

CAMK2G;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMLUG00000012781	ENSMLUP00000011643	ENSMLUT00000012796

Organism

Myotis lucifugus

Functional Description

Protein Length

558

Protein Sequence
(FASTA)

VCVTLLCSVS QLFPPSPSRG AFSVVRRCVK KTSTQEYAAK IINTKKLSAR DHQKLEREAR 60

ICRLLKHPNI VRLHDSISEE GFHYLVFDLV TGGELFEDIV AREYYSEADA SHCIHQILES 120

VNHIHQHDIV HRDLKPENLL LASKCKGAAV KLADFGLAIE VQGEQQAWFG FAGTPGYLSP 180

EVLRKDPYGK PVDIWACGVI LYILLVGYPP FWDEDQHKLY QQIKAGAYDF PSPEWDTVTP 240

EAKNLINQML TINPAKRITA DQALKHPWVC QRSTVASMMH RQETVECLRK FNARRKLKGA 300

ILTTMLVSRN FSAAKSLLNK KSDGGVKKRK SSSSVHLMPQ SNNKNSLVSP AQEPAPLQTA 360

MEPQTTVVHN ATDGIKGSTE SCNTTTEDED LKGNGSSVPE GRSSRDRTAP SAGMQPQPSL 420

CSSAMRKQEI IKITEQLIEA INNGDFEAYT KICDPGLTSF EPEALGNLVE GMDFHKFYFE 480

NLLSKNSKPI HTTILNPHVH VIGEDAACIA YIRLTQYIDG QGRPRTSQSE ETRVWHRRDG 540

KWLNVHYHCS GAPAAPLQ 558

Nucleotide Sequence
(FASTA)

GTCTGTGTGA CTCTACTGTG CTCCGTGTCC CAGCTCTTTC CCCCTTCTCC CTCCAGGGGT 60

GCTTTCTCTG TGGTCCGCAG GTGTGTGAAG AAAACCTCCA CGCAGGAGTA TGCAGCAAAA 120

ATCATCAATA CCAAGAAGTT GTCTGCCCGG GATCACCAGA AACTAGAACG TGAGGCCCGG 180

ATATGCCGAC TTTTGAAACA TCCAAACATT GTGCGCCTCC ACGACAGCAT TTCTGAAGAA 240

GGGTTTCACT ACCTCGTGTT TGACCTTGTT ACTGGCGGAG AGCTGTTTGA AGACATCGTG 300

GCCAGAGAAT ACTACAGTGA AGCTGATGCC AGCCACTGTA TACATCAGAT TCTGGAGAGC 360

GTTAACCACA TCCACCAGCA CGACATCGTC CACAGGGACC TGAAGCCTGA GAACCTGCTG 420

CTGGCGAGTA AATGCAAGGG TGCCGCAGTC AAGCTGGCCG ACTTTGGCCT GGCCATCGAA 480

GTCCAGGGAG AGCAGCAGGC TTGGTTTGGT TTTGCTGGCA CCCCCGGTTA CTTGTCCCCT 540

GAGGTCTTGA GGAAAGATCC CTATGGAAAA CCTGTGGATA TCTGGGCCTG CGGAGTCATC 600

CTGTATATAC TCCTGGTGGG ATACCCTCCC TTCTGGGATG AGGATCAACA CAAGCTGTAT 660

CAGCAGATCA AGGCCGGAGC CTATGATTTC CCATCACCAG AGTGGGACAC GGTGACCCCT 720

GAAGCCAAGA ACTTGATCAA CCAGATGCTG ACCATAAACC CCGCAAAACG TATCACAGCC 780

GACCAGGCCC TCAAGCACCC ATGGGTCTGC CAACGGTCCA CGGTGGCCTC CATGATGCAT 840

CGTCAGGAGA CGGTGGAGTG CTTGCGCAAG TTCAATGCCC GGAGAAAACT GAAGGGTGCC 900

ATCCTCACGA CCATGCTTGT CTCCAGGAAC TTCTCAGCTG CCAAAAGCCT ATTGAACAAG 960

AAGTCGGATG GCGGCGTCAA GAAAAGGAAG TCAAGTTCCA GCGTGCACCT AATGCCACAG 1020

AGCAACAACA AAAACAGTCT CGTAAGCCCA GCCCAAGAGC CTGCGCCCTT GCAGACGGCC 1080

ATGGAGCCTC AAACCACCGT GGTGCACAAC GCTACAGACG GGATCAAGGG CTCCACGGAG 1140

AGCTGCAACA CCACCACGGA AGATGAGGAC CTCAAAGGGA ATGGCAGCTC GGTGCCCGAA 1200

GGACGGAGCT CCCGGGACAG AACAGCCCCC TCTGCAGGCA TGCAGCCCCA GCCTTCTCTC 1260

TGCTCCTCAG CCATGCGAAA ACAGGAGATC ATTAAGATCA CAGAACAACT GATTGAGGCC 1320

ATCAACAATG GAGATTTTGA GGCCTACACG AAGATTTGTG ATCCAGGCCT CACTTCCTTT 1380

GAGCCCGAAG CCCTCGGTAA CCTCGTGGAG GGAATGGATT TCCATAAGTT TTACTTTGAG 1440

AATCTCCTGT CCAAGAACAG CAAGCCCATT CACACCACCA TCCTGAACCC GCACGTCCAT 1500

GTGATCGGAG AGGACGCCGC TTGCATCGCC TATATCCGCC TCACCCAGTA CATCGATGGG 1560

CAGGGCCGGC CTCGCACCAG CCAGTCGGAG GAGACCCGGG TCTGGCACCG CCGGGATGGC 1620

AAGTGGCTCA ATGTCCACTA TCACTGCTCA GGGGCCCCTG CCGCACCGCT GCAGTGA 1677

Domain Profile

S: 9     kgafsvvrrcvkvttgqeyaakiintkklsardhqklerearicrllkhpnivrlhdsis  68

         +gafsvvrrcvk+t++qeyaakiintkklsardhqklerearicrllkhpnivrlhdsis

Q: 19    RGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSIS  78

         8***********************************************************

S: 69    eegfhylvfdlvtggelfedivareyyseadashciqqilesvlhihqngvvhrdlkpen  128

         eegfhylvfdlvtggelfedivareyyseadashci+qilesv+hihq+++vhrdlkpen

Q: 79    EEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQHDIVHRDLKPEN  138

         ************************************************************

S: 129   lllaskakgaavkladfglaievqgdqqawfgfagtpgylspevlrkdpygkpvdlwacg  188

         lllask+kgaavkladfglaievqg+qqawfgfagtpgylspevlrkdpygkpvd+wacg

Q: 139   LLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDIWACG  198

         ************************************************************

S: 189   vilyillvgyppfwdedqhrlyqqikagaydfpspewdtvtpeakdlinkmltinpakri  248

         vilyillvgyppfwdedqh+lyqqikagaydfpspewdtvtpeak+lin+mltinpakri

Q: 199   VILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRI  258

         ************************************************************

S: 249   tadealkhpwi  259

         tad+alkhpw+

Q: 259   TADQALKHPWV  269

         **********8

Domain Sequence
(FASTA)

RGAFSVVRRC VKKTSTQEYA AKIINTKKLS ARDHQKLERE ARICRLLKHP NIVRLHDSIS 60

EEGFHYLVFD LVTGGELFED IVAREYYSEA DASHCIHQIL ESVNHIHQHD IVHRDLKPEN 120

LLLASKCKGA AVKLADFGLA IEVQGEQQAW FGFAGTPGYL SPEVLRKDPY GKPVDIWACG 180

VILYILLVGY PPFWDEDQHK LYQQIKAGAY DFPSPEWDTV TPEAKNLINQ MLTINPAKRI 240

TADQALKHPW V 251

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004683	; F:calmodulin-dependent protein kinase activity

KEGG

InterPros

IPR020636	; Ca/CaM-dep_Ca-dep_prot_Kinase.
IPR013543	; Ca/CaM-dep_prot_kinase-assoc.
IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF08332	; CaMKII_AD; 1.
PF00069	; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013