EPS-MYL-00014

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-MYL-00014

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
DSP/aDSP	91.8	3.6E-26	8	98	91

Status

Unreviewed

Ensembl Protein

ENSMLUP00000011647

UniProt Accession

G1PLC1;

Protein Name

Protein Synonyms/Alias

Gene Name

DUSP12

Gene Synonyms/Alias

DUSP12;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMLUG00000012791	ENSMLUP00000011647	ENSMLUT00000012800

Organism

Myotis lucifugus

Functional Description

Protein Length

269

Protein Sequence
(FASTA)

VEGLRRLFVP ALDEPETDLL SHLGRCVAFL GRARAEGRAA LVHCHAGVSR SVAVMTAFLM 60

KTDQLTFEKA YENLQTIKPE AKMNEGFEWQ LKLYQLMGCE VDTCSAIYKQ YRLQKVTEKY 120

PELQSLPQEL FAVDPTVVSQ GLKEEVLYKC RKCRRSLFRS SSILDHNEGS GSIAFAHKRR 180

APSLVPVTGS RAQCTSYFIE PVQWMEPALL GVMDGQLLCP KCNAKLGSFN WYGEQCSCGR 240

WITPAFQIHK NRVDEMKTLL VLGSQTRKM 269

Nucleotide Sequence
(FASTA)

GTGGAGGGCC TGCGGAGGCT CTTCGTGCCC GCACTGGACG AGCCCGAGAC CGACCTCCTG 60

AGCCACCTGG GCCGCTGCGT GGCCTTCCTG GGCCGGGCCC GCGCCGAGGG CCGCGCGGCG 120

CTGGTGCACT GTCATGCAGG AGTCAGCCGC AGTGTGGCTG TAATGACTGC TTTTCTGATG 180

AAGACTGACC AACTTACCTT TGAAAAAGCC TATGAAAACC TCCAGACTAT CAAACCAGAG 240

GCCAAGATGA ATGAGGGTTT TGAGTGGCAA CTGAAATTAT ACCAGCTCAT GGGATGCGAA 300

GTCGATACCT GTAGTGCAAT TTATAAGCAA TATCGTTTGC AAAAGGTTAC AGAGAAGTAT 360

CCGGAGCTGC AGAGCTTACC TCAAGAACTC TTTGCTGTTG ACCCAACTGT GGTTTCACAA 420

GGATTGAAAG AGGAGGTTCT CTACAAATGT AGAAAGTGCA GGAGGTCTTT ATTTCGAAGT 480

TCGAGCATTT TGGATCATAA TGAAGGAAGT GGCTCCATAG CCTTTGCCCA CAAGAGACGG 540

GCACCATCCC TCGTGCCTGT CACGGGGAGT CGGGCTCAGT GCACATCCTA TTTCATTGAA 600

CCTGTGCAGT GGATGGAACC CGCCCTGCTG GGAGTGATGG ATGGGCAGCT TCTGTGCCCC 660

AAATGCAATG CCAAGTTGGG TTCTTTCAAT TGGTATGGTG AACAGTGCTC CTGTGGTAGA 720

TGGATAACCC CTGCTTTTCA AATCCACAAG AATAGAGTGG ATGAAATGAA AACGCTGCTG 780

GTTCTGGGAT CACAAACGAG AAAAATGTGA 810

Domain Profile

S: 57    nipvdDsdvtdllqyfdeaaefideakekggkvlvHCaaGvsRSatlvlaYLmkveglsl  116

          +p+ D+++tdll+++ ++++f+ +a+ +g++ lvHC+aGvsRS+++++a+Lmk+ +l++

Q: 8     FVPALDEPETDLLSHLGRCVAFLGRARAEGRAALVHCHAGVSRSVAVMTAFLMKTDQLTF  67

         599*********************************************************

S: 117   sdAieavkrkrpsiepnegfleQLlelekkl  147

         ++A+e++++ +p++++negf +QL +++ ++

Q: 68    EKAYENLQTIKPEAKMNEGFEWQLKLYQLMG  98

         **************************98775

Domain Sequence
(FASTA)

FVPALDEPET DLLSHLGRCV AFLGRARAEG RAALVHCHAG VSRSVAVMTA FLMKTDQLTF 60

EKAYENLQTI KPEAKMNEGF EWQLKLYQLM G 91

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Danio rerio"; ?>Dasypus novemcinctus"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0008138	; F:protein tyrosine/serine/threonine phosphatase activity
GO:0008270	; F:zinc ion binding
GO:0006470	; P:protein dephosphorylation

KEGG

InterPros

IPR000340	; Dual-sp_phosphatase_cat-dom.
IPR020422	; Dual-sp_phosphatase_subgr_cat.
IPR024950	; DUSP.
IPR016278	; DUSP12.
IPR000387	; Tyr/Dual-specificity_Pase.
IPR007087	; Znf_C2H2.

Pfam

PF00782

; DSPc; 1.

SMARTs

Prosites

PS50056	; TYR_PHOSPHATASE_2; 1.
PS50054	; TYR_PHOSPHATASE_DUAL; 1.
PS50157	; ZINC_FINGER_C2H2_2; 1.

Prints

Created Date

20-Feb-2013