EKS-MYL-00169

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-MYL-00169

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/TLK	613.0	6.1E-185	410	688	279

Status

Unreviewed

Ensembl Protein

ENSMLUP00000015975

UniProt Accession

G1PX20;

Protein Name

Protein Synonyms/Alias

Gene Name

TLK1

Gene Synonyms/Alias

TLK1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMLUG00000017519	ENSMLUP00000015975	ENSMLUT00000017523

Organism

Myotis lucifugus

Functional Description

Protein Length

720

Protein Sequence
(FASTA)

GAMDELHSLD PRRQELLEAR FTGVATGSTG STGSCSVGAK ASTNNESSNH SFGSLGSLSD 60

KESETPEKKQ SESSRGRKRK AENQNESSQG KSIGGRGHKI SDYFEYQGGN GSSPVRGIPP 120

AIRSPQNSHS HSTPSSSVRP NSPSPIAVAF GDHPIIQPKQ LSFKITQTDL TMLKLAALES 180

NKNQDLEKKE GRIDDLLRAN CDLRRQIDEQ QKLLEKYKER LNKCISMSKK LLIEKSNQEK 240

LSSREKSMQD RLRLGHFTTV RHGASFTEQW TDGFAFQNLV KQQEWVNQQR EDIERQRKLL 300

AKRKPPTANN SQAPSTNSEP KQRKNKAVNG AENDPFVRPN LPQLLTLAEY HEQEEIFKLR 360

LGHLKKEEAE IQAELERLER VRNLHIRELK RINNEDNSQF KDHPTLNERY LLLHLLGRGG 420

FSEVYKAFDL YEQRYAAVKI HQLNKSWRDE KKENYYKHAC REYRIHKELD HPRIVKLYDY 480

FSLDTDTFCT VLEYCEGNDL DFYLKQHKLM SEKEARSIVM QIVNALRYLN EIKPPIIHYD 540

LKPGNILLVD GTACGEIKIT DFGLSKIMDD DSYGVDGMDL TSQGAGTYWY LPPECFVVGK 600

EPPKISNKVD VWSVGVIFFQ CLYGRKPFGH NQSQQDILQE NTILKATEVQ FPVKPVVSTE 660

AKAFIRRCLA YRKEDRFDVH QLANDPYLLP HMRRSNSSGN LHMAGLTASP TPPASSIMTY 720

Nucleotide Sequence
(FASTA)

GGTGCAATGG ATGAGCTTCA TAGTCTGGAT CCAAGAAGGC AAGAATTATT GGAAGCTAGA 60

TTTACAGGAG TTGCAACTGG GAGCACCGGG AGCACTGGGA GTTGCAGTGT GGGAGCTAAA 120

GCTTCAACAA ATAATGAAAG CTCTAATCAC AGTTTTGGAA GCTTGGGATC TTTAAGTGAC 180

AAAGAATCAG AGACACCAGA GAAGAAACAA TCTGAATCAT CCAGAGGAAG AAAGAGAAAA 240

GCAGAAAATC AGAATGAAAG TAGTCAGGGA AAAAGTATTG GGGGACGTGG CCACAAAATT 300

AGCGACTATT TTGAATACCA AGGTGGGAAT GGCTCAAGTC CAGTAAGAGG CATACCTCCT 360

GCAATCCGTT CTCCTCAGAA TTCACACTCA CATTCCACTC CTTCCTCATC TGTTCGACCT 420

AATAGCCCTT CTCCTATTGC AGTAGCTTTT GGGGACCACC CTATTATACA ACCAAAGCAG 480

TTATCCTTTA AAATTACTCA GACTGATCTC ACAATGCTGA AATTAGCAGC ATTAGAAAGT 540

AATAAAAACC AGGACCTGGA AAAGAAGGAA GGTCGTATAG ATGACTTGCT CAGGGCTAAC 600

TGTGATCTCA GACGGCAAAT AGATGAACAA CAAAAATTAC TTGAAAAATA CAAAGAACGA 660

TTAAATAAGT GCATATCAAT GAGCAAGAAA TTGCTTATTG AAAAGAGTAA CCAAGAAAAA 720

CTGTCAAGCC GGGAGAAGAG TATGCAAGAC AGATTACGCC TTGGACACTT CACAACAGTT 780

AGACATGGTG CTTCATTTAC TGAACAATGG ACAGATGGTT TTGCATTTCA GAATCTTGTG 840

AAGCAACAAG AATGGGTGAA TCAGCAAAGG GAAGATATTG AAAGGCAAAG GAAACTTCTA 900

GCCAAACGCA AACCTCCCAC AGCTAATAAT TCTCAGGCAC CCTCTACCAA CTCTGAACCA 960

AAACAGAGGA AAAATAAAGC AGTCAATGGC GCAGAAAATG ATCCCTTTGT TAGACCAAAC 1020

TTACCGCAAC TGTTGACTTT GGCAGAATAT CATGAACAGG AAGAAATTTT CAAACTTAGA 1080

CTAGGACATC TCAAAAAGGA AGAGGCAGAA ATTCAGGCAG AACTTGAACG TTTGGAAAGA 1140

GTAAGAAATC TGCACATTCG AGAGCTCAAA AGGATAAATA ATGAAGATAA TTCACAGTTC 1200

AAAGATCACC CAACGTTAAA TGAAAGATAT TTATTACTTC ATCTGCTTGG TAGAGGTGGC 1260

TTTAGTGAAG TGTATAAGGC TTTTGACCTT TATGAACAAA GATACGCTGC TGTGAAGATC 1320

CATCAGCTTA ATAAAAGCTG GAGGGATGAG AAAAAGGAAA ATTACTATAA ACATGCCTGC 1380

AGAGAGTATA GAATACACAA AGAACTGGAT CATCCCAGAA TAGTTAAACT CTATGATTAT 1440

TTCTCCTTGG ATACAGATAC GTTTTGTACA GTGTTAGAAT ACTGTGAAGG CAATGACTTG 1500

GATTTCTATC TGAAGCAACA TAAATTAATG TCGGAGAAAG AAGCTAGGTC TATTGTAATG 1560

CAAATTGTAA ATGCACTAAG ATATCTCAAT GAAATCAAAC CCCCTATTAT ACATTATGAT 1620

CTTAAGCCAG GAAACATCCT TCTGGTGGAT GGAACAGCTT GTGGAGAAAT CAAAATCACT 1680

GATTTTGGTC TGTCCAAGAT CATGGATGAC GATAGCTATG GTGTAGATGG AATGGACCTA 1740

ACTTCCCAAG GGGCAGGCAC TTACTGGTAT TTACCTCCTG AGTGTTTTGT AGTTGGAAAA 1800

GAACCACCAA AAATTTCCAA CAAGGTTGAT GTGTGGTCAG TTGGAGTCAT TTTCTTTCAG 1860

TGTCTTTATG GCAGAAAGCC ATTTGGTCAC AATCAATCTC AACAAGACAT TCTTCAAGAA 1920

AATACAATAT TAAAAGCCAC AGAAGTTCAG TTCCCTGTAA AACCGGTTGT AAGCACTGAA 1980

GCCAAGGCCT TTATACGACG CTGTTTGGCA TACCGAAAAG AAGATCGATT TGATGTGCAC 2040

CAACTGGCAA ATGACCCGTA CCTTCTCCCA CACATGAGAA GATCAAACTC TTCAGGAAAC 2100

TTACACATGG CTGGGCTGAC AGCATCCCCC ACACCCCCTG CTTCAAGCAT AATGACTTAC 2160

TGA 2163

Domain Profile

S: 1     ylllkllgkggfsevykafdlkeqryvavkihqlnkdwkdekkenyvkhalreyrihkel  60

         ylll+llg+ggfsevykafdl+eqry+avkihqlnk+w+dekkeny+kha+reyrihkel

Q: 410   YLLLHLLGRGGFSEVYKAFDLYEQRYAAVKIHQLNKSWRDEKKENYYKHACREYRIHKEL  469

         9***********************************************************

S: 61    dhprivklydllsldtdsfctvleyvegndldfylkqhkllsekearsiimqivsalkyl  120

         dhprivklyd++sldtd+fctvley+egndldfylkqhkl+sekearsi+mqiv+al+yl

Q: 470   DHPRIVKLYDYFSLDTDTFCTVLEYCEGNDLDFYLKQHKLMSEKEARSIVMQIVNALRYL  529

         ************************************************************

S: 121   neikppiihydlkpgnillvegtacgeikitdfglskimdddsydsddgleltsqgagty  180

         neikppiihydlkpgnillv+gtacgeikitdfglskimdddsy++d g++ltsqgagty

Q: 530   NEIKPPIIHYDLKPGNILLVDGTACGEIKITDFGLSKIMDDDSYGVD-GMDLTSQGAGTY  588

         *********************************************99.************

S: 181   wylppecfvvgkeppkisnkvdvwsvgvifyqclygkkpfghnqsqqdileentilkate  240

         wylppecfvvgkeppkisnkvdvwsvgvif+qclyg+kpfghnqsqqdil+entilkate

Q: 589   WYLPPECFVVGKEPPKISNKVDVWSVGVIFFQCLYGRKPFGHNQSQQDILQENTILKATE  648

         ************************************************************

S: 241   vqfpskpvvsseakafirrclayrkedridvqqlakdeyl  280

         vqfp+kpvvs+eakafirrclayrkedr+dv+qla+d+yl

Q: 649   VQFPVKPVVSTEAKAFIRRCLAYRKEDRFDVHQLANDPYL  688

         **************************************97

Domain Sequence
(FASTA)

YLLLHLLGRG GFSEVYKAFD LYEQRYAAVK IHQLNKSWRD EKKENYYKHA CREYRIHKEL 60

DHPRIVKLYD YFSLDTDTFC TVLEYCEGND LDFYLKQHKL MSEKEARSIV MQIVNALRYL 120

NEIKPPIIHY DLKPGNILLV DGTACGEIKI TDFGLSKIMD DDSYGVDGMD LTSQGAGTYW 180

YLPPECFVVG KEPPKISNKV DVWSVGVIFF QCLYGRKPFG HNQSQQDILQ ENTILKATEV 240

QFPVKPVVST EAKAFIRRCL AYRKEDRFDV HQLANDPYL 279

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013