EKS-MYL-00170

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-MYL-00170

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/RSKb	497.8	6.0E-150	391	648	258

Status

Unreviewed

Ensembl Protein

ENSMLUP00000011814

UniProt Accession

G1PLR9;

Protein Name

Protein Synonyms/Alias

Gene Name

RPS6KA3

Gene Synonyms/Alias

RPS6KA3;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMLUG00000012980	ENSMLUP00000011814	ENSMLUT00000012986

Organism

Myotis lucifugus

Functional Description

Protein Length

709

Protein Sequence
(FASTA)

MGEEEINPQT EEGSIKEIAI THHVKEGHEK ADPSQFELLK VLGQGSFGKV FLVKKISGSD 60

ARQLYAMKVL KKATLKVRDR VRTKMERDIL VEVNHPFIVK LHYAFQTEGK LYLILDFLRG 120

GDLFTRLSKE VMFTEEDVKF YLAELALALD HLHSLGIIYR DLKPENILLD EEGHIKLTAD 180

FGLSKESIDH EKKAYSFCGT VEYMAPEVVN RRGHTQSADW WSFGVLMFEM LTGTLPFQGK 240

DRKETMTMIL KAKLGMPQFL SPEAQSLLRM LFKRNPANRL GAGPDGVEEI KRHLFFSTID 300

WNKLYRREIH PPFKPATGRP EDTFYFDPEF TAKTPKDSPG IPPSANAHQL FRGFSFVAIT 360

SDDESQAMQT VGVHSIVQQL HRNSIQFTDG YEVKEDIGVG SYSVCKRCIH KATNMEFAVK 420

IIDKSKRDPT EEIEILLRYG QHPNIITLKD VYDDGKYVYV VTELMKGGEL LDKILRQKFF 480

SEREASAVLF TITKTVEYLH AQGVVHRDLK PSNILYVDES GNPESIRICD FGFAKQLRAE 540

NGLLMTPCYT ANFVAPEVLK RQGYDAACDI WSLGVLLYTM LTGYTPFANG PDDTPEEILA 600

RIGSGKFSLS GGYWNSVSDT AKDLVSKMLH VDPHQRLTAA LVLRHPWIVH WDQLPQYQLN 660

RQDAPHLVKG AMAATYSALN RNQSPVLEPV GRSTLAQRRG IKKITSTAL 709

Nucleotide Sequence
(FASTA)

ATGGGAGAGG AAGAGATTAA TCCACAAACT GAAGAAGGCA GTATCAAAGA AATTGCAATC 60

ACACATCATG TAAAGGAAGG ACATGAAAAG GCAGATCCTT CCCAATTTGA ACTTTTAAAA 120

GTATTAGGGC AGGGATCATT TGGAAAAGTT TTCTTAGTCA AAAAAATCTC AGGCTCTGAT 180

GCTAGACAGC TTTATGCCAT GAAAGTATTG AAGAAGGCCA CTTTGAAAGT TCGAGACCGT 240

GTTCGGACAA AAATGGAGCG TGATATCTTG GTAGAAGTTA ATCATCCTTT TATTGTCAAG 300

TTGCATTATG CTTTTCAAAC TGAAGGGAAG TTGTATCTTA TTTTGGATTT TCTCAGGGGA 360

GGAGATTTGT TTACACGCTT ATCCAAAGAG GTGATGTTCA CAGAAGAAGA TGTCAAATTC 420

TACTTGGCTG AGCTTGCACT TGCTTTAGAC CATCTACATA GCCTGGGAAT AATCTATAGA 480

GACTTAAAAC CAGAAAACAT ACTTCTTGAT GAAGAAGGTC ACATCAAATT AACAGCAGAT 540

TTTGGCCTAA GTAAAGAGTC TATTGACCAT GAGAAGAAAG CATATTCTTT TTGTGGAACT 600

GTGGAATATA TGGCTCCAGA AGTAGTTAAT CGTCGAGGTC ATACTCAAAG TGCGGACTGG 660

TGGTCTTTTG GTGTGTTAAT GTTTGAGATG CTCACTGGTA CACTACCCTT CCAAGGAAAA 720

GATCGAAAAG AAACAATGAC TATGATCCTT AAAGCTAAAC TTGGGATGCC ACAGTTTTTG 780

AGTCCTGAAG CCCAGAGTCT TTTACGAATG CTTTTCAAAC GAAATCCTGC AAACAGATTA 840

GGTGCAGGAC CAGATGGAGT GGAAGAAATT AAAAGACATT TATTTTTCTC AACAATAGAT 900

TGGAATAAAC TATACAGAAG AGAAATTCAT CCACCTTTTA AACCTGCAAC TGGCAGGCCT 960

GAAGATACAT TCTATTTTGA TCCTGAGTTT ACTGCAAAAA CTCCCAAAGA TTCACCTGGC 1020

ATTCCACCTA GTGCTAATGC ACATCAGCTT TTTCGGGGGT TTAGTTTTGT TGCTATTACC 1080

TCAGATGACG AAAGCCAAGC TATGCAGACA GTTGGTGTGC ATTCAATTGT TCAGCAGTTG 1140

CACAGGAACA GTATTCAGTT TACTGATGGA TATGAAGTGA AAGAAGATAT TGGAGTTGGC 1200

TCCTACTCTG TTTGTAAGAG ATGTATACAT AAAGCCACAA ACATGGAGTT TGCAGTAAAG 1260

ATTATTGATA AAAGCAAGAG AGACCCAACA GAGGAAATTG AAATTCTTCT TCGTTATGGA 1320

CAGCATCCAA ACATTATTAC TCTAAAGGAT GTATATGATG ATGGAAAATA TGTGTACGTG 1380

GTGACAGAAC TTATGAAAGG GGGTGAATTG CTGGATAAAA TTCTTAGACA GAAATTTTTC 1440

TCTGAACGAG AGGCCAGCGC TGTCCTGTTT ACTATAACCA AAACTGTTGA ATATCTTCAT 1500

GCTCAAGGGG TGGTTCACAG AGACTTAAAA CCAAGCAACA TTCTTTATGT GGACGAATCT 1560

GGCAATCCAG AATCTATTCG AATTTGTGAT TTTGGCTTTG CCAAACAGCT AAGAGCAGAA 1620

AACGGTCTTC TCATGACACC TTGTTATACT GCAAATTTTG TTGCACCAGA GGTTTTGAAA 1680

CGACAAGGCT ATGATGCTGC TTGTGATATA TGGAGTCTTG GTGTCCTCCT CTATACAATG 1740

CTTACTGGTT ACACTCCATT TGCAAATGGC CCTGATGATA CACCAGAGGA AATACTGGCA 1800

CGCATCGGCA GTGGAAAATT CTCACTCAGT GGTGGTTACT GGAATTCTGT TTCAGATACA 1860

GCAAAGGACC TGGTGTCAAA GATGCTTCAT GTGGACCCTC ATCAGAGATT GACTGCTGCC 1920

CTTGTGCTCA GACACCCTTG GATAGTCCAC TGGGACCAAC TGCCACAATA CCAACTAAAC 1980

AGACAGGACG CACCACATCT GGTCAAGGGT GCCATGGCAG CTACATATTC TGCTTTAAAC 2040

CGTAATCAGT CACCAGTTTT GGAACCAGTA GGCCGCTCTA CTCTTGCTCA GCGAAGAGGT 2100

ATTAAAAAAA TCACCTCCAC AGCCCTGTGA 2130

Domain Profile

S: 1     yevkedlGvGsysvckrcvhkatnqefavkiidkskrdtseeieillryeqhpnivtlkd  60

         yevked+GvGsysvckrc+hkatn+efavkiidkskrd++eeieillry+qhpni+tlkd

Q: 391   YEVKEDIGVGSYSVCKRCIHKATNMEFAVKIIDKSKRDPTEEIEILLRYGQHPNIITLKD  450

         789*********************************************************

S: 61    vyddgkyvylvlellkGGelldrikkkkffsereasailrtlvkaveylheqGvvhrdlk  120

         vyddgkyvy+v+el+kGGelld+i+++kffsereasa+l+t++k+veylh+qGvvhrdlk

Q: 451   VYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLHAQGVVHRDLK  510

         ************************************************************

S: 121   penilyvdesdnaesikiidfGfaklkraengllktpcytlnfvapevlkrqGydeacdl  180

         p+nilyvdes+n+esi+i+dfGfak++raengll+tpcyt+nfvapevlkrqGyd+acd+

Q: 511   PSNILYVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGYDAACDI  570

         ************************************************************

S: 181   wslGvllytmlaGyvpfangpedtaeeilakikeGkfslsGeawdsvseeakdlvskllt  240

         wslGvllytml+Gy+pfangp+dt+eeila+i++GkfslsG++w+svs++akdlvsk+l+

Q: 571   WSLGVLLYTMLTGYTPFANGPDDTPEEILARIGSGKFSLSGGYWNSVSDTAKDLVSKMLH  630

         ************************************************************

S: 241   vdpakrlkleqllkhswl  258

         vdp++rl+++ +l+h+w+

Q: 631   VDPHQRLTAALVLRHPWI  648

         *****************8

Domain Sequence
(FASTA)

YEVKEDIGVG SYSVCKRCIH KATNMEFAVK IIDKSKRDPT EEIEILLRYG QHPNIITLKD 60

VYDDGKYVYV VTELMKGGEL LDKILRQKFF SEREASAVLF TITKTVEYLH AQGVVHRDLK 120

PSNILYVDES GNPESIRICD FGFAKQLRAE NGLLMTPCYT ANFVAPEVLK RQGYDAACDI 180

WSLGVLLYTM LTGYTPFANG PDDTPEEILA RIGSGKFSLS GGYWNSVSDT AKDLVSKMLH 240

VDPHQRLTAA LVLRHPWI 258

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0000287	; F:magnesium ion binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0007243	; P:intracellular protein kinase cascade

KEGG

InterPros

IPR000961	; AGC-kinase_C.
IPR011009	; Kinase-like_dom.
IPR017892	; Pkinase_C.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR016239	; Ribosomal_S6_kinase_II.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069	; Pkinase; 2.
PF00433	; Pkinase_C; 1.

SMARTs

SM00133	; S_TK_X; 1.
SM00220	; S_TKc; 2.

Prosites

PS51285	; AGC_KINASE_CTER; 1.
PS00107	; PROTEIN_KINASE_ATP; 2.
PS50011	; PROTEIN_KINASE_DOM; 2.
PS00108	; PROTEIN_KINASE_ST; 2.

Prints

Created Date

20-Feb-2013