EKS-MAM-00132

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-MAM-00132

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Atypical/ABC1	386.7	1.5E-115	170	471	302

Status

Unreviewed

Ensembl Protein

ENSMMUP00000005652

UniProt Accession

F6YXD6;

Protein Name

Protein Synonyms/Alias

AarF domain containing kinase 4 isoform a; Putative aarF domain-containing protein kinase 4 isoform a;

Gene Name

ADCK4

Gene Synonyms/Alias

ADCK4; EGK_10633;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMMUG00000004228	ENSMMUP00000005652	ENSMMUT00000006003
ENSMMUG00000004228	ENSMMUP00000005651	ENSMMUT00000006002

Organism

Macaca mulatta

Functional Description

Protein Length

503

Protein Sequence
(FASTA)

MWLKVGGLLQ GTGGQLGQTV GRPCGALGPG PHHWGPCGGS WAQKFYQGGP GRGLGEEDIR 60

RAREARPRKT PRLQLSDRSR ERKVPASRIS RLANFGGLAV GLGLGALAEM AKKSLPGGHL 120

QSDNSFISPQ LQRIFERVRQ SADFMPRWQM LRVLEEELGR DWQAKVAFLE EVPFAAASIG 180

QVHQGLLKDG TEVAVKIQYP GVAQSIQSDV QNLLAVLKMS TALPAGLFAE QSLQALQQEL 240

AWECDYRREA ACAQNFRQLL ANDPFFRVPA VVKELCTTRV LGMELAGGVP LDQCQGLSQD 300

LRNQICFQLL TLCLRELFEF RFMQTDPNWA NFLYDASSHQ VTLLDFGASR EFGTEFTDHY 360

IEVVKAAADG DRDRVLQKSR DLKFLTGFET KAFSDAHVEA VMILGEPFAT QGPYDFGSGE 420

TARRIQDLIP VLLRHRLRPP PEETYALHRK LAGAFLACAR LQAHIACRDL FQDTYHRYWA 480

SRQPDAATAG SLPTKGDSWA DPS 503

Nucleotide Sequence
(FASTA)

ATGTGGCTGA AGGTGGGGGG CCTACTTCAG GGGACCGGTG GACAGCTGGG CCAGACTGTT 60

GGTCGGCCTT GTGGGGCCCT GGGGCCTGGG CCCCACCACT GGGGGCCATG TGGAGGTTCT 120

TGGGCCCAAA AGTTTTACCA GGGTGGGCCT GGGAGAGGCC TGGGTGAGGA GGACATTCGC 180

AGGGCACGGG AGGCCCGTCC CAGGAAGACA CCCCGGCTCC AGCTGAGTGA CCGCTCTCGA 240

GAACGCAAGG TGCCTGCCTC CCGCATCAGC CGCTTGGCCA ACTTTGGGGG ACTGGCTGTG 300

GGCTTGGGGC TGGGAGCGCT GGCCGAGATG GCTAAGAAGT CCCTGCCAGG AGGTCATCTG 360

CAATCAGACA ACAGCTTCAT CAGCCCTCAG CTGCAGCGCA TCTTCGAGCG GGTCCGCCAG 420

AGCGCCGACT TCATGCCCCG CTGGCAGATG CTGAGAGTTC TTGAAGAGGA GCTTGGCAGG 480

GACTGGCAGG CCAAGGTGGC CTTCTTGGAG GAGGTGCCCT TTGCCGCTGC CTCAATTGGG 540

CAGGTGCACC AGGGCCTGCT GAAGGACGGG ACGGAGGTGG CCGTGAAGAT CCAGTACCCC 600

GGCGTAGCCC AGAGCATTCA GAGCGATGTC CAGAACCTTC TGGCGGTACT CAAGATGAGC 660

ACAGCCCTGC CCGCGGGCCT ATTTGCTGAG CAGAGCCTGC AGGCCTTGCA GCAGGAGCTG 720

GCTTGGGAGT GTGACTACCG TCGTGAGGCA GCTTGTGCCC AGAATTTCAG GCAGCTGCTG 780

GCAAATGACC CCTTCTTCCG GGTGCCAGCT GTGGTTAAGG AGCTGTGCAC GACACGGGTG 840

CTGGGCATGG AGCTGGCCGG AGGAGTCCCC CTGGACCAGT GCCAGGGCCT GAGCCAGGAC 900

CTGCGGAACC AGATTTGCTT CCAGCTCCTG ACGCTGTGTC TGCGGGAGCT GTTTGAGTTC 960

CGATTCATGC AGACGGACCC CAACTGGGCC AACTTCCTAT ATGACGCCTC CAGCCACCAG 1020

GTGACCCTGC TGGACTTTGG TGCAAGCCGG GAGTTTGGGA CAGAGTTCAC AGACCATTAC 1080

ATCGAGGTGG TGAAGGCTGC AGCTGACGGA GACAGAGACC GTGTCCTACA GAAGTCCAGG 1140

GACCTCAAAT TCCTCACAGG CTTTGAAACC AAGGCATTCT CCGACGCCCA CGTGGAGGCA 1200

GTGATGATCC TGGGGGAGCC CTTCGCCACC CAGGGCCCTT ATGACTTTGG GTCGGGGGAA 1260

ACTGCCCGCC GCATCCAGGA CCTCATCCCG GTGCTGCTGC GGCACCGGCT GCGCCCCCCA 1320

CCCGAGGAGA CCTATGCCCT GCACCGCAAG CTGGCAGGGG CTTTCCTGGC CTGTGCCCGC 1380

CTCCAAGCTC ACATCGCCTG CAGGGACCTC TTCCAGGACA CCTACCACCG CTACTGGGCC 1440

AGTCGCCAGC CAGACGCAGC CACTGCCGGC AGCCTCCCCA CCAAAGGAGA CTCCTGGGCA 1500

GATCCCTCAT GA 1512

Domain Profile

S: 1     eekPlaaASlaqvhkArLkdGeeVAVKvqypgvkesidsDlktlelllkvlevlfkdlkl  60

         ee P+aaAS++qvh++ LkdG+eVAVK+qypgv++si+sD+++l ++lk++ +l+ +l+

Q: 170   EEVPFAAASIGQVHQGLLKDGTEVAVKIQYPGVAQSIQSDVQNLLAVLKMSTALPAGLFA  229

         689*********************************************************

S: 61    ewlvdelkkeLaleldferEarnaekfrkllkkfkalkvPkvleelstkrvLtmelvegv  120

         e+ ++ l++eLa+e+d++rEa++a++fr+ll+++++++vP+v++el+t+rvL mel++gv

Q: 230   EQSLQALQQELAWECDYRREAACAQNFRQLLANDPFFRVPAVVKELCTTRVLGMELAGGV  289

         ************************************************************

S: 121   pvddleyiessqilrneiaekliklllkeifvdnfvhtDphpgNvlvqksskegklelvL  180

         p+d+++  + sq+lrn+i+ +l++l+l+e+f+++f++tDp+++N+l+++ss+    +++L

Q: 290   PLDQCQ--GLSQDLRNQICFQLLTLCLRELFEFRFMQTDPNWANFLYDASSH----QVTL  343

         ******..********************************************....****

S: 181   LDfGlsrelsekfrrlyikllkavvdrDrkkvkkksqrlaeltgeeaklladalvervlt  240

         LDfG+sre++++f+++yi+++ka++d Dr++v +ks++l++ltg e+k+++da+ve+v++

Q: 344   LDFGASREFGTEFTDHYIEVVKAAADGDRDRVLQKSRDLKFLTGFETKAFSDAHVEAVMI  403

         ************************************************************

S: 241   lgeafasqarkeveeleklaverlessllkllmevlvklprevllilktidllrgieeaL  300

         lge+fa+q   ++++++ ++++r+++++++ll+++l+++p+e++++++++++++  ++ L

Q: 404   LGEPFATQ--GPYDFGSGETARRIQDLIPVLLRHRLRPPPEETYALHRKLAGAFLACARL  461

         ********..**************************************************

S: 301   kakldilell  310

         +a++++++l+

Q: 462   QAHIACRDLF  471

         ******9875

Domain Sequence
(FASTA)

EEVPFAAASI GQVHQGLLKD GTEVAVKIQY PGVAQSIQSD VQNLLAVLKM STALPAGLFA 60

EQSLQALQQE LAWECDYRRE AACAQNFRQL LANDPFFRVP AVVKELCTTR VLGMELAGGV 120

PLDQCQGLSQ DLRNQICFQL LTLCLRELFE FRFMQTDPNW ANFLYDASSH QVTLLDFGAS 180

REFGTEFTDH YIEVVKAAAD GDRDRVLQKS RDLKFLTGFE TKAFSDAHVE AVMILGEPFA 240

TQGPYDFGSG ETARRIQDLI PVLLRHRLRP PPEETYALHR KLAGAFLACA RLQAHIACRD 300

LF 302

Keyword

Complete proteome; Kinase; Reference proteome; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Dipodomys ordii"; ?>Equus caballus"; ?>Felis catus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Takifugu rubripes"; ?>Tursiops truncatus"; ?>