EKS-MYL-00066

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-MYL-00066

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDK	368.7	1.8E-110	19	316	298

Status

Unreviewed

Ensembl Protein

ENSMLUP00000012271

UniProt Accession

G1PMX9;

Protein Name

Protein Synonyms/Alias

Gene Name

CDK9

Gene Synonyms/Alias

CDK9;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMLUG00000013482	ENSMLUP00000012271	ENSMLUT00000013486

Organism

Myotis lucifugus

Functional Description

Protein Length

373

Protein Sequence
(FASTA)

MAKQYDSVEC PFCDEVTKYE KLTKIGQGTF GEVFKAKHRL TGQKVALKKV LMENEKEGFP 60

ITALREIKIL QLLKHENVVN LIELCLVSSA SPYNRCKGSI YLVFDFCEHD LAGLLSNVLV 120

KFTLSEIKKV MQMLLNGLYY IHRNKILHRD MKAANVLITR DGVLKLADFG LARAFSLAKN 180

SQPNRYTNRV VTLWYRPPEL LLGERDYGPP IDLWGAGCIM AEMWTRSPIM QGNTEQHQLA 240

LISQLCGSIT PEVWPNVDKY ELFEKLELVK GQKRKVKDRL KAYVRDPYAL DLIDKLLVLD 300

PAQRIDSDDA LNHDFFWSDP MPSDLKGMLS THLTSMFEYL APPRRKGSQI TQPSTNQSRN 360

PTNTNQTEFE RVF 373

Nucleotide Sequence
(FASTA)

ATGGCAAAGC AATACGACTC AGTGGAGTGC CCCTTTTGTG ATGAGGTGAC CAAATATGAG 60

AAGCTCACTA AGATCGGCCA AGGCACTTTT GGGGAGGTGT TTAAGGCAAA GCATCGCCTG 120

ACCGGCCAAA AGGTGGCTCT GAAGAAAGTC CTGATGGAGA ACGAGAAGGA GGGGTTCCCC 180

ATTACGGCCT TGCGGGAAAT CAAGATCCTC CAGCTTCTAA AACATGAGAA TGTGGTCAAC 240

TTGATTGAGC TTTGCTTAGT CTCCTCAGCT TCCCCCTATA ACCGCTGCAA AGGCAGTATA 300

TACCTGGTGT TCGACTTCTG CGAGCATGAC CTTGCTGGGC TGCTGAGCAA CGTGTTAGTC 360

AAGTTCACGC TGTCTGAGAT CAAGAAGGTC ATGCAGATGC TGCTCAATGG CCTCTACTAC 420

ATCCATAGGA ACAAGATCCT GCACAGGGAC ATGAAGGCAG CTAACGTGCT CATCACCCGA 480

GATGGGGTGC TGAAACTGGC AGACTTTGGG CTGGCCAGGG CCTTCAGTCT GGCCAAGAAC 540

AGCCAGCCCA ACCGCTATAC CAACCGTGTG GTGACACTCT GGTACCGGCC CCCGGAGCTG 600

TTGCTCGGGG AGCGCGACTA CGGTCCCCCC ATTGACCTGT GGGGTGCTGG GTGCATCATG 660

GCGGAGATGT GGACCCGCAG CCCTATCATG CAGGGCAACA CGGAGCAGCA CCAGCTTGCC 720

CTCATCAGCC AGCTCTGTGG CTCCATCACC CCTGAGGTGT GGCCAAATGT GGACAAGTAC 780

GAGCTGTTCG AGAAACTGGA GCTAGTGAAG GGCCAGAAGC GGAAGGTGAA GGATCGGCTG 840

AAGGCCTATG TGCGTGACCC CTACGCACTG GACCTCATCG ACAAGTTGCT GGTGCTGGAC 900

CCGGCGCAGC GCATCGACAG CGACGATGCC CTCAACCATG ACTTCTTCTG GTCTGACCCC 960

ATGCCCTCGG ACCTCAAGGG CATGCTCTCC ACCCACCTGA CATCCATGTT CGAGTACCTG 1020

GCGCCACCAC GCCGGAAGGG CAGCCAGATC ACCCAGCCTT CCACTAACCA GAGCCGCAAC 1080

CCCACCAATA CCAACCAGAC GGAGTTCGAG CGTGTCTTCT GA 1122

Domain Profile

S: 1     yeklekigeGtygkvykakdketgevvAlKkirlekekegvpitalrEisllkelkhkni  60

         yekl+kig+Gt+g+v+kak++ tg++vAlKk+ +e+ekeg+pitalrEi++l+ lkh+n+

Q: 19    YEKLTKIGQGTFGEVFKAKHRLTGQKVALKKVLMENEKEGFPITALREIKILQLLKHENV  78

         99**********************************************************

S: 61    vkLlevva........kdkkklyLvfefleqdLkkllkkkkkkklsleevkslllqlleg  112

         v+L+e++         + k ++yLvf+f+e+dL+ ll++    k++l+e+k+++++ll+g

Q: 79    VNLIELCLvssaspynRCKGSIYLVFDFCEHDLAGLLSNVLV-KFTLSEIKKVMQMLLNG  137

         *******99*****98889**********************9.*****************

S: 113   laylHsnkilHRDlKpqNlLiskegklklaDfGlaraf....ssplktytkevvTlwYra  168

         l y+H+nkilHRD+K++N+Li+++g+lklaDfGlaraf    +s+ ++yt++vvTlwYr+

Q: 138   LYYIHRNKILHRDMKAANVLITRDGVLKLADFGLARAFslakNSQPNRYTNRVVTLWYRP  197

         **************************************7776555557************

S: 169   PelLlgakeYstavDiWsvgcilaelltrkplfqgkseidqlerifkllgtpsekvwpev  228

         PelLlg+++Y+  +D+W++gci+ae++tr+p++qg++e++ql  i++l+g+++ +vwp+v

Q: 198   PELLLGERDYGPPIDLWGAGCIMAEMWTRSPIMQGNTEQHQLALISQLCGSITPEVWPNV  257

         ************************************************************

S: 229   sklpeyk.ksfpkkkkkklkekvkklkek..aldllekllaldpkkRisakealqhkyf  284

          k++ ++  ++ k +k+k+k+++k++ ++  aldl++kll ldp++Ri++++al+h++f

Q: 258   DKYELFEkLELVKGQKRKVKDRLKAYVRDpyALDLIDKLLVLDPAQRIDSDDALNHDFF  316

         *******7799999999999999887755469*************************98

Domain Sequence
(FASTA)

YEKLTKIGQG TFGEVFKAKH RLTGQKVALK KVLMENEKEG FPITALREIK ILQLLKHENV 60

VNLIELCLVS SASPYNRCKG SIYLVFDFCE HDLAGLLSNV LVKFTLSEIK KVMQMLLNGL 120

YYIHRNKILH RDMKAANVLI TRDGVLKLAD FGLARAFSLA KNSQPNRYTN RVVTLWYRPP 180

ELLLGERDYG PPIDLWGAGC IMAEMWTRSP IMQGNTEQHQ LALISQLCGS ITPEVWPNVD 240

KYELFEKLEL VKGQKRKVKD RLKAYVRDPY ALDLIDKLLV LDPAQRIDSD DALNHDFF 298

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013