EKS-MYL-00289

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-MYL-00289

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/IRE	480.0	1.9E-144	568	829	262

Status

Unreviewed

Ensembl Protein

ENSMLUP00000015259

UniProt Accession

G1PVB0;

Protein Name

Protein Synonyms/Alias

Gene Name

ERN1

Gene Synonyms/Alias

ERN1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMLUG00000016729	ENSMLUP00000015259	ENSMLUT00000016745

Organism

Myotis lucifugus

Functional Description

Protein Length

974

Protein Sequence
(FASTA)

VTWVLVLTQL LSRQGPLIFG SPSTVTLPET LLFVSTLDGS LHAVSKRTGS IKWTLKEDPV 60

LQVPTHVEEP AFLPDPNDGS LYTLGGKHSE GLTKLPFTIP ELVQASPCRS SDGILYMGKK 120

QDIWYVIDLL TGEKQQTLSS AFADSLCPST SLLYLGRTEY TITMYDTKTR ELRWNATYFD 180

YAASLPEDDV DYKMSHFVSN GDGLVVTVDS ESGDVLWIQN YASPVVAFYV WQREGLRKVM 240

HINVAVETLR YLTFMSGEVG RITKWKYPFP KETEAKSKLT PTLYVGKYST SLYASPSMVH 300

EGVAVVPRGS TLPLLEGPQT DGVTIGDKGE CVITPSTDLK LNPGLKGKNK LNYLRNYWLL 360

IGHHETPLSA STKMLERFPN NLPKHRENVI PADSEKKSFE DVIHLVDQTS GNAPSTVSQG 420

VEEKFAHAPA KPEAPVDSVL KDIATIVLST FLLIGWVAFI ITYPLSMHQQ QQLQHRQFQK 480

ELEKIQLLQQ QQLPFHAPRD MAQDAELLDS SGLYSESSGT SSPSTSPRAS NHSLHSSSSA 540

SRAGTSPCLE QDDEDEETSM VMVGKISFCP KDVLGHGAEG TIVYRGMFDS RDVAVKRILP 600

ECFSFADREV QLLRESDEHP NVIRYFCTEK DRQFQYIAIE LCAATLQEYV EQKDFAHLGL 660

EPITLLQQTT SGLAHLHSLN IVHRDLKPHN ILLSMPNAHG RIKAMISDFG LCKKLAVGRH 720

SFSRCSGVPG TEGWIAPEML SEDCKENPTY TVDIFSAGCV FYYVVSEGSH PFGKSLQRQA 780

NILLGAYSLD CLQPEKHEDV IARELIEKMI SMDPQKRPSA KHVLKHPFFW SLEKQLQFFQ 840

DVSDRIEKES LDGPIVKQLE RGGRAVVKMD WRENITVPLQ TDLRKFRTYK GGSVRDLLRA 900

MRNKKHHYRE LPVEVRETLG SLPDDFVRYF TSRFPHLLSH TYRAMELCSH ERLFQPYYFH 960

PPPEPQAPET ADAP 974

Nucleotide Sequence
(FASTA)

GTGACCTGGG TCCTAGTCCT GACTCAGCTG TTGTCCAGAC AGGGGCCCTT GATTTTTGGA 60

AGTCCCAGCA CAGTGACGCT TCCTGAAACC TTGCTGTTTG TGTCAACCCT GGATGGAAGT 120

TTGCACGCTG TCAGCAAGAG GACAGGCTCG ATCAAATGGA CTTTAAAAGA AGATCCAGTT 180

CTGCAGGTTC CAACGCACGT TGAAGAGCCT GCCTTCCTCC CGGATCCCAA CGATGGCAGT 240

CTGTATACAC TTGGGGGCAA GCACAGTGAA GGCCTAACGA AACTTCCTTT TACCATCCCG 300

GAGCTGGTCC AGGCATCGCC ATGCCGAAGT TCAGATGGGA TTCTCTACAT GGGTAAAAAG 360

CAGGACATTT GGTATGTCAT TGACCTTCTG ACCGGGGAGA AACAGCAGAC TTTGTCATCG 420

GCCTTTGCAG ATAGCCTCTG CCCTTCGACC TCTCTTCTGT ACCTTGGGCG CACAGAATAC 480

ACCATCACCA TGTACGACAC CAAAACCCGA GAGCTCCGGT GGAACGCCAC CTACTTCGAC 540

TACGCAGCCT CGCTGCCCGA GGACGACGTG GACTACAAGA TGTCCCATTT TGTGTCCAAT 600

GGCGATGGGC TGGTGGTGAC TGTGGACAGT GAGTCTGGCG ACGTCCTGTG GATCCAGAAC 660

TATGCCTCCC CTGTGGTGGC CTTTTACGTC TGGCAGCGGG AGGGGCTGCG GAAGGTGATG 720

CACATCAACG TCGCTGTGGA GACCCTGCGC TACCTGACCT TCATGTCCGG GGAGGTGGGG 780

CGCATCACCA AGTGGAAGTA CCCCTTCCCC AAGGAGACGG AGGCCAAGAG CAAGCTGACG 840

CCCACCCTGT ACGTTGGGAA ATACTCTACT AGCCTCTACG CCTCCCCCTC AATGGTCCAC 900

GAGGGGGTTG CTGTTGTGCC CCGAGGCAGC ACCCTTCCTT TGCTGGAAGG CCCCCAGACT 960

GACGGTGTCA CCATTGGGGA CAAAGGGGAG TGTGTGATCA CACCCAGCAC GGACCTGAAG 1020

CTTAACCCTG GGCTCAAAGG GAAGAACAAG CTCAACTACT TGAGGAACTA CTGGCTTCTG 1080

ATCGGACACC ATGAAACGCC GCTGTCTGCG TCTACCAAGA TGCTGGAGAG ATTCCCCAAC 1140

AATCTGCCCA AACACCGGGA AAATGTGATT CCTGCCGACT CTGAGAAAAA GAGCTTTGAG 1200

GACGTTATCC ACCTGGTTGA CCAGACTTCA GGGAATGCGC CCAGCACCGT TTCTCAGGGT 1260

GTGGAGGAGA AGTTCGCTCA CGCCCCCGCC AAGCCCGAGG CCCCCGTGGA CTCCGTGCTC 1320

AAGGACATCG CCACCATTGT CCTGAGCACC TTCCTGCTCA TCGGCTGGGT GGCCTTCATC 1380

ATCACCTACC CCCTGAGCAT GCATCAGCAG CAGCAGCTCC AGCACCGGCA GTTCCAGAAG 1440

GAACTGGAGA AAATCCAGCT CCTGCAACAG CAGCAGCTGC CCTTCCACGC ACCCAGGGAC 1500

ATGGCTCAGG ACGCCGAGCT CCTGGACTCG TCCGGCCTGT ACTCGGAGAG CTCGGGCACC 1560

AGCAGCCCCA GCACGTCCCC CCGAGCCTCC AACCACTCGC TGCACTCCAG CAGCTCTGCC 1620

TCCAGGGCCG GCACCAGCCC CTGCCTGGAG CAGGACGACG AGGATGAGGA AACCAGCATG 1680

GTGATGGTTG GGAAAATTTC CTTCTGTCCC AAGGACGTCC TGGGCCACGG AGCGGAGGGC 1740

ACAATTGTGT ACCGGGGCAT GTTCGACAGC CGCGACGTGG CGGTCAAGAG GATCCTCCCC 1800

GAGTGCTTCA GTTTCGCCGA CCGCGAGGTC CAGCTGCTGC GAGAGTCCGA CGAGCACCCG 1860

AACGTGATCC GTTACTTCTG CACAGAGAAG GACCGGCAGT TCCAGTACAT CGCCATCGAG 1920

CTGTGCGCGG CCACGCTGCA GGAGTACGTG GAGCAGAAGG ACTTTGCCCA CCTCGGCCTG 1980

GAGCCCATCA CCTTGCTGCA GCAGACCACC TCCGGCCTGG CCCACCTGCA CTCCCTCAAC 2040

ATCGTTCACA GAGACCTGAA GCCCCACAAC ATCCTCCTCT CCATGCCCAA TGCGCATGGC 2100

AGGATCAAGG CCATGATCTC CGACTTCGGC CTCTGCAAGA AGCTGGCAGT GGGCAGGCAC 2160

AGCTTCAGCC GCTGCTCGGG GGTGCCCGGC ACCGAAGGCT GGATCGCCCC GGAGATGCTG 2220

AGTGAGGACT GCAAGGAGAA CCCCACCTAC ACGGTGGACA TCTTCTCTGC GGGCTGCGTG 2280

TTCTACTACG TGGTTTCTGA GGGCAGCCAC CCTTTCGGCA AGTCCCTGCA GCGACAGGCC 2340

AACATCCTCC TGGGCGCCTA CAGCCTCGAC TGCTTACAGC CCGAGAAGCA CGAAGACGTC 2400

ATCGCCCGGG AGCTGATAGA GAAGATGATC TCCATGGACC CTCAGAAGCG CCCGTCAGCG 2460

AAGCACGTGC TGAAGCACCC GTTCTTCTGG AGCCTCGAGA AGCAGCTCCA GTTCTTCCAG 2520

GACGTGAGTG ACCGGATAGA AAAGGAGTCC CTGGACGGCC CGATTGTGAA GCAGCTGGAG 2580

AGAGGCGGGC GAGCCGTGGT GAAGATGGAC TGGAGGGAGA ACATCACCGT CCCCCTCCAG 2640

ACAGATCTGC GTAAATTCAG AACCTACAAG GGTGGCTCCG TCAGAGACCT CCTCCGAGCC 2700

ATGAGAAATA AGAAGCACCA CTACCGGGAG CTGCCCGTGG AGGTGCGGGA GACCCTGGGC 2760

TCCCTCCCCG ACGACTTCGT GCGCTACTTC ACGTCCCGCT TCCCCCACCT CCTCTCGCAC 2820

ACCTACCGGG CCATGGAGCT GTGCAGCCAC GAGCGGCTCT TCCAGCCCTA CTACTTCCAC 2880

CCGCCCCCCG AGCCGCAGGC CCCCGAGACT GCAGACGCCC CT 2922

Domain Profile

S: 1     fspkdvlGkGaeGtvvfrGsfegrevavkrllsefvdlakrevkllresdehpnviryfc  60

         f+pkdvlG+GaeGt+v+rG+f+ r+vavkr+l+e++++a+rev+llresdehpnviryfc

Q: 568   FCPKDVLGHGAEGTIVYRGMFDSRDVAVKRILPECFSFADREVQLLRESDEHPNVIRYFC  627

         79**********************************************************

S: 61    tekdrqfryialelcaaslqdyvedkdlelqkelepisllkqiasGlahlhslkivhrdl  120

         tekdrqf+yia+elcaa+lq+yve+kd++ + +lepi+ll+q++sGlahlhsl+ivhrdl

Q: 628   TEKDRQFQYIAIELCAATLQEYVEQKDFA-HLGLEPITLLQQTTSGLAHLHSLNIVHRDL  686

         *****************************.******************************

S: 121   kpqnilislpdakgklrvlisdfGlckkldvGkssfsrrsgvsGteGwiapelleeltke  180

         kp+nil+s+p+a+g+++++isdfGlckkl+vG++sfsr sgv+GteGwiape+l+e++ke

Q: 687   KPHNILLSMPNAHGRIKAMISDFGLCKKLAVGRHSFSRCSGVPGTEGWIAPEMLSEDCKE  746

         ************************************************************

S: 181   rltsavdifslGcvfyyvlskGkhpfGdslkrqanilsgelsldklkeekdeeviaedli  240

         ++t++vdifs+Gcvfyyv+s+G+hpfG+sl+rqanil g++sld+l++ek+e+via++li

Q: 747   NPTYTVDIFSAGCVFYYVVSEGSHPFGKSLQRQANILLGAYSLDCLQPEKHEDVIARELI  806

         ************************************************************

S: 241   skmidkdplkrpsakkvlkhplf  263

         +kmi++dp+krpsak+vlkhp+f

Q: 807   EKMISMDPQKRPSAKHVLKHPFF  829

         **********************9

Domain Sequence
(FASTA)

FCPKDVLGHG AEGTIVYRGM FDSRDVAVKR ILPECFSFAD REVQLLRESD EHPNVIRYFC 60

TEKDRQFQYI AIELCAATLQ EYVEQKDFAH LGLEPITLLQ QTTSGLAHLH SLNIVHRDLK 120

PHNILLSMPN AHGRIKAMIS DFGLCKKLAV GRHSFSRCSG VPGTEGWIAP EMLSEDCKEN 180

PTYTVDIFSA GCVFYYVVSE GSHPFGKSLQ RQANILLGAY SLDCLQPEKH EDVIARELIE 240

KMISMDPQKR PSAKHVLKHP FF 262

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0016891	; F:endoribonuclease activity, producing 5'-phosphomonoesters
GO:0004674	; F:protein serine/threonine kinase activity
GO:0006397	; P:mRNA processing

KEGG

InterPros

IPR010513	; KEN_RNase_activator.
IPR011009	; Kinase-like_dom.
IPR018391	; PQQ_beta_propeller_repeat.
IPR000719	; Prot_kinase_cat_dom.
IPR006567	; PUG-dom.
IPR011047	; Quinonprotein_ADH-like.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069	; Pkinase; 1.
PF06479	; Ribonuc_2-5A; 1.

SMARTs

SM00564	; PQQ; 5.
SM00580	; PUG; 1.

Prosites

PS51392	; KEN; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013