EKS-MYL-00426

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-MYL-00426

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/ULK	360.6	5.5E-108	14	270	257

Status

Unreviewed

Ensembl Protein

ENSMLUP00000012434

UniProt Accession

G1PNC1;

Protein Name

Protein Synonyms/Alias

Gene Name

ULK3

Gene Synonyms/Alias

ULK3;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMLUG00000013660	ENSMLUP00000012434	ENSMLUT00000013661

Organism

Myotis lucifugus

Functional Description

Protein Length

472

Protein Sequence
(FASTA)

MAGSSWGPPR LDGFILTERL GSGTYATVYK AYAKKDTREV VAIKCVAKKS LNKASVENLL 60

TEIEILKGIR HPHIVQLKDF QWDSDNIYLI MEFCAGGDLS RFIHTRRILP EKVARVFMQQ 120

IASALQFLHA RNISHLDLKP QNILLSSLEK PHLKLADFGF SQHMSPWDEK HVLRGSPLYM 180

APEMVCQRQY DARVDLWSVG VILYEALFGQ PPFASRSFTE LEEKIRSNRV IELPLRPQLS 240

PDCQDLLRRL LERDPGRRIS FQDFFAHPWV DLDHMPSEES LARATILVVQ AVKKDQEGDA 300

AAALSLYCKA LDFFVPALHY EVDAQRKEAI KAKVRQYVSR AEELKAIVSS SNQALLRQGA 360

SAQDLLREMA RDKPRLLAAL EVASAAVAKE EEAGGEQDAL DLYQHSLGEL LLLLAGEPPG 420

RRRELLHTEV QNLMARAEYL KEQVKMRESR WEAETLDKEG LLESVRTSCT LQ 472

Nucleotide Sequence
(FASTA)

ATGGCGGGGT CCAGCTGGGG TCCCCCGCGG CTGGATGGCT TCATTCTCAC CGAGCGCCTG 60

GGCAGTGGCA CGTACGCCAC GGTGTACAAG GCCTACGCCA AGAAGGACAC TCGAGAGGTG 120

GTAGCCATAA AATGTGTGGC CAAGAAGAGC CTGAACAAGG CATCCGTGGA AAACCTCCTG 180

ACAGAGATTG AAATCCTCAA GGGCATTCGA CACCCCCACA TCGTCCAGCT GAAAGACTTC 240

CAGTGGGACA GTGACAACAT CTACCTCATC ATGGAGTTCT GTGCAGGAGG TGACCTGTCT 300

CGCTTCATCC ATACCCGCCG GATTCTGCCT GAGAAGGTGG CTCGTGTCTT CATGCAGCAG 360

ATAGCTAGTG CCCTGCAGTT TCTGCACGCA CGAAACATAT CTCACCTGGA TCTGAAGCCA 420

CAGAACATTC TGCTGAGCTC CTTGGAGAAG CCCCACCTTA AACTGGCAGA CTTCGGCTTC 480

TCACAGCACA TGTCCCCGTG GGACGAGAAG CATGTGCTCC GCGGCTCCCC TCTCTACATG 540

GCCCCCGAGA TGGTGTGTCA GCGGCAGTAC GATGCCCGTG TGGACCTCTG GTCCGTGGGG 600

GTCATTCTGT ATGAAGCCCT CTTCGGGCAG CCCCCCTTTG CCTCCAGGTC GTTCACAGAG 660

CTGGAAGAGA AGATCCGGAG TAATCGGGTT ATCGAGCTTC CCCTTCGGCC CCAGCTCTCC 720

CCAGACTGCC AGGACCTGCT GCGGCGGCTC CTAGAGCGGG ACCCTGGTCG TCGCATCTCC 780

TTCCAGGACT TCTTTGCCCA CCCCTGGGTG GACCTGGACC ACATGCCCAG TGAGGAGAGC 840

CTGGCACGAG CAACCATCCT GGTGGTGCAG GCTGTGAAGA AGGACCAGGA GGGGGATGCT 900

GCGGCTGCCT TATCGCTCTA CTGCAAGGCT CTGGACTTCT TTGTGCCTGC CCTGCACTAC 960

GAAGTGGATG CACAGCGGAA GGAGGCAATT AAGGCAAAGG TGCGACAGTA CGTGTCCCGG 1020

GCTGAGGAGC TCAAGGCCAT TGTGTCCTCC TCCAATCAGG CCCTGCTGAG ACAGGGGGCC 1080

TCTGCCCAAG ACCTGCTCAG AGAGATGGCT CGGGACAAGC CACGCCTCCT GGCTGCTCTG 1140

GAAGTGGCTT CAGCTGCTGT GGCCAAGGAG GAGGAAGCTG GTGGGGAGCA GGACGCCCTG 1200

GACCTGTACC AGCACAGCCT GGGGGAGCTG CTGCTGCTGC TGGCAGGGGA GCCCCCAGGC 1260

CGGAGGCGGG AACTGCTTCA CACTGAGGTT CAGAACCTCA TGGCTCGAGC TGAATACCTG 1320

AAAGAGCAAG TCAAGATGAG GGAGTCTCGC TGGGAAGCCG AGACCTTGGA CAAGGAGGGG 1380

CTGTTGGAGT CTGTCCGGAC CTCTTGCACC CTGCAGTGA 1419

Domain Profile

S: 1     ysleeeiGkGsfavvykgrlrkktsqvvAikvvekkkl.kkslenlekeikilkelkhen  59

         ++l+e++G+G++a+vyk++++k+t++vvAik+v+kk+l k+s+enl +ei+ilk ++h++

Q: 14    FILTERLGSGTYATVYKAYAKKDTREVVAIKCVAKKSLnKASVENLLTEIEILKGIRHPH  73

         7899**********************************999*******************

S: 60    ivalldveetskevylvmeycaggdLakllkqkkeLsedtvreflqqlasalkaLhskki  119

         iv+l+d++++s+++yl+me+caggdL++++++++ L+e+++r+f+qq+asal++Lh+++i

Q: 74    IVQLKDFQWDSDNIYLIMEFCAGGDLSRFIHTRRILPEKVARVFMQQIASALQFLHARNI  133

         ************************************************************

S: 120   vhrDlkPqniLlsyadakkelkkvtlkladFglarvlkeesmaatlkGsplYmaPEvvke  179

         +h DlkPqniLls      +l+k +lkladFg++++++ +++++ l+GsplYmaPE+v++

Q: 134   SHLDLKPQNILLS------SLEKPHLKLADFGFSQHMSPWDEKHVLRGSPLYMAPEMVCQ  187

         *************......89***************************************

S: 180   qqydakaDlWSiGtilyellvGkpPfaaesiseLvekiekndvleppipkeisselkdll  239

         +qyda++DlWS+G+ilye+l+G+pPfa++s++eL+eki++n+v+e+p++ ++s++++dll

Q: 188   RQYDARVDLWSVGVILYEALFGQPPFASRSFTELEEKIRSNRVIELPLRPQLSPDCQDLL  247

         ************************************************************

S: 240   qsLLqrdpkkRisfeelfahpfl  262

         ++LL+rdp +Risf+++fahp++

Q: 248   RRLLERDPGRRISFQDFFAHPWV  270

         *********************96

Domain Sequence
(FASTA)

FILTERLGSG TYATVYKAYA KKDTREVVAI KCVAKKSLNK ASVENLLTEI EILKGIRHPH 60

IVQLKDFQWD SDNIYLIMEF CAGGDLSRFI HTRRILPEKV ARVFMQQIAS ALQFLHARNI 120

SHLDLKPQNI LLSSLEKPHL KLADFGFSQH MSPWDEKHVL RGSPLYMAPE MVCQRQYDAR 180

VDLWSVGVIL YEALFGQPPF ASRSFTELEE KIRSNRVIEL PLRPQLSPDC QDLLRRLLER 240

DPGRRISFQD FFAHPWV 257

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dasypus novemcinctus"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR007330	; MIT.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF04212	; MIT; 2.
PF00069	; Pkinase; 1.

SMARTs

SM00745	; MIT; 2.
SM00220	; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013