EKS-MYL-00193

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-MYL-00193

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
TK/Ryk	484.4	8.4E-146	257	525	269

Status

Unreviewed

Ensembl Protein

ENSMLUP00000014661

UniProt Accession

G1PTT7;

Protein Name

Protein Synonyms/Alias

Gene Name

RYK

Gene Synonyms/Alias

RYK;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMLUG00000016087	ENSMLUP00000014661	ENSMLUT00000016093

Organism

Myotis lucifugus

Functional Description

Protein Length

536

Protein Sequence
(FASTA)

LGLDAELYYV RNDLVSHYAL SFNLLVPSET NFLHFTWHAK SKVEYKLGFQ VDNFVAMDMP 60

QVNISAQGEV PRTLSVFRVE LSCTGKVDSE VMILMQLNLT VTSSKNFTVL NFKRRKMCYK 120

KLEEVKTSAL DKNTSRTIYD PVHAAPTTST RVFYISVGVC CAVIFLVAII LAVLHLHSMK 180

RIELDDSISA SSSSQGLSQP STQTTQYLRA DTPNNATPIT SSSGYPTLRI EKNDLRSVTL 240

LEAKAKVKDI AISRERITLK DVLQEGTFGR IFHGILIDEK DPNKEKQAFV KTVKDVDQAS 300

EIQVTMMLTE SCKLRGLHHR NLLPITHVCI EEGEKPMVIL PYMNWGNLKL FLRQCKLVEA 360

NNPQAISQQD LVHMAIQIAC GMSYLARREV IHKDLAARNC VIDDTLQVKI TDNALSRDLF 420

PMDYHCLGDN ENRPVRWMAL ESLVNNEFSS ASDVWAFGVT LWELMTLGQT PYVDIDPFEM 480

AAYLKDGYRI AQPINCPDEL FAVMACCWAL DPEERPKFQQ LVQCLTEFHA ALGAYV 536

Nucleotide Sequence
(FASTA)

CTAGGTCTCG ATGCAGAACT TTATTATGTG AGAAATGACC TTGTTAGTCA CTACGCTCTA 60

TCCTTTAACC TGTTAGTACC CAGTGAGACA AATTTCCTGC ACTTCACTTG GCATGCAAAG 120

TCCAAGGTTG AATATAAGCT GGGATTCCAA GTAGACAACT TTGTGGCAAT GGACATGCCC 180

CAGGTCAACA TTTCTGCTCA GGGGGAAGTT CCACGCACTT TATCAGTGTT CCGGGTTGAG 240

CTTTCCTGTA CTGGCAAAGT AGATTCTGAG GTTATGATTC TAATGCAGCT CAACTTGACA 300

GTAACCTCTT CAAAAAACTT TACAGTCTTA AATTTTAAGC GAAGGAAAAT GTGCTACAAA 360

AAACTTGAAG AAGTAAAAAC TTCAGCATTG GACAAAAACA CTAGCAGAAC TATTTATGAT 420

CCTGTACATG CAGCTCCCAC CACTTCTACG CGTGTGTTTT ATATCAGCGT AGGGGTTTGC 480

TGTGCAGTAA TATTTCTCGT AGCAATAATA TTAGCTGTTT TGCACCTTCA TAGTATGAAA 540

AGGATTGAAC TGGATGACAG CATCAGTGCC AGCAGCAGTT CCCAAGGGCT GTCTCAGCCA 600

TCTACCCAGA CGACTCAGTA TCTGAGAGCC GACACACCCA ACAATGCAAC TCCTATCACC 660

AGCTCCTCAG GTTATCCTAC CCTGCGAATA GAGAAGAACG ACCTAAGAAG TGTCACTCTT 720

TTGGAGGCCA AAGCTAAGGT GAAGGATATA GCAATCTCCA GGGAGAGGAT AACTCTAAAA 780

GATGTACTCC AAGAAGGTAC TTTTGGGCGT ATTTTCCATG GGATTTTAAT AGATGAAAAA 840

GATCCAAATA AAGAAAAGCA AGCATTTGTA AAAACAGTTA AAGACGTAGA TCAAGCTTCT 900

GAAATTCAGG TGACAATGAT GCTCACTGAA AGTTGTAAGC TGCGAGGCCT TCATCACAGA 960

AATCTTCTTC CTATTACCCA TGTGTGTATA GAAGAAGGAG AAAAGCCCAT GGTGATATTG 1020

CCTTACATGA ATTGGGGGAA TCTAAAATTG TTTTTACGGC AGTGCAAATT AGTAGAGGCC 1080

AATAATCCTC AGGCAATTTC TCAGCAAGAC CTGGTACACA TGGCTATTCA GATTGCCTGT 1140

GGAATGAGCT ATCTGGCCAG AAGGGAAGTC ATCCACAAAG ACCTGGCTGC TAGGAACTGT 1200

GTCATTGATG ACACACTTCA AGTTAAGATC ACAGACAATG CCCTCTCCAG AGACTTGTTC 1260

CCCATGGACT ACCACTGTCT GGGGGACAAC GAAAACAGGC CAGTTCGGTG GATGGCTTTG 1320

GAAAGTCTGG TTAATAATGA GTTCTCCAGC GCTAGTGATG TGTGGGCCTT CGGAGTGACG 1380

CTGTGGGAGC TCATGACTCT GGGCCAAACG CCCTATGTGG ACATCGACCC CTTTGAGATG 1440

GCTGCGTACC TGAAAGACGG TTACCGAATA GCCCAGCCTA TCAACTGTCC TGATGAACTA 1500

TTTGCTGTGA TGGCTTGTTG CTGGGCCTTG GATCCGGAGG AGAGGCCCAA GTTCCAGCAG 1560

CTGGTACAGT GTCTCACGGA GTTCCACGCA GCCCTGGGGG CCTATGTTTG A 1611

Domain Profile

S: 1     lrlkellqeGtfGriyrGkledekdtnkekavlvktvk..dqaseiqvalllqealllyg  58

         ++lk++lqeGtfGri++G+l dekd+nkek+++vktvk  dqaseiqv+++l+e+++l+g

Q: 257   ITLKDVLQEGTFGRIFHGILIDEKDPNKEKQAFVKTVKdvDQASEIQVTMMLTESCKLRG  316

         6799*********************************94459******************

S: 59    vshrnilsvllvsieeaekPlvvypalnkgnlkkflricklkdkekaqalstkqlvelai  118

         ++hrn+l++++v+iee ekP+v++p++n+gnlk flr+ckl++++++qa+s+++lv++ai

Q: 317   LHHRNLLPITHVCIEEGEKPMVILPYMNWGNLKLFLRQCKLVEANNPQAISQQDLVHMAI  376

         ************************************************************

S: 119   qiasalaylhkrevvhkdiaarncviddelqvkltdsalsrdlfPadydclGdnenrPlk  178

         qia++++yl++rev+hkd+aarncvidd+lqvk+td+alsrdlfP+dy+clGdnenrP++

Q: 377   QIACGMSYLARREVIHKDLAARNCVIDDTLQVKITDNALSRDLFPMDYHCLGDNENRPVR  436

         ************************************************************

S: 179   WlslealqkeeyssasdvWalGvllWelvtlgksPyaeidpfeleaylkdGyrlaqPvnc  238

         W++le+l+++e+ssasdvWa+Gv+lWel+tlg++Py++idpfe++aylkdGyr+aqP+nc

Q: 437   WMALESLVNNEFSSASDVWAFGVTLWELMTLGQTPYVDIDPFEMAAYLKDGYRIAQPINC  496

         ************************************************************

S: 239   PdelftvmaccWallpeerPsfeqlvscl  267

         Pdelf+vmaccWal+peerP+f+qlv+cl

Q: 497   PDELFAVMACCWALDPEERPKFQQLVQCL  525

         ****************************8

Domain Sequence
(FASTA)

ITLKDVLQEG TFGRIFHGIL IDEKDPNKEK QAFVKTVKDV DQASEIQVTM MLTESCKLRG 60

LHHRNLLPIT HVCIEEGEKP MVILPYMNWG NLKLFLRQCK LVEANNPQAI SQQDLVHMAI 120

QIACGMSYLA RREVIHKDLA ARNCVIDDTL QVKITDNALS RDLFPMDYHC LGDNENRPVR 180

WMALESLVNN EFSSASDVWA FGVTLWELMT LGQTPYVDID PFEMAAYLKD GYRIAQPINC 240

PDELFAVMAC CWALDPEERP KFQQLVQCL 269

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004713	; F:protein tyrosine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR001245	; Ser-Thr/Tyr_kinase_cat_dom.
IPR008266	; Tyr_kinase_AS.
IPR020635	; Tyr_kinase_cat_dom.
IPR003306	; WIF.

Pfam

PF07714	; Pkinase_Tyr; 1.
PF02019	; WIF; 1.

SMARTs

SM00219

; TyrKc; 1.

Prosites

PS50011	; PROTEIN_KINASE_DOM; 1.
PS00109	; PROTEIN_KINASE_TYR; 1.
PS50814	; WIF; 1.

Prints

PR00109

; TYRKINASE.

Created Date

20-Feb-2013