EKS-MYL-00389

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-MYL-00389

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
STE/STE11	339.6	1.5E-101	1049	1312	264

Status

Unreviewed

Ensembl Protein

ENSMLUP00000014709

UniProt Accession

G1PTY0;

Protein Name

Protein Synonyms/Alias

Gene Name

YSK4

Gene Synonyms/Alias

YSK4;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMLUG00000016142	ENSMLUP00000018296	ENSMLUT00000022730
ENSMLUG00000016142	ENSMLUP00000014709	ENSMLUT00000016145

Organism

Myotis lucifugus

Functional Description

Protein Length

1316

Protein Sequence
(FASTA)

MNSMPKPDEH AESLLDICHD TNSSPTNMTV TQNQNILLQS VSSSEEFDQD DGCSHSILVK 60

EGGDPSGGGR DWQPRTEGVE IIVTFPREVH HAQEMSQEDL KESNQITSEH QAWAQAPSVP 120

LPNEIEMMDF GTKMPTTQPL LLGTEESPKE LCDENLVLLP RPCLEAHISK SVARDVPRPL 180

RGQQRKSEEF SASDMKYSSR RIEFPLPPLS FLPMRPGLLT IPPNHKYQKE REKNLDSFEP 240

KLSEPISRSD ELRPPNKQLE ASFKVFVDQT LGSSNSSIWS RNMCSFGKAN HHRQHLKMEE 300

NGKLKETEGC DKIPISHFEK RQSLVSFENL KEGNFPADRE VDMDWPGSEM RKAEENSQCL 360

SSGKIEGSVA RNYEQNSDVG CTMPIKSQEA QHSETTLSKD KGTGNDKDDS KSASVHKGEL 420

IEPNHILEEF TVLKSLYNVI PDSPIERLLE DHNNMEKHTK ISIAEASKSG MNGIVPLIHI 480

TFPGDETPKE PAVAKPSLQK RKGALHNNSF NIRAHQENDR RMMKTHRNKF DPKTKTSNRT 540

PQNGMISIDG PMKPTMHKTS IKTQVFPSLG LVEPRPRQSP KFQRRMPQIE KKQSTYWALK 600

PKKQTFPCIC KNPGIKKSLA PIPVQPIEPR LNYLDLKYSD MFKEINSTAN GPGIYEMFGT 660

PVYCHMREAE RHENKYYREI CSAPSGRCIN SKCRSSHGER SSNSRTRFSQ KRQHVKPPKA 720

LLGIKHRHKS LISKEKGCKA VGSKLQDTEN GGGISEPEWQ MKSLGNDFLS SKDEIQPMNF 780

TQTHEQSTEQ NKFLPVSDLS IVEEVSMEES TDEGDISNNQ ILPTSLRDLH QLEELHHQTP 840

FSLSEYSRAV PSEKSFNKHV PQEKQNIASL GKNIANQILM NDVEFDSLID TSKTLTNLSF 900

QDTQGSASSQ TYQHWAHSLD HDSLASKPIT HQTFEKTLND ANSISQEILD SIKSQELTDE 960

LLGCLAEKLL ALDEKDNACQ IVADETDPEN INLIFSRRGN TMQELGGETT NVKIQRHSNG 1020

FGIYDEDKFL NDKKIFSENS LKYEEAILWT KGEILGKGAY GTVYCGLTSQ GELIAVKQVA 1080

LDTSDKLSTE REYRKLQEEV DLLKALKHVN IVAYLGTCLE KNTVSIFMEF VPGGSISSII 1140

NRFGPLPEMV FCKYTEQILQ GVAYLHENCV VHRDIKGNNV MLMPTGIIKL IDFGCAKRLA 1200

WAGVNGTHSD MLKSMHGTPY WMAPEVINES GYGRKSDIWS VGCTVFEMAT GKPPLASMDR 1260

VAAMFYIGAH RGLMPPLPEH FSENAADFVR VCLTRDQHER PSAVQLLKHS FLKRSY 1316

Nucleotide Sequence
(FASTA)

ATGAATTCTA TGCCAAAACC AGACGAACAT GCTGAATCAT TGCTTGACAT TTGTCATGAT 60

ACAAACTCTT CTCCAACCAA TATGACAGTT ACCCAAAACC AAAATATACT CTTGCAAAGC 120

GTCAGCAGCA GTGAGGAGTT TGACCAAGAT GATGGCTGCA GTCATTCCAT ATTGGTTAAA 180

GAAGGAGGAG ATCCGAGTGG TGGTGGACGA GATTGGCAAC CCAGGACAGA AGGTGTCGAG 240

ATTATTGTTA CTTTTCCAAG AGAAGTCCAT CATGCCCAAG AGATGAGCCA AGAAGATTTA 300

AAAGAAAGCA ATCAGATAAC CTCAGAGCAT CAAGCATGGG CACAAGCACC TTCTGTTCCT 360

CTTCCAAATG AAATTGAGAT GATGGACTTC GGAACAAAGA TGCCAACCAC ACAGCCTTTA 420

CTCCTGGGGA CAGAAGAAAG CCCCAAGGAG CTCTGCGATG AGAACCTGGT CTTGTTACCA 480

AGACCTTGCT TAGAAGCCCA CATCTCCAAG TCTGTAGCCA GAGATGTGCC TCGCCCTCTG 540

AGAGGCCAGC AGAGAAAATC TGAAGAGTTT TCTGCCTCTG ATATGAAGTA CAGCAGTCGA 600

AGAATTGAGT TCCCTCTGCC ACCATTGTCA TTCTTGCCCA TGAGACCTGG TCTTCTTACT 660

ATCCCCCCAA ATCACAAGTA TCAAAAAGAG AGAGAGAAAA ATCTTGATTC TTTCGAACCT 720

AAGCTCTCCG AGCCTATTAG TCGATCTGAT GAATTAAGAC CACCAAACAA GCAACTGGAA 780

GCCTCATTCA AGGTGTTTGT GGATCAGACT CTCGGGTCCT CCAATAGCTC TATTTGGTCC 840

AGAAACATGT GCTCTTTTGG GAAAGCTAAC CATCACAGGC AACACCTGAA GATGGAGGAG 900

AATGGGAAAT TGAAGGAAAC AGAAGGATGT GACAAAATTC CAATCTCTCA CTTTGAAAAA 960

AGGCAGTCTT TGGTATCCTT TGAGAATTTG AAGGAAGGCA ACTTTCCTGC AGACAGGGAA 1020

GTGGATATGG ACTGGCCTGG CAGTGAAATG AGAAAAGCAG AAGAGAACTC TCAATGTCTT 1080

TCATCGGGGA AGATAGAGGG TTCCGTAGCC AGAAACTATG AACAAAATTC AGACGTTGGA 1140

TGTACCATGC CAATCAAGTC CCAAGAAGCC CAGCATTCAG AAACAACTCT AAGCAAGGAT 1200

AAAGGTACTG GAAATGATAA AGATGATTCA AAAAGCGCTT CAGTGCATAA AGGTGAACTA 1260

ATTGAACCAA ACCATATTTT AGAGGAATTT ACTGTACTTA AAAGTTTGTA CAATGTAATT 1320

CCTGACAGCC CCATTGAAAG GCTGCTGGAA GATCATAACA ACATGGAGAA ACATACAAAA 1380

ATATCAATAG CAGAGGCAAG CAAATCAGGA ATGAATGGGA TAGTGCCTCT TATCCACATC 1440

ACTTTCCCTG GAGATGAGAC TCCCAAGGAA CCAGCCGTAG CCAAGCCAAG CCTCCAAAAA 1500

AGAAAGGGCG CCCTTCATAA CAACAGCTTC AACATACGTG CACACCAAGA AAATGACAGG 1560

CGTATGATGA AAACCCATAG AAATAAGTTC GATCCAAAAA CCAAGACCAG TAACAGGACA 1620

CCTCAGAATG GCATGATTTC CATTGATGGT CCCATGAAGC CTACCATGCA TAAAACCAGC 1680

ATAAAGACTC AAGTTTTCCC TTCTTTGGGG CTTGTTGAGC CCAGACCTCG GCAATCACCC 1740

AAGTTTCAAA GGAGAATGCC TCAGATAGAA AAAAAGCAAT CAACTTACTG GGCTCTGAAG 1800

CCTAAAAAGC AAACATTTCC TTGCATCTGT AAAAATCCAG GAATAAAAAA GTCTTTAGCT 1860

CCTATCCCTG TTCAACCAAT AGAGCCGAGA CTAAATTACC TAGATCTTAA GTATAGTGAT 1920

ATGTTCAAAG AAATCAACTC AACTGCTAAT GGACCTGGAA TCTATGAAAT GTTTGGGACC 1980

CCAGTTTATT GTCACATGAG AGAGGCTGAA CGGCATGAAA ACAAATATTA CCGGGAGATA 2040

TGCTCAGCTC CGTCAGGCAG ATGTATCAAC AGTAAATGTA GATCTTCACA CGGTGAGAGG 2100

AGCAGCAATA GCAGAACAAG GTTTTCTCAG AAAAGACAAC ATGTTAAGCC CCCAAAGGCT 2160

TTGCTTGGAA TTAAACACAG GCACAAAAGT TTAATTTCCA AAGAAAAGGG TTGCAAGGCT 2220

GTAGGTAGCA AACTACAAGA CACTGAAAAT GGTGGTGGTA TTTCAGAACC AGAGTGGCAG 2280

ATGAAGTCTT TGGGAAATGA CTTTCTGTCT TCCAAAGACG AAATTCAGCC CATGAACTTT 2340

ACTCAGACTC ATGAACAGTC CACTGAACAG AACAAATTCC TTCCTGTCTC AGATTTGTCC 2400

ATTGTTGAAG AAGTCTCTAT GGAAGAGTCC ACCGATGAAG GAGACATTTC TAACAATCAA 2460

ATTCTTCCCA CAAGCCTCAG GGATCTGCAT CAACTTGAAG AGCTACATCA CCAGACCCCC 2520

TTTTCCCTTT CAGAATACAG CAGGGCAGTG CCCAGTGAGA AGAGTTTCAA CAAACATGTA 2580

CCACAAGAAA AGCAGAATAT AGCATCTCTT GGTAAAAATA TTGCCAACCA AATCTTAATG 2640

AATGATGTAG AGTTTGACAG TTTGATAGAC ACATCTAAAA CACTTACGAA TCTCTCTTTC 2700

CAAGACACAC AAGGAAGTGC ATCTTCTCAA ACATATCAAC ATTGGGCACA TTCTTTGGAT 2760

CATGATAGTT TAGCTAGTAA GCCAATTACA CACCAAACAT TTGAAAAAAC TTTAAATGAT 2820

GCAAATTCAA TTTCCCAAGA AATCCTCGAC TCTATAAAGA GCCAAGAATT GACAGATGAA 2880

CTATTAGGTT GTCTAGCTGA AAAACTACTA GCTCTTGATG AGAAAGATAA CGCTTGTCAG 2940

ATAGTGGCAG ATGAAACAGA TCCTGAAAAC ATAAATCTCA TCTTCAGTAG GAGAGGAAAT 3000

ACCATGCAAG AGTTGGGTGG AGAGACAACC AATGTCAAAA TACAGAGACA TAGTAATGGG 3060

TTCGGAATAT ATGACGAGGA TAAATTTCTC AATGACAAGA AAATATTTTC TGAAAATAGT 3120

TTAAAGTATG AAGAAGCCAT CCTGTGGACC AAGGGTGAGA TCCTTGGGAA GGGAGCCTAC 3180

GGCACAGTAT ATTGTGGTCT AACTAGCCAA GGAGAGCTAA TAGCTGTAAA ACAGGTGGCT 3240

TTGGATACCT CTGATAAATT ATCTACTGAA AGAGAATACC GGAAACTGCA GGAAGAAGTG 3300

GATTTGCTCA AAGCGCTGAA ACATGTCAAC ATTGTGGCCT ACTTGGGGAC ATGCTTGGAA 3360

AAAAACACTG TGAGCATTTT CATGGAGTTT GTTCCTGGTG GTTCAATCTC TAGTATTATC 3420

AACCGTTTTG GGCCATTGCC TGAGATGGTG TTCTGTAAAT ACACAGAACA AATTCTGCAA 3480

GGTGTTGCTT ATCTCCACGA GAACTGCGTG GTGCATCGAG ATATCAAAGG AAATAATGTT 3540

ATGCTCATGC CTACTGGAAT AATAAAACTG ATCGACTTTG GCTGTGCCAA ACGTTTGGCC 3600

TGGGCTGGCG TGAATGGCAC TCACAGTGAC ATGCTTAAGT CCATGCATGG GACTCCCTAC 3660

TGGATGGCCC CAGAGGTCAT CAATGAGTCT GGCTATGGGA GGAAGTCGGA CATCTGGAGT 3720

GTGGGCTGCA CTGTGTTTGA GATGGCCACA GGCAAGCCTC CGCTGGCATC CATGGACCGG 3780

GTGGCAGCCA TGTTCTACAT TGGCGCACAC CGGGGGCTGA TGCCACCCTT ACCCGAACAC 3840

TTCTCAGAAA ACGCAGCGGA CTTTGTGCGC GTGTGCCTAA CCAGGGACCA GCACGAGCGC 3900

CCCTCTGCTG TTCAGCTCCT GAAGCACTCC TTCTTGAAGA GAAGTTACTG A 3951

Domain Profile

S: 1     wqkrevigkGsfgsvyaaldvdtgellavKeveikp.ekksekkevkalkeEikllkelk  59

         w+k+e++gkG++g+vy++l+ ++gel+avK+v++++ +k s+++e+++l+eE++llk+lk

Q: 1049  WTKGEILGKGAYGTVYCGLT-SQGELIAVKQVALDTsDKLSTEREYRKLQEEVDLLKALK  1107

         89*****************8.89***********8615556777****************

S: 60    HenivkyyGveveeeelkiflEyvegGslssllekygkleesvikkytkqileglayLHe  119

         H niv y+G++ e+++++if+E+v+gGs+ss+++++g+l e+v++kyt+qil+g+ayLHe

Q: 1108  HVNIVAYLGTCLEKNTVSIFMEFVPGGSISSIINRFGPLPEMVFCKYTEQILQGVAYLHE  1167

         ************************************************************

S: 120   kkivHRDiKgaNilldssgvvklsDFGaskrlaelntkaae...lesltGtlaymaPEvi  176

         +++vHRDiKg+N++l+ +g++kl DFG++krla++  + ++   l+s++Gt+++maPEvi

Q: 1168  NCVVHRDIKGNNVMLMPTGIIKLIDFGCAKRLAWAGVNGTHsdmLKSMHGTPYWMAPEVI  1227

         **********************************999988877899**************

S: 177   kkkekgygrkaDiWslgcvviemltgkrPfaeldeelaimfkvgakk.tkPeipeklsee  235

         +++  gygrk+DiWs+gc+v+em+tgk+P a++ +++a+mf +ga++  +P++pe++se+

Q: 1228  NES--GYGRKSDIWSVGCTVFEMATGKPPLASM-DRVAAMFYIGAHRgLMPPLPEHFSEN  1284

         988..****************************.9*********99979***********

S: 236   gkdflekcleldpkkrpsaeeLLkhefl  263

         + df++ cl++d+++rpsa +LLkh+fl

Q: 1285  AADFVRVCLTRDQHERPSAVQLLKHSFL  1312

         **************************96

Domain Sequence
(FASTA)

WTKGEILGKG AYGTVYCGLT SQGELIAVKQ VALDTSDKLS TEREYRKLQE EVDLLKALKH 60

VNIVAYLGTC LEKNTVSIFM EFVPGGSISS IINRFGPLPE MVFCKYTEQI LQGVAYLHEN 120

CVVHRDIKGN NVMLMPTGII KLIDFGCAKR LAWAGVNGTH SDMLKSMHGT PYWMAPEVIN 180

ESGYGRKSDI WSVGCTVFEM ATGKPPLASM DRVAAMFYIG AHRGLMPPLP EHFSENAADF 240

VRVCLTRDQH ERPSAVQLLK HSFL 264

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Nomascus leucogenys"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013