EPS-MYL-00056

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-MYL-00056

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
DSP/PTEN	268.0	5.4E-80	133	307	175

Status

Unreviewed

Ensembl Protein

ENSMLUP00000017558

UniProt Accession

G1Q1H5;

Protein Name

Protein Synonyms/Alias

Gene Name

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMLUG00000029270	ENSMLUP00000017558	ENSMLUT00000030189

Organism

Myotis lucifugus

Functional Description

Protein Length

450

Protein Sequence
(FASTA)

FLFRIFGILL VFVDVSLVIA DLLTTDQTMA YRLISLLIGL YFFMDILLQV FVEGILSYFS 60

DILNSMDAAI IVVTLIIDFN DIFYDYEIFK DIPRLVILLR SLRLIILMRI FHLAYEERQL 120

EKLTRRMVSG NKRRYKKDGF DLDLTYVTER IIAMSFPSSG KESFYRNPIQ EVVRFLDTKH 180

RNHYQVYNLC SERSYDPKYF HYRVHRIMID DHNVPSLSEM VEFSKEAQNW MAQDDKNIIV 240

IHCKGGKGRT GTMACACLIA CEIFTTAEES LYYFGERRTD KTTSSKFQGV ETPSQNRYVG 300

YFEDVKNIYN LTLPPRKILR IKKFVIYSIH GVGKGNGDDL KVKIIMRQKI AFFCSASKNC 360

RVVHDIERDR VIIHLCNCPL LYDDVKVQFL SSSDLPKYYD NCPFYFWFHT SFIENNRLYL 420

SRNELDNPHK PKAWKIYHPE FAVEIYFDDV 450

Nucleotide Sequence
(FASTA)

TTTTTATTCA GAATTTTTGG AATTTTGCTG GTCTTTGTGG ATGTGTCCCT CGTCATTGCA 60

GACCTACTTA CCACTGATCA AACAATGGCA TATCGTTTAA TTTCTTTATT GATTGGTTTA 120

TATTTTTTCA TGGATATTCT TCTTCAAGTA TTTGTAGAAG GGATACTATC ATATTTTTCT 180

GATATACTTA ATTCCATGGA TGCTGCCATT ATTGTAGTGA CTCTAATAAT TGATTTCAAT 240

GATATTTTTT ATGACTATGA GATTTTTAAA GATATTCCCA GATTGGTAAT TCTCCTTCGG 300

TCTCTACGCC TTATCATTCT GATGAGAATT TTTCATTTGG CTTACGAAGA AAGACAGCTT 360

GAAAAGTTGA CCAGAAGGAT GGTTTCAGGA AACAAACGAC GATACAAGAA AGATGGATTT 420

GACTTAGACC TCACTTACGT TACTGAACGT ATTATTGCCA TGTCATTCCC ATCTTCTGGA 480

AAGGAGTCTT TCTATAGGAA TCCAATTCAG GAAGTTGTGC GGTTCCTGGA TACCAAGCAT 540

CGAAACCACT ATCAAGTCTA CAATCTTTGC AGTGAAAGAT CTTATGATCC TAAGTACTTC 600

CATTATAGGG TCCATCGAAT CATGATTGAT GATCATAATG TCCCCTCTCT GAGTGAGATG 660

GTGGAATTTT CCAAAGAAGC ACAGAATTGG ATGGCTCAAG ATGACAAAAA CATCATAGTG 720

ATTCACTGTA AGGGAGGCAA AGGAAGAACT GGAACTATGG CTTGTGCGTG CCTTATTGCC 780

TGTGAAATAT TTACAACTGC AGAGGAGAGC CTTTATTATT TTGGAGAACG ACGAACAGAT 840

AAAACCACCA GCAGTAAATT TCAGGGAGTA GAAACTCCTT CTCAGAATAG GTATGTTGGA 900

TATTTTGAAG ATGTGAAAAA TATTTATAAC TTGACTCTCC CTCCAAGAAA AATACTTAGG 960

ATAAAAAAAT TTGTTATTTA TTCAATTCAT GGTGTTGGAA AAGGCAACGG TGATGATCTA 1020

AAAGTGAAAA TAATAATGCG TCAAAAGATT GCCTTTTTCT GTTCTGCTTC CAAAAACTGT 1080

AGGGTAGTTC ATGATATTGA AAGGGACAGA GTAATAATTC ATCTATGCAA CTGTCCACTT 1140

CTGTATGATG ATGTAAAAGT GCAATTTCTG TCTTCTTCAG ATCTTCCTAA ATACTATGAC 1200

AACTGCCCCT TTTACTTTTG GTTCCACACA TCCTTTATAG AAAATAACAG GCTTTATCTT 1260

TCAAGAAATG AATTGGATAA TCCCCATAAA CCAAAAGCAT GGAAAATTTA TCATCCAGAG 1320

TTTGCAGTTG AAATTTATTT TGATGATGTT 1350

Domain Profile

S: 1     rrltedgfdldltyvteriiavsfPaeareevyrnnlrevvrlldskhrnkyklynlcse  60

         rr+++dgfdldltyvteriia+sfP++++e++yrn+++evvr+ld khrn+y++ynlcse

Q: 133   RRYKKDGFDLDLTYVTERIIAMSFPSSGKESFYRNPIQEVVRFLDTKHRNHYQVYNLCSE  192

         79**********************************************************

S: 61    rrydltklnakvaefgiedlnaPaleklvsickeldeWlseddenvvvlhckggkgrlGv  120

         r yd++ ++ +v++++i+d+n+P+l ++v ++ke ++W+++dd+n++v+hckggkgr+G+

Q: 193   RSYDPKYFHYRVHRIMIDDHNVPSLSEMVEFSKEAQNWMAQDDKNIIVIHCKGGKGRTGT  252

         ************************************************************

S: 121   ivcayllaseisakadealdtfgerr...tredkvagvkqPsqrryvsyfsqllk  172

         + ca l+a ei+++a+e+l++fgerr   t++ k++gv++Psq+ryv yf  +++

Q: 253   MACACLIACEIFTTAEESLYYFGERRtdkTTSSKFQGVETPSQNRYVGYFEDVKN  307

         *************************9888899******************99986

Domain Sequence
(FASTA)

RRYKKDGFDL DLTYVTERII AMSFPSSGKE SFYRNPIQEV VRFLDTKHRN HYQVYNLCSE 60

RSYDPKYFHY RVHRIMIDDH NVPSLSEMVE FSKEAQNWMA QDDKNIIVIH CKGGKGRTGT 120

MACACLIACE IFTTAEESLY YFGERRTDKT TSSKFQGVET PSQNRYVGYF EDVKN 175

Keyword

Complete proteome; Hydrolase; Ion transport; Ionic channel; Membrane; Protein phosphatase; Reference proteome; Transmembrane; Transport.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0016021	; C:integral to membrane
GO:0005216	; F:ion channel activity
GO:0004725	; F:protein tyrosine phosphatase activity
GO:0035335	; P:peptidyl-tyrosine dephosphorylation

KEGG

InterPros

IPR008973	; C2_Ca/lipid-bd_dom_CaLB.
IPR005821	; Ion_trans_dom.
IPR014019	; Phosphatase_tensin-typ.
IPR014020	; Tensin_phosphatase_C2-dom.
IPR016130	; Tyr_Pase_AS.
IPR000242	; Tyr_Pase_rcpt/non-rcpt.

Pfam

PF00520	; Ion_trans; 1.
PF10409	; PTEN_C2; 1.
PF00102	; Y_phosphatase; 1.

SMARTs

Prosites

PS51182	; C2_TENSIN; 1.
PS51181	; PPASE_TENSIN; 1.
PS00383	; TYR_PHOSPHATASE_1; 1.

Prints

Created Date

20-Feb-2013