EPS-MYL-00122

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-MYL-00122

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPP/PP7	280.3	1.7E-83	131	334	204

Status

Unreviewed

Ensembl Protein

ENSMLUP00000014860

UniProt Accession

G1PUB0;

Protein Name

Serine/threonine-protein phosphatase

Protein Synonyms/Alias

Gene Name

PPEF2

Gene Synonyms/Alias

PPEF2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMLUG00000016301	ENSMLUP00000014860	ENSMLUT00000016309

Organism

Myotis lucifugus

Functional Description

Protein Length

742

Protein Sequence
(FASTA)

MGSGASTHHH FAFQNAEKAF KAAALIQRWY RRYMARLEMR RQCTWSIFQS MEYAGQQDQV 60

KLHDFFSYLV DHFTPSSHSE RDFLNRMFTE ERIPRDSEVE KCSDYESIEV PDNYTGPRLS 120

FPLLPDHATA LVEAFRLKQQ LHARYVLNLL HETRKHLVQL PNINRVSTCY SEEITVCGDL 180

HGQLDDLIFI FYKNGLPSPE RAYVFNGDFV DRGKDSVEIL MVLFAFMLVY PKEFHLNRGN 240

HEDHMVNLRY GFTKEVMQKY KMHGKKILQR LQDVFCWLPL ATLVDEKVLI LHGGVSDTTD 300

LELLSKLERH KIVSTLRCKT RKENEKQAEE KGKAKQTSSA GSLSPWFLPQ SRSLPSSPLH 360

LSSHKTHKAG RSSSVPCSTP LDPRGLSRQA RRSVDLELER CRQQAGFPVI TEKEEPWVFN 420

PEADSAAGEL LEASQEEWRQ VVDILWSDPM AQEGCRANTV RGGGCYFGPN VTKQLLQKYN 480

LQFLIRSHEC KPEGYEFCHS RKVLTVFSAS NYYAVGSNRG AYVKLGPALA PHIVQYQANK 540

ATHMLTMRQR ISRVEESALR ALRGKLFAHS SDLLEEFKKH DNGNTGSITL SDWAAAVESV 600

LHLGLPWRML RPQLVSSSTD NMLEYKSWLE DLAKEQLSHE NIQSSLLETL YRNRSNLETI 660

FRIIDSDHSG FISLDEFRQT WKLFSSHMKM DITDDGICDL ARSIDFNKDG HIDINEFLEA 720

VRLVEQSCSE GDAADCPQAT NT 742

Nucleotide Sequence
(FASTA)

ATGGGAAGTG GCGCCTCAAC CCACCATCAT TTTGCTTTCC AGAATGCAGA AAAAGCCTTC 60

AAGGCGGCGG CCCTGATCCA GAGATGGTAC CGGCGCTACA TGGCACGCCT GGAGATGAGG 120

CGGCAGTGCA CCTGGAGCAT CTTCCAGTCC ATGGAGTACG CTGGGCAGCA AGACCAGGTC 180

AAGCTCCACG ATTTCTTCAG CTACCTTGTG GACCACTTCA CCCCCAGCAG TCACAGTGAG 240

AGGGACTTCC TGAACCGCAT GTTTACTGAG GAGAGAATCC CCCGGGACTC TGAGGTAGAG 300

AAATGCAGCG ACTATGAATC CATAGAGGTG CCAGACAATT ACACGGGGCC ACGCCTCTCC 360

TTCCCACTCC TTCCTGACCA CGCAACTGCC CTGGTGGAAG CTTTCAGACT GAAACAACAG 420

CTACATGCTC GCTATGTCTT GAATCTTTTG CATGAAACTA GAAAACATCT GGTACAGCTG 480

CCAAACATCA ATCGGGTCTC CACCTGTTAC AGTGAGGAGA TCACAGTGTG TGGAGATTTA 540

CATGGTCAGT TGGATGACTT AATATTCATA TTTTATAAGA ATGGCCTCCC ATCCCCAGAA 600

CGAGCCTATG TGTTCAACGG TGATTTTGTG GATCGAGGCA AGGATTCGGT AGAGATCCTG 660

ATGGTCCTTT TTGCCTTCAT GTTGGTTTAC CCCAAAGAGT TCCATCTTAA CCGAGGAAAC 720

CATGAGGACC ACATGGTGAA CTTACGATAT GGCTTCACCA AGGAAGTGAT GCAAAAATAT 780

AAGATGCATG GCAAGAAAAT ACTACAAAGA CTGCAAGATG TTTTCTGTTG GCTTCCACTG 840

GCCACGCTGG TGGATGAGAA AGTCCTGATT CTTCATGGTG GTGTGTCAGA CACGACTGAC 900

CTAGAGCTTT TGTCTAAACT AGAGAGGCAC AAGATTGTTT CCACCTTGAG GTGCAAAACA 960

AGAAAAGAGA ACGAGAAGCA AGCGGAGGAG AAGGGAAAAG CCAAGCAGAC GAGCTCTGCA 1020

GGGAGCCTCT CCCCGTGGTT TCTCCCCCAA AGCCGCTCTC TCCCCTCTTC GCCCCTTCAT 1080

CTCAGCTCCC ACAAGACCCA CAAAGCTGGC CGCTCCTCCA GCGTCCCCTG CAGCACCCCC 1140

CTGGACCCCA GAGGGCTCTC CCGGCAGGCG AGGCGCTCCG TGGACCTGGA GCTGGAGAGG 1200

TGCCGGCAGC AAGCAGGCTT CCCGGTGATC ACGGAGAAGG AGGAGCCCTG GGTCTTCAAC 1260

CCAGAAGCTG ACTCTGCAGC TGGGGAGCTG CTGGAGGCCT CTCAGGAGGA GTGGAGGCAG 1320

GTTGTAGATA TTCTGTGGAG TGACCCCATG GCTCAGGAGG GCTGCAGGGC CAACACTGTT 1380

CGAGGAGGAG GCTGCTATTT CGGGCCGAAT GTGACAAAAC AGCTGCTACA GAAATACAAC 1440

CTGCAATTCC TGATCCGCTC ACACGAGTGC AAACCCGAAG GCTATGAATT CTGCCACAGC 1500

CGCAAGGTGT TAACCGTCTT TTCCGCTTCC AACTACTATG CAGTTGGCAG TAACAGAGGG 1560

GCCTATGTCA AACTGGGGCC AGCCCTGGCC CCACACATCG TGCAGTATCA AGCTAACAAG 1620

GCGACCCACA TGCTGACCAT GAGGCAAAGG ATTAGCAGAG TAGAGGAGTC AGCTCTAAGA 1680

GCTCTGCGGG GAAAGTTATT TGCTCATTCC TCAGATCTTC TTGAGGAATT TAAGAAGCAT 1740

GATAATGGTA ACACTGGTTC AATCACCCTG AGTGACTGGG CAGCTGCTGT GGAGTCTGTG 1800

TTGCATCTAG GACTGCCATG GCGGATGCTG AGGCCACAGC TGGTGAGCAG CTCAACAGAT 1860

AACATGCTGG AGTACAAGTC CTGGCTGGAG GACTTGGCCA AAGAACAACT GAGTCACGAG 1920

AACATACAGT CGAGTTTGCT GGAAACACTG TATCGCAACC GATCTAACCT GGAGACCATT 1980

TTTAGGATCA TAGACAGTGA TCATTCAGGG TTCATCTCAC TGGACGAGTT CAGACAGACT 2040

TGGAAGCTGT TCAGCTCCCA TATGAAGATG GACATCACAG ACGACGGTAT CTGTGACCTT 2100

GCCCGGAGCA TTGACTTCAA CAAGGACGGC CACATTGACA TCAATGAGTT CCTGGAGGCC 2160

GTCCGCCTCG TGGAGCAGTC CTGCTCAGAG GGAGACGCCG CAGATTGTCC ACAAGCCACC 2220

AACACG 2226

Domain Profile

S: 4     llevfkkkrilhakyvlevlfeakkvlkqlpnishvstavskevtvvGdlhGklddlllv  63

         l+e+f+ k++lha+yvl++l+e++k l qlpni++vst+ s+e+tv+GdlhG+lddl+++

Q: 131   LVEAFRLKQQLHARYVLNLLHETRKHLVQLPNINRVSTCYSEEITVCGDLHGQLDDLIFI  190

         89**********************************************************

S: 64    lkknGlPsernpyvfnGdfvdrGkrglevllvllslflvfPnavylnrGnhedkvmnary  123

         ++knGlPs +++yvfnGdfvdrGk ++e+l+vl +++lv+P++ +lnrGnhed+++n+ry

Q: 191   FYKNGLPSPERAYVFNGDFVDRGKDSVEILMVLFAFMLVYPKEFHLNRGNHEDHMVNLRY  250

         ************************************************************

S: 124   GfekevlskykrkgkrilrileevyewlPlgsivdsrvlvvhGGlsestsldllksverk  183

         Gf+kev++kyk +gk+il+ l++v+ wlPl+++vd++vl++hGG+s++t+l+ll ++er+

Q: 251   GFTKEVMQKYKMHGKKILQRLQDVFCWLPLATLVDEKVLILHGGVSDTTDLELLSKLERH  310

         ************************************************************

S: 184   krksvllpPeessrdlgrldtdgep  208

         k +s l+  +  + +  + +++g++

Q: 311   KIVSTLRCKTRKENE-KQAEEKGKA  334

         ******987744333.233334433

Domain Sequence
(FASTA)

LVEAFRLKQQ LHARYVLNLL HETRKHLVQL PNINRVSTCY SEEITVCGDL HGQLDDLIFI 60

FYKNGLPSPE RAYVFNGDFV DRGKDSVEIL MVLFAFMLVY PKEFHLNRGN HEDHMVNLRY 120

GFTKEVMQKY KMHGKKILQR LQDVFCWLPL ATLVDEKVLI LHGGVSDTTD LELLSKLERH 180

KIVSTLRCKT RKENEKQAEE KGKA 204

Keyword

Calcium; Complete proteome; Hydrolase; Iron; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Callithrix jacchus"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Macaca mulatta"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryzias latipes"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005509	; F:calcium ion binding
GO:0005506	; F:iron ion binding
GO:0030145	; F:manganese ion binding
GO:0004721	; F:phosphoprotein phosphatase activity
GO:0050906	; P:detection of stimulus involved in sensory perception

KEGG

InterPros

IPR011992	; EF-hand-like_dom.
IPR018247	; EF_Hand_1_Ca_BS.
IPR018249	; EF_HAND_2.
IPR002048	; EF_hand_Ca-bd.
IPR000048	; IQ_motif_EF-hand-BS.
IPR004843	; Metallo_PEstase_dom.
IPR013235	; PPP_dom.
IPR012008	; Ser/Thr-Pase_EF-hand_contain.
IPR006186	; Ser/Thr-sp_prot-phosphatase.

Pfam

PF00149	; Metallophos; 1.
PF08321	; PPP5; 1.

SMARTs

SM00054	; EFh; 3.
SM00015	; IQ; 1.
SM00156	; PP2Ac; 1.

Prosites

PS00018	; EF_HAND_1; 2.
PS50222	; EF_HAND_2; 3.
PS00125	; SER_THR_PHOSPHATASE; 1.

Prints

PR00114

; STPHPHTASE.

Created Date

20-Feb-2013