EPS-MYL-00009

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-MYL-00009

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
DSP/aDSP	152.2	8.6E-45	134	279	146

Status

Unreviewed

Ensembl Protein

ENSMLUP00000019870

UniProt Accession

G1Q837;

Protein Name

Protein Synonyms/Alias

Gene Name

DUSP27

Gene Synonyms/Alias

DUSP27;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMLUG00000030263	ENSMLUP00000019870	ENSMLUT00000026044

Organism

Myotis lucifugus

Functional Description

Protein Length

902

Protein Sequence
(FASTA)

MATRGDPEEE QVVPSEEDEA DVRAVQARYL LRSPSPSQYS VVSEAETESI FMEPIHLSSA 60

VAAKRIIREE LGPRGVRAEA ECPGMLESAE QLLMEDLYHR VREKMDDTSL YNTPCVLDLQ 120

RALVQDRQEA PWNEVDEVWP NVFIAEKSVA VNKGRLKRLG ITHILNAAHG TGVYTGPEFY 180

AGLDIQYLGV EVDDFPEVDI SRHFRKAAEF LDEALLTYRG KVLVSSEMGI SRSAVLVVAY 240

LMIFHHMAVL EALMTVRRKR PICPNDGFLR QLRELNEKLM EERDEDDSGE GGAHGAEEGE 300

DTGSTIGARV QDLTVEEQDD TTSRLSGSSL GAASQASKPL TLIDEEEEEK LYEQWKKEQG 360

LPTGKAPQGG DGRCSAPSAQ GGDEPEDEDV EGIIREWQRR NERYQAEGHR KWGQEEEVEE 420

EGDVGSFKGR RRRCTRSETS TSESMSSHDI RVLKQQLEMS SQSRRGRQRS DSVSTDSSWD 480

VWNQRLLEIE KEASRRYQSR SEREEVGASS EAGSRVREED EESVLSEASS FYNFCSRNKD 540

KLTALERWKI KRIQFGFHKR DSEAGDSCSE PGAEEAEREK KGASDVNLTA YQAWKLKHQK 600

KVGSENKEEV VELSKDEASA SAKKRQRRLE LLERSRQTLE ESQSMGSWEA DGSASRSIPL 660

SAFLVRSPLR LVLIGDTASV LSTLSLSSHP SQAPLHALPS LPVGPGDTVC IASIQNWIAN 720

VVSETLAQKQ NEMLLLSRSP SAASAKVGPA ASGPGDDQVS MLSAQSASSL GLPPRGQARP 780

GSDTQSLPSC HSTPSSRAEG TGSTGRGTSK PVYSLFADHV NLKELGQKEK EMQMELREKM 840

SEYKMEKLAS DHKRSNLFKK KKVREDEDGD VGERDEDADS AIGSFRYSSR GGSQKPETDT 900

NT 902

Nucleotide Sequence
(FASTA)

ATGGCGACCC GTGGGGACCC CGAGGAGGAG CAGGTCGTCC CAAGTGAAGA GGACGAAGCG 60

GACGTGAGGG CCGTGCAGGC CCGGTACCTC CTGCGGAGCC CCTCGCCCAG CCAGTACTCG 120

GTGGTCTCGG AGGCGGAGAC GGAGAGCATT TTCATGGAGC CCATTCACCT CTCCTCAGCC 180

GTGGCTGCCA AGCGCATCAT CAGGGAAGAA CTCGGGCCGC GGGGCGTCAG GGCTGAGGCA 240

GAGTGTCCGG GCATGCTGGA GTCCGCTGAG CAGCTGCTGA TGGAGGACCT GTACCACCGC 300

GTCCGGGAGA AGATGGACGA CACCAGCCTG TACAACACCC CCTGCGTCCT GGACCTGCAG 360

CGGGCCTTGG TCCAGGACCG CCAGGAGGCC CCCTGGAACG AGGTGGATGA GGTCTGGCCC 420

AACGTCTTCA TAGCAGAGAA GAGTGTGGCT GTGAACAAGG GCCGGCTGAA GAGGCTGGGG 480

ATTACCCACA TCCTGAACGC CGCCCACGGC ACCGGCGTCT ACACGGGGCC CGAGTTCTAC 540

GCCGGCCTGG ACATCCAGTA CCTGGGGGTG GAGGTGGACG ACTTCCCCGA GGTGGACATC 600

TCCCGGCACT TCCGGAAGGC CGCCGAGTTC CTGGACGAGG CCCTGCTCAC CTATCGAGGG 660

AAAGTGCTGG TCAGCAGCGA GATGGGCATC AGCCGGTCGG CGGTGCTGGT GGTGGCCTAC 720

CTCATGATCT TCCACCACAT GGCCGTCCTG GAGGCCCTGA TGACCGTGCG GAGGAAGCGG 780

CCCATCTGCC CCAACGACGG CTTCCTCAGG CAGCTCCGGG AGCTCAACGA GAAGCTGATG 840

GAAGAGAGAG ACGAGGACGA CAGCGGGGAG GGGGGCGCAC ATGGGGCCGA GGAGGGTGAG 900

GACACGGGGA GCACCATCGG GGCCAGGGTG CAGGACCTCA CGGTGGAGGA GCAGGACGAC 960

ACCACCAGCC GCCTGAGTGG CTCCTCCTTG GGGGCGGCCA GCCAGGCCTC CAAGCCCCTC 1020

ACCCTCATCG ACGAAGAGGA GGAGGAGAAG CTCTACGAGC AGTGGAAGAA GGAGCAGGGC 1080

CTCCCCACCG GCAAGGCCCC GCAGGGTGGG GATGGCAGGT GCTCCGCGCC CTCTGCCCAG 1140

GGCGGGGACG AGCCTGAGGA TGAGGATGTG GAGGGGATCA TCCGGGAGTG GCAGCGCCGA 1200

AACGAGAGGT ACCAGGCAGA AGGGCACCGG AAGTGGGGGC AGGAGGAGGA GGTGGAGGAG 1260

GAGGGTGATG TCGGCTCCTT CAAGGGGAGA AGGCGCCGGT GCACCCGGAG TGAGACCAGC 1320

ACCTCGGAGA GCATGAGCAG CCATGACATT CGGGTCCTGA AGCAGCAACT GGAGATGAGC 1380

AGCCAGAGCC GGCGAGGGAG GCAGCGCTCC GACTCCGTGT CCACGGACAG CTCCTGGGAC 1440

GTGTGGAACC AGAGGCTGCT GGAGATTGAG AAGGAAGCTT CCCGGAGGTA CCAGTCCAGG 1500

AGCGAGAGAG AGGAGGTGGG CGCAAGCTCA GAGGCGGGGA GCAGGGTCCG GGAGGAGGAT 1560

GAGGAGAGTG TGCTGTCGGA GGCCAGCTCC TTCTATAACT TCTGCAGCAG GAACAAGGAC 1620

AAACTCACTG CCCTCGAAAG GTGGAAGATC AAGAGAATCC AATTTGGGTT TCACAAGAGG 1680

GACTCGGAGG CAGGAGACAG CTGCAGCGAG CCAGGCGCAG AGGAGGCCGA GCGGGAGAAG 1740

AAAGGCGCCT CCGACGTCAA CCTGACAGCC TACCAGGCCT GGAAGCTGAA ACACCAGAAG 1800

AAAGTGGGCA GTGAGAACAA GGAGGAGGTG GTGGAGCTCA GCAAGGACGA GGCCTCAGCC 1860

TCGGCCAAGA AGAGGCAGCG GAGGCTGGAG CTGCTGGAGA GAAGCAGGCA GACGCTGGAG 1920

GAGAGCCAGT CCATGGGCAG CTGGGAGGCT GACGGCTCGG CCAGCAGGAG CATCCCCCTG 1980

TCTGCCTTTC TGGTCCGCAG CCCCCTTCGG TTAGTACTGA TTGGGGACAC AGCCTCAGTA 2040

CTCAGCACCC TGAGCCTCAG CTCCCACCCA TCTCAGGCCC CCCTCCACGC GCTGCCTAGC 2100

CTCCCCGTGG GGCCTGGAGA CACCGTTTGC ATTGCCAGTA TCCAGAACTG GATCGCCAAC 2160

GTGGTCAGCG AGACTCTCGC CCAGAAGCAA AACGAAATGC TGCTGCTGTC ACGCTCCCCA 2220

TCCGCGGCAA GTGCCAAGGT GGGGCCGGCG GCCAGCGGCC CGGGGGATGA CCAGGTCTCC 2280

ATGCTCAGCG CACAGAGCGC CTCCTCCCTG GGCCTTCCGC CTCGAGGGCA GGCAAGACCC 2340

GGTTCCGACA CGCAGTCCCT GCCGTCCTGC CACAGCACGC CGAGCTCCAG GGCCGAAGGC 2400

ACGGGGAGCA CTGGGAGGGG GACCAGCAAG CCCGTCTACA GCCTCTTTGC TGACCACGTC 2460

AACCTGAAGG AGCTGGGCCA GAAGGAGAAG GAGATGCAGA TGGAGCTGAG GGAGAAGATG 2520

TCTGAGTACA AGATGGAGAA GCTGGCCTCC GACCACAAAC GCAGCAACCT TTTCAAGAAG 2580

AAGAAGGTCA GGGAAGATGA GGACGGGGAC GTGGGCGAGA GAGACGAGGA CGCCGACAGC 2640

GCCATCGGCA GCTTCCGGTA TTCTTCCCGC GGCGGCTCCC AGAAGCCTGA AACGGACACC 2700

AACACC 2706

Domain Profile

S: 1     evteilpglylgdqataldrreLsklgitvvinaslsvikvqviPeylikkgityknipv  60

         ev+e++p+++++++ +a+++  L++lgit+++na++++    ++Pe++   +i+y++++v

Q: 134   EVDEVWPNVFIAEKSVAVNKGRLKRLGITHILNAAHGTGV-YTGPEFYAGLDIQYLGVEV  192

         69**********************************8765.79*****************

S: 61    dDsdvtdllqyfdeaaefidea.kekggkvlvHCaaGvsRSatlvlaYLmkveglslsdA  119

         dD ++ d++++f++aaef+dea  + +gkvlv +++G+sRSa+lv+aYLm+++++++ +A

Q: 193   DDFPEVDISRHFRKAAEFLDEAlLTYRGKVLVSSEMGISRSAVLVVAYLMIFHHMAVLEA  252

         **********************8999**********************************

S: 120   ieavkrkrpsiepnegfleQLlelekkl  147

         +++v+rkr  i+pn+gfl+QL+el++kl

Q: 253   LMTVRRKR-PICPNDGFLRQLRELNEKL  279

         ********.689************9987

Domain Sequence
(FASTA)

EVDEVWPNVF IAEKSVAVNK GRLKRLGITH ILNAAHGTGV YTGPEFYAGL DIQYLGVEVD 60

DFPEVDISRH FRKAAEFLDE ALLTYRGKVL VSSEMGISRS AVLVVAYLMI FHHMAVLEAL 120

MTVRRKRPIC PNDGFLRQLR ELNEKL 146

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0008138	; F:protein tyrosine/serine/threonine phosphatase activity
GO:0006470	; P:protein dephosphorylation

KEGG

InterPros

IPR020417	; Atypical_DUSP.
IPR020405	; Atypical_DUSP_famA.
IPR000340	; Dual-sp_phosphatase_cat-dom.
IPR020422	; Dual-sp_phosphatase_subgr_cat.
IPR024950	; DUSP.
IPR000387	; Tyr/Dual-specificity_Pase.

Pfam

PF00782

; DSPc; 1.

SMARTs

SM00195

; DSPc; 1.

Prosites

PS50056	; TYR_PHOSPHATASE_2; 1.
PS50054	; TYR_PHOSPHATASE_DUAL; 1.

Prints

PR01908	; ADSPHPHTASE.
PR01909	; ADSPHPHTASEA.

Created Date

20-Feb-2013