EKS-MYL-00060

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-MYL-00060

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDK	394.8	2.1E-118	4	288	285

Status

Unreviewed

Ensembl Protein

ENSMLUP00000013385

UniProt Accession

G1PQL9;

Protein Name

Protein Synonyms/Alias

Gene Name

CDK5

Gene Synonyms/Alias

CDK5;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMLUG00000014708	ENSMLUP00000013385	ENSMLUT00000014712

Organism

Myotis lucifugus

Functional Description

Protein Length

294

Protein Sequence
(FASTA)

MQKYEKLEKI GEGTYGTVFK AKNRETHEIV ALKRVRLDDD DEGVPSSALR EICLLKELKH 60

KNIVRLHDVL HSDKKLTLVF EFCDQDLKKY FDSCNGDLDP EIVKSFLFQL LKGLGFCHSR 120

NVLHRDLKPQ NLLINRNGEL KLADFGLARA FGIPVRCYSA EVVTLWYRPP DVLFGAKLYS 180

TSIDMWSAGC IFAELANAGR PLFPGNDVDD QLKRIFRDTL LGTPTEEQWP AMTKLPDYKP 240

YPMYPATTSL VNVVPKLNAT GRDLLQNLLK CNPIQRISAE EALQHPYFSD FCPP 294

Nucleotide Sequence
(FASTA)

ATGCAGAAAT ACGAGAAACT GGAGAAGATT GGGGAAGGCA CCTACGGAAC AGTGTTCAAG 60

GCCAAAAACC GGGAGACTCA TGAGATCGTG GCCCTGAAAC GGGTGAGGCT GGATGACGAT 120

GATGAGGGAG TGCCGAGTTC TGCCCTTCGG GAAATCTGCC TACTCAAAGA GCTGAAGCAC 180

AAGAACATTG TCAGGCTTCA TGATGTCCTG CATAGCGACA AGAAGTTGAC TTTGGTTTTT 240

GAGTTCTGTG ACCAGGACCT TAAGAAATAT TTTGACAGCT GCAATGGTGA TCTAGATCCT 300

GAAATTGTGA AGTCATTCCT CTTCCAGCTG CTAAAAGGCC TGGGATTTTG TCATAGCCGA 360

AACGTGCTGC ACAGGGACCT GAAGCCTCAG AATCTGCTCA TAAACAGGAA TGGGGAGCTG 420

AAATTGGCTG ATTTCGGGTT GGCTCGAGCC TTTGGGATCC CTGTTCGCTG TTACTCCGCT 480

GAGGTGGTCA CGCTGTGGTA CCGCCCACCG GATGTCCTCT TTGGGGCCAA GCTGTACTCC 540

ACGTCCATTG ACATGTGGTC AGCCGGCTGC ATTTTTGCAG AGCTGGCCAA TGCAGGGAGG 600

CCTCTCTTCC CCGGCAACGA TGTAGATGAC CAGTTGAAGA GGATCTTCCG AGACACACTG 660

CTGGGGACAC CGACTGAGGA GCAATGGCCC GCCATGACCA AGCTGCCGGA CTATAAGCCC 720

TACCCGATGT ACCCGGCCAC AACATCCCTG GTGAACGTCG TACCCAAGCT CAATGCCACA 780

GGCAGGGACC TGCTGCAGAA CCTCCTGAAG TGCAACCCCA TCCAGCGCAT CTCGGCAGAG 840

GAGGCTCTGC AGCACCCCTA CTTCTCCGAC TTCTGCCCCC CCTAG 885

Domain Profile

S: 1     yeklekigeGtygkvykakdketgevvAlKkirlekekegvpitalrEisllkelkhkni  60

         yeklekigeGtyg+v+kak++et+e+vAlK++rl++++egvp++alrEi llkelkhkni

Q: 4     YEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKHKNI  63

         99**********************************************************

S: 61    vkLlevvakdkkklyLvfefleqdLkkllkkkkkkklsleevkslllqlleglaylHsnk  120

         v+L++v++ ++kkl+Lvfef++qdLkk++++++  +l++e vks+l+qll+gl ++Hs++

Q: 64    VRLHDVLH-SDKKLTLVFEFCDQDLKKYFDSCNG-DLDPEIVKSFLFQLLKGLGFCHSRN  121

         ********.99***********************.*************************

S: 121   ilHRDlKpqNlLiskegklklaDfGlarafssplktytkevvTlwYraPelLlgakeYst  180

         +lHRDlKpqNlLi+++g+lklaDfGlaraf+ p++ y+ evvTlwYr+P++L+gak Yst

Q: 122   VLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKLYST  181

         ************************************************************

S: 181   avDiWsvgcilaellt.rkplfqgkseidqlerifk..llgtpsekvwpevsklpeykks  237

         ++D+Ws+gci+ael++  +plf+g++  dql+rif+  llgtp+e++wp ++klp+yk

Q: 182   SIDMWSAGCIFAELANaGRPLFPGNDVDDQLKRIFRdtLLGTPTEEQWPAMTKLPDYK-P  240

         **************97369****************75589******************.5

S: 238   fpkkkkk.klkekvkklkekaldllekllaldpkkRisakealqhkyf  284

         +p ++++ +l ++v+kl+ +++dll++ll+++p +Risa+ealqh+yf

Q: 241   YPMYPATtSLVNVVPKLNATGRDLLQNLLKCNPIQRISAEEALQHPYF  288

         555555559**************************************9

Domain Sequence
(FASTA)

YEKLEKIGEG TYGTVFKAKN RETHEIVALK RVRLDDDDEG VPSSALREIC LLKELKHKNI 60

VRLHDVLHSD KKLTLVFEFC DQDLKKYFDS CNGDLDPEIV KSFLFQLLKG LGFCHSRNVL 120

HRDLKPQNLL INRNGELKLA DFGLARAFGI PVRCYSAEVV TLWYRPPDVL FGAKLYSTSI 180

DMWSAGCIFA ELANAGRPLF PGNDVDDQLK RIFRDTLLGT PTEEQWPAMT KLPDYKPYPM 240

YPATTSLVNV VPKLNATGRD LLQNLLKCNP IQRISAEEAL QHPYF 285

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013