EKS-MYL-00371

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-MYL-00371

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
TK/Src	384.3	2.4E-115	191	440	250

Status

Unreviewed

Ensembl Protein

ENSMLUP00000013262

UniProt Accession

G1PQC0;

Protein Name

Protein Synonyms/Alias

Gene Name

PTK6

Gene Synonyms/Alias

PTK6;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMLUG00000014570	ENSMLUP00000013262	ENSMLUT00000014576

Organism

Myotis lucifugus

Functional Description

Protein Length

450

Protein Sequence
(FASTA)

MVSRGRARLG PQYVGLWDFK ARTNEELSFR AGDLFHVARK EEEWWWATLL DAEGGALAEG 60

YVPHNYLAER ETVESEPWFF GCISRLEALH RLQADGTEPG AFLIRVSEKP GADYVLSVRD 120

RQAVRHYRIW RCAGRLHLSE AVSFPSLAQL VGHHQAHSLS KGLRLTVPCW KHEREPLPLC 180

ADWERPREEF TLCRKLGAGY FGEVFEGLWK GQVRVAIKVI ARDDLLHQHT FQSEIQAMKK 240

LRHKHILALY AVASVGDPVY IITELMAKGS LLELLRESDE KALPVLELVD IASQVAEGMC 300

YLESQNYIHR DLAARNILVG ENNICKVGDF GLARLIKEDI YLSHDRNIPY KWTAPEALSR 360

GHYSIKSDVW SFGVLLHEIF SRGQTPYPGM SNHEAFMRVD SGYRMPCPPE CPPSAHRLML 420

ACWHRSPEQR PCFRALREKL CSFTSYENPI 450

Nucleotide Sequence
(FASTA)

ATGGTGTCCC GGGGCCGAGC CCGCCTGGGC CCCCAGTATG TGGGCCTCTG GGACTTCAAG 60

GCCCGGACAA ACGAGGAGCT AAGCTTCCGG GCAGGCGACC TCTTCCACGT GGCCCGGAAG 120

GAGGAGGAGT GGTGGTGGGC CACACTGCTG GACGCAGAGG GCGGGGCCCT GGCTGAAGGC 180

TACGTGCCCC ACAACTACCT GGCCGAGAGG GAGACTGTGG AGTCCGAGCC GTGGTTCTTC 240

GGCTGCATCT CCCGCTTGGA AGCCTTGCAC CGACTGCAGG CAGATGGCAC GGAGCCAGGG 300

GCCTTCCTGA TCAGGGTCAG CGAGAAGCCG GGCGCCGACT ATGTCCTCTC AGTGCGGGAC 360

AGGCAGGCCG TGCGGCACTA CAGGATCTGG AGGTGTGCTG GCCGGCTGCA CCTCAGCGAA 420

GCTGTGTCCT TCCCCAGCCT GGCCCAGCTC GTGGGCCACC ACCAGGCACA CAGCCTGTCC 480

AAAGGCCTGC GGCTGACTGT GCCCTGCTGG AAGCACGAGC GGGAGCCCCT GCCCCTCTGT 540

GCCGACTGGG AGCGGCCCCG GGAGGAGTTC ACGCTCTGCA GGAAGCTGGG GGCCGGCTAC 600

TTCGGGGAGG TCTTCGAGGG GCTCTGGAAA GGCCAGGTCC GCGTGGCCAT TAAGGTGATT 660

GCCCGAGACG ACCTCCTGCA CCAGCACACG TTCCAGTCGG AGATCCAGGC CATGAAGAAG 720

CTTCGGCACA AGCACATCCT GGCGCTGTAT GCGGTGGCGT CCGTGGGGGA CCCCGTGTAC 780

ATCATCACAG AGCTCATGGC GAAGGGGAGC CTGCTGGAGC TCCTGCGGGA GTCTGATGAG 840

AAAGCCCTGC CTGTCTTGGA GCTGGTGGAC ATTGCCTCCC AGGTGGCTGA GGGCATGTGC 900

TACCTGGAGT CGCAGAATTA CATCCACCGG GACCTGGCTG CCAGGAACAT CCTCGTGGGA 960

GAGAACAACA TTTGCAAAGT GGGGGATTTC GGGCTGGCCA GGCTCATCAA GGAGGACATC 1020

TACCTTTCCC ACGACCGCAA CATCCCCTAC AAGTGGACCG CCCCCGAGGC GCTCTCCCGA 1080

GGGCACTACT CCATCAAGTC CGACGTCTGG TCCTTCGGGG TCCTCCTCCA TGAGATTTTC 1140

AGCAGGGGCC AGACGCCCTA TCCAGGCATG TCCAACCACG AGGCCTTCAT GAGAGTGGAC 1200

TCTGGCTACC GCATGCCCTG CCCCCCCGAG TGCCCGCCCA GTGCCCACAG GCTGATGCTC 1260

GCATGCTGGC ACCGAAGCCC TGAGCAGAGG CCCTGCTTCC GAGCCCTGCG GGAGAAGCTC 1320

TGCAGCTTCA CCAGCTACGA GAACCCAATC TGA 1353

Domain Profile

S: 2     klvkklGeGqfGevwlgkwkgsvkvavktlkegt.lspeafleeaqilkklrheklvkly  60

         +l++klG+G+fGev++g+wkg+v+va+k++ +++ l++++f++e+q++kklrh+++++ly

Q: 191   TLCRKLGAGYFGEVFEGLWKGQVRVAIKVIARDDlLHQHTFQSEIQAMKKLRHKHILALY  250

         799***************************9998799***********************

S: 61    avvseeePiyivtelmakGslldflkeeegkklklpklvdlaaqvaeGmayleeknlihr  120

         av+s ++P+yi+telmakGsll++l+e+++k+l++ +lvd+a+qvaeGm+yle++n+ihr

Q: 251   AVASVGDPVYIITELMAKGSLLELLRESDEKALPVLELVDIASQVAEGMCYLESQNYIHR  310

         ************************************************************

S: 121   dlaarnvlvgeslvvkvadfGlarlieddeytakegaklPikWtaPeaiklgkftiksdv  180

         dlaarn+lvge++++kv+dfGlarli++d+y +++  ++P+kWtaPea++ g+++iksdv

Q: 311   DLAARNILVGENNICKVGDFGLARLIKEDIYLSHD-RNIPYKWTAPEALSRGHYSIKSDV  369

         *******************************9876.99**********************

S: 181   WsfGillteivtkGkvPypGmtneevleqvergyrlprpeecpeelyelllecwkkdpee  240

         WsfG+ll+ei+++G++PypGm+n+e++ +v+ gyr+p+p ecp + ++l+l cw+++pe+

Q: 370   WSFGVLLHEIFSRGQTPYPGMSNHEAFMRVDSGYRMPCPPECPPSAHRLMLACWHRSPEQ  429

         ************************************************************

S: 241   rPtfetlqevl  251

         rP+f +l+e+l

Q: 430   RPCFRALREKL  440

         *******9876

Domain Sequence
(FASTA)

TLCRKLGAGY FGEVFEGLWK GQVRVAIKVI ARDDLLHQHT FQSEIQAMKK LRHKHILALY 60

AVASVGDPVY IITELMAKGS LLELLRESDE KALPVLELVD IASQVAEGMC YLESQNYIHR 120

DLAARNILVG ENNICKVGDF GLARLIKEDI YLSHDRNIPY KWTAPEALSR GHYSIKSDVW 180

SFGVLLHEIF SRGQTPYPGM SNHEAFMRVD SGYRMPCPPE CPPSAHRLML ACWHRSPEQR 240

PCFRALREKL 250

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; SH3 domain; Transferase; Tyrosine-protein kinase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Nomascus leucogenys"; ?>Ornithorhynchus anatinus"; ?>Oryzias latipes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004713	; F:protein tyrosine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR001245	; Ser-Thr/Tyr_kinase_cat_dom.
IPR000980	; SH2.
IPR001452	; SH3_domain.
IPR008266	; Tyr_kinase_AS.
IPR020635	; Tyr_kinase_cat_dom.

Pfam

PF07714	; Pkinase_Tyr; 1.
PF00017	; SH2; 1.
PF00018	; SH3_1; 1.

SMARTs

SM00252	; SH2; 1.
SM00326	; SH3; 1.
SM00219	; TyrKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00109	; PROTEIN_KINASE_TYR; 1.
PS50001	; SH2; 1.
PS50002	; SH3; 1.

Prints

PR00401	; SH2DOMAIN.
PR00452	; SH3DOMAIN.
PR00109	; TYRKINASE.

Created Date

20-Feb-2013