EKS-MAM-00217

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-MAM-00217

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/NKF2	614.1	1.2E-184	156	512	357

Status

Unreviewed

Ensembl Protein

ENSMMUP00000000169

UniProt Accession

F7H674;

Protein Name

Protein Synonyms/Alias

Serine/threonine-protein kinase PINK1, mitochondrial;

Gene Name

PINK1

Gene Synonyms/Alias

PINK1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMMUG00000000126	ENSMMUP00000000169	ENSMMUT00000000181

Organism

Macaca mulatta

Functional Description

Protein Length

581

Protein Sequence
(FASTA)

MAVRQALGRG LQLGRELLLR FTGKPGRAYG LGRPGPAAGC VRGERPGWAA GPGAEPRRIG 60

LGLPNRLRFF RQSVAGLAAR LQRQFLVRAW GCAGPCGRAV FLAFGLGLGL IEEKQAESRR 120

AVSACQEIQA IFTQKSKPGP DPLDTRRWQG FRLEEYLIGQ SIGKGCSAAV YEATMPALPQ 180

NLEVTKSTGS LPGRGPGTSA PGEEQEQALG APAFPLAIKM MWNISAGSSS EAILNTMSQE 240

LVPASRVALA GEYGAVTYRK SKRGPKQLAP HPNIIRVLRA FTSSVPLLPG ALVDYPDVLP 300

PRLHPEGLGH GRTLFLVMKN YPCTLRQYLR ANTPSPRLAT MMMLQLLEGV DHLVQQGIAH 360

RDLKSDNILV ELDPDGCPWL VIADFGCCLA DESIGLQLPF SSWYVDRGGN GCLMAPEVST 420

ARPGPRAVID YSKADAWAVG AIAYEIFGLV NPFYSQGKAH LESRSYQEAQ LPALPESVPP 480

DVRQLVRALL QREASKRPSA RVAANVLHLS LWGEQILALK NLKLDKMVGW LLQQSAATLL 540

ANRLTEKCCV ETKMKMLFLA NLECETLCQA ALLLCSWRAA L 581

Nucleotide Sequence
(FASTA)

ATGGCGGTGC GACAGGCGCT AGGCCGCGGC CTGCAGCTGG GTCGAGAGCT GCTGCTGCGC 60

TTCACCGGCA AGCCGGGCCG GGCCTACGGC TTGGGGCGGC CGGGCCCGGC GGCGGGCTGT 120

GTGCGCGGGG AGCGTCCGGG CTGGGCCGCA GGACCGGGAG CGGAGCCTCG CAGGATCGGT 180

CTCGGGCTCC CCAACCGCCT CCGCTTCTTT CGCCAGTCGG TGGCCGGGCT GGCGGCGCGG 240

TTGCAGCGGC AGTTCCTGGT GCGGGCCTGG GGCTGCGCGG GCCCTTGCGG CCGGGCAGTC 300

TTTCTGGCCT TCGGGCTAGG GCTGGGCCTC ATCGAGGAGA AGCAGGCGGA GAGCCGACGG 360

GCGGTCTCGG CCTGTCAGGA GATCCAGGCA ATTTTTACCC AGAAAAGCAA GCCAGGGCCT 420

GACCCGTTGG ACACAAGACG CTGGCAGGGC TTTCGGCTGG AGGAGTATCT GATAGGGCAG 480

TCCATTGGCA AGGGCTGCAG TGCCGCTGTG TATGAAGCCA CCATGCCTGC ATTGCCCCAG 540

AACCTGGAGG TGACAAAGAG CACCGGGTCG CTTCCAGGGA GAGGCCCAGG TACCAGTGCA 600

CCAGGAGAAG AGCAGGAGCA AGCTCTGGGG GCCCCTGCCT TCCCCTTGGC CATCAAGATG 660

ATGTGGAACA TCTCGGCAGG TTCCTCCAGC GAAGCTATCT TGAACACAAT GAGCCAGGAG 720

CTGGTCCCAG CGAGCCGAGT GGCCTTGGCC GGGGAGTATG GAGCAGTCAC TTACAGAAAA 780

TCCAAGAGAG GTCCCAAGCA ACTAGCCCCT CACCCCAACA TCATCCGGGT TCTCCGCGCT 840

TTCACCTCTT CCGTGCCGCT GCTACCCGGG GCCCTGGTTG ACTACCCTGA TGTGCTGCCC 900

CCACGCCTCC ACCCTGAAGG CCTGGGCCAC GGCCGGACGC TGTTCCTCGT TATGAAGAAC 960

TATCCCTGTA CCCTGCGCCA GTACCTTCGC GCGAACACAC CCAGCCCCCG CCTCGCCACC 1020

ATGATGATGC TGCAGCTGCT GGAAGGCGTG GACCATCTGG TTCAACAGGG CATCGCGCAC 1080

AGAGACCTGA AATCCGACAA CATCCTTGTG GAGCTGGACC CAGACGGCTG CCCCTGGCTG 1140

GTGATCGCAG ATTTTGGCTG CTGCCTGGCT GATGAGAGCA TCGGCCTGCA GTTGCCCTTC 1200

AGCAGCTGGT ATGTGGATCG GGGCGGAAAC GGCTGCCTGA TGGCCCCAGA GGTGTCCACG 1260

GCCCGTCCTG GCCCCAGGGC AGTGATTGAC TACAGCAAGG CTGATGCCTG GGCAGTGGGA 1320

GCCATCGCCT ATGAAATCTT CGGGCTTGTC AATCCCTTCT ACAGCCAGGG CAAGGCCCAC 1380

CTTGAGAGCC GCAGCTACCA GGAGGCTCAG CTACCTGCAC TGCCCGAGTC GGTGCCTCCA 1440

GACGTGAGAC AGCTGGTGAG GGCACTGCTC CAGCGAGAGG CCAGCAAGAG ACCATCTGCC 1500

CGAGTAGCTG CAAATGTGCT TCATCTAAGC CTCTGGGGTG AACAGATTCT AGCCCTGAAG 1560

AATCTGAAGT TAGATAAGAT GGTTGGCTGG CTTCTCCAAC AATCGGCTGC CACTTTGTTG 1620

GCCAACAGGC TCACAGAGAA GTGTTGTGTG GAAACAAAAA TGAAGATGCT CTTTCTGGCT 1680

AACCTGGAGT GTGAAACGCT CTGCCAGGCA GCCCTCCTTC TCTGCTCATG GAGGGCAGCC 1740

CTGTGA 1746

Domain Profile

S: 1     yligealgkgcnaavyeatlatldqelekakhlgll.gkevtvvlaeidqesavaakkfp  59

         ylig+++gkgc+aavyeat+++l+q+le++k++g l g+++++++++++qe+a +a++fp

Q: 156   YLIGQSIGKGCSAAVYEATMPALPQNLEVTKSTGSLpGRGPGTSAPGEEQEQALGAPAFP  215

         99********************************999***********************

S: 60    laiklmfnieadssseallksmsqelvpasrvaldgeygav........pkllakhPniv  111

         laik+m+ni+a+sssea+l++msqelvpasrval+geygav        pk+la+hPni+

Q: 216   LAIKMMWNISAGSSSEAILNTMSQELVPASRVALAGEYGAVtyrkskrgPKQLAPHPNII  275

         ************************************************************

S: 112   rvlrafidsvkllPdalldyPdalparlypeglgegktlylvmkrydqtlreylesqdrs  171

         rvlraf++sv+llP+al+dyPd+lp+rl+peglg+g+tl+lvmk+y++tlr+yl  +++s

Q: 276   RVLRAFTSSVPLLPGALVDYPDVLPPRLHPEGLGHGRTLFLVMKNYPCTLRQYLRANTPS  335

         ************************************************************

S: 172   trlaalllaqlleavdhlvkhgvahrdlksdnilveldddeiPvlviadfGCcladkvdg  231

         +rla+++++qlle+vdhlv++g+ahrdlksdnilveld+d++P+lviadfGCclad+++g

Q: 336   PRLATMMMLQLLEGVDHLVQQGIAHRDLKSDNILVELDPDGCPWLVIADFGCCLADESIG  395

         ************************************************************

S: 232   lrlpyessevdkGGnaalmaPeistavpGpsavinyekadtWavGalayeifglsnPfyg  291

         l+lp++s++vd+GGn++lmaPe+sta+pGp+avi+y+kad+WavGa+ayeifgl+nPfy

Q: 396   LQLPFSSWYVDRGGNGCLMAPEVSTARPGPRAVIDYSKADAWAVGAIAYEIFGLVNPFYS  455

         ************************************************************

S: 292   egkaslesasyqeaqlPalpesvppelrqlvydllkreaskrvsadiaanvlqlslf  348

         +gka+les+syqeaqlPalpesvpp++rqlv++ll+reaskr+sa++aanvl+lsl+

Q: 456   QGKAHLESRSYQEAQLPALPESVPPDVRQLVRALLQREASKRPSARVAANVLHLSLW  512

         ********************************************************9

Domain Sequence
(FASTA)

YLIGQSIGKG CSAAVYEATM PALPQNLEVT KSTGSLPGRG PGTSAPGEEQ EQALGAPAFP 60

LAIKMMWNIS AGSSSEAILN TMSQELVPAS RVALAGEYGA VTYRKSKRGP KQLAPHPNII 120

RVLRAFTSSV PLLPGALVDY PDVLPPRLHP EGLGHGRTLF LVMKNYPCTL RQYLRANTPS 180

PRLATMMMLQ LLEGVDHLVQ QGIAHRDLKS DNILVELDPD GCPWLVIADF GCCLADESIG 240

LQLPFSSWYV DRGGNGCLMA PEVSTARPGP RAVIDYSKAD AWAVGAIAYE IFGLVNPFYS 300

QGKAHLESRS YQEAQLPALP ESVPPDVRQL VRALLQREAS KRPSARVAAN VLHLSLW 357

Keyword

Complete proteome; Kinase; Reference proteome; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Xiphophorus maculatus"; ?>