EKS-MYL-00212

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-MYL-00212

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDKL	481.4	6.8E-145	4	286	283

Status

Unreviewed

Ensembl Protein

ENSMLUP00000011739

UniProt Accession

G1PLJ9;

Protein Name

Protein Synonyms/Alias

Gene Name

CDKL3

Gene Synonyms/Alias

CDKL3;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMLUG00000012902	ENSMLUP00000011739	ENSMLUT00000012906

Organism

Myotis lucifugus

Functional Description

Protein Length

594

Protein Sequence
(FASTA)

MDMYETLGKV GEGSYGTVMK CKHKDTGQIV AIKIFYETPE KSVNKIASRE IKFLKQFHHE 60

NLVNLIEVFR QKKKIHLVFE FIDHTVLDEL QHYCHGLESK RLRKYLFQII RAIEYLHNNN 120

IIHRDIKPEN ILVSQTGIIK LCDFGFARML AAPGDIYTDY VATRWYRAPE LVLKDTSYGK 180

PVDIWALGCM IIEMATGNPF LPSSSDLDLL HKIVLKVGNL TPHLQNFFSK SPIFAGVVLP 240

QVQHPKNARK KYPKLNGLLA DIVHACLQID PAERISSDDL LHHEYFTRDG FIEKFIPELR 300

AKLLQEAKVN SFIKSKENSK ENELMKDERK TMHTDTLLRT SVLGKEMEKE KKPKEIKTRV 360

IKVKGGKVDT LEPKKTEYES GHGQSDAIEN AHTVSQNVKS VINEPPNPAN PSTNSTGMKD 420

SPHAGGNMMM PPINLTSSNL MASNLNSNLS HSNSRLTERA KKRHTSSQSI GHVMTNNRQE 480

DTGPTQNQME KGVFSERTSQ SDQMASGNKR KLNFSRSDRK EFHFPKLPFI IQSNEMKRTE 540

EVKQIKVPKK ESKKTDSSKI PTLLNVDQNQ EKQEGGDGHC SEKNLKRSRF LGGS 594

Nucleotide Sequence
(FASTA)

ATGGATATGT ATGAAACTCT TGGAAAAGTG GGAGAAGGAA GTTATGGAAC AGTCATGAAG 60

TGTAAACATA AGGATACCGG GCAGATAGTG GCCATTAAGA TTTTTTATGA GACACCAGAA 120

AAATCTGTCA ACAAAATTGC ATCGAGAGAA ATAAAGTTTC TAAAGCAATT CCATCATGAA 180

AACCTGGTCA ATCTGATTGA AGTTTTTAGA CAGAAAAAGA AAATTCATTT GGTATTTGAA 240

TTTATTGACC ACACAGTATT AGATGAGTTA CAACATTATT GTCATGGACT AGAGAGTAAA 300

CGACTTAGAA AATACCTTTT CCAAATCATT CGAGCAATTG AATATCTTCA CAATAATAAT 360

ATCATTCATC GAGATATAAA ACCTGAGAAT ATTTTAGTAT CCCAGACAGG AATTATTAAA 420

CTCTGTGATT TCGGATTTGC ACGAATGCTA GCAGCTCCTG GGGATATTTA TACAGACTAT 480

GTGGCCACAC GCTGGTATAG AGCTCCAGAA TTAGTATTAA AAGATACCTC TTACGGAAAA 540

CCTGTGGATA TCTGGGCTTT GGGCTGTATG ATCATTGAGA TGGCCACTGG AAATCCCTTT 600

CTTCCTAGCA GCTCTGATTT GGATTTACTT CATAAAATTG TTTTAAAAGT AGGCAATTTG 660

ACACCTCACT TGCAGAATTT CTTTTCCAAG AGTCCTATTT TTGCAGGGGT GGTCCTTCCT 720

CAAGTTCAAC ACCCCAAGAA TGCAAGAAAA AAATACCCAA AGCTAAATGG ATTGTTAGCA 780

GATATAGTTC ATGCTTGTTT ACAAATTGAT CCTGCTGAGA GAATATCATC TGATGATCTT 840

TTGCATCATG AGTATTTTAC TAGAGATGGA TTTATTGAAA AATTCATACC AGAACTAAGA 900

GCTAAATTAC TACAAGAAGC AAAAGTCAAT TCATTCATAA AGTCAAAGGA GAATTCTAAA 960

GAAAATGAAC TTATGAAAGA TGAAAGAAAA ACAATGCATA CTGATACACT TCTACGAACT 1020

TCAGTTTTGG GAAAGGAAAT GGAAAAAGAG AAAAAGCCCA AGGAAATAAA AACCAGAGTT 1080

ATTAAAGTCA AAGGAGGAAA AGTAGATACC TTAGAACCAA AAAAGACAGA GTATGAAAGT 1140

GGACATGGTC AGTCAGATGC AATTGAAAAT GCTCATACTG TGTCTCAAAA TGTAAAATCT 1200

GTAATCAATG AACCACCAAA CCCTGCCAAT CCCAGCACTA ACTCTACTGG CATGAAAGAC 1260

AGTCCACATG CTGGAGGTAA TATGATGATG CCACCCATCA ACCTAACTAG CAGTAACCTG 1320

ATGGCTTCCA ATCTCAATTC AAATCTCTCC CACTCCAATT CAAGGTTAAC TGAAAGAGCA 1380

AAAAAGAGAC ATACTTCCTC ACAATCTATT GGACACGTTA TGACTAATAA CAGGCAAGAG 1440

GATACAGGTC CTACTCAAAA CCAAATGGAG AAAGGTGTAT TTAGTGAGCG GACAAGTCAA 1500

AGTGACCAAA TGGCAAGTGG AAATAAAAGG AAGCTGAATT TTTCCAGATC TGACAGGAAA 1560

GAATTCCATT TCCCAAAATT GCCTTTCATA ATACAATCAA ATGAGATGAA AAGAACGGAA 1620

GAAGTTAAAC AGATAAAAGT GCCGAAGAAG GAATCAAAGA AAACAGATTC ATCTAAAATA 1680

CCAACTTTAC TTAATGTGGA CCAAAATCAA GAAAAACAAG AGGGTGGAGA TGGCCATTGT 1740

TCGGAGAAGA ATTTGAAGAG GAGCAGATTT TTGGGGGGTA GC 1782

Domain Profile

S: 1     yeklgkvGeGsyGvvlkcrnkdtgqivaikkfleseddkevkkialreikllkqlkhenl  60

         ye+lgkvGeGsyG+v+kc++kdtgqivaik f+e+++ k+v+kia reik+lkq++henl

Q: 4     YETLGKVGEGSYGTVMKCKHKDTGQIVAIKIFYETPE-KSVNKIASREIKFLKQFHHENL  62

         9***********************************9.9*********************

S: 61    vnllevfrrkkklylvfeyvdktvldelerypnGveeelvkkilyqilkaiefchknnii  120

         vnl+evfr+kkk++lvfe++d+tvldel++y++G+e+++++k+l+qi++aie++h+nnii

Q: 63    VNLIEVFRQKKKIHLVFEFIDHTVLDELQHYCHGLESKRLRKYLFQIIRAIEYLHNNNII  122

         ************************************************************

S: 121   hrdikpenilisksgvvklcdfGfarllaapgdvytdyvatrwyrapellvgdtkyGksv  180

         hrdikpenil+s+ g++klcdfGfar+laapgd+ytdyvatrwyrapel+++dt+yGk+v

Q: 123   HRDIKPENILVSQTGIIKLCDFGFARMLAAPGDIYTDYVATRWYRAPELVLKDTSYGKPV  182

         ************************************************************

S: 181   dvwaiGcllaelltGeplfpgksdvdqlykirktlGeliprhqkifsknevfaGvklpev  240

         d+wa+Gc+++e++tG+p++p++sd+d l+ki+ ++G+l+p+ q+ fsk+++faGv+lp+v

Q: 183   DIWALGCMIIEMATGNPFLPSSSDLDLLHKIVLKVGNLTPHLQNFFSKSPIFAGVVLPQV  242

         ************************************************************

S: 241   edleslekkypklnevlldllkkclkldpaerlsceellkheyf  284

         +++++++kkypkln +l+d++++cl++dpaer+s+++ll+heyf

Q: 243   QHPKNARKKYPKLNGLLADIVHACLQIDPAERISSDDLLHHEYF  286

         *******************************************9

Domain Sequence
(FASTA)

YETLGKVGEG SYGTVMKCKH KDTGQIVAIK IFYETPEKSV NKIASREIKF LKQFHHENLV 60

NLIEVFRQKK KIHLVFEFID HTVLDELQHY CHGLESKRLR KYLFQIIRAI EYLHNNNIIH 120

RDIKPENILV SQTGIIKLCD FGFARMLAAP GDIYTDYVAT RWYRAPELVL KDTSYGKPVD 180

IWALGCMIIE MATGNPFLPS SSDLDLLHKI VLKVGNLTPH LQNFFSKSPI FAGVVLPQVQ 240

HPKNARKKYP KLNGLLADIV HACLQIDPAE RISSDDLLHH EYF 283

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Equus caballus"; ?>Felis catus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Nomascus leucogenys"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Vicugna pacos"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013