EKS-MYL-00287

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-MYL-00287

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
TKL/STKR	388.2	2.2E-116	206	504	299

Status

Unreviewed

Ensembl Protein

ENSMLUP00000013454

UniProt Accession

G1PQS5;

Protein Name

Protein Synonyms/Alias

Gene Name

BMPR2

Gene Synonyms/Alias

BMPR2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMLUG00000014783	ENSMLUP00000013454	ENSMLUT00000014786

Organism

Myotis lucifugus

Functional Description

Protein Length

1041

Protein Sequence
(FASTA)

ITSSHTKPAW AVAPSWLVHL FVLESMDLAS QNQERLCAFK DPYQQDLGIG ESRISHENGT 60

ILCSKGSTCY GLWEKSKGDI NLVKQGCWSH LGDPEECHHE ECIVTTTPPS IQNGTYRFCC 120

CSTDLCNVNF TENFPPPDTT PLSPPHSFNR DETIIIALAS VSVLAVLIVA LCFGYRMLTG 180

DRKQGLHSMN MMEAAASEPS LDLDNLKLLE LIGRGRYGAV YKGSLDERPV AVKMFSFANR 240

QNFINEKNIY RVPLMEHDNI ARFIVGDERV TADGRMEYLL VMEYYPNGSL CKYLSLHTSD 300

WVSSCRLAHS VTRGLAYLHT ELPRGDHYKP AISHRDLNSR NVLVKNDGTC VISDFGLSMR 360

LTGNRLVRPG EEDNAAISEV GTIRYMAPEV LEGAVNLRDC ESALKQVDMY ALGLIYWEIF 420

MRCTDLFPGE SVPEYQMAFQ TEVGNHPTFE DMQVLVSREK QRPKFPEAWK ENSLAVRSLK 480

ETIEDCWDQD AEARLTAQCA EERMAELMMI WERNKSVSPT VNPMSTAMQN ERNLSHSRRV 540

PKIGPYPDYS SSSYIEDSIH HTDSIVKNIS SEHSMSSTPL TTGEKNRNSI NYERQQAQAR 600

IPSPETSVTS LSTNTTTTNT TGLTPSTGMT TISEMPYPDE TNLHATNVSQ PIGPTPVCLQ 660

LTEEDLETNK LDPKEVDKNL KESSDENLME HSLKQFSGPD PLSSTSSSLL YPLIKLAVEV 720

TGQQDFTQAV NGQACLIPDV PPAQLYPLPK QQNLPKRPTS LPLNTKNSTK EPRLKFGSKH 780

KSNLKQVETG VAKMNTINAV EPHVVTVTMN GVAGRNHNVN SHAATAQYAN GAIPSGQTAN 840

TVAHRAQEML QNQFIGEDTR LNINSSPDEH EPLLRREQQA GHDEGVLDRL VDRRERPLEG 900

GRTNSNNNNS NPCLEQDVLT QGVPSTVVDP GPSKPRRAQR PNSLDLSATN ILDGSGLQLG 960

ESTQDGKSGS GEKIKKRVKT PYSLKRWRPS TWVISTEQLD CEVNNNGSDR AAHSKSSTTV 1020

YLADGGTATT MVSKDVGMNC L 1041

Nucleotide Sequence
(FASTA)

ATCACTAGTA GCCATACCAA ACCGGCTTGG GCAGTAGCCC CCTCTTGGCT GGTTCATTTG 60

TTTGTTTTAG AGAGCATGGA TTTAGCTTCT CAGAATCAAG AACGTCTATG TGCATTTAAA 120

GATCCATATC AACAAGACCT TGGGATAGGC GAGAGTCGAA TCTCTCATGA AAATGGAACC 180

ATATTATGCT CAAAAGGTAG CACCTGCTAT GGACTCTGGG AGAAGTCAAA AGGGGACATC 240

AATCTCGTAA AACAAGGATG TTGGTCTCAC CTTGGAGATC CTGAAGAGTG TCACCATGAA 300

GAATGCATTG TAACTACCAC CCCTCCCTCA ATTCAGAATG GAACATATCG TTTCTGCTGC 360

TGTAGCACAG ACTTGTGTAA TGTCAACTTT ACCGAGAATT TTCCACCTCC AGATACAACA 420

CCACTAAGTC CACCTCATTC ATTTAACCGA GATGAAACAA TAATCATTGC TTTAGCATCA 480

GTCTCTGTAT TAGCTGTTTT GATAGTTGCC TTATGCTTCG GATACAGGAT GCTGACAGGA 540

GACCGTAAAC AAGGTCTGCA CAGTATGAAC ATGATGGAGG CAGCAGCATC AGAGCCTTCT 600

CTTGACCTAG ATAATCTGAA ACTGTTGGAG CTGATTGGCC GGGGTCGATA TGGAGCAGTA 660

TATAAAGGTT CCTTAGATGA GCGTCCAGTT GCTGTAAAAA TGTTTTCCTT CGCAAACCGT 720

CAAAATTTTA TCAATGAAAA GAACATTTAC AGAGTGCCTT TGATGGAACA TGACAACATT 780

GCTCGCTTTA TAGTTGGAGA TGAAAGAGTC ACTGCTGATG GACGCATGGA GTATTTGCTT 840

GTGATGGAGT ACTATCCCAA TGGATCTCTA TGCAAGTATC TTAGTCTCCA TACAAGTGAT 900

TGGGTAAGCT CTTGCCGTCT GGCTCATTCT GTGACTAGAG GACTGGCTTA TCTTCATACA 960

GAATTACCAC GAGGAGATCA TTATAAACCT GCAATTTCCC ATCGAGATTT AAACAGCAGA 1020

AATGTCCTGG TGAAAAATGA TGGAACTTGT GTTATTAGTG ACTTTGGGTT GTCCATGAGG 1080

CTGACTGGAA ATAGACTGGT ACGCCCAGGA GAAGAAGATA ATGCAGCCAT AAGTGAGGTT 1140

GGTACAATCA GATATATGGC ACCAGAAGTT CTAGAAGGAG CTGTGAACCT GAGGGACTGT 1200

GAATCAGCTT TGAAACAAGT AGACATGTAT GCTCTTGGAC TAATCTATTG GGAGATATTT 1260

ATGAGATGTA CAGACCTCTT CCCAGGTGAA TCTGTACCAG AATACCAGAT GGCTTTTCAG 1320

ACAGAAGTTG GAAACCATCC CACTTTTGAA GATATGCAGG TTCTGGTGTC TAGGGAAAAA 1380

CAGAGACCGA AGTTCCCAGA AGCTTGGAAA GAAAATAGCC TGGCAGTGAG GTCACTCAAG 1440

GAGACAATCG AAGACTGTTG GGACCAGGAT GCAGAGGCTC GGCTTACTGC ACAGTGTGCT 1500

GAGGAGAGGA TGGCTGAACT TATGATGATA TGGGAAAGAA ACAAATCCGT GAGCCCAACA 1560

GTCAATCCGA TGTCTACTGC AATGCAGAAT GAGCGCAACC TGTCACACAG TAGGCGTGTG 1620

CCAAAGATTG GCCCTTATCC AGATTATTCT TCTTCCTCAT ACATTGAAGA CTCTATCCAT 1680

CACACTGACA GCATTGTGAA GAATATTTCC TCTGAGCATT CGATGTCTAG CACACCTTTG 1740

ACCACAGGGG AAAAGAACCG AAACTCAATT AACTACGAAC GACAGCAAGC ACAAGCTCGA 1800

ATTCCTAGCC CTGAAACAAG TGTCACCAGC CTGTCCACCA ACACAACCAC CACCAACACC 1860

ACTGGCCTCA CTCCCAGCAC TGGCATGACC ACTATATCGG AGATGCCATA CCCAGATGAA 1920

ACAAATCTTC ATGCCACCAA TGTTTCACAG CCAATTGGGC CAACCCCTGT CTGCTTACAG 1980

TTGACAGAAG AAGACTTGGA GACCAACAAG CTAGACCCTA AAGAAGTTGA TAAGAACCTC 2040

AAAGAAAGTT CTGATGAGAA TCTCATGGAG CATTCTCTTA AGCAGTTCAG TGGGCCAGAC 2100

CCACTGAGCA GTACCAGTTC TAGCTTGCTT TACCCACTAA TAAAGCTTGC AGTAGAAGTC 2160

ACTGGGCAGC AGGATTTCAC ACAGGCTGTT AATGGCCAAG CATGTTTAAT TCCTGATGTC 2220

CCACCTGCTC AGCTCTATCC TCTCCCCAAG CAACAGAACC TTCCCAAGAG ACCTACTAGT 2280

TTGCCTTTAA ACACCAAAAA TTCAACAAAG GAGCCCCGGC TGAAATTTGG CAGCAAGCAC 2340

AAATCAAACT TGAAACAAGT AGAAACTGGA GTTGCCAAGA TGAACACCAT CAATGCTGTA 2400

GAACCTCATG TGGTTACGGT TACCATGAAT GGGGTGGCAG GTAGAAATCA CAACGTTAAC 2460

TCCCATGCTG CCACTGCTCA GTATGCGAAT GGGGCAATAC CATCTGGCCA GACAGCCAAC 2520

ACAGTGGCAC ATAGGGCCCA AGAAATGCTG CAGAATCAGT TCATTGGTGA GGACACCAGG 2580

CTGAATATTA ATTCCAGTCC TGATGAGCAT GAACCTTTAT TGAGGCGAGA GCAACAGGCT 2640

GGCCATGATG AAGGTGTTCT GGATCGTCTT GTGGACAGGA GGGAACGGCC GCTGGAAGGT 2700

GGCCGAACTA ATTCCAATAA CAACAACAGT AATCCATGTT TAGAGCAAGA TGTTCTTACA 2760

CAGGGTGTTC CAAGCACAGT TGTAGATCCT GGACCATCAA AACCCAGAAG AGCACAGAGA 2820

CCTAATTCTT TAGATCTTTC AGCCACAAAT ATCCTTGATG GCAGCGGTTT GCAATTAGGT 2880

GAGTCAACAC AAGATGGCAA ATCAGGATCT GGTGAAAAGA TCAAGAAACG TGTGAAAACT 2940

CCGTATTCTC TTAAGCGGTG GCGCCCCTCC ACCTGGGTTA TCTCCACTGA ACAGCTGGAC 3000

TGTGAGGTCA ACAACAATGG CAGTGACAGG GCAGCCCATT CCAAATCTAG CACCACCGTT 3060

TACCTTGCAG ACGGAGGCAC TGCCACCACC ATGGTGTCTA AAGATGTAGG AATGAACTGT 3120

CTGTGA 3126

Domain Profile

S: 1     lklleligkGrygeVwkaklrgeevAvKifstedeaswkrEkeiyqtvllrhenilqfia  60

         lkllelig+Gryg+V+k++l+++ vAvK+fs ++++++ +Ek+iy+++l++h+ni +fi+

Q: 206   LKLLELIGRGRYGAVYKGSLDERPVAVKMFSFANRQNFINEKNIYRVPLMEHDNIARFIV  265

         6899********************************************************

S: 61    adk.keedsltelllvteyhekgsLsdyLkretldveellrlalslasGlahLHeeivgt  119

          d+  ++d ++e+llv+ey+++gsL++yL+ +t+d+ +++rla+s+++Gla+LH+e++

Q: 266   GDErVTADGRMEYLLVMEYYPNGSLCKYLSLHTSDWVSSCRLAHSVTRGLAYLHTELPRG  325

         **9999**************************************************9766

S: 120   kgkkKpaiaHRDlkskNilvkkdltcciaDlGLalkleeekee....ldlaansqvGtkR  175

          +++Kpai+HRDl+s+N+lvk+d+tc+i+D+GL+++l+ ++ +    +d+aa+s+vGt R

Q: 326   -DHYKPAISHRDLNSRNVLVKNDGTCVISDFGLSMRLTGNRLVrpgeEDNAAISEVGTIR  384

         .46***********************************999877787999**********

S: 176   YmaPEvleealnlkdfe.afkraDvYslgLvlWEvasRcee..vdeeveeyklpfeevvg  232

         YmaPEvle+a+nl+d+e a+k++D+Y+lgL++WE+++Rc++  ++e+v+ey+++f+++vg

Q: 385   YMAPEVLEGAVNLRDCEsALKQVDMYALGLIYWEIFMRCTDlfPGESVPEYQMAFQTEVG  444

         *****************99*****************************************

S: 233   sdPsleemkevvvekklrPkipeawkkke.alkelsklleecWdadpeaRltalrvkkrl  291

         ++P++e+m+ +v ++k+rPk+peawk+++ a+++l++++e+cWd+d+eaRlta++ ++r+

Q: 445   NHPTFEDMQVLVSREKQRPKFPEAWKENSlAVRSLKETIEDCWDQDAEARLTAQCAEERM  504

         ***************************9999*************************9987

Domain Sequence
(FASTA)

LKLLELIGRG RYGAVYKGSL DERPVAVKMF SFANRQNFIN EKNIYRVPLM EHDNIARFIV 60

GDERVTADGR MEYLLVMEYY PNGSLCKYLS LHTSDWVSSC RLAHSVTRGL AYLHTELPRG 120

DHYKPAISHR DLNSRNVLVK NDGTCVISDF GLSMRLTGNR LVRPGEEDNA AISEVGTIRY 180

MAPEVLEGAV NLRDCESALK QVDMYALGLI YWEIFMRCTD LFPGESVPEY QMAFQTEVGN 240

HPTFEDMQVL VSREKQRPKF PEAWKENSLA VRSLKETIED CWDQDAEARL TAQCAEERM 299

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0016020	; C:membrane
GO:0005524	; F:ATP binding
GO:0005024	; F:transforming growth factor beta-activated receptor activity
GO:0007178	; P:transmembrane receptor protein serine/threonine kinase signaling pathway

KEGG

InterPros

IPR000472	; Activin_rcpt.
IPR015770	; BMPRII.
IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.

Pfam

PF01064	; Activin_recp; 1.
PF00069	; Pkinase; 1.

SMARTs

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.

Prints

Created Date

20-Feb-2013