EKS-MYL-00071

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-MYL-00071

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDK	352.9	1.2E-105	107	391	285

Status

Unreviewed

Ensembl Protein

ENSMLUP00000016020

UniProt Accession

G1PX63;

Protein Name

Protein Synonyms/Alias

Gene Name

CDK15

Gene Synonyms/Alias

CDK15;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMLUG00000017566	ENSMLUP00000016020	ENSMLUT00000017571

Organism

Myotis lucifugus

Functional Description

Protein Length

439

Protein Sequence
(FASTA)

MGQELCAKTL RPGCSCHRCW EGGDARSCQR RAPERTRTEA AIQLTDLKEA SRSMTSFHPR 60

GRQAAHARKC KSKRPRSNSE SFQEEDLRQG FQWPTKSLLP FGAASSYLNL EKLGEGSYAT 120

VYKGISRINR QLVALKVISM NEEEGVPFTA IREASLLKGL KHANIVLLHD IIHTKETLTF 180

VFEYMHTDLA QYMSQHPGGL HPHNVRLFMF QLLRGLAYIH HQHVLHRDLK PQNILISHLG 240

ELKLADFGLA RAKSIPSQTY SSEVVTLWYR PPDALLGATE YSSELDIWGA GCIFIEMFQG 300

QPLFPGVTSI FEQLEKIWEV LGVPTEDTWP GVSKLPNYNP EWFPLLKPQS LQNVWNRLGR 360

IPEAEDLASQ MLKGFPRDRV SAQEALVHDY FSSLPSQLHQ LPDEESLFTV SGVGLKPEMY 420

DLLASYRKGH RTGHFSKCW 439

Nucleotide Sequence
(FASTA)

ATGGGCCAGG AGCTGTGTGC GAAGACTCTC CGGCCCGGCT GCAGCTGCCA TCGCTGCTGG 60

GAGGGAGGCG ATGCACGCAG CTGTCAGAGG AGAGCGCCCG AGAGGACCAG GACCGAGGCT 120

GCCATCCAGC TAACAGACCT CAAAGAAGCA TCACGTTCCA TGACTTCATT TCACCCCAGG 180

GGACGTCAGG CTGCCCATGC CCGGAAGTGC AAGAGTAAAA GGCCACGCAG TAACAGTGAG 240

TCTTTTCAGG AAGAGGATCT GAGGCAGGGC TTTCAGTGGC CCACGAAGAG CCTCCTCCCT 300

TTTGGGGCAG CCTCATCCTA CTTGAACTTG GAGAAGCTGG GTGAAGGTTC CTATGCTACG 360

GTTTACAAGG GGATTAGCAG AATAAACAGA CAACTAGTGG CTTTAAAAGT CATCAGCATG 420

AATGAAGAGG AAGGAGTCCC ATTTACAGCC ATCCGAGAAG CTTCGCTTTT GAAGGGTCTG 480

AAACATGCCA ATATTGTGCT CCTGCATGAC ATAATCCACA CCAAAGAGAC ACTGACGTTC 540

GTTTTCGAAT ACATGCACAC GGACCTGGCC CAGTACATGT CCCAGCACCC GGGCGGACTG 600

CACCCTCACA ACGTCCGGCT TTTCATGTTT CAACTTTTGC GGGGCCTGGC GTACATCCAC 660

CACCAACACG TTCTTCACAG GGACCTGAAA CCTCAGAACA TTCTCATCAG TCACCTGGGA 720

GAGCTCAAGC TGGCTGACTT TGGTCTTGCT CGGGCCAAGT CCATTCCCAG CCAGACCTAC 780

TCTTCAGAAG TTGTGACCCT CTGGTACCGC CCTCCTGATG CTCTGCTGGG AGCCACTGAA 840

TATTCCTCTG AACTGGACAT ATGGGGTGCC GGCTGCATCT TTATTGAAAT GTTCCAGGGT 900

CAACCTTTGT TTCCTGGGGT TACCAGCATC TTTGAACAGC TGGAGAAGAT CTGGGAGGTG 960

TTGGGAGTCC CTACCGAGGA CACCTGGCCT GGAGTTTCCA AACTACCTAA CTACAATCCA 1020

GAATGGTTCC CACTGCTTAA ACCTCAGAGC CTTCAGAACG TCTGGAACAG GTTGGGCAGG 1080

ATTCCGGAAG CCGAAGACCT GGCCTCGCAA ATGCTGAAAG GCTTCCCTAG AGACCGCGTC 1140

TCCGCCCAGG AGGCCCTGGT CCATGATTAT TTCAGCTCCC TGCCATCTCA GCTGCACCAG 1200

CTTCCCGACG AGGAGTCTTT GTTTACAGTT TCAGGAGTGG GGCTGAAGCC AGAAATGTAT 1260

GACCTTTTGG CTTCCTACCG GAAAGGTCAC CGCACAGGCC ACTTTAGCAA ATGCTGGTGA 1320

Domain Profile

S: 1     yeklekigeGtygkvykakdketgevvAlKkirlekekegvpitalrEisllkelkhkni  60

         y +lek+geG+y++vyk+ ++ + ++vAlK i +++e egvp+ta+rE sllk lkh+ni

Q: 107   YLNLEKLGEGSYATVYKGISRINRQLVALKVISMNEE-EGVPFTAIREASLLKGLKHANI  165

         6789****************************99887.9*********************

S: 61    vkLlevvakdkkklyLvfefleqdLkkllkkkkkkklsleevkslllqlleglaylHsnk  120

         v L+++++ +k++l++vfe++++dL++++++++  +l++++v+ +++qll+glay+H+++

Q: 166   VLLHDIIH-TKETLTFVFEYMHTDLAQYMSQHPG-GLHPHNVRLFMFQLLRGLAYIHHQH  223

         ********.99***********************.*************************

S: 121   ilHRDlKpqNlLiskegklklaDfGlarafssplktytkevvTlwYraPelLlgakeYst  180

         +lHRDlKpqN+Lis+ g+lklaDfGlara s p++ty++evvTlwYr+P+ Llga+eYs+

Q: 224   VLHRDLKPQNILISHLGELKLADFGLARAKSIPSQTYSSEVVTLWYRPPDALLGATEYSS  283

         ************************************************************

S: 181   avDiWsvgcilaelltrkplfqgkse.idqlerifkllgtpsekvwpevsklpeyk.ksf  238

         ++DiW++gci+ e+++ +plf+g +   +qle+i+++lg p+e++wp+vsklp+y+ + f

Q: 284   ELDIWGAGCIFIEMFQGQPLFPGVTSiFEQLEKIWEVLGVPTEDTWPGVSKLPNYNpEWF  343

         ***********************98857****************************8899

S: 239   pkkkkkklkekvkklk..ekaldllekllaldpkkRisakealqhkyf  284

         p  k+++l++++++l    +a dl +++l+  p++R+sa+eal h+yf

Q: 344   PLLKPQSLQNVWNRLGriPEAEDLASQMLKGFPRDRVSAQEALVHDYF  391

         999**********9996667***************************9

Domain Sequence
(FASTA)

YLNLEKLGEG SYATVYKGIS RINRQLVALK VISMNEEEGV PFTAIREASL LKGLKHANIV 60

LLHDIIHTKE TLTFVFEYMH TDLAQYMSQH PGGLHPHNVR LFMFQLLRGL AYIHHQHVLH 120

RDLKPQNILI SHLGELKLAD FGLARAKSIP SQTYSSEVVT LWYRPPDALL GATEYSSELD 180

IWGAGCIFIE MFQGQPLFPG VTSIFEQLEK IWEVLGVPTE DTWPGVSKLP NYNPEWFPLL 240

KPQSLQNVWN RLGRIPEAED LASQMLKGFP RDRVSAQEAL VHDYF 285

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013